| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group4.GMP.neu_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_P53_PATHWAY |
| Enrichment Score (ES) | -0.26221654 |
| Normalized Enrichment Score (NES) | -1.1237478 |
| Nominal p-value | 0.2776618 |
| FDR q-value | 0.96207565 |
| FWER p-Value | 0.961 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tchh | 115 | 0.899 | 0.0155 | No |
| 2 | Klf4 | 201 | 0.806 | 0.0304 | No |
| 3 | H2ac25 | 269 | 0.770 | 0.0452 | No |
| 4 | Stom | 666 | 0.597 | 0.0394 | No |
| 5 | Jun | 723 | 0.587 | 0.0505 | No |
| 6 | Ldhb | 944 | 0.536 | 0.0521 | No |
| 7 | Jag2 | 985 | 0.526 | 0.0626 | No |
| 8 | Ada | 1054 | 0.517 | 0.0714 | No |
| 9 | Dcxr | 1952 | 0.408 | 0.0359 | No |
| 10 | Cdh13 | 2333 | 0.377 | 0.0257 | No |
| 11 | Itgb4 | 2363 | 0.373 | 0.0331 | No |
| 12 | Alox8 | 2411 | 0.370 | 0.0395 | No |
| 13 | Cd82 | 2529 | 0.361 | 0.0421 | No |
| 14 | Aen | 2530 | 0.361 | 0.0507 | No |
| 15 | Abcc5 | 2639 | 0.352 | 0.0536 | No |
| 16 | Txnip | 3094 | 0.320 | 0.0383 | No |
| 17 | Btg2 | 3254 | 0.306 | 0.0376 | No |
| 18 | Sdc1 | 3349 | 0.299 | 0.0399 | No |
| 19 | Rgs16 | 3354 | 0.298 | 0.0468 | No |
| 20 | Ralgds | 3363 | 0.298 | 0.0535 | No |
| 21 | Vdr | 3776 | 0.273 | 0.0392 | No |
| 22 | Foxo3 | 3816 | 0.270 | 0.0436 | No |
| 23 | Rab40c | 3853 | 0.268 | 0.0482 | No |
| 24 | Hmox1 | 3950 | 0.265 | 0.0496 | No |
| 25 | Ppp1r15a | 3971 | 0.264 | 0.0549 | No |
| 26 | Mdm2 | 3978 | 0.263 | 0.0608 | No |
| 27 | Cyfip2 | 4162 | 0.253 | 0.0576 | No |
| 28 | Nudt15 | 4294 | 0.245 | 0.0568 | No |
| 29 | Rrp8 | 4357 | 0.240 | 0.0593 | No |
| 30 | Cd81 | 4888 | 0.221 | 0.0379 | No |
| 31 | Pmm1 | 5230 | 0.200 | 0.0254 | No |
| 32 | Trafd1 | 5238 | 0.200 | 0.0298 | No |
| 33 | Rrad | 5257 | 0.199 | 0.0336 | No |
| 34 | Hspa4l | 5279 | 0.199 | 0.0373 | No |
| 35 | Tap1 | 5342 | 0.195 | 0.0388 | No |
| 36 | F2r | 5669 | 0.177 | 0.0265 | No |
| 37 | Ctsd | 5705 | 0.175 | 0.0289 | No |
| 38 | Sfn | 5740 | 0.173 | 0.0313 | No |
| 39 | Tgfa | 5829 | 0.169 | 0.0309 | No |
| 40 | Ccp110 | 5839 | 0.168 | 0.0344 | No |
| 41 | H1f2 | 5861 | 0.168 | 0.0373 | No |
| 42 | Polh | 6078 | 0.156 | 0.0302 | No |
| 43 | Fam162a | 6401 | 0.148 | 0.0174 | No |
