| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group4.GMP.neu_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.18877055 |
| Normalized Enrichment Score (NES) | 0.7813529 |
| Nominal p-value | 0.65652174 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdkn2c | 514 | 0.645 | -0.0094 | Yes |
| 2 | Mxd3 | 709 | 0.588 | -0.0041 | Yes |
| 3 | Dck | 763 | 0.578 | 0.0080 | Yes |
| 4 | Depdc1a | 897 | 0.545 | 0.0152 | Yes |
| 5 | Srsf1 | 934 | 0.537 | 0.0272 | Yes |
| 6 | Xpo1 | 1056 | 0.516 | 0.0343 | Yes |
| 7 | Cse1l | 1384 | 0.468 | 0.0298 | Yes |
| 8 | Plk1 | 1447 | 0.460 | 0.0384 | Yes |
| 9 | Ncapd2 | 1519 | 0.450 | 0.0463 | Yes |
| 10 | Lmnb1 | 1596 | 0.439 | 0.0538 | Yes |
| 11 | Ipo7 | 1716 | 0.429 | 0.0587 | Yes |
| 12 | Rad21 | 1843 | 0.419 | 0.0631 | Yes |
| 13 | Cdc25b | 2001 | 0.405 | 0.0656 | Yes |
| 14 | Hnrnpd | 2015 | 0.403 | 0.0752 | Yes |
| 15 | Espl1 | 2067 | 0.398 | 0.0828 | Yes |
| 16 | Bub1b | 2183 | 0.389 | 0.0870 | Yes |
| 17 | Aurkb | 2316 | 0.379 | 0.0900 | Yes |
| 18 | Dlgap5 | 2776 | 0.338 | 0.0755 | Yes |
| 19 | Smc1a | 2894 | 0.336 | 0.0782 | Yes |
| 20 | Atad2 | 2897 | 0.335 | 0.0867 | Yes |
| 21 | Shmt1 | 2907 | 0.334 | 0.0948 | Yes |
| 22 | Melk | 2945 | 0.330 | 0.1014 | Yes |
| 23 | Top2a | 3005 | 0.328 | 0.1068 | Yes |
| 24 | Ddx39a | 3011 | 0.327 | 0.1149 | Yes |
| 25 | Syncrip | 3088 | 0.321 | 0.1193 | Yes |
| 26 | Rbbp7 | 3286 | 0.303 | 0.1171 | Yes |
| 27 | Kif18b | 3410 | 0.295 | 0.1185 | Yes |
| 28 | Cdc20 | 3474 | 0.291 | 0.1227 | Yes |
| 29 | Phf5a | 3498 | 0.288 | 0.1289 | Yes |
| 30 | Mybl2 | 3578 | 0.283 | 0.1322 | Yes |
| 31 | Anp32e | 3698 | 0.277 | 0.1333 | Yes |
| 32 | Kif2c | 3997 | 0.263 | 0.1250 | Yes |
| 33 | Lbr | 4077 | 0.258 | 0.1276 | Yes |
| 34 | Dnmt1 | 4149 | 0.253 | 0.1305 | Yes |
| 35 | Mcm5 | 4349 | 0.241 | 0.1266 | Yes |
| 36 | Cdk1 | 4350 | 0.241 | 0.1328 | Yes |
| 37 | Birc5 | 4409 | 0.236 | 0.1359 | Yes |
| 38 | Ung | 4414 | 0.236 | 0.1418 | Yes |
| 39 | Nop56 | 4605 | 0.231 | 0.1381 | Yes |
| 40 | Smc3 | 4702 | 0.225 | 0.1390 | Yes |
| 41 | Jpt1 | 4779 | 0.223 | 0.1409 | Yes |
| 42 | Cdca8 | 4780 | 0.223 | 0.1466 | Yes |
| 43 | Timeless | 4929 | 0.219 | 0.1447 | Yes |
| 44 | Msh2 | 4930 | 0.219 | 0.1504 | Yes |
| 45 | Cbx5 | 5024 | 0.213 | 0.1511 | Yes |
| 46 | Hmmr | 5049 | 0.212 | 0.1553 | Yes |
| 47 | Xrcc6 | 5132 | 0.206 | 0.1565 | Yes |
| 48 | Ilf3 | 5161 | 0.205 | 0.1603 | Yes |
| 49 | Cdkn3 | 5252 | 0.199 | 0.1609 | Yes |
| 50 | Mcm4 | 5311 | 0.197 | 0.1630 | Yes |
| 51 | Rnaseh2a | 5361 | 0.194 | 0.1654 | Yes |
| 52 | Spag5 | 5376 | 0.193 | 0.1697 | Yes |
