| Dataset | GMP.GMP.neu_Pheno.cls #Group2_versus_Group3.GMP.neu_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.38024002 |
| Normalized Enrichment Score (NES) | 1.6047722 |
| Nominal p-value | 0.06485356 |
| FDR q-value | 0.080741346 |
| FWER p-Value | 0.253 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccne1 | 23 | 0.926 | 0.0181 | Yes |
| 2 | Srsf1 | 45 | 0.858 | 0.0348 | Yes |
| 3 | Dck | 167 | 0.682 | 0.0429 | Yes |
| 4 | Ccp110 | 177 | 0.675 | 0.0564 | Yes |
| 5 | Zw10 | 188 | 0.672 | 0.0699 | Yes |
| 6 | Dnmt1 | 216 | 0.657 | 0.0821 | Yes |
| 7 | Racgap1 | 424 | 0.579 | 0.0837 | Yes |
| 8 | Bub1b | 454 | 0.572 | 0.0941 | Yes |
| 9 | Cdca8 | 564 | 0.542 | 0.0999 | Yes |
| 10 | Cenpe | 601 | 0.532 | 0.1091 | Yes |
| 11 | Cks2 | 622 | 0.526 | 0.1190 | Yes |
| 12 | Rrm2 | 623 | 0.526 | 0.1299 | Yes |
| 13 | Ipo7 | 632 | 0.524 | 0.1404 | Yes |
| 14 | Xpo1 | 888 | 0.482 | 0.1376 | Yes |
| 15 | Jpt1 | 898 | 0.479 | 0.1471 | Yes |
| 16 | Lbr | 919 | 0.477 | 0.1559 | Yes |
| 17 | Cdkn1b | 951 | 0.472 | 0.1642 | Yes |
| 18 | Tfrc | 953 | 0.472 | 0.1739 | Yes |
| 19 | Hmmr | 1011 | 0.463 | 0.1807 | Yes |
| 20 | Ddx39a | 1031 | 0.461 | 0.1893 | Yes |
| 21 | Ran | 1086 | 0.453 | 0.1960 | Yes |
| 22 | Hells | 1194 | 0.441 | 0.1997 | Yes |
| 23 | Plk4 | 1208 | 0.439 | 0.2082 | Yes |
| 24 | Nolc1 | 1286 | 0.429 | 0.2132 | Yes |
| 25 | Rad21 | 1306 | 0.426 | 0.2211 | Yes |
| 26 | Lsm8 | 1308 | 0.426 | 0.2299 | Yes |
| 27 | Smc3 | 1431 | 0.413 | 0.2323 | Yes |
| 28 | Kif4 | 1453 | 0.411 | 0.2398 | Yes |
| 29 | Syncrip | 1554 | 0.402 | 0.2431 | Yes |
| 30 | Anp32e | 1622 | 0.396 | 0.2479 | Yes |
| 31 | Mki67 | 1779 | 0.383 | 0.2480 | Yes |
| 32 | Cbx5 | 1953 | 0.370 | 0.2469 | Yes |
| 33 | Mcm2 | 2008 | 0.366 | 0.2518 | Yes |
| 34 | Cit | 2111 | 0.357 | 0.2541 | Yes |
| 35 | Rad51ap1 | 2144 | 0.353 | 0.2598 | Yes |
| 36 | Top2a | 2252 | 0.345 | 0.2615 | Yes |
| 37 | Mcm3 | 2333 | 0.339 | 0.2645 | Yes |
| 38 | Hmgb2 | 2336 | 0.339 | 0.2715 | Yes |
| 39 | Lmnb1 | 2341 | 0.338 | 0.2783 | Yes |
| 40 | Lyar | 2352 | 0.338 | 0.2848 | Yes |
| 41 | Nasp | 2531 | 0.322 | 0.2825 | Yes |
| 42 | Ak2 | 2536 | 0.322 | 0.2890 | Yes |
| 43 | Cdc25a | 2542 | 0.321 | 0.2954 | Yes |
| 44 | Phf5a | 2609 | 0.317 | 0.2987 | Yes |
| 45 | Cse1l | 2777 | 0.306 | 0.2966 | Yes |
