| Dataset | GMP.GMP.neu_Pheno.cls #Group2_versus_Group3.GMP.neu_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.4448873 |
| Normalized Enrichment Score (NES) | 1.8355536 |
| Nominal p-value | 0.004048583 |
| FDR q-value | 0.016020494 |
| FWER p-Value | 0.035 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hspa8 | 15 | 1.001 | 0.0206 | Yes |
| 2 | Srsf1 | 45 | 0.858 | 0.0374 | Yes |
| 3 | Kpnb1 | 276 | 0.632 | 0.0392 | Yes |
| 4 | Nek2 | 307 | 0.616 | 0.0509 | Yes |
| 5 | H2bc12 | 339 | 0.605 | 0.0622 | Yes |
| 6 | Sap30 | 390 | 0.586 | 0.0722 | Yes |
| 7 | Racgap1 | 424 | 0.579 | 0.0829 | Yes |
| 8 | Rad54l | 426 | 0.578 | 0.0951 | Yes |
| 9 | Bcl3 | 499 | 0.561 | 0.1035 | Yes |
| 10 | Cenpe | 601 | 0.532 | 0.1097 | Yes |
| 11 | Cks2 | 622 | 0.526 | 0.1199 | Yes |
| 12 | Hnrnpu | 662 | 0.517 | 0.1290 | Yes |
| 13 | Odc1 | 680 | 0.514 | 0.1391 | Yes |
| 14 | Cdc7 | 716 | 0.508 | 0.1481 | Yes |
| 15 | Xpo1 | 888 | 0.482 | 0.1498 | Yes |
| 16 | Upf1 | 889 | 0.481 | 0.1600 | Yes |
| 17 | Jpt1 | 898 | 0.479 | 0.1698 | Yes |
| 18 | Lbr | 919 | 0.477 | 0.1790 | Yes |
| 19 | Cdkn1b | 951 | 0.472 | 0.1875 | Yes |
| 20 | Hmmr | 1011 | 0.463 | 0.1944 | Yes |
| 21 | Ddx39a | 1031 | 0.461 | 0.2032 | Yes |
| 22 | Plk4 | 1208 | 0.439 | 0.2037 | Yes |
| 23 | Ncl | 1230 | 0.436 | 0.2119 | Yes |
| 24 | Nolc1 | 1286 | 0.429 | 0.2183 | Yes |
| 25 | Rad21 | 1306 | 0.426 | 0.2264 | Yes |
| 26 | Dr1 | 1373 | 0.419 | 0.2320 | Yes |
| 27 | Bub1 | 1394 | 0.416 | 0.2399 | Yes |
| 28 | Incenp | 1406 | 0.415 | 0.2482 | Yes |
| 29 | Kif4 | 1453 | 0.411 | 0.2546 | Yes |
| 30 | Cdc6 | 1495 | 0.407 | 0.2612 | Yes |
| 31 | Lig3 | 1525 | 0.405 | 0.2684 | Yes |
| 32 | Syncrip | 1554 | 0.402 | 0.2755 | Yes |
| 33 | G3bp1 | 1669 | 0.393 | 0.2782 | Yes |
| 34 | Mki67 | 1779 | 0.383 | 0.2808 | Yes |
| 35 | Ttk | 1854 | 0.377 | 0.2851 | Yes |
| 36 | Sfpq | 1942 | 0.371 | 0.2886 | Yes |
| 37 | Mcm2 | 2008 | 0.366 | 0.2931 | Yes |
| 38 | E2f4 | 2142 | 0.353 | 0.2940 | Yes |
| 39 | Top2a | 2252 | 0.345 | 0.2958 | Yes |
| 40 | Mcm3 | 2333 | 0.339 | 0.2990 | Yes |
| 41 | Lmnb1 | 2341 | 0.338 | 0.3058 | Yes |
| 42 | Kif11 | 2401 | 0.333 | 0.3100 | Yes |
| 43 | Tpx2 | 2411 | 0.332 | 0.3166 | Yes |
| 44 | Chaf1a | 2417 | 0.331 | 0.3234 | Yes |
| 45 | Nasp | 2531 | 0.322 | 0.3246 | Yes |
