| Dataset | GMP.GMP.neu_Pheno.cls #Group2_versus_Group3.GMP.neu_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.42316735 |
| Normalized Enrichment Score (NES) | 1.4664242 |
| Nominal p-value | 0.1336117 |
| FDR q-value | 0.1672161 |
| FWER p-Value | 0.484 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ssr1 | 36 | 0.871 | 0.0167 | Yes |
| 2 | Hspa9 | 88 | 0.771 | 0.0305 | Yes |
| 3 | Hsp90b1 | 94 | 0.763 | 0.0464 | Yes |
| 4 | Canx | 104 | 0.746 | 0.0618 | Yes |
| 5 | Hspa4 | 166 | 0.682 | 0.0732 | Yes |
| 6 | Edem1 | 175 | 0.676 | 0.0871 | Yes |
| 7 | Asns | 242 | 0.646 | 0.0975 | Yes |
| 8 | Abcf2 | 286 | 0.627 | 0.1087 | Yes |
| 9 | Rab1a | 309 | 0.615 | 0.1206 | Yes |
| 10 | Psmc4 | 389 | 0.587 | 0.1291 | Yes |
| 11 | Hspa5 | 395 | 0.586 | 0.1413 | Yes |
| 12 | Bhlhe40 | 482 | 0.565 | 0.1489 | Yes |
| 13 | Rpn1 | 531 | 0.551 | 0.1582 | Yes |
| 14 | Tmem97 | 553 | 0.545 | 0.1687 | Yes |
| 15 | Rrm2 | 623 | 0.526 | 0.1764 | Yes |
| 16 | P4ha1 | 640 | 0.523 | 0.1867 | Yes |
| 17 | Got1 | 726 | 0.505 | 0.1931 | Yes |
| 18 | Calr | 741 | 0.503 | 0.2031 | Yes |
| 19 | Stip1 | 762 | 0.498 | 0.2127 | Yes |
| 20 | Actr2 | 799 | 0.492 | 0.2213 | Yes |
| 21 | Acsl3 | 822 | 0.489 | 0.2306 | Yes |
| 22 | Serp1 | 863 | 0.485 | 0.2388 | Yes |
| 23 | Xbp1 | 883 | 0.482 | 0.2481 | Yes |
| 24 | Hspe1 | 950 | 0.472 | 0.2548 | Yes |
| 25 | Tfrc | 953 | 0.472 | 0.2647 | Yes |
| 26 | Ddx39a | 1031 | 0.461 | 0.2706 | Yes |
| 27 | Ero1a | 1099 | 0.452 | 0.2768 | Yes |
| 28 | Hspd1 | 1302 | 0.427 | 0.2757 | Yes |
| 29 | Bub1 | 1394 | 0.416 | 0.2800 | Yes |
| 30 | Prdx1 | 1432 | 0.412 | 0.2868 | Yes |
| 31 | Atp2a2 | 1587 | 0.400 | 0.2876 | Yes |
| 32 | Ufm1 | 1686 | 0.391 | 0.2909 | Yes |
| 33 | Cth | 1790 | 0.382 | 0.2938 | Yes |
| 34 | Slc7a11 | 1981 | 0.368 | 0.2921 | Yes |
| 35 | Ube2d3 | 2006 | 0.366 | 0.2986 | Yes |
| 36 | Mcm2 | 2008 | 0.366 | 0.3063 | Yes |
| 37 | Psmd14 | 2025 | 0.363 | 0.3132 | Yes |
| 38 | Gpi1 | 2104 | 0.357 | 0.3169 | Yes |
| 39 | Uso1 | 2106 | 0.357 | 0.3244 | Yes |
| 40 | Psma3 | 2177 | 0.351 | 0.3283 | Yes |
| 41 | Ykt6 | 2253 | 0.345 | 0.3319 | Yes |
| 42 | Gtf2h1 | 2327 | 0.339 | 0.3354 | Yes |
| 43 | Fgl2 | 2374 | 0.335 | 0.3402 | Yes |
| 44 | Ifrd1 | 2439 | 0.329 | 0.3439 | Yes |
