| Dataset | GMP.GMP.neu_Pheno.cls #Group2_versus_Group4.GMP.neu_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.39541852 |
| Normalized Enrichment Score (NES) | 1.7451614 |
| Nominal p-value | 0.034764826 |
| FDR q-value | 0.04282671 |
| FWER p-Value | 0.079 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 49 | 0.914 | 0.0156 | Yes |
| 2 | Hspa8 | 54 | 0.902 | 0.0333 | Yes |
| 3 | Kpnb1 | 87 | 0.854 | 0.0485 | Yes |
| 4 | Cdkn2c | 159 | 0.777 | 0.0603 | Yes |
| 5 | Nek2 | 189 | 0.747 | 0.0737 | Yes |
| 6 | Sqle | 198 | 0.741 | 0.0879 | Yes |
| 7 | Hnrnpu | 341 | 0.664 | 0.0939 | Yes |
| 8 | Xpo1 | 391 | 0.646 | 0.1042 | Yes |
| 9 | Ube2c | 401 | 0.642 | 0.1165 | Yes |
| 10 | Ccna2 | 464 | 0.624 | 0.1257 | Yes |
| 11 | Ddx39a | 493 | 0.617 | 0.1365 | Yes |
| 12 | Upf1 | 520 | 0.612 | 0.1473 | Yes |
| 13 | Bcl3 | 695 | 0.568 | 0.1498 | Yes |
| 14 | Lig3 | 738 | 0.558 | 0.1587 | Yes |
| 15 | Cdc25b | 805 | 0.546 | 0.1662 | Yes |
| 16 | Odc1 | 820 | 0.543 | 0.1762 | Yes |
| 17 | Jpt1 | 905 | 0.527 | 0.1824 | Yes |
| 18 | G3bp1 | 941 | 0.520 | 0.1909 | Yes |
| 19 | Ndc80 | 955 | 0.518 | 0.2005 | Yes |
| 20 | Lmnb1 | 1066 | 0.501 | 0.2049 | Yes |
| 21 | E2f4 | 1094 | 0.496 | 0.2133 | Yes |
| 22 | Incenp | 1113 | 0.494 | 0.2222 | Yes |
| 23 | Hmmr | 1270 | 0.472 | 0.2237 | Yes |
| 24 | Lbr | 1449 | 0.453 | 0.2236 | Yes |
| 25 | Dr1 | 1453 | 0.452 | 0.2324 | Yes |
| 26 | Smc1a | 1455 | 0.452 | 0.2413 | Yes |
| 27 | Cenpf | 1558 | 0.440 | 0.2449 | Yes |
| 28 | Kif11 | 1640 | 0.432 | 0.2493 | Yes |
| 29 | Sfpq | 1653 | 0.431 | 0.2573 | Yes |
| 30 | Cdc6 | 1756 | 0.422 | 0.2605 | Yes |
| 31 | Prc1 | 1963 | 0.404 | 0.2581 | Yes |
| 32 | Rad23b | 1970 | 0.403 | 0.2658 | Yes |
| 33 | Top2a | 2003 | 0.401 | 0.2721 | Yes |
| 34 | Amd1 | 2105 | 0.396 | 0.2748 | Yes |
| 35 | Rad21 | 2106 | 0.396 | 0.2827 | Yes |
| 36 | Bub1 | 2124 | 0.394 | 0.2896 | Yes |
| 37 | Plk4 | 2127 | 0.394 | 0.2973 | Yes |
| 38 | Syncrip | 2180 | 0.389 | 0.3024 | Yes |
| 39 | Ccnf | 2218 | 0.385 | 0.3081 | Yes |
| 40 | Cdc7 | 2239 | 0.384 | 0.3147 | Yes |
| 41 | Dbf4 | 2254 | 0.382 | 0.3216 | Yes |
| 42 | Nup98 | 2264 | 0.381 | 0.3287 | Yes |
| 43 | Cenpe | 2310 | 0.378 | 0.3339 | Yes |
| 44 | Racgap1 | 2316 | 0.377 | 0.3411 | Yes |
| 45 | Plk1 | 2425 | 0.371 | 0.3430 | Yes |
