Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	GMP.GMP.neu_Pheno.cls #Group3_versus_Group4.GMP.neu_Pheno.cls #Group3_versus_Group4_repos
Phenotype	GMP.neu_Pheno.cls#Group3_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.16100794
Normalized Enrichment Score (NES)	-0.6607496
Nominal p-value	0.7975708
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Depdc1a	579	0.586	-0.0104	No
2	Cdc25b	809	0.539	-0.0047	No
3	Cdkn2c	1158	0.484	-0.0068	No
4	Mad2l1	1212	0.476	0.0058	No
5	Cdkn3	1688	0.424	-0.0046	No
6	Ncapd2	1797	0.412	0.0031	No
7	Melk	2205	0.372	-0.0055	No
8	Rnaseh2a	2283	0.367	0.0024	No
9	Mxd3	2835	0.326	-0.0149	No
10	Kif18b	3303	0.300	-0.0289	No
11	Tubg1	3547	0.286	-0.0320	No
12	Dlgap5	3567	0.284	-0.0239	No
13	Ung	3637	0.279	-0.0184	No
14	Asf1b	3654	0.278	-0.0103	No
15	Espl1	3688	0.276	-0.0032	No
16	Myc	3693	0.275	0.0054	No
17	Mybl2	3823	0.265	0.0074	No
18	Cenpm	3850	0.263	0.0145	No
19	Cdc20	3865	0.262	0.0222	No
20	Xrcc6	3883	0.261	0.0297	No
21	H2ax	3909	0.260	0.0367	No
22	Timeless	4181	0.246	0.0309	No
23	Hmga1b	4218	0.244	0.0369	No
24	Dscc1	4266	0.241	0.0423	No
25	Pole4	4554	0.228	0.0351	No
26	Aurkb	4560	0.228	0.0422	No
27	Tubb5	4763	0.218	0.0389	No
28	Smc1a	4971	0.206	0.0351	No
29	Ing3	5095	0.201	0.0353	No
30	Phf5a	5214	0.195	0.0356	No
31	Ctcf	5310	0.190	0.0369	No
32	Tacc3	5326	0.190	0.0422	No
33	Dck	5634	0.177	0.0324	No
34	Spc24	5671	0.176	0.0362	No
35	Spag5	5673	0.175	0.0418	No
36	Msh2	5705	0.173	0.0458	No
37	Wdr90	5814	0.168	0.0457	No
38	Xpo1	5856	0.166	0.0490	No
39	Lmnb1	5937	0.163	0.0502	No
40	Snrpb	5966	0.162	0.0540	No
41	Rfc1	6112	0.155	0.0516	No
42	Cse1l	6399	0.142	0.0417	No
43	Ccnb2	6446	0.140	0.0439	No
44	Srsf1	6515	0.136	0.0448	No
45	Ssrp1	6634	0.130	0.0430	No
46	Nop56	6739	0.126	0.0418	No
47	Pold1	6879	0.121	0.0387	No
48	Jpt1	6914	0.119	0.0408	No
49	Tmpo	6923	0.119	0.0442	No
50	Cdk4	7251	0.113	0.0313	No
51	Plk1	7325	0.109	0.0311	No
52	Ube2t	7461	0.104	0.0277	No
53	Hmmr	7594	0.099	0.0242	No
54	Dctpp1	7861	0.089	0.0136	No
55	Mcm5	8118	0.078	0.0032	No
56	Ddx39a	8249	0.074	-0.0010	No
57	Bard1	8315	0.071	-0.0020	No
58	Srsf2	8366	0.069	-0.0023	No
59	Ezh2	8370	0.069	-0.0002	No
60	Mcm7	8428	0.066	-0.0010	No
61	Eed	8546	0.062	-0.0049	No
62	Ak2	8658	0.057	-0.0087	No
63	Top2a	8660	0.057	-0.0069	No