| 46 | Cdc25a | 2542 | 0.321 | 0.3309 | Yes |
| 47 | Kif15 | 2564 | 0.320 | 0.3367 | Yes |
| 48 | Ccnt1 | 2584 | 0.319 | 0.3425 | Yes |
| 49 | Amd1 | 2657 | 0.314 | 0.3456 | Yes |
| 50 | Kif5b | 2785 | 0.305 | 0.3457 | Yes |
| 51 | E2f2 | 2840 | 0.302 | 0.3494 | Yes |
| 52 | Casp8ap2 | 2912 | 0.296 | 0.3521 | Yes |
| 53 | Cdkn2c | 2967 | 0.294 | 0.3557 | Yes |
| 54 | Nsd2 | 2970 | 0.294 | 0.3618 | Yes |
| 55 | Tnpo2 | 3016 | 0.291 | 0.3658 | Yes |
| 56 | Hnrnpd | 3038 | 0.290 | 0.3709 | Yes |
| 57 | Birc5 | 3173 | 0.281 | 0.3701 | Yes |
| 58 | Ndc80 | 3227 | 0.278 | 0.3734 | Yes |
| 59 | Kif20b | 3294 | 0.274 | 0.3759 | Yes |
| 60 | Notch2 | 3637 | 0.256 | 0.3641 | Yes |
| 61 | Aurka | 3648 | 0.256 | 0.3690 | Yes |
| 62 | Nup98 | 3755 | 0.249 | 0.3690 | Yes |
| 63 | Dbf4 | 3772 | 0.248 | 0.3735 | Yes |
| 64 | Smc1a | 3774 | 0.248 | 0.3787 | Yes |
| 65 | Cenpf | 3787 | 0.248 | 0.3834 | Yes |
| 66 | Prmt5 | 3790 | 0.248 | 0.3886 | Yes |
| 67 | Gspt1 | 3794 | 0.247 | 0.3937 | Yes |
| 68 | Prc1 | 3839 | 0.245 | 0.3967 | Yes |
| 69 | Tent4a | 3848 | 0.245 | 0.4015 | Yes |
| 70 | Kif23 | 4022 | 0.237 | 0.3978 | Yes |
| 71 | Pttg1 | 4024 | 0.236 | 0.4028 | Yes |
| 72 | Tra2b | 4068 | 0.234 | 0.4057 | Yes |
| 73 | Ube2s | 4136 | 0.230 | 0.4072 | Yes |
| 74 | Slc38a1 | 4183 | 0.227 | 0.4097 | Yes |
| 75 | Kif22 | 4193 | 0.227 | 0.4141 | Yes |
| 76 | Mcm5 | 4249 | 0.224 | 0.4161 | Yes |
| 77 | Ythdc1 | 4255 | 0.224 | 0.4206 | Yes |
| 78 | Sqle | 4310 | 0.220 | 0.4226 | Yes |
| 79 | Hira | 4353 | 0.218 | 0.4251 | Yes |
| 80 | Cul1 | 4360 | 0.218 | 0.4294 | Yes |
| 81 | Tfdp1 | 4556 | 0.208 | 0.4240 | Yes |
| 82 | Troap | 4597 | 0.206 | 0.4264 | Yes |
| 83 | Uck2 | 4619 | 0.205 | 0.4297 | Yes |
| 84 | E2f3 | 4650 | 0.203 | 0.4325 | Yes |
| 85 | Rad23b | 4731 | 0.197 | 0.4327 | Yes |
| 86 | Pafah1b1 | 4737 | 0.197 | 0.4366 | Yes |
| 87 | Ccnf | 5045 | 0.185 | 0.4251 | Yes |
| 88 | Numa1 | 5122 | 0.181 | 0.4251 | Yes |
| 89 | Plk1 | 5152 | 0.180 | 0.4275 | Yes |
| 90 | Abl1 | 5180 | 0.178 | 0.4299 | Yes |
| 91 | Mtf2 | 5187 | 0.178 | 0.4334 | Yes |
| 92 | Cdk1 | 5228 | 0.176 | 0.4352 | Yes |
| 93 | Top1 | 5239 | 0.175 | 0.4384 | Yes |
| 94 | Wrn | 5250 | 0.175 | 0.4416 | Yes |
| 95 | Atrx | 5295 | 0.173 | 0.4431 | Yes |
