| Dataset | GMP.GMP.neu_Pheno.cls #Group2_versus_Group4.GMP.neu_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.29014874 |
| Normalized Enrichment Score (NES) | 1.2947493 |
| Nominal p-value | 0.18458419 |
| FDR q-value | 0.44135123 |
| FWER p-Value | 0.763 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 49 | 0.914 | 0.0163 | Yes |
| 2 | Ccp110 | 125 | 0.811 | 0.0291 | Yes |
| 3 | Dck | 128 | 0.806 | 0.0456 | Yes |
| 4 | Cdkn2c | 159 | 0.777 | 0.0600 | Yes |
| 5 | Xpo1 | 391 | 0.646 | 0.0616 | Yes |
| 6 | Dnmt1 | 447 | 0.629 | 0.0717 | Yes |
| 7 | Ncapd2 | 461 | 0.625 | 0.0839 | Yes |
| 8 | Ddx39a | 493 | 0.617 | 0.0950 | Yes |
| 9 | Ung | 685 | 0.570 | 0.0971 | Yes |
| 10 | Cdc25b | 805 | 0.546 | 0.1023 | Yes |
| 11 | Jpt1 | 905 | 0.527 | 0.1081 | Yes |
| 12 | Bub1b | 980 | 0.514 | 0.1149 | Yes |
| 13 | Lmnb1 | 1066 | 0.501 | 0.1209 | Yes |
| 14 | Ipo7 | 1130 | 0.492 | 0.1278 | Yes |
| 15 | Zw10 | 1190 | 0.483 | 0.1347 | Yes |
| 16 | Hmmr | 1270 | 0.472 | 0.1404 | Yes |
| 17 | Lbr | 1449 | 0.453 | 0.1407 | Yes |
| 18 | Smc1a | 1455 | 0.452 | 0.1498 | Yes |
| 19 | Cse1l | 1501 | 0.447 | 0.1566 | Yes |
| 20 | Phf5a | 1626 | 0.434 | 0.1593 | Yes |
| 21 | Depdc1a | 1869 | 0.414 | 0.1556 | Yes |
| 22 | Top2a | 2003 | 0.401 | 0.1571 | Yes |
| 23 | Rad21 | 2106 | 0.396 | 0.1601 | Yes |
| 24 | Plk4 | 2127 | 0.394 | 0.1671 | Yes |
| 25 | Syncrip | 2180 | 0.389 | 0.1725 | Yes |
| 26 | Cbx5 | 2233 | 0.384 | 0.1778 | Yes |
| 27 | Dlgap5 | 2289 | 0.379 | 0.1828 | Yes |
| 28 | Ak2 | 2300 | 0.379 | 0.1900 | Yes |
| 29 | Cenpe | 2310 | 0.378 | 0.1973 | Yes |
| 30 | Racgap1 | 2316 | 0.377 | 0.2048 | Yes |
| 31 | Melk | 2358 | 0.374 | 0.2104 | Yes |
| 32 | Xrcc6 | 2371 | 0.373 | 0.2175 | Yes |
| 33 | Ssrp1 | 2394 | 0.372 | 0.2240 | Yes |
| 34 | Plk1 | 2425 | 0.371 | 0.2301 | Yes |
| 35 | Mybl2 | 2517 | 0.364 | 0.2329 | Yes |
| 36 | Anp32e | 2899 | 0.337 | 0.2206 | Yes |
| 37 | Atad2 | 3037 | 0.327 | 0.2204 | Yes |
| 38 | Smc3 | 3077 | 0.324 | 0.2251 | Yes |
| 39 | Nolc1 | 3174 | 0.318 | 0.2268 | Yes |
| 40 | Lsm8 | 3382 | 0.307 | 0.2227 | Yes |
| 41 | Kif4 | 3387 | 0.307 | 0.2288 | Yes |
| 42 | Tacc3 | 3420 | 0.305 | 0.2334 | Yes |
| 43 | Espl1 | 3469 | 0.302 | 0.2372 | Yes |
| 44 | Mki67 | 3471 | 0.302 | 0.2433 | Yes |
| 45 | Mcm5 | 3472 | 0.302 | 0.2495 | Yes |