| 46 | Mybl2 | 2517 | 0.364 | 0.3456 | Yes |
| 47 | H2bc12 | 2629 | 0.354 | 0.3470 | Yes |
| 48 | Hif1a | 2678 | 0.351 | 0.3515 | Yes |
| 49 | Tpx2 | 2769 | 0.347 | 0.3538 | Yes |
| 50 | Ncl | 3160 | 0.319 | 0.3405 | Yes |
| 51 | Nolc1 | 3174 | 0.318 | 0.3461 | Yes |
| 52 | Kif4 | 3387 | 0.307 | 0.3415 | Yes |
| 53 | Tacc3 | 3420 | 0.305 | 0.3459 | Yes |
| 54 | Espl1 | 3469 | 0.302 | 0.3495 | Yes |
| 55 | Mki67 | 3471 | 0.302 | 0.3554 | Yes |
| 56 | Mcm5 | 3472 | 0.302 | 0.3614 | Yes |
| 57 | Uck2 | 3532 | 0.297 | 0.3643 | Yes |
| 58 | Hnrnpd | 3622 | 0.292 | 0.3656 | Yes |
| 59 | Cul1 | 3677 | 0.290 | 0.3686 | Yes |
| 60 | Kif20b | 3729 | 0.287 | 0.3717 | Yes |
| 61 | Mcm3 | 3845 | 0.281 | 0.3715 | Yes |
| 62 | Mad2l1 | 3884 | 0.278 | 0.3751 | Yes |
| 63 | Mcm2 | 3914 | 0.276 | 0.3791 | Yes |
| 64 | Tnpo2 | 4094 | 0.267 | 0.3753 | Yes |
| 65 | Aurkb | 4318 | 0.253 | 0.3691 | Yes |
| 66 | Birc5 | 4364 | 0.251 | 0.3718 | Yes |
| 67 | Nasp | 4386 | 0.250 | 0.3757 | Yes |
| 68 | Tent4a | 4400 | 0.249 | 0.3800 | Yes |
| 69 | Cks2 | 4410 | 0.249 | 0.3844 | Yes |
| 70 | Tmpo | 4483 | 0.243 | 0.3856 | Yes |
| 71 | Tfdp1 | 4594 | 0.239 | 0.3848 | Yes |
| 72 | Odf2 | 4856 | 0.225 | 0.3761 | Yes |
| 73 | Notch2 | 4939 | 0.220 | 0.3763 | Yes |
| 74 | Wrn | 5071 | 0.213 | 0.3739 | Yes |
| 75 | Cdc25a | 5099 | 0.212 | 0.3768 | Yes |
| 76 | Numa1 | 5150 | 0.210 | 0.3784 | Yes |
| 77 | Top1 | 5276 | 0.204 | 0.3761 | Yes |
| 78 | Smc2 | 5339 | 0.200 | 0.3770 | Yes |
| 79 | E2f2 | 5366 | 0.198 | 0.3796 | Yes |
| 80 | Slc38a1 | 5429 | 0.195 | 0.3803 | Yes |
| 81 | Cdc20 | 5472 | 0.192 | 0.3820 | Yes |
| 82 | Cdkn1b | 5687 | 0.187 | 0.3749 | Yes |
| 83 | Gspt1 | 5689 | 0.186 | 0.3785 | Yes |
| 84 | Polq | 5719 | 0.184 | 0.3807 | Yes |
| 85 | Ttk | 5760 | 0.182 | 0.3823 | Yes |
| 86 | Bard1 | 5831 | 0.178 | 0.3823 | Yes |
| 87 | Chaf1a | 5847 | 0.178 | 0.3851 | Yes |
| 88 | Hira | 5881 | 0.176 | 0.3869 | Yes |
| 89 | Ctcf | 5900 | 0.175 | 0.3895 | Yes |
| 90 | Kif15 | 6066 | 0.168 | 0.3845 | Yes |
| 91 | Rbl1 | 6086 | 0.167 | 0.3868 | Yes |
| 92 | Kif23 | 6127 | 0.166 | 0.3881 | Yes |
| 93 | Mcm6 | 6138 | 0.166 | 0.3909 | Yes |
| 94 | Cul3 | 6158 | 0.165 | 0.3932 | Yes |
| 95 | Slc7a1 | 6210 | 0.162 | 0.3938 | Yes |