64	Mcm6	8739	0.054	-0.0091	No
65	Cks1b	8819	0.051	-0.0115	No
66	Rfc2	8827	0.050	-0.0102	No
67	Pold3	9039	0.042	-0.0195	No
68	Ranbp1	9176	0.037	-0.0252	No
69	Atad2	9352	0.032	-0.0330	No
70	Nap1l1	9360	0.031	-0.0324	No
71	Mcm4	9367	0.031	-0.0317	No
72	Mthfd2	9380	0.030	-0.0313	No
73	Slbp	9403	0.029	-0.0315	No
74	Lig1	9413	0.029	-0.0310	No
75	Pold2	9417	0.029	-0.0302	No
76	Asf1a	9686	0.020	-0.0431	No
77	Tk1	9690	0.019	-0.0426	No
78	Paics	9807	0.015	-0.0480	No
79	Ppm1d	9839	0.014	-0.0491	No
80	Cbx5	9856	0.014	-0.0495	No
81	Bub1b	9876	0.013	-0.0500	No
82	Birc5	9957	0.011	-0.0537	No
83	Hmgb2	9961	0.010	-0.0535	No
84	Rad1	9989	0.010	-0.0546	No
85	Ccp110	10091	0.006	-0.0595	No
86	Hnrnpd	10174	0.002	-0.0635	No
87	Smc4	10235	0.000	-0.0666	No
88	Cnot9	10551	-0.004	-0.0823	No
89	Cdk1	10637	-0.006	-0.0864	No
90	Ppp1r8	10648	-0.007	-0.0867	No
91	Tipin	10678	-0.008	-0.0879	No
92	Dek	10729	-0.010	-0.0901	No
93	Diaph3	10734	-0.010	-0.0900	No
94	Prim2	10745	-0.010	-0.0902	No
95	Ilf3	10779	-0.011	-0.0915	No
96	Rbbp7	10810	-0.013	-0.0926	No
97	Syncrip	10816	-0.013	-0.0925	No
98	Nme1	10824	-0.013	-0.0924	No
99	Pa2g4	10879	-0.015	-0.0946	No
100	Smc6	10903	-0.016	-0.0953	No
101	Lsm8	11059	-0.021	-0.1024	No
102	Psip1	11132	-0.023	-0.1053	No
103	Lbr	11159	-0.024	-0.1058	No
104	Eif2s1	11244	-0.027	-0.1092	No
105	Dnmt1	11266	-0.028	-0.1094	No
106	Anp32e	11268	-0.028	-0.1085	No
107	H2az1	11287	-0.029	-0.1085	No
108	Rad21	11340	-0.031	-0.1101	No
109	Ipo7	11404	-0.033	-0.1122	No
110	Lyar	11627	-0.040	-0.1221	No
111	Plk4	11770	-0.045	-0.1279	No
112	Pds5b	11877	-0.049	-0.1316	No
113	Prps1	11959	-0.052	-0.1340	No
114	Pcna	12050	-0.054	-0.1369	No
115	Shmt1	12148	-0.058	-0.1399	No
116	Kif2c	12149	-0.058	-0.1380	No
117	Mcm3	12175	-0.059	-0.1374	No
118	Gspt1	12245	-0.061	-0.1389	No
119	Gins3	12591	-0.073	-0.1540	No
120	Stag1	12605	-0.074	-0.1523	No
121	Pan2	12641	-0.075	-0.1516	No
122	Mre11a	12655	-0.076	-0.1499	No
123	Nasp	12658	-0.076	-0.1475	No
124	Cenpe	12663	-0.076	-0.1453	No
125	Suv39h1	12753	-0.079	-0.1472	No
126	Mki67	12797	-0.081	-0.1468	No
127	Nup205	12832	-0.082	-0.1459	No
128	Wee1	12923	-0.086	-0.1477	No
129	Smc3	13013	-0.089	-0.1494	No
130	Brca2	13041	-0.090	-0.1479	No
131	Mcm2	13051	-0.090	-0.1454	No
132	Cdc25a	13254	-0.097	-0.1525	No