| 46 | Hnrnpd | 3622 | 0.292 | 0.2480 | Yes |
| 47 | Ppp1r8 | 3686 | 0.290 | 0.2508 | Yes |
| 48 | Mcm4 | 3705 | 0.289 | 0.2558 | Yes |
| 49 | Rrm2 | 3748 | 0.285 | 0.2595 | Yes |
| 50 | Mcm3 | 3845 | 0.281 | 0.2604 | Yes |
| 51 | Mad2l1 | 3884 | 0.278 | 0.2642 | Yes |
| 52 | Ccne1 | 3888 | 0.278 | 0.2698 | Yes |
| 53 | Mcm2 | 3914 | 0.276 | 0.2742 | Yes |
| 54 | Cdca8 | 3958 | 0.273 | 0.2776 | Yes |
| 55 | Lyar | 4077 | 0.268 | 0.2771 | Yes |
| 56 | Aurkb | 4318 | 0.253 | 0.2702 | Yes |
| 57 | Birc5 | 4364 | 0.251 | 0.2731 | Yes |
| 58 | Nasp | 4386 | 0.250 | 0.2772 | Yes |
| 59 | Cks2 | 4410 | 0.249 | 0.2811 | Yes |
| 60 | Hmgb2 | 4420 | 0.248 | 0.2858 | Yes |
| 61 | Tmpo | 4483 | 0.243 | 0.2876 | Yes |
| 62 | Rfc1 | 4653 | 0.237 | 0.2840 | Yes |
| 63 | Pcna | 4692 | 0.235 | 0.2869 | Yes |
| 64 | Mxd3 | 4729 | 0.233 | 0.2898 | Yes |
| 65 | Mre11a | 4994 | 0.217 | 0.2810 | Yes |
| 66 | Cdc25a | 5099 | 0.212 | 0.2801 | Yes |
| 67 | Nop56 | 5199 | 0.207 | 0.2793 | Yes |
| 68 | Nup205 | 5373 | 0.197 | 0.2747 | Yes |
| 69 | Eif2s1 | 5428 | 0.195 | 0.2759 | Yes |
| 70 | Cdc20 | 5472 | 0.192 | 0.2777 | Yes |
| 71 | Cdkn1b | 5687 | 0.187 | 0.2708 | Yes |
| 72 | Gspt1 | 5689 | 0.186 | 0.2745 | Yes |
| 73 | Tubb5 | 5693 | 0.186 | 0.2782 | Yes |
| 74 | Pold3 | 5722 | 0.184 | 0.2806 | Yes |
| 75 | Tk1 | 5732 | 0.184 | 0.2839 | Yes |
| 76 | Bard1 | 5831 | 0.178 | 0.2826 | Yes |
| 77 | Cit | 5833 | 0.178 | 0.2862 | Yes |
| 78 | Msh2 | 5880 | 0.177 | 0.2875 | Yes |
| 79 | Ctcf | 5900 | 0.175 | 0.2901 | Yes |
| 80 | Mcm6 | 6138 | 0.166 | 0.2816 | No |
| 81 | Nap1l1 | 6232 | 0.161 | 0.2802 | No |
| 82 | Cdk1 | 6388 | 0.153 | 0.2755 | No |
| 83 | Ilf3 | 6551 | 0.147 | 0.2704 | No |
| 84 | Tbrg4 | 6627 | 0.143 | 0.2695 | No |
| 85 | Lig1 | 6726 | 0.137 | 0.2674 | No |
| 86 | Aurka | 6866 | 0.129 | 0.2630 | No |
| 87 | Slbp | 6886 | 0.128 | 0.2647 | No |
| 88 | Psip1 | 6923 | 0.127 | 0.2655 | No |
| 89 | Nup107 | 7097 | 0.119 | 0.2592 | No |
| 90 | Nudt21 | 7238 | 0.112 | 0.2544 | No |
| 91 | H2az1 | 7365 | 0.109 | 0.2503 | No |
| 92 | Eed | 7443 | 0.105 | 0.2486 | No |
| 93 | Rbbp7 | 7496 | 0.103 | 0.2481 | No |
| 94 | Brca1 | 7535 | 0.101 | 0.2482 | No |
| 95 | Ccnb2 | 7541 | 0.101 | 0.2500 | No |
| 96 | Pa2g4 | 7593 | 0.098 | 0.2495 | No |
| 97 | Shmt1 | 7653 | 0.096 | 0.2485 | No |
| 98 | Pnn | 7693 | 0.094 | 0.2484 | No |