| 96 | Gins2 | 6256 | 0.159 | 0.3947 | Yes |
| 97 | Ccnt1 | 6304 | 0.157 | 0.3954 | Yes |
| 98 | Cdk1 | 6388 | 0.153 | 0.3943 | No |
| 99 | Ilf3 | 6551 | 0.147 | 0.3890 | No |
| 100 | Map3k20 | 6625 | 0.143 | 0.3881 | No |
| 101 | Atrx | 6708 | 0.138 | 0.3867 | No |
| 102 | Aurka | 6866 | 0.129 | 0.3814 | No |
| 103 | Stil | 6931 | 0.126 | 0.3807 | No |
| 104 | Meis2 | 6936 | 0.126 | 0.3830 | No |
| 105 | Chmp1a | 7067 | 0.120 | 0.3788 | No |
| 106 | Cenpa | 7155 | 0.116 | 0.3767 | No |
| 107 | Smarcc1 | 7345 | 0.110 | 0.3693 | No |
| 108 | H2az1 | 7365 | 0.109 | 0.3705 | No |
| 109 | Atf5 | 7486 | 0.103 | 0.3665 | No |
| 110 | Ccnb2 | 7541 | 0.101 | 0.3658 | No |
| 111 | Nsd2 | 7597 | 0.098 | 0.3650 | No |
| 112 | Stag1 | 8013 | 0.082 | 0.3457 | No |
| 113 | Pafah1b1 | 8014 | 0.082 | 0.3473 | No |
| 114 | Kif2c | 8082 | 0.080 | 0.3455 | No |
| 115 | Cks1b | 8109 | 0.078 | 0.3457 | No |
| 116 | Fancc | 8118 | 0.078 | 0.3469 | No |
| 117 | Nusap1 | 8120 | 0.078 | 0.3484 | No |
| 118 | Ewsr1 | 8152 | 0.077 | 0.3483 | No |
| 119 | Cul4a | 8261 | 0.072 | 0.3443 | No |
| 120 | Mtf2 | 8311 | 0.069 | 0.3432 | No |
| 121 | Mapk14 | 8399 | 0.065 | 0.3401 | No |
| 122 | Cdc27 | 8415 | 0.064 | 0.3406 | No |
| 123 | Prpf4b | 8454 | 0.063 | 0.3399 | No |
| 124 | Cul5 | 8467 | 0.062 | 0.3406 | No |
| 125 | Ss18 | 8531 | 0.061 | 0.3386 | No |
| 126 | Bub3 | 8547 | 0.060 | 0.3390 | No |
| 127 | Troap | 8568 | 0.059 | 0.3392 | No |
| 128 | Sap30 | 8599 | 0.058 | 0.3388 | No |
| 129 | Hmga1b | 8807 | 0.048 | 0.3293 | No |
| 130 | Kmt5a | 8925 | 0.043 | 0.3243 | No |
| 131 | Cdkn3 | 9031 | 0.039 | 0.3198 | No |
| 132 | H2ax | 9059 | 0.038 | 0.3192 | No |
| 133 | Slc7a5 | 9269 | 0.029 | 0.3092 | No |
| 134 | Srsf2 | 9350 | 0.025 | 0.3057 | No |
| 135 | Pbk | 9407 | 0.022 | 0.3033 | No |
| 136 | Tra2b | 9426 | 0.021 | 0.3028 | No |
| 137 | Marcks | 9567 | 0.015 | 0.2960 | No |
| 138 | Suv39h1 | 9680 | 0.010 | 0.2906 | No |
| 139 | Prmt5 | 9707 | 0.008 | 0.2894 | No |
| 140 | Rad54l | 9784 | 0.005 | 0.2857 | No |
| 141 | Nup50 | 9966 | -0.001 | 0.2766 | No |
| 142 | Kif5b | 9984 | -0.001 | 0.2758 | No |
| 143 | Smc4 | 10013 | -0.003 | 0.2744 | No |
| 144 | Arid4a | 10139 | -0.009 | 0.2683 | No |
| 145 | Dtymk | 10288 | -0.014 | 0.2611 | No |
| 146 | Ythdc1 | 10384 | -0.018 | 0.2566 | No |
