| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group4.GMP.neu_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | 0.19978526 |
| Normalized Enrichment Score (NES) | 0.8346568 |
| Nominal p-value | 0.6046025 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cyp51 | 66 | 1.002 | 0.0197 | Yes |
| 2 | Sqle | 117 | 0.898 | 0.0378 | Yes |
| 3 | Stard4 | 141 | 0.853 | 0.0562 | Yes |
| 4 | Insig1 | 320 | 0.732 | 0.0640 | Yes |
| 5 | Dhcr24 | 327 | 0.729 | 0.0805 | Yes |
| 6 | Cth | 563 | 0.629 | 0.0831 | Yes |
| 7 | Hmgcr | 630 | 0.608 | 0.0937 | Yes |
| 8 | Fgl2 | 714 | 0.588 | 0.1030 | Yes |
| 9 | Ldlr | 747 | 0.582 | 0.1148 | Yes |
| 10 | Gga2 | 1061 | 0.515 | 0.1108 | Yes |
| 11 | Gpi1 | 1187 | 0.506 | 0.1161 | Yes |
| 12 | Pno1 | 1243 | 0.495 | 0.1247 | Yes |
| 13 | Rrp9 | 1299 | 0.485 | 0.1331 | Yes |
| 14 | Idi1 | 1349 | 0.473 | 0.1415 | Yes |
| 15 | Acly | 1378 | 0.469 | 0.1508 | Yes |
| 16 | Plk1 | 1447 | 0.460 | 0.1580 | Yes |
| 17 | Pgk1 | 1740 | 0.427 | 0.1531 | Yes |
| 18 | Aldoa | 2007 | 0.404 | 0.1489 | Yes |
| 19 | Bhlhe40 | 2042 | 0.400 | 0.1564 | Yes |
| 20 | Actr2 | 2519 | 0.362 | 0.1407 | Yes |
| 21 | Hk2 | 2670 | 0.350 | 0.1412 | Yes |
| 22 | Hspd1 | 2683 | 0.348 | 0.1486 | Yes |
| 23 | Stip1 | 2752 | 0.340 | 0.1529 | Yes |
| 24 | Canx | 2905 | 0.334 | 0.1530 | Yes |
| 25 | Tm7sf2 | 2909 | 0.334 | 0.1605 | Yes |
| 26 | Psme3 | 2925 | 0.333 | 0.1673 | Yes |
| 27 | Atp2a2 | 2936 | 0.331 | 0.1744 | Yes |
| 28 | Ddx39a | 3011 | 0.327 | 0.1782 | Yes |
| 29 | Psmc4 | 3083 | 0.321 | 0.1820 | Yes |
| 30 | Etf1 | 3142 | 0.316 | 0.1864 | Yes |
| 31 | Btg2 | 3254 | 0.306 | 0.1878 | Yes |
| 32 | Ak4 | 3272 | 0.304 | 0.1939 | Yes |
| 33 | Hmbs | 3306 | 0.302 | 0.1992 | Yes |
| 34 | Ero1a | 3511 | 0.287 | 0.1955 | Yes |
| 35 | Hspa4 | 3661 | 0.280 | 0.1944 | Yes |
| 36 | Nufip1 | 3756 | 0.274 | 0.1960 | Yes |
| 37 | Hspa9 | 3805 | 0.271 | 0.1998 | Yes |
| 38 | Ppp1r15a | 3971 | 0.264 | 0.1975 | No |
| 39 | Ccnf | 4115 | 0.255 | 0.1962 | No |
| 40 | Edem1 | 4280 | 0.245 | 0.1936 | No |
| 41 | Serp1 | 4399 | 0.237 | 0.1931 | No |
| 42 | Ung | 4414 | 0.236 | 0.1978 | No |
| 43 | Polr3g | 4586 | 0.232 | 0.1945 | No |
| 44 | Elovl5 | 4701 | 0.225 | 0.1939 | No |
| 45 | Eno1b | 4969 | 0.217 | 0.1854 | No |