| 99 | Prkdc | 7899 | 0.088 | 0.2399 | No |
| 100 | Spag5 | 7911 | 0.088 | 0.2411 | No |
| 101 | Hells | 7920 | 0.087 | 0.2425 | No |
| 102 | Stag1 | 8013 | 0.082 | 0.2396 | No |
| 103 | Kif2c | 8082 | 0.080 | 0.2378 | No |
| 104 | Cks1b | 8109 | 0.078 | 0.2381 | No |
| 105 | Spc25 | 8110 | 0.078 | 0.2397 | No |
| 106 | Mthfd2 | 8140 | 0.077 | 0.2398 | No |
| 107 | Usp1 | 8204 | 0.075 | 0.2382 | No |
| 108 | Smc6 | 8456 | 0.063 | 0.2268 | No |
| 109 | Hmga1b | 8807 | 0.048 | 0.2101 | No |
| 110 | Tfrc | 8908 | 0.044 | 0.2060 | No |
| 111 | Gins3 | 8986 | 0.041 | 0.2029 | No |
| 112 | Kif18b | 9007 | 0.039 | 0.2027 | No |
| 113 | Cdkn3 | 9031 | 0.039 | 0.2024 | No |
| 114 | Mcm7 | 9038 | 0.038 | 0.2029 | No |
| 115 | H2ax | 9059 | 0.038 | 0.2026 | No |
| 116 | Srsf2 | 9350 | 0.025 | 0.1885 | No |
| 117 | Timeless | 9370 | 0.024 | 0.1881 | No |
| 118 | Snrpb | 9403 | 0.023 | 0.1869 | No |
| 119 | Chek2 | 9425 | 0.021 | 0.1863 | No |
| 120 | Tra2b | 9426 | 0.021 | 0.1867 | No |
| 121 | Nup153 | 9451 | 0.020 | 0.1859 | No |
| 122 | Suv39h1 | 9680 | 0.010 | 0.1746 | No |
| 123 | Smc4 | 10013 | -0.003 | 0.1579 | No |
| 124 | Paics | 10036 | -0.004 | 0.1569 | No |
| 125 | Dctpp1 | 10091 | -0.006 | 0.1543 | No |
| 126 | Ranbp1 | 10353 | -0.017 | 0.1415 | No |
| 127 | Dek | 10357 | -0.017 | 0.1417 | No |
| 128 | Kif22 | 10547 | -0.025 | 0.1327 | No |
| 129 | Wee1 | 10897 | -0.039 | 0.1159 | No |
| 130 | Pop7 | 10903 | -0.039 | 0.1164 | No |
| 131 | Ezh2 | 11050 | -0.045 | 0.1100 | No |
| 132 | Tubg1 | 11144 | -0.049 | 0.1063 | No |
| 133 | Rpa1 | 11163 | -0.050 | 0.1064 | No |
| 134 | Prim2 | 11304 | -0.057 | 0.1005 | No |
| 135 | Nme1 | 11437 | -0.063 | 0.0952 | No |
| 136 | Ube2s | 11608 | -0.072 | 0.0881 | No |
| 137 | Pole4 | 11616 | -0.072 | 0.0892 | No |
| 138 | Rad50 | 11645 | -0.073 | 0.0893 | No |
| 139 | Ube2t | 11735 | -0.077 | 0.0864 | No |
| 140 | E2f8 | 11790 | -0.080 | 0.0853 | No |
| 141 | Prps1 | 12019 | -0.091 | 0.0757 | No |
| 142 | Cnot9 | 12027 | -0.092 | 0.0772 | No |
| 143 | Chek1 | 12036 | -0.092 | 0.0787 | No |
| 144 | Dut | 12231 | -0.101 | 0.0710 | No |
| 145 | Pold1 | 12299 | -0.104 | 0.0697 | No |
| 146 | Pan2 | 12637 | -0.116 | 0.0551 | No |
| 147 | Nbn | 12692 | -0.118 | 0.0548 | No |
| 148 | Myc | 12714 | -0.119 | 0.0562 | No |