| 44 | Prmt2 | 6584 | 0.140 | 0.0116 | No |
| 45 | Plk2 | 6740 | 0.132 | 0.0069 | No |
| 46 | Def6 | 6916 | 0.125 | 0.0010 | No |
| 47 | Klk8 | 7054 | 0.118 | -0.0031 | No |
| 48 | Abhd4 | 7059 | 0.118 | -0.0005 | No |
| 49 | Slc3a2 | 7213 | 0.112 | -0.0055 | No |
| 50 | Rad9a | 7290 | 0.108 | -0.0068 | No |
| 51 | Hdac3 | 7330 | 0.107 | -0.0062 | No |
| 52 | Fdxr | 7369 | 0.105 | -0.0057 | No |
| 53 | Hras | 7461 | 0.101 | -0.0078 | No |
| 54 | Coq8a | 7504 | 0.100 | -0.0076 | No |
| 55 | Tob1 | 7527 | 0.099 | -0.0064 | No |
| 56 | Elp1 | 7538 | 0.099 | -0.0045 | No |
| 57 | Ifi30 | 7595 | 0.096 | -0.0051 | No |
| 58 | Tpd52l1 | 7618 | 0.095 | -0.0039 | No |
| 59 | Rhbdf2 | 7725 | 0.089 | -0.0072 | No |
| 60 | Wwp1 | 7845 | 0.084 | -0.0112 | No |
| 61 | Prkab1 | 7927 | 0.081 | -0.0133 | No |
| 62 | Fuca1 | 7955 | 0.080 | -0.0128 | No |
| 63 | Hexim1 | 8004 | 0.078 | -0.0134 | No |
| 64 | Mknk2 | 8081 | 0.075 | -0.0154 | No |
| 65 | Ccng1 | 8203 | 0.069 | -0.0199 | No |
| 66 | Sp1 | 8238 | 0.068 | -0.0200 | No |
| 67 | Baiap2 | 8242 | 0.068 | -0.0186 | No |
| 68 | Slc7a11 | 8282 | 0.066 | -0.0189 | No |
| 69 | Tax1bp3 | 8337 | 0.064 | -0.0201 | No |
| 70 | Fbxw7 | 8635 | 0.050 | -0.0339 | No |
| 71 | Fos | 8800 | 0.045 | -0.0411 | No |
| 72 | Ccnd2 | 8888 | 0.043 | -0.0445 | No |
| 73 | Ip6k2 | 8937 | 0.040 | -0.0459 | No |
| 74 | Nupr1 | 9045 | 0.036 | -0.0505 | No |
| 75 | Ercc5 | 9133 | 0.032 | -0.0541 | No |
| 76 | App | 9156 | 0.032 | -0.0545 | No |
| 77 | Xpc | 9161 | 0.031 | -0.0539 | No |
| 78 | Bax | 9274 | 0.026 | -0.0589 | No |
| 79 | Trib3 | 9328 | 0.024 | -0.0610 | No |
| 80 | Slc35d1 | 9370 | 0.023 | -0.0625 | No |
| 81 | Apaf1 | 9545 | 0.017 | -0.0709 | No |
| 82 | Fas | 9736 | 0.010 | -0.0802 | No |
| 83 | Notch1 | 9781 | 0.008 | -0.0823 | No |
| 84 | Osgin1 | 9817 | 0.007 | -0.0839 | No |
| 85 | Zfp36l1 | 9906 | 0.004 | -0.0882 | No |
| 86 | Ddb2 | 10177 | -0.001 | -0.1018 | No |
| 87 | Rps12 | 10441 | -0.011 | -0.1148 | No |
| 88 | Kif13b | 10542 | -0.014 | -0.1195 | No |
| 89 | Rnf19b | 10947 | -0.030 | -0.1392 | No |
| 90 | Rap2b | 10955 | -0.030 | -0.1388 | No |
| 91 | Sphk1 | 10991 | -0.032 | -0.1398 | No |
| 92 | Ier5 | 11094 | -0.036 | -0.1441 | No |