| 46 | Gsr | 5246 | 0.199 | 0.1761 | No |
| 47 | Mcm4 | 5311 | 0.197 | 0.1774 | No |
| 48 | Glrx | 5313 | 0.197 | 0.1818 | No |
| 49 | Bub1 | 5317 | 0.196 | 0.1862 | No |
| 50 | Pgm1 | 5554 | 0.184 | 0.1785 | No |
| 51 | Rpn1 | 5604 | 0.181 | 0.1802 | No |
| 52 | Cyb5b | 5717 | 0.174 | 0.1786 | No |
| 53 | Xbp1 | 5857 | 0.168 | 0.1754 | No |
| 54 | Ppia | 5996 | 0.160 | 0.1721 | No |
| 55 | Hsp90b1 | 6022 | 0.159 | 0.1745 | No |
| 56 | Cd9 | 6048 | 0.157 | 0.1768 | No |
| 57 | Nfyc | 6380 | 0.148 | 0.1636 | No |
| 58 | Actr3 | 6409 | 0.147 | 0.1655 | No |
| 59 | Psmb5 | 6481 | 0.144 | 0.1653 | No |
| 60 | Cct6a | 6549 | 0.142 | 0.1652 | No |
| 61 | Tpi1 | 6670 | 0.136 | 0.1622 | No |
| 62 | Hspa5 | 6745 | 0.131 | 0.1615 | No |
| 63 | Psat1 | 6754 | 0.131 | 0.1641 | No |
| 64 | Tubg1 | 6794 | 0.129 | 0.1651 | No |
| 65 | M6pr | 6886 | 0.126 | 0.1634 | No |
| 66 | Txnrd1 | 6912 | 0.125 | 0.1650 | No |
| 67 | Itgb2 | 6978 | 0.122 | 0.1645 | No |
| 68 | Calr | 7212 | 0.112 | 0.1554 | No |
| 69 | Ctsc | 7277 | 0.109 | 0.1546 | No |
| 70 | Pfkl | 7285 | 0.109 | 0.1568 | No |
| 71 | Cdc25a | 7305 | 0.108 | 0.1583 | No |
| 72 | Fdxr | 7369 | 0.105 | 0.1575 | No |
| 73 | Rab1a | 7400 | 0.104 | 0.1584 | No |
| 74 | Pnp | 7560 | 0.098 | 0.1526 | No |
| 75 | Ifi30 | 7595 | 0.096 | 0.1531 | No |
| 76 | Lta4h | 7617 | 0.095 | 0.1542 | No |
| 77 | G6pdx | 7636 | 0.094 | 0.1555 | No |
| 78 | Nampt | 7667 | 0.092 | 0.1561 | No |
| 79 | Psmd14 | 8172 | 0.070 | 0.1323 | No |
| 80 | Ccng1 | 8203 | 0.069 | 0.1324 | No |
| 81 | Rpa1 | 8276 | 0.066 | 0.1303 | No |
| 82 | Slc7a11 | 8282 | 0.066 | 0.1315 | No |
| 83 | Add3 | 8298 | 0.065 | 0.1323 | No |
| 84 | Ifrd1 | 8307 | 0.065 | 0.1334 | No |
| 85 | Pitpnb | 8388 | 0.062 | 0.1308 | No |
| 86 | Slc2a1 | 8455 | 0.059 | 0.1288 | No |
| 87 | Prdx1 | 8536 | 0.054 | 0.1260 | No |
| 88 | Ykt6 | 8588 | 0.052 | 0.1246 | No |
| 89 | Atp6v1d | 8595 | 0.052 | 0.1255 | No |
| 90 | Slc37a4 | 8600 | 0.052 | 0.1265 | No |
| 91 | Gbe1 | 8877 | 0.043 | 0.1136 | No |
| 92 | Map2k3 | 9039 | 0.036 | 0.1063 | No |
| 93 | Nupr1 | 9045 | 0.036 | 0.1068 | No |
| 94 | Mcm2 | 9098 | 0.033 | 0.1050 | No |
| 95 | Abcf2 | 9120 | 0.033 | 0.1047 | No |
| 96 | Uchl5 | 9200 | 0.030 | 0.1014 | No |