| 149 | Pds5b | 12746 | -0.120 | 0.0571 | No |
| 150 | Wdr90 | 12865 | -0.125 | 0.0538 | No |
| 151 | Ran | 12934 | -0.129 | 0.0530 | No |
| 152 | Diaph3 | 13039 | -0.134 | 0.0505 | No |
| 153 | Asf1b | 13214 | -0.142 | 0.0446 | No |
| 154 | Pms2 | 13292 | -0.145 | 0.0437 | No |
| 155 | Ubr7 | 13312 | -0.146 | 0.0458 | No |
| 156 | Mms22l | 13543 | -0.157 | 0.0374 | No |
| 157 | Tipin | 13549 | -0.158 | 0.0404 | No |
| 158 | Brca2 | 13804 | -0.171 | 0.0311 | No |
| 159 | Psmc3ip | 14173 | -0.189 | 0.0164 | No |
| 160 | Cdk4 | 14186 | -0.190 | 0.0197 | No |
| 161 | Donson | 14300 | -0.195 | 0.0180 | No |
| 162 | Pttg1 | 14471 | -0.203 | 0.0136 | No |
| 163 | Brms1l | 14663 | -0.213 | 0.0083 | No |
| 164 | Cdkn1a | 14725 | -0.216 | 0.0097 | No |
| 165 | Rad51c | 14754 | -0.217 | 0.0127 | No |
| 166 | Luc7l3 | 14840 | -0.222 | 0.0130 | No |
| 167 | Pold2 | 14843 | -0.222 | 0.0175 | No |
| 168 | Ppm1d | 14984 | -0.228 | 0.0151 | No |
| 169 | Rnaseh2a | 15030 | -0.231 | 0.0175 | No |
| 170 | Cdca3 | 15292 | -0.241 | 0.0093 | No |
| 171 | Exosc8 | 15356 | -0.244 | 0.0112 | No |
| 172 | Rad51ap1 | 15420 | -0.247 | 0.0131 | No |
| 173 | Spc24 | 15535 | -0.253 | 0.0125 | No |
| 174 | Mlh1 | 15615 | -0.258 | 0.0138 | No |
| 175 | Trip13 | 15830 | -0.270 | 0.0086 | No |
| 176 | Hus1 | 16165 | -0.288 | -0.0024 | No |
| 177 | Gins1 | 16371 | -0.301 | -0.0065 | No |
| 178 | Hmgb3 | 16994 | -0.337 | -0.0310 | No |
| 179 | Orc2 | 17045 | -0.341 | -0.0265 | No |
| 180 | Pole | 17083 | -0.344 | -0.0214 | No |
| 181 | Ing3 | 17444 | -0.368 | -0.0320 | No |
| 182 | Rad1 | 17458 | -0.370 | -0.0250 | No |
| 183 | Pola2 | 17572 | -0.380 | -0.0229 | No |
| 184 | Asf1a | 17640 | -0.385 | -0.0184 | No |
| 185 | Dclre1b | 17825 | -0.404 | -0.0194 | No |
| 186 | Trp53 | 17850 | -0.406 | -0.0123 | No |
| 187 | Dscc1 | 17943 | -0.412 | -0.0085 | No |
| 188 | Rpa2 | 18208 | -0.437 | -0.0128 | No |
| 189 | Rfc2 | 18342 | -0.450 | -0.0103 | No |
| 190 | Tcf19 | 18432 | -0.459 | -0.0054 | No |
| 191 | Orc6 | 18584 | -0.477 | -0.0032 | No |
| 192 | Rpa3 | 18700 | -0.487 | 0.0010 | No |
| 193 | Cenpm | 18830 | -0.504 | 0.0048 | No |
| 194 | Gins4 | 19089 | -0.544 | 0.0030 | No |
| 195 | Rfc3 | 19573 | -0.657 | -0.0079 | No |
| 196 | Prdx4 | 19600 | -0.666 | 0.0044 | No |
| 197 | Stmn1 | 19880 | -0.828 | 0.0074 | No |