| 46 | Ppp1r8 | 2913 | 0.296 | 0.2959 | Yes |
| 47 | Tbrg4 | 2920 | 0.296 | 0.3018 | Yes |
| 48 | Atad2 | 2933 | 0.295 | 0.3073 | Yes |
| 49 | Cdkn2c | 2967 | 0.294 | 0.3117 | Yes |
| 50 | Mre11a | 2977 | 0.293 | 0.3174 | Yes |
| 51 | Hnrnpd | 3038 | 0.290 | 0.3204 | Yes |
| 52 | Pcna | 3131 | 0.284 | 0.3216 | Yes |
| 53 | Usp1 | 3150 | 0.282 | 0.3265 | Yes |
| 54 | Birc5 | 3173 | 0.281 | 0.3313 | Yes |
| 55 | Nup107 | 3175 | 0.281 | 0.3370 | Yes |
| 56 | Nup205 | 3220 | 0.279 | 0.3406 | Yes |
| 57 | Pnn | 3325 | 0.273 | 0.3410 | Yes |
| 58 | Brca1 | 3338 | 0.272 | 0.3461 | Yes |
| 59 | Nudt21 | 3361 | 0.271 | 0.3506 | Yes |
| 60 | Mcm4 | 3608 | 0.258 | 0.3435 | Yes |
| 61 | Ssrp1 | 3620 | 0.257 | 0.3483 | Yes |
| 62 | Aurka | 3648 | 0.256 | 0.3523 | Yes |
| 63 | Smc1a | 3774 | 0.248 | 0.3511 | Yes |
| 64 | Gspt1 | 3794 | 0.247 | 0.3553 | Yes |
| 65 | Ung | 3853 | 0.244 | 0.3574 | Yes |
| 66 | Pttg1 | 4024 | 0.236 | 0.3538 | Yes |
| 67 | Tra2b | 4068 | 0.234 | 0.3565 | Yes |
| 68 | Ube2s | 4136 | 0.230 | 0.3579 | Yes |
| 69 | Spc25 | 4150 | 0.229 | 0.3620 | Yes |
| 70 | Prkdc | 4168 | 0.228 | 0.3658 | Yes |
| 71 | Kif22 | 4193 | 0.227 | 0.3693 | Yes |
| 72 | Ncapd2 | 4200 | 0.226 | 0.3737 | Yes |
| 73 | Mcm5 | 4249 | 0.224 | 0.3760 | Yes |
| 74 | Eif2s1 | 4257 | 0.224 | 0.3802 | Yes |
| 75 | Dut | 4438 | 0.214 | 0.3756 | No |
| 76 | Gins1 | 4640 | 0.203 | 0.3697 | No |
| 77 | Plk1 | 5152 | 0.180 | 0.3476 | No |
| 78 | Cdk1 | 5228 | 0.176 | 0.3475 | No |
| 79 | Tk1 | 5469 | 0.164 | 0.3388 | No |
| 80 | Cdkn1a | 5553 | 0.161 | 0.3380 | No |
| 81 | H2az1 | 5558 | 0.161 | 0.3411 | No |
| 82 | Ilf3 | 5611 | 0.158 | 0.3418 | No |
| 83 | Stag1 | 5654 | 0.156 | 0.3429 | No |
| 84 | Shmt1 | 5708 | 0.153 | 0.3434 | No |
| 85 | Nup153 | 5760 | 0.151 | 0.3440 | No |
| 86 | Psip1 | 5780 | 0.150 | 0.3461 | No |
| 87 | Mybl2 | 5816 | 0.149 | 0.3474 | No |
| 88 | Pold3 | 5970 | 0.142 | 0.3427 | No |
| 89 | Chek2 | 6029 | 0.139 | 0.3426 | No |
| 90 | Kif2c | 6060 | 0.137 | 0.3440 | No |
| 91 | Gins3 | 6133 | 0.134 | 0.3431 | No |
| 92 | Nap1l1 | 6262 | 0.129 | 0.3394 | No |
| 93 | Tmpo | 6374 | 0.124 | 0.3363 | No |
| 94 | Pa2g4 | 6383 | 0.124 | 0.3385 | No |
| 95 | Nbn | 6459 | 0.121 | 0.3372 | No |
| 96 | Pop7 | 6526 | 0.120 | 0.3364 | No |
| 97 | Rpa1 | 6567 | 0.117 | 0.3368 | No |