133	Rad50	13350	-0.100	-0.1541	No
134	Nudt21	13380	-0.102	-0.1523	No
135	Kif4	13455	-0.104	-0.1527	No
136	Brms1l	13474	-0.105	-0.1502	No
137	Luc7l3	13508	-0.106	-0.1485	No
138	Mms22l	13548	-0.108	-0.1470	No
139	Chek2	13590	-0.109	-0.1456	No
140	Nolc1	13677	-0.112	-0.1463	No
141	Trp53	13969	-0.123	-0.1571	Yes
142	Pms2	13982	-0.124	-0.1537	Yes
143	Dclre1b	13983	-0.124	-0.1497	Yes
144	Rad51c	14061	-0.128	-0.1495	Yes
145	Nup153	14130	-0.131	-0.1488	Yes
146	Cdca3	14270	-0.137	-0.1514	Yes
147	Prkdc	14355	-0.140	-0.1512	Yes
148	Aurka	14452	-0.143	-0.1514	Yes
149	Rpa3	14486	-0.145	-0.1485	Yes
150	Stmn1	14571	-0.148	-0.1480	Yes
151	Spc25	14677	-0.152	-0.1484	Yes
152	Pop7	14705	-0.153	-0.1449	Yes
153	Nup107	14900	-0.162	-0.1494	Yes
154	Tcf19	14925	-0.163	-0.1454	Yes
155	Rpa1	15029	-0.168	-0.1453	Yes
156	Kif22	15057	-0.169	-0.1412	Yes
157	Tbrg4	15141	-0.171	-0.1399	Yes
158	Brca1	15149	-0.172	-0.1348	Yes
159	Cdca8	15203	-0.174	-0.1319	Yes
160	Cit	15282	-0.179	-0.1301	Yes
161	Pole	15444	-0.182	-0.1324	Yes
162	Pnn	15449	-0.182	-0.1268	Yes
163	Chek1	15618	-0.190	-0.1292	Yes
164	E2f8	15773	-0.197	-0.1306	Yes
165	Racgap1	15913	-0.204	-0.1311	Yes
166	Usp1	15974	-0.207	-0.1275	Yes
167	Zw10	16011	-0.210	-0.1226	Yes
168	Tra2b	16140	-0.213	-0.1222	Yes
169	Ubr7	16155	-0.214	-0.1161	Yes
170	Hus1	16267	-0.219	-0.1147	Yes
171	Hmgb3	16368	-0.225	-0.1125	Yes
172	Mlh1	16499	-0.232	-0.1116	Yes
173	Nbn	16615	-0.239	-0.1098	Yes
174	Orc2	16867	-0.254	-0.1143	Yes
175	Pola2	16902	-0.257	-0.1078	Yes
176	Donson	17041	-0.266	-0.1063	Yes
177	Cks2	17351	-0.279	-0.1129	Yes
178	Rrm2	17440	-0.284	-0.1082	Yes
179	Cdkn1b	17463	-0.287	-0.1002	Yes
180	Exosc8	17583	-0.295	-0.0967	Yes
181	Trip13	17608	-0.297	-0.0885	Yes
182	Rfc3	17609	-0.297	-0.0790	Yes
183	Gins4	17811	-0.311	-0.0791	Yes
184	Dut	17853	-0.314	-0.0711	Yes
185	Orc6	17994	-0.322	-0.0679	Yes
186	Pttg1	18372	-0.350	-0.0757	Yes
187	Hells	18417	-0.355	-0.0665	Yes
188	Psmc3ip	18461	-0.359	-0.0572	Yes
189	Ran	18635	-0.376	-0.0539	Yes
190	Ccne1	18765	-0.394	-0.0478	Yes
191	Ube2s	18948	-0.416	-0.0437	Yes
192	Rpa2	19190	-0.447	-0.0415	Yes
193	Tfrc	19227	-0.454	-0.0288	Yes
194	Gins1	19441	-0.495	-0.0237	Yes
195	Cdkn1a	19498	-0.508	-0.0102	Yes
196	Prdx4	19664	-0.558	-0.0007	Yes
197	Rad51ap1	19757	-0.591	0.0136	Yes