| 93 | Ei24 | 11104 | -0.037 | -0.1437 | No |
| 94 | Triap1 | 11111 | -0.037 | -0.1431 | No |
| 95 | Fgf13 | 11185 | -0.040 | -0.1459 | No |
| 96 | Ccnk | 11277 | -0.044 | -0.1494 | No |
| 97 | Ppm1d | 11473 | -0.051 | -0.1580 | No |
| 98 | Tprkb | 11563 | -0.055 | -0.1612 | No |
| 99 | Pdgfa | 11611 | -0.057 | -0.1622 | No |
| 100 | Mapkapk3 | 11629 | -0.057 | -0.1617 | No |
| 101 | Tm7sf3 | 11682 | -0.059 | -0.1630 | No |
| 102 | Hbegf | 11840 | -0.066 | -0.1693 | No |
| 103 | Abat | 11927 | -0.069 | -0.1720 | No |
| 104 | Mxd4 | 11941 | -0.070 | -0.1710 | No |
| 105 | Pvt1 | 12218 | -0.081 | -0.1830 | No |
| 106 | Irag2 | 12390 | -0.088 | -0.1895 | No |
| 107 | Pcna | 12454 | -0.091 | -0.1905 | No |
| 108 | Pom121 | 12485 | -0.092 | -0.1899 | No |
| 109 | Rb1 | 12775 | -0.104 | -0.2019 | No |
| 110 | Bak1 | 13033 | -0.114 | -0.2122 | No |
| 111 | Socs1 | 13349 | -0.124 | -0.2251 | No |
| 112 | Zbtb16 | 13462 | -0.128 | -0.2277 | No |
| 113 | Perp | 13634 | -0.135 | -0.2331 | No |
| 114 | Cdkn2aip | 13692 | -0.137 | -0.2328 | No |
| 115 | Gadd45a | 13913 | -0.148 | -0.2403 | No |
| 116 | Ddit4 | 14348 | -0.167 | -0.2583 | Yes |
| 117 | Atf3 | 14386 | -0.168 | -0.2561 | Yes |
| 118 | Sesn1 | 14494 | -0.174 | -0.2574 | Yes |
| 119 | Eps8l2 | 14532 | -0.175 | -0.2551 | Yes |
| 120 | Sat1 | 14557 | -0.176 | -0.2521 | Yes |
| 121 | St14 | 14667 | -0.182 | -0.2533 | Yes |
| 122 | Nol8 | 14670 | -0.182 | -0.2491 | Yes |
| 123 | Iscu | 14762 | -0.186 | -0.2493 | Yes |
| 124 | Ninj1 | 14837 | -0.190 | -0.2485 | Yes |
| 125 | Ptpn14 | 14858 | -0.191 | -0.2450 | Yes |
| 126 | Rpl18 | 14975 | -0.198 | -0.2461 | Yes |
| 127 | Retsat | 15007 | -0.199 | -0.2430 | Yes |
| 128 | Rps27l | 15022 | -0.200 | -0.2389 | Yes |
| 129 | Cdk5r1 | 15035 | -0.200 | -0.2348 | Yes |
| 130 | Zmat3 | 15251 | -0.211 | -0.2406 | Yes |
| 131 | S100a4 | 15254 | -0.211 | -0.2357 | Yes |
| 132 | Dnttip2 | 15366 | -0.213 | -0.2363 | Yes |
| 133 | Csrnp2 | 15428 | -0.216 | -0.2342 | Yes |
| 134 | Rack1 | 15576 | -0.222 | -0.2364 | Yes |
| 135 | H2aj | 15651 | -0.225 | -0.2348 | Yes |
| 136 | Rpl36 | 15717 | -0.228 | -0.2326 | Yes |
| 137 | Trp53 | 15777 | -0.230 | -0.2301 | Yes |
| 138 | Dgka | 15781 | -0.231 | -0.2248 | Yes |