| 98 | E2f8 | 6570 | 0.117 | 0.3391 | No |
| 99 | Bard1 | 6573 | 0.117 | 0.3415 | No |
| 100 | Tacc3 | 6619 | 0.115 | 0.3416 | No |
| 101 | Rbbp7 | 6636 | 0.115 | 0.3432 | No |
| 102 | Xrcc6 | 6682 | 0.113 | 0.3433 | No |
| 103 | Mcm6 | 6709 | 0.112 | 0.3443 | No |
| 104 | Psmc3ip | 6799 | 0.109 | 0.3420 | No |
| 105 | Lig1 | 6813 | 0.108 | 0.3436 | No |
| 106 | Chek1 | 6865 | 0.106 | 0.3433 | No |
| 107 | Slbp | 7028 | 0.099 | 0.3372 | No |
| 108 | Dlgap5 | 7104 | 0.095 | 0.3354 | No |
| 109 | Donson | 7268 | 0.089 | 0.3290 | No |
| 110 | Suv39h1 | 7300 | 0.088 | 0.3293 | No |
| 111 | Rfc1 | 7435 | 0.082 | 0.3242 | No |
| 112 | Nop56 | 7447 | 0.081 | 0.3253 | No |
| 113 | Smc6 | 7497 | 0.079 | 0.3245 | No |
| 114 | Ubr7 | 7750 | 0.068 | 0.3132 | No |
| 115 | Espl1 | 8018 | 0.057 | 0.3009 | No |
| 116 | Exosc8 | 8149 | 0.051 | 0.2954 | No |
| 117 | Wee1 | 8242 | 0.047 | 0.2918 | No |
| 118 | Eed | 8308 | 0.043 | 0.2894 | No |
| 119 | Mthfd2 | 8574 | 0.032 | 0.2767 | No |
| 120 | Aurkb | 8650 | 0.028 | 0.2735 | No |
| 121 | Cks1b | 8660 | 0.028 | 0.2736 | No |
| 122 | Rad50 | 8683 | 0.027 | 0.2731 | No |
| 123 | Trip13 | 8696 | 0.026 | 0.2730 | No |
| 124 | Tubb5 | 9040 | 0.011 | 0.2559 | No |
| 125 | Rpa2 | 9066 | 0.010 | 0.2549 | No |
| 126 | Msh2 | 9213 | 0.003 | 0.2476 | No |
| 127 | Melk | 9237 | 0.002 | 0.2465 | No |
| 128 | Cdca3 | 9265 | 0.001 | 0.2451 | No |
| 129 | Smc4 | 9397 | -0.003 | 0.2386 | No |
| 130 | Mxd3 | 9477 | -0.007 | 0.2347 | No |
| 131 | Dek | 9495 | -0.008 | 0.2340 | No |
| 132 | Ctcf | 9665 | -0.015 | 0.2258 | No |
| 133 | Paics | 9749 | -0.019 | 0.2220 | No |
| 134 | Pms2 | 9811 | -0.021 | 0.2194 | No |
| 135 | Mlh1 | 9958 | -0.026 | 0.2126 | No |
| 136 | Mcm7 | 9998 | -0.028 | 0.2112 | No |
| 137 | Prps1 | 10269 | -0.041 | 0.1984 | No |
| 138 | Pan2 | 10279 | -0.041 | 0.1988 | No |
| 139 | Srsf2 | 10410 | -0.047 | 0.1932 | No |
| 140 | Prim2 | 10436 | -0.047 | 0.1930 | No |
| 141 | Mms22l | 10498 | -0.050 | 0.1909 | No |
| 142 | Cdc25b | 10686 | -0.057 | 0.1827 | No |
| 143 | Nme1 | 10710 | -0.058 | 0.1827 | No |
| 144 | Hmgb3 | 10857 | -0.064 | 0.1767 | No |
| 145 | Ranbp1 | 10964 | -0.069 | 0.1728 | No |
| 146 | Pds5b | 11026 | -0.071 | 0.1712 | No |
| 147 | Ccnb2 | 11121 | -0.074 | 0.1680 | No |
| 148 | Hus1 | 11218 | -0.078 | 0.1648 | No |