| 45 | Aldoa | 2442 | 0.329 | 0.3508 | Yes |
| 46 | Cdc25a | 2542 | 0.321 | 0.3527 | Yes |
| 47 | Cct6a | 2549 | 0.321 | 0.3592 | Yes |
| 48 | Cfp | 2773 | 0.306 | 0.3544 | Yes |
| 49 | Etf1 | 2809 | 0.304 | 0.3591 | Yes |
| 50 | Txnrd1 | 2882 | 0.298 | 0.3618 | Yes |
| 51 | Elovl5 | 2897 | 0.297 | 0.3674 | Yes |
| 52 | Acly | 2928 | 0.296 | 0.3722 | Yes |
| 53 | Sec11a | 2938 | 0.295 | 0.3780 | Yes |
| 54 | Nup205 | 3220 | 0.279 | 0.3697 | Yes |
| 55 | Cacybp | 3222 | 0.279 | 0.3756 | Yes |
| 56 | Gla | 3599 | 0.258 | 0.3621 | Yes |
| 57 | Pno1 | 3601 | 0.258 | 0.3676 | Yes |
| 58 | Mcm4 | 3608 | 0.258 | 0.3727 | Yes |
| 59 | Psme3 | 3640 | 0.256 | 0.3766 | Yes |
| 60 | Fads1 | 3645 | 0.256 | 0.3818 | Yes |
| 61 | Aurka | 3648 | 0.256 | 0.3872 | Yes |
| 62 | M6pr | 3711 | 0.253 | 0.3894 | Yes |
| 63 | Me1 | 3721 | 0.252 | 0.3943 | Yes |
| 64 | Ung | 3853 | 0.244 | 0.3929 | Yes |
| 65 | Pnp | 3858 | 0.244 | 0.3979 | Yes |
| 66 | Skap2 | 3925 | 0.241 | 0.3996 | Yes |
| 67 | Sqle | 4310 | 0.220 | 0.3849 | Yes |
| 68 | Idh1 | 4465 | 0.212 | 0.3817 | Yes |
| 69 | Acaca | 4475 | 0.212 | 0.3857 | Yes |
| 70 | Psat1 | 4561 | 0.208 | 0.3859 | Yes |
| 71 | Nufip1 | 4588 | 0.206 | 0.3889 | Yes |
| 72 | Map2k3 | 4677 | 0.201 | 0.3887 | Yes |
| 73 | Ppa1 | 4716 | 0.198 | 0.3910 | Yes |
| 74 | Uchl5 | 4739 | 0.197 | 0.3941 | Yes |
| 75 | Immt | 4861 | 0.191 | 0.3921 | Yes |
| 76 | Ccnf | 5045 | 0.185 | 0.3868 | Yes |
| 77 | Slc6a6 | 5048 | 0.185 | 0.3906 | Yes |
| 78 | Psmc6 | 5070 | 0.184 | 0.3934 | Yes |
| 79 | Gmps | 5128 | 0.181 | 0.3944 | Yes |
| 80 | Psmg1 | 5145 | 0.180 | 0.3974 | Yes |
| 81 | Plk1 | 5152 | 0.180 | 0.4009 | Yes |
| 82 | Lgmn | 5160 | 0.179 | 0.4044 | Yes |
| 83 | Actr3 | 5233 | 0.176 | 0.4045 | Yes |
| 84 | Tcea1 | 5305 | 0.173 | 0.4046 | Yes |
| 85 | Sqstm1 | 5411 | 0.168 | 0.4028 | Yes |
| 86 | Hmgcs1 | 5427 | 0.167 | 0.4056 | Yes |
| 87 | Tpi1 | 5439 | 0.166 | 0.4086 | Yes |
| 88 | Ddit4 | 5473 | 0.164 | 0.4104 | Yes |
| 89 | Dhcr7 | 5476 | 0.164 | 0.4138 | Yes |
| 90 | Gsk3b | 5508 | 0.163 | 0.4157 | Yes |
| 91 | Wars1 | 5512 | 0.162 | 0.4190 | Yes |
| 92 | Cdkn1a | 5553 | 0.161 | 0.4204 | Yes |
| 93 | Nmt1 | 5566 | 0.160 | 0.4232 | Yes |
| 94 | Tbk1 | 5878 | 0.146 | 0.4106 | No |