| 96 | Cdc27 | 5333 | 0.172 | 0.4449 | Yes |
| 97 | H2az1 | 5558 | 0.161 | 0.4370 | No |
| 98 | Ilf3 | 5611 | 0.158 | 0.4378 | No |
| 99 | Stag1 | 5654 | 0.156 | 0.4390 | No |
| 100 | Odf2 | 5737 | 0.152 | 0.4381 | No |
| 101 | Mybl2 | 5816 | 0.149 | 0.4373 | No |
| 102 | Chmp1a | 5872 | 0.146 | 0.4377 | No |
| 103 | Rbl1 | 5969 | 0.142 | 0.4359 | No |
| 104 | Slc7a5 | 6026 | 0.139 | 0.4360 | No |
| 105 | Smc2 | 6039 | 0.139 | 0.4383 | No |
| 106 | Kif2c | 6060 | 0.137 | 0.4403 | No |
| 107 | Smarcc1 | 6130 | 0.135 | 0.4397 | No |
| 108 | Ss18 | 6330 | 0.126 | 0.4323 | No |
| 109 | Tmpo | 6374 | 0.124 | 0.4328 | No |
| 110 | Hif1a | 6376 | 0.124 | 0.4354 | No |
| 111 | Bard1 | 6573 | 0.117 | 0.4280 | No |
| 112 | Tacc3 | 6619 | 0.115 | 0.4282 | No |
| 113 | Mcm6 | 6709 | 0.112 | 0.4261 | No |
| 114 | Prpf4b | 6713 | 0.112 | 0.4283 | No |
| 115 | Ccna2 | 6738 | 0.110 | 0.4295 | No |
| 116 | Chek1 | 6865 | 0.106 | 0.4254 | No |
| 117 | Stil | 6873 | 0.106 | 0.4273 | No |
| 118 | Polq | 6986 | 0.101 | 0.4238 | No |
| 119 | Arid4a | 7008 | 0.100 | 0.4249 | No |
| 120 | Kmt5a | 7047 | 0.098 | 0.4250 | No |
| 121 | Pbk | 7063 | 0.098 | 0.4264 | No |
| 122 | Suv39h1 | 7300 | 0.088 | 0.4163 | No |
| 123 | Snrpd1 | 7334 | 0.087 | 0.4165 | No |
| 124 | Smad3 | 7555 | 0.076 | 0.4071 | No |
| 125 | Espl1 | 8018 | 0.057 | 0.3850 | No |
| 126 | Atf5 | 8116 | 0.053 | 0.3812 | No |
| 127 | Cul3 | 8340 | 0.042 | 0.3708 | No |
| 128 | Exo1 | 8426 | 0.039 | 0.3674 | No |
| 129 | Gins2 | 8465 | 0.038 | 0.3663 | No |
| 130 | Cenpa | 8555 | 0.033 | 0.3625 | No |
| 131 | Aurkb | 8650 | 0.028 | 0.3584 | No |
| 132 | Cks1b | 8660 | 0.028 | 0.3585 | No |
| 133 | Orc5 | 8734 | 0.025 | 0.3554 | No |
| 134 | Fancc | 8837 | 0.020 | 0.3506 | No |
| 135 | Slc7a1 | 8937 | 0.015 | 0.3460 | No |
| 136 | Rpa2 | 9066 | 0.010 | 0.3397 | No |
| 137 | Tle3 | 9291 | 0.000 | 0.3285 | No |
| 138 | Smc4 | 9397 | -0.003 | 0.3232 | No |
| 139 | Cul5 | 9407 | -0.003 | 0.3228 | No |
| 140 | Cdc45 | 9445 | -0.005 | 0.3211 | No |
| 141 | Ctcf | 9665 | -0.015 | 0.3104 | No |
| 142 | Map3k20 | 9790 | -0.021 | 0.3045 | No |
| 143 | Ewsr1 | 9821 | -0.022 | 0.3035 | No |
| 144 | Cul4a | 9885 | -0.023 | 0.3008 | No |
| 145 | Dkc1 | 9956 | -0.026 | 0.2978 | No |
| 146 | Srsf10 | 10011 | -0.029 | 0.2957 | No |