| 149 | Brca2 | 11313 | -0.082 | 0.1617 | No |
| 150 | Orc2 | 11437 | -0.087 | 0.1573 | No |
| 151 | Spag5 | 11497 | -0.090 | 0.1562 | No |
| 152 | Dctpp1 | 11523 | -0.090 | 0.1568 | No |
| 153 | Cnot9 | 11602 | -0.094 | 0.1548 | No |
| 154 | Ezh2 | 12048 | -0.114 | 0.1348 | No |
| 155 | Rad51c | 12061 | -0.115 | 0.1366 | No |
| 156 | Luc7l3 | 12072 | -0.116 | 0.1384 | No |
| 157 | Prdx4 | 12102 | -0.117 | 0.1394 | No |
| 158 | Brms1l | 12139 | -0.118 | 0.1401 | No |
| 159 | Pola2 | 12311 | -0.124 | 0.1340 | No |
| 160 | Diaph3 | 12315 | -0.124 | 0.1364 | No |
| 161 | Depdc1a | 12470 | -0.132 | 0.1314 | No |
| 162 | Tipin | 12851 | -0.150 | 0.1154 | No |
| 163 | Cdc20 | 12882 | -0.152 | 0.1170 | No |
| 164 | Orc6 | 12973 | -0.156 | 0.1157 | No |
| 165 | Hmga1b | 13194 | -0.165 | 0.1080 | No |
| 166 | Pole | 13251 | -0.167 | 0.1087 | No |
| 167 | Ube2t | 13356 | -0.173 | 0.1070 | No |
| 168 | Rfc3 | 13390 | -0.174 | 0.1090 | No |
| 169 | Dclre1b | 13471 | -0.178 | 0.1086 | No |
| 170 | Snrpb | 13524 | -0.181 | 0.1098 | No |
| 171 | Mad2l1 | 13956 | -0.200 | 0.0922 | No |
| 172 | Timeless | 14365 | -0.222 | 0.0762 | No |
| 173 | Gins4 | 14634 | -0.234 | 0.0675 | No |
| 174 | Pold2 | 14647 | -0.235 | 0.0718 | No |
| 175 | Pold1 | 14653 | -0.235 | 0.0765 | No |
| 176 | Kif18b | 15220 | -0.262 | 0.0534 | No |
| 177 | Ppm1d | 15315 | -0.267 | 0.0542 | No |
| 178 | Trp53 | 15601 | -0.283 | 0.0457 | No |
| 179 | Wdr90 | 15611 | -0.284 | 0.0511 | No |
| 180 | H2ax | 15768 | -0.293 | 0.0493 | No |
| 181 | Pole4 | 15888 | -0.300 | 0.0495 | No |
| 182 | Tubg1 | 16085 | -0.312 | 0.0461 | No |
| 183 | Tcf19 | 16106 | -0.313 | 0.0516 | No |
| 184 | Rpa3 | 16302 | -0.323 | 0.0485 | No |
| 185 | Cdk4 | 16515 | -0.333 | 0.0447 | No |
| 186 | Asf1a | 17119 | -0.371 | 0.0220 | No |
| 187 | Myc | 17216 | -0.379 | 0.0250 | No |
| 188 | Asf1b | 17397 | -0.391 | 0.0241 | No |
| 189 | Spc24 | 18344 | -0.476 | -0.0138 | No |
| 190 | Rad1 | 18439 | -0.487 | -0.0084 | No |
| 191 | Cdkn3 | 18595 | -0.503 | -0.0058 | No |
| 192 | Rfc2 | 18770 | -0.527 | -0.0036 | No |
| 193 | Ing3 | 19039 | -0.567 | -0.0054 | No |
| 194 | Dscc1 | 19161 | -0.589 | 0.0008 | No |
| 195 | Rnaseh2a | 19198 | -0.596 | 0.0113 | No |
| 196 | Stmn1 | 19564 | -0.687 | 0.0072 | No |
| 197 | Cenpm | 19744 | -0.774 | 0.0142 | No |