| 95 | Tm7sf2 | 5905 | 0.145 | 0.4123 | No |
| 96 | Slc7a5 | 6026 | 0.139 | 0.4093 | No |
| 97 | G6pdx | 6293 | 0.128 | 0.3986 | No |
| 98 | Sla | 6297 | 0.128 | 0.4011 | No |
| 99 | Ifi30 | 6357 | 0.125 | 0.4008 | No |
| 100 | Ppia | 6560 | 0.118 | 0.3931 | No |
| 101 | Rpa1 | 6567 | 0.117 | 0.3953 | No |
| 102 | Cyb5b | 6936 | 0.103 | 0.3790 | No |
| 103 | Fdxr | 7084 | 0.097 | 0.3736 | No |
| 104 | Nfyc | 7328 | 0.087 | 0.3632 | No |
| 105 | Srd5a1 | 7563 | 0.076 | 0.3530 | No |
| 106 | Pitpnb | 7581 | 0.075 | 0.3537 | No |
| 107 | Psmd12 | 7615 | 0.073 | 0.3536 | No |
| 108 | Dhcr24 | 7669 | 0.071 | 0.3525 | No |
| 109 | Gga2 | 7694 | 0.070 | 0.3527 | No |
| 110 | Slc1a4 | 7706 | 0.069 | 0.3536 | No |
| 111 | Rit1 | 7717 | 0.069 | 0.3546 | No |
| 112 | Idi1 | 7805 | 0.066 | 0.3516 | No |
| 113 | Pgk1 | 7995 | 0.058 | 0.3433 | No |
| 114 | Shmt2 | 8154 | 0.051 | 0.3364 | No |
| 115 | Ldlr | 8219 | 0.048 | 0.3342 | No |
| 116 | Fads2 | 8223 | 0.047 | 0.3351 | No |
| 117 | Eif2s2 | 8278 | 0.045 | 0.3333 | No |
| 118 | Atp6v1d | 8390 | 0.040 | 0.3285 | No |
| 119 | Cyp51 | 8414 | 0.039 | 0.3282 | No |
| 120 | Mthfd2 | 8574 | 0.032 | 0.3209 | No |
| 121 | Stard4 | 8613 | 0.030 | 0.3196 | No |
| 122 | Sdf2l1 | 8666 | 0.028 | 0.3176 | No |
| 123 | Tomm40 | 8672 | 0.028 | 0.3179 | No |
| 124 | Nfil3 | 8897 | 0.017 | 0.3070 | No |
| 125 | Insig1 | 9078 | 0.009 | 0.2981 | No |
| 126 | Psmc2 | 9114 | 0.007 | 0.2965 | No |
| 127 | Gsr | 9190 | 0.004 | 0.2928 | No |
| 128 | Ldha | 9285 | 0.000 | 0.2881 | No |
| 129 | Cops5 | 9355 | -0.001 | 0.2846 | No |
| 130 | Ak4 | 9393 | -0.003 | 0.2828 | No |
| 131 | Pdap1 | 9412 | -0.003 | 0.2820 | No |
| 132 | Pfkl | 9597 | -0.012 | 0.2730 | No |
| 133 | Ccng1 | 9667 | -0.015 | 0.2698 | No |
| 134 | Adipor2 | 9704 | -0.017 | 0.2684 | No |
| 135 | Tes | 9714 | -0.018 | 0.2683 | No |
| 136 | Gbe1 | 9826 | -0.022 | 0.2632 | No |
| 137 | Fkbp2 | 9892 | -0.023 | 0.2604 | No |
| 138 | Qdpr | 10532 | -0.051 | 0.2293 | No |
| 139 | Nfkbib | 10539 | -0.052 | 0.2301 | No |
| 140 | Coro1a | 10670 | -0.056 | 0.2247 | No |
| 141 | Gclc | 10918 | -0.067 | 0.2137 | No |
| 142 | Sytl2 | 10936 | -0.068 | 0.2143 | No |
| 143 | Pdk1 | 10981 | -0.070 | 0.2135 | No |