| 147 | Bub3 | 10190 | -0.037 | 0.2875 | No |
| 148 | Knl1 | 10262 | -0.040 | 0.2848 | No |
| 149 | Srsf2 | 10410 | -0.047 | 0.2784 | No |
| 150 | Pura | 10434 | -0.047 | 0.2782 | No |
| 151 | Prim2 | 10436 | -0.047 | 0.2792 | No |
| 152 | Cdc25b | 10686 | -0.057 | 0.2679 | No |
| 153 | Ube2c | 10781 | -0.061 | 0.2644 | No |
| 154 | Mapk14 | 10785 | -0.061 | 0.2656 | No |
| 155 | Hmgb3 | 10857 | -0.064 | 0.2634 | No |
| 156 | Foxn3 | 10860 | -0.065 | 0.2647 | No |
| 157 | Pds5b | 11026 | -0.071 | 0.2579 | No |
| 158 | Ccnb2 | 11121 | -0.074 | 0.2547 | No |
| 159 | Traip | 11190 | -0.077 | 0.2529 | No |
| 160 | Hus1 | 11218 | -0.078 | 0.2532 | No |
| 161 | Brca2 | 11313 | -0.082 | 0.2502 | No |
| 162 | Efna5 | 11689 | -0.098 | 0.2334 | No |
| 163 | Slc12a2 | 11703 | -0.099 | 0.2348 | No |
| 164 | Ezh2 | 12048 | -0.114 | 0.2199 | No |
| 165 | Fbxo5 | 12052 | -0.115 | 0.2222 | No |
| 166 | Pml | 12212 | -0.120 | 0.2167 | No |
| 167 | Pola2 | 12311 | -0.124 | 0.2144 | No |
| 168 | Rps6ka5 | 12462 | -0.132 | 0.2097 | No |
| 169 | Meis1 | 12567 | -0.138 | 0.2074 | No |
| 170 | Nusap1 | 12710 | -0.144 | 0.2033 | No |
| 171 | Mnat1 | 12714 | -0.144 | 0.2062 | No |
| 172 | Cdc20 | 12882 | -0.152 | 0.2010 | No |
| 173 | Orc6 | 12973 | -0.156 | 0.1998 | No |
| 174 | Hmga1b | 13194 | -0.165 | 0.1922 | No |
| 175 | Nup50 | 13222 | -0.166 | 0.1944 | No |
| 176 | Pole | 13251 | -0.167 | 0.1966 | No |
| 177 | Tgfb1 | 13944 | -0.199 | 0.1659 | No |
| 178 | Mad2l1 | 13956 | -0.200 | 0.1696 | No |
| 179 | Rasal2 | 14299 | -0.218 | 0.1570 | No |
| 180 | E2f1 | 14569 | -0.230 | 0.1483 | No |
| 181 | Katna1 | 14588 | -0.231 | 0.1524 | No |
| 182 | Dmd | 15238 | -0.264 | 0.1253 | No |
| 183 | Cbx1 | 15306 | -0.266 | 0.1276 | No |
| 184 | Dtymk | 15637 | -0.285 | 0.1170 | No |
| 185 | H2ax | 15768 | -0.293 | 0.1167 | No |
| 186 | Meis2 | 15937 | -0.303 | 0.1147 | No |
| 187 | Cdk4 | 16515 | -0.333 | 0.0927 | No |
| 188 | H2az2 | 17058 | -0.368 | 0.0732 | No |
| 189 | Myc | 17216 | -0.379 | 0.0733 | No |
| 190 | Egf | 17727 | -0.419 | 0.0565 | No |
| 191 | Cdkn3 | 18595 | -0.503 | 0.0235 | No |
| 192 | Marcks | 19032 | -0.566 | 0.0136 | No |
| 193 | Stmn1 | 19564 | -0.687 | 0.0015 | No |
| 194 | Ccnd1 | 19976 | -1.022 | 0.0025 | No |