| 139 | Ptpre | 15820 | -0.233 | -0.2212 | Yes |
| 140 | Pidd1 | 15924 | -0.238 | -0.2207 | Yes |
| 141 | Tnfsf9 | 16049 | -0.247 | -0.2211 | Yes |
| 142 | S100a10 | 16092 | -0.250 | -0.2173 | Yes |
| 143 | Pitpnc1 | 16119 | -0.251 | -0.2127 | Yes |
| 144 | Rchy1 | 16231 | -0.259 | -0.2122 | Yes |
| 145 | Rxra | 16238 | -0.259 | -0.2063 | Yes |
| 146 | Hint1 | 16245 | -0.259 | -0.2005 | Yes |
| 147 | Tsc22d1 | 16455 | -0.271 | -0.2046 | Yes |
| 148 | Ctsf | 16776 | -0.288 | -0.2139 | Yes |
| 149 | Steap3 | 16813 | -0.289 | -0.2089 | Yes |
| 150 | Mxd1 | 17073 | -0.304 | -0.2147 | Yes |
| 151 | Vwa5a | 17135 | -0.308 | -0.2105 | Yes |
| 152 | Ankra2 | 17296 | -0.317 | -0.2110 | Yes |
| 153 | Btg1 | 17353 | -0.319 | -0.2063 | Yes |
| 154 | Tspyl2 | 17446 | -0.326 | -0.2032 | Yes |
| 155 | Ndrg1 | 17530 | -0.330 | -0.1995 | Yes |
| 156 | Blcap | 17537 | -0.331 | -0.1920 | Yes |
| 157 | Irak1 | 17573 | -0.333 | -0.1859 | Yes |
| 158 | Dram1 | 17780 | -0.350 | -0.1879 | Yes |
| 159 | Tgfb1 | 17835 | -0.355 | -0.1823 | Yes |
| 160 | Casp1 | 18054 | -0.371 | -0.1844 | Yes |
| 161 | Sertad3 | 18093 | -0.375 | -0.1775 | Yes |
| 162 | Rad51c | 18183 | -0.384 | -0.1728 | Yes |
| 163 | Sec61a1 | 18203 | -0.385 | -0.1647 | Yes |
| 164 | Cebpa | 18320 | -0.396 | -0.1611 | Yes |
| 165 | Vamp8 | 18362 | -0.400 | -0.1537 | Yes |
| 166 | Ccnd3 | 18452 | -0.406 | -0.1486 | Yes |
| 167 | Acvr1b | 18709 | -0.430 | -0.1513 | Yes |
| 168 | Wrap73 | 18845 | -0.451 | -0.1474 | Yes |
| 169 | Plxnb2 | 18897 | -0.458 | -0.1391 | Yes |
| 170 | Slc19a2 | 19057 | -0.478 | -0.1358 | Yes |
| 171 | Tcn2 | 19079 | -0.481 | -0.1254 | Yes |
| 172 | Ak1 | 19199 | -0.504 | -0.1195 | Yes |
| 173 | Traf4 | 19311 | -0.528 | -0.1126 | Yes |
| 174 | Plk3 | 19350 | -0.536 | -0.1018 | Yes |
| 175 | Procr | 19391 | -0.543 | -0.0909 | Yes |
| 176 | Ddit3 | 19416 | -0.550 | -0.0791 | Yes |
| 177 | Cgrrf1 | 19438 | -0.558 | -0.0669 | Yes |
| 178 | Gm2a | 19529 | -0.579 | -0.0577 | Yes |
| 179 | Cdkn1a | 19559 | -0.586 | -0.0453 | Yes |
| 180 | Ephx1 | 19571 | -0.589 | -0.0319 | Yes |
| 181 | Ier3 | 19821 | -0.685 | -0.0282 | Yes |
| 182 | Trp63 | 19890 | -0.748 | -0.0139 | Yes |
| 183 | Gls2 | 19969 | -0.873 | 0.0029 | Yes |