| 97 | Trib3 | 9328 | 0.024 | 0.0956 | No |
| 98 | Gla | 9346 | 0.024 | 0.0952 | No |
| 99 | Gtf2h1 | 9400 | 0.022 | 0.0931 | No |
| 100 | Wars1 | 9531 | 0.018 | 0.0869 | No |
| 101 | Idh1 | 9783 | 0.008 | 0.0745 | No |
| 102 | Ppa1 | 9876 | 0.005 | 0.0699 | No |
| 103 | Eef1e1 | 9893 | 0.004 | 0.0692 | No |
| 104 | Slc2a3 | 9932 | 0.002 | 0.0674 | No |
| 105 | Rdh11 | 9957 | 0.002 | 0.0662 | No |
| 106 | Nup205 | 10284 | -0.005 | 0.0499 | No |
| 107 | Skap2 | 10506 | -0.013 | 0.0390 | No |
| 108 | Fads1 | 10594 | -0.016 | 0.0350 | No |
| 109 | Pdk1 | 10624 | -0.018 | 0.0340 | No |
| 110 | Mthfd2 | 11019 | -0.033 | 0.0149 | No |
| 111 | Dhcr7 | 11026 | -0.033 | 0.0153 | No |
| 112 | P4ha1 | 11080 | -0.036 | 0.0135 | No |
| 113 | Psmg1 | 11170 | -0.039 | 0.0099 | No |
| 114 | Coro1a | 11227 | -0.042 | 0.0080 | No |
| 115 | Phgdh | 11248 | -0.043 | 0.0080 | No |
| 116 | Gsk3b | 11257 | -0.043 | 0.0086 | No |
| 117 | Sc5d | 11317 | -0.045 | 0.0066 | No |
| 118 | Uso1 | 11330 | -0.046 | 0.0071 | No |
| 119 | Gmps | 11409 | -0.048 | 0.0042 | No |
| 120 | Cacybp | 11617 | -0.057 | -0.0049 | No |
| 121 | Nfil3 | 11684 | -0.059 | -0.0069 | No |
| 122 | Tuba4a | 11827 | -0.066 | -0.0125 | No |
| 123 | Slc6a6 | 12138 | -0.078 | -0.0263 | No |
| 124 | Ssr1 | 12375 | -0.087 | -0.0362 | No |
| 125 | Nmt1 | 12556 | -0.095 | -0.0431 | No |
| 126 | Ufm1 | 12664 | -0.100 | -0.0462 | No |
| 127 | Pdap1 | 12924 | -0.110 | -0.0568 | No |
| 128 | Tmem97 | 12944 | -0.110 | -0.0552 | No |
| 129 | Adipor2 | 12999 | -0.113 | -0.0553 | No |
| 130 | Sla | 13133 | -0.116 | -0.0594 | No |
| 131 | Vldlr | 13180 | -0.118 | -0.0590 | No |
| 132 | Nfkbib | 13194 | -0.118 | -0.0569 | No |
| 133 | Ube2d3 | 13258 | -0.121 | -0.0573 | No |
| 134 | Immt | 13364 | -0.125 | -0.0598 | No |
| 135 | Psmd12 | 13384 | -0.125 | -0.0578 | No |
| 136 | Niban1 | 13561 | -0.132 | -0.0637 | No |
| 137 | Fads2 | 13655 | -0.136 | -0.0653 | No |
| 138 | Aurka | 13694 | -0.138 | -0.0640 | No |
| 139 | Hspe1 | 13705 | -0.138 | -0.0614 | No |
| 140 | Sqstm1 | 13713 | -0.138 | -0.0585 | No |
| 141 | Psmc6 | 13735 | -0.139 | -0.0564 | No |
| 142 | Acaca | 14038 | -0.153 | -0.0681 | No |
| 143 | Psmc2 | 14061 | -0.154 | -0.0657 | No |
| 144 | Slc1a5 | 14121 | -0.157 | -0.0650 | No |
