Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	GMP.GMP.neu_Pheno.cls #Group1_versus_Group4.GMP.neu_Pheno.cls #Group1_versus_Group4_repos
Phenotype	GMP.neu_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.18535395
Normalized Enrichment Score (NES)	-1.0047024
Nominal p-value	0.46361747
FDR q-value	0.706786
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Adcy2	161	0.829	0.0314	No
2	Egfr	713	0.588	0.0318	No
3	Traf2	1217	0.500	0.0304	No
4	Cltc	1541	0.447	0.0355	No
5	Akt1	1556	0.445	0.0560	No
6	Pten	1941	0.410	0.0563	No
7	Myd88	2068	0.398	0.0689	No
8	Actr2	2519	0.362	0.0636	No
9	Prkcb	3444	0.292	0.0312	No
10	Atf1	3536	0.286	0.0402	No
11	Ralb	3813	0.271	0.0393	No
12	Them4	4336	0.242	0.0246	No
13	Cdk1	4350	0.241	0.0354	No
14	Akt1s1	4716	0.224	0.0277	No
15	Pin1	4923	0.220	0.0279	No
16	Cab39	4980	0.216	0.0353	No
17	Smad2	4985	0.215	0.0454	No
18	Itpr2	5068	0.211	0.0513	No
19	Ppp2r1b	5198	0.203	0.0545	No
20	Tsc2	5336	0.195	0.0569	No
21	Sfn	5740	0.173	0.0450	No
22	Plcg1	5880	0.166	0.0459	No
23	Hsp90b1	6022	0.159	0.0464	No
24	Ptpn11	6330	0.150	0.0381	No
25	Actr3	6409	0.147	0.0412	No
26	Raf1	6480	0.145	0.0446	No
27	Rps6ka1	6637	0.137	0.0433	No
28	Pla2g12a	6659	0.136	0.0488	No
29	Ap2m1	6752	0.131	0.0504	No
30	Tiam1	6808	0.128	0.0537	No
31	Tnfrsf1a	6864	0.127	0.0570	No
32	Grb2	7055	0.118	0.0531	No
33	Calr	7212	0.112	0.0506	No
34	Arf1	7415	0.103	0.0454	No
35	Hras	7461	0.101	0.0480	No
36	Prkar2a	7466	0.101	0.0526	No
37	Mapk8	7556	0.098	0.0528	No
38	Rptor	7561	0.098	0.0572	No
39	Pikfyve	7746	0.088	0.0522	No
40	Ywhab	7971	0.079	0.0447	No
41	Mknk2	8081	0.075	0.0428	No
42	Eif4e	8335	0.064	0.0332	No
43	Slc2a1	8455	0.059	0.0300	No
44	Mapk1	8517	0.056	0.0296	No
45	Mapkap1	8779	0.046	0.0187	No
46	Map2k3	9039	0.036	0.0074	No
47	Trib3	9328	0.024	-0.0059	No
48	Mapk9	9946	0.002	-0.0367	No
49	Pak4	10191	-0.001	-0.0489	No
50	Pdk1	10624	-0.018	-0.0697	No
51	Grk2	10647	-0.019	-0.0699	No
52	Map3k7	10683	-0.020	-0.0707	No
53	Vav3	10863	-0.026	-0.0785	No
54	Irak4	10900	-0.027	-0.0790	No
55	Gsk3b	11257	-0.043	-0.0948	No
56	Arpc3	11444	-0.050	-0.1017	No
57	Ripk1	11715	-0.061	-0.1124	No
58	Nck1	11852	-0.067	-0.1160	No
59	Mknk1	11977	-0.071	-0.1189	No
60	Map2k6	12640	-0.099	-0.1474	No
61	Nod1	12776	-0.104	-0.1492	No
62	Camk4	12834	-0.106	-0.1470	No
63	Lck	12912	-0.109	-0.1457	No
64	Sla	13133	-0.116	-0.1512	No
65	Nfkbib	13194	-0.118	-0.1486	No
66	Ube2d3	13258	-0.121	-0.1460	No
67	Gna14	13547	-0.131	-0.1542	No
68	Sqstm1	13713	-0.138	-0.1559	No
69	Acaca	14038	-0.153	-0.1648	No
70	Prkag1	14339	-0.166	-0.1720	No
71	Fgf22	14607	-0.179	-0.1768	Yes
72	Rac1	14656	-0.181	-0.1706	Yes
73	Csnk2b	14823	-0.189	-0.1699	Yes
74	Pfn1	14996	-0.199	-0.1691	Yes
75	Mapk10	15291	-0.211	-0.1738	Yes
76	Ube2n	15362	-0.212	-0.1672	Yes
77	Plcb1	15424	-0.216	-0.1599	Yes
78	Dusp3	15579	-0.222	-0.1571	Yes
79	Rps6ka3	15596	-0.222	-0.1473	Yes
80	E2f1	15992	-0.243	-0.1555	Yes
81	Arhgdia	16207	-0.257	-0.1540	Yes
82	Tbk1	16241	-0.259	-0.1433	Yes
83	Stat2	16256	-0.260	-0.1317	Yes
84	Cab39l	16313	-0.264	-0.1219	Yes
85	Cdk2	16642	-0.279	-0.1251	Yes
86	Cdkn1b	16691	-0.283	-0.1140	Yes
87	Cdk4	16993	-0.301	-0.1148	Yes
88	Rit1	17224	-0.313	-0.1114	Yes
89	Prkaa2	17303	-0.317	-0.1002	Yes
90	Ppp1ca	17787	-0.351	-0.1077	Yes
91	Il4	18061	-0.372	-0.1037	Yes
92	Cxcr4	18324	-0.396	-0.0980	Yes
93	Ecsit	18526	-0.412	-0.0884	Yes
94	Pik3r3	18684	-0.427	-0.0760	Yes
95	Il2rg	19358	-0.537	-0.0841	Yes
96	Ddit3	19416	-0.550	-0.0608	Yes
97	Cfl1	19462	-0.563	-0.0362	Yes
98	Cdkn1a	19559	-0.586	-0.0131	Yes
99	Dapp1	19900	-0.766	0.0063	Yes