| 144 | Slc37a4 | 11086 | -0.072 | 0.2098 | No |
| 145 | Sord | 11109 | -0.073 | 0.2103 | No |
| 146 | Nampt | 11136 | -0.074 | 0.2105 | No |
| 147 | Bcat1 | 11271 | -0.080 | 0.2055 | No |
| 148 | Btg2 | 11381 | -0.085 | 0.2018 | No |
| 149 | Hmgcr | 11442 | -0.087 | 0.2006 | No |
| 150 | Slc1a5 | 11445 | -0.087 | 0.2023 | No |
| 151 | Elovl6 | 11449 | -0.088 | 0.2041 | No |
| 152 | Polr3g | 11529 | -0.091 | 0.2020 | No |
| 153 | Rrp9 | 11626 | -0.095 | 0.1992 | No |
| 154 | Psmd13 | 11920 | -0.108 | 0.1867 | No |
| 155 | Hmbs | 11930 | -0.109 | 0.1886 | No |
| 156 | Nupr1 | 12112 | -0.117 | 0.1819 | No |
| 157 | Lta4h | 12330 | -0.125 | 0.1736 | No |
| 158 | Mllt11 | 12342 | -0.126 | 0.1758 | No |
| 159 | Hk2 | 12519 | -0.136 | 0.1698 | No |
| 160 | Pgm1 | 12638 | -0.141 | 0.1668 | No |
| 161 | Add3 | 12911 | -0.153 | 0.1563 | No |
| 162 | Psma4 | 13029 | -0.158 | 0.1538 | No |
| 163 | Mthfd2l | 13092 | -0.160 | 0.1541 | No |
| 164 | Dhfr | 13274 | -0.168 | 0.1485 | No |
| 165 | Slc2a1 | 13459 | -0.178 | 0.1430 | No |
| 166 | Arpc5l | 13479 | -0.179 | 0.1458 | No |
| 167 | Eef1e1 | 14217 | -0.213 | 0.1132 | No |
| 168 | Trib3 | 14357 | -0.221 | 0.1109 | No |
| 169 | Phgdh | 14546 | -0.230 | 0.1063 | No |
| 170 | Ppp1r15a | 14617 | -0.233 | 0.1077 | No |
| 171 | Rdh11 | 14714 | -0.238 | 0.1080 | No |
| 172 | Sc5d | 15014 | -0.253 | 0.0982 | No |
| 173 | Psph | 15204 | -0.262 | 0.0943 | No |
| 174 | Ctsc | 15313 | -0.267 | 0.0945 | No |
| 175 | Eno1b | 15521 | -0.279 | 0.0900 | No |
| 176 | Vldlr | 15624 | -0.285 | 0.0909 | No |
| 177 | Niban1 | 15739 | -0.291 | 0.0913 | No |
| 178 | Ebp | 15945 | -0.303 | 0.0874 | No |
| 179 | Tubg1 | 16085 | -0.312 | 0.0870 | No |
| 180 | Cd9 | 16206 | -0.318 | 0.0877 | No |
| 181 | Glrx | 16429 | -0.329 | 0.0835 | No |
| 182 | Pik3r3 | 17319 | -0.386 | 0.0469 | No |
| 183 | Plod2 | 17535 | -0.402 | 0.0446 | No |
| 184 | Cxcr4 | 17610 | -0.407 | 0.0495 | No |
| 185 | Itgb2 | 17635 | -0.410 | 0.0569 | No |
| 186 | Egln3 | 17656 | -0.412 | 0.0647 | No |
| 187 | Tuba4a | 17770 | -0.423 | 0.0680 | No |
| 188 | Dapp1 | 17779 | -0.424 | 0.0766 | No |
| 189 | Ddit3 | 18849 | -0.539 | 0.0341 | No |
| 190 | Psmb5 | 19060 | -0.571 | 0.0356 | No |
| 191 | Slc2a3 | 19280 | -0.613 | 0.0376 | No |