| 145 | Tomm40 | 14132 | -0.157 | -0.0619 | No |
| 146 | Egln3 | 14274 | -0.163 | -0.0653 | No |
| 147 | Hmgcs1 | 14342 | -0.166 | -0.0649 | No |
| 148 | Ddit4 | 14348 | -0.167 | -0.0613 | No |
| 149 | Psmd13 | 14746 | -0.186 | -0.0770 | No |
| 150 | Psma3 | 14848 | -0.191 | -0.0777 | No |
| 151 | Qdpr | 15461 | -0.218 | -0.1036 | No |
| 152 | Sec11a | 15464 | -0.218 | -0.0987 | No |
| 153 | Rrm2 | 15508 | -0.219 | -0.0959 | No |
| 154 | Psma4 | 15526 | -0.219 | -0.0917 | No |
| 155 | Sytl2 | 15733 | -0.229 | -0.0968 | No |
| 156 | Me1 | 15910 | -0.238 | -0.1002 | No |
| 157 | Tbk1 | 16241 | -0.259 | -0.1109 | No |
| 158 | Sord | 16251 | -0.260 | -0.1054 | No |
| 159 | Gclc | 16270 | -0.261 | -0.1003 | No |
| 160 | Bcat1 | 16647 | -0.280 | -0.1129 | No |
| 161 | Elovl6 | 16779 | -0.288 | -0.1129 | No |
| 162 | Ebp | 16786 | -0.288 | -0.1065 | No |
| 163 | Got1 | 17025 | -0.302 | -0.1116 | No |
| 164 | Tcea1 | 17054 | -0.303 | -0.1061 | No |
| 165 | Acsl3 | 17111 | -0.306 | -0.1019 | No |
| 166 | Shmt2 | 17112 | -0.306 | -0.0948 | No |
| 167 | Tfrc | 17154 | -0.309 | -0.0898 | No |
| 168 | Psph | 17157 | -0.309 | -0.0828 | No |
| 169 | Fkbp2 | 17168 | -0.310 | -0.0762 | No |
| 170 | Rit1 | 17224 | -0.313 | -0.0718 | No |
| 171 | Lgmn | 17344 | -0.319 | -0.0704 | No |
| 172 | Cops5 | 17529 | -0.330 | -0.0721 | No |
| 173 | Slc7a5 | 17570 | -0.333 | -0.0665 | No |
| 174 | Mllt11 | 17671 | -0.341 | -0.0637 | No |
| 175 | Tes | 17677 | -0.341 | -0.0562 | No |
| 176 | Mthfd2l | 17678 | -0.341 | -0.0483 | No |
| 177 | Ldha | 18048 | -0.371 | -0.0584 | No |
| 178 | Sdf2l1 | 18246 | -0.389 | -0.0594 | No |
| 179 | Cxcr4 | 18324 | -0.396 | -0.0542 | No |
| 180 | Asns | 18391 | -0.402 | -0.0483 | No |
| 181 | Arpc5l | 18486 | -0.408 | -0.0436 | No |
| 182 | Eif2s2 | 18660 | -0.423 | -0.0426 | No |
| 183 | Pik3r3 | 18684 | -0.427 | -0.0340 | No |
| 184 | Slc1a4 | 18876 | -0.455 | -0.0332 | No |
| 185 | Srd5a1 | 19104 | -0.486 | -0.0335 | No |
| 186 | Plod2 | 19189 | -0.503 | -0.0262 | No |
| 187 | Cfp | 19289 | -0.525 | -0.0191 | No |
| 188 | Dhfr | 19380 | -0.540 | -0.0113 | No |
| 189 | Ddit3 | 19416 | -0.550 | -0.0004 | No |
| 190 | Cdkn1a | 19559 | -0.586 | 0.0059 | No |
| 191 | Dapp1 | 19900 | -0.766 | 0.0064 | No |