| 147 | Kif22 | 10547 | -0.025 | 0.2490 | No |
| 148 | Dmd | 10716 | -0.031 | 0.2411 | No |
| 149 | Casp8ap2 | 10974 | -0.043 | 0.2290 | No |
| 150 | Ezh2 | 11050 | -0.045 | 0.2261 | No |
| 151 | Knl1 | 11082 | -0.047 | 0.2255 | No |
| 152 | E2f3 | 11091 | -0.047 | 0.2260 | No |
| 153 | Prim2 | 11304 | -0.057 | 0.2165 | No |
| 154 | Smad3 | 11443 | -0.064 | 0.2108 | No |
| 155 | Fbxo5 | 11588 | -0.071 | 0.2049 | No |
| 156 | Ube2s | 11608 | -0.072 | 0.2054 | No |
| 157 | Traip | 11716 | -0.076 | 0.2015 | No |
| 158 | Abl1 | 11906 | -0.087 | 0.1937 | No |
| 159 | Chek1 | 12036 | -0.092 | 0.1890 | No |
| 160 | Myc | 12714 | -0.119 | 0.1572 | No |
| 161 | Pds5b | 12746 | -0.120 | 0.1580 | No |
| 162 | Orc5 | 12821 | -0.123 | 0.1567 | No |
| 163 | Exo1 | 12881 | -0.126 | 0.1562 | No |
| 164 | Foxn3 | 13002 | -0.133 | 0.1528 | No |
| 165 | Snrpd1 | 13059 | -0.135 | 0.1527 | No |
| 166 | Pml | 13237 | -0.143 | 0.1466 | No |
| 167 | Brca2 | 13804 | -0.171 | 0.1214 | No |
| 168 | Srsf10 | 13843 | -0.173 | 0.1229 | No |
| 169 | Rasal2 | 14024 | -0.182 | 0.1175 | No |
| 170 | Dkc1 | 14157 | -0.189 | 0.1146 | No |
| 171 | Cdk4 | 14186 | -0.190 | 0.1169 | No |
| 172 | Tle3 | 14351 | -0.198 | 0.1125 | No |
| 173 | Pttg1 | 14471 | -0.203 | 0.1106 | No |
| 174 | Cbx1 | 14651 | -0.212 | 0.1057 | No |
| 175 | Tgfb1 | 14901 | -0.224 | 0.0976 | No |
| 176 | Rps6ka5 | 15332 | -0.243 | 0.0807 | No |
| 177 | Cdc45 | 15385 | -0.246 | 0.0830 | No |
| 178 | Mnat1 | 15670 | -0.261 | 0.0738 | No |
| 179 | Meis1 | 16074 | -0.283 | 0.0591 | No |
| 180 | Hus1 | 16165 | -0.288 | 0.0603 | No |
| 181 | Hmgb3 | 16994 | -0.337 | 0.0252 | No |
| 182 | Pole | 17083 | -0.344 | 0.0275 | No |
| 183 | Pola2 | 17572 | -0.380 | 0.0105 | No |
| 184 | Efna5 | 17657 | -0.386 | 0.0139 | No |
| 185 | E2f1 | 18140 | -0.430 | -0.0019 | No |
| 186 | Rpa2 | 18208 | -0.437 | 0.0033 | No |
| 187 | Ccnd1 | 18272 | -0.442 | 0.0089 | No |
| 188 | Orc6 | 18584 | -0.477 | 0.0027 | No |
| 189 | Slc12a2 | 18695 | -0.487 | 0.0068 | No |
| 190 | Pura | 18716 | -0.489 | 0.0154 | No |
| 191 | H2az2 | 18736 | -0.491 | 0.0242 | No |
| 192 | Katna1 | 19053 | -0.538 | 0.0189 | No |
| 193 | Egf | 19660 | -0.691 | 0.0020 | No |
| 194 | Stmn1 | 19880 | -0.828 | 0.0074 | No |