| 53 | Prkdc | 5539 | 0.184 | 0.1662 | Yes |
| 54 | Tacc3 | 5645 | 0.178 | 0.1655 | Yes |
| 55 | Mad2l1 | 5657 | 0.177 | 0.1695 | Yes |
| 56 | Cenpe | 5744 | 0.173 | 0.1696 | Yes |
| 57 | Plk4 | 5751 | 0.173 | 0.1737 | Yes |
| 58 | Ctcf | 5765 | 0.172 | 0.1775 | Yes |
| 59 | Ube2t | 5804 | 0.170 | 0.1799 | Yes |
| 60 | Ccp110 | 5839 | 0.168 | 0.1825 | Yes |
| 61 | Tubb5 | 5841 | 0.168 | 0.1867 | Yes |
| 62 | Mcm3 | 6018 | 0.159 | 0.1819 | Yes |
| 63 | Tmpo | 6247 | 0.154 | 0.1744 | Yes |
| 64 | Brms1l | 6285 | 0.153 | 0.1764 | Yes |
| 65 | Donson | 6304 | 0.151 | 0.1794 | Yes |
| 66 | Pold3 | 6311 | 0.151 | 0.1829 | Yes |
| 67 | Tk1 | 6400 | 0.148 | 0.1823 | Yes |
| 68 | Tra2b | 6410 | 0.147 | 0.1856 | Yes |
| 69 | Pttg1 | 6566 | 0.141 | 0.1814 | Yes |
| 70 | Ssrp1 | 6574 | 0.140 | 0.1846 | Yes |
| 71 | Lig1 | 6617 | 0.138 | 0.1860 | Yes |
| 72 | Nasp | 6708 | 0.133 | 0.1849 | Yes |
| 73 | Tubg1 | 6794 | 0.129 | 0.1839 | Yes |
| 74 | Mcm6 | 6815 | 0.128 | 0.1862 | Yes |
| 75 | Rfc1 | 6829 | 0.127 | 0.1888 | Yes |
| 76 | Bard1 | 7053 | 0.118 | 0.1806 | No |
| 77 | Mki67 | 7165 | 0.114 | 0.1779 | No |
| 78 | Wdr90 | 7269 | 0.109 | 0.1755 | No |
| 79 | Cdc25a | 7305 | 0.108 | 0.1765 | No |
| 80 | Asf1b | 7333 | 0.107 | 0.1778 | No |
| 81 | Nup107 | 7407 | 0.104 | 0.1768 | No |
| 82 | Ezh2 | 7478 | 0.101 | 0.1758 | No |
| 83 | Nap1l1 | 7517 | 0.099 | 0.1765 | No |
| 84 | Dctpp1 | 7771 | 0.087 | 0.1659 | No |
| 85 | Cenpm | 7855 | 0.083 | 0.1639 | No |
| 86 | Pold1 | 7921 | 0.081 | 0.1627 | No |
| 87 | Wee1 | 8020 | 0.077 | 0.1597 | No |
| 88 | Psip1 | 8091 | 0.074 | 0.1581 | No |
| 89 | Kif4 | 8155 | 0.071 | 0.1567 | No |
| 90 | Suv39h1 | 8248 | 0.067 | 0.1538 | No |
| 91 | Rpa1 | 8276 | 0.066 | 0.1541 | No |
| 92 | Cks2 | 8281 | 0.066 | 0.1556 | No |
| 93 | Smc6 | 8401 | 0.061 | 0.1512 | No |
| 94 | Pds5b | 8438 | 0.060 | 0.1509 | No |
| 95 | Pnn | 8442 | 0.059 | 0.1523 | No |
| 96 | Eif2s1 | 8451 | 0.059 | 0.1534 | No |
| 97 | Stag1 | 8462 | 0.058 | 0.1544 | No |
| 98 | Kif22 | 8688 | 0.049 | 0.1443 | No |
| 99 | Pms2 | 8744 | 0.047 | 0.1427 | No |
| 100 | Srsf2 | 8935 | 0.040 | 0.1342 | No |
| 101 | Pan2 | 8969 | 0.039 | 0.1335 | No |
| 102 | Nolc1 | 9004 | 0.038 | 0.1328 | No |
| 103 | Eed | 9049 | 0.036 | 0.1314 | No |
| 104 | Gspt1 | 9090 | 0.034 | 0.1303 | No |
| 105 | Mcm2 | 9098 | 0.033 | 0.1308 | No |
| 106 | Cnot9 | 9165 | 0.031 | 0.1283 | No |
| 107 | Spc24 | 9222 | 0.029 | 0.1262 | No |
| 108 | Mcm7 | 9321 | 0.024 | 0.1219 | No |
| 109 | Prim2 | 9323 | 0.024 | 0.1224 | No |
| 110 | Ccne1 | 9358 | 0.024 | 0.1213 | No |
| 111 | Chek2 | 9633 | 0.014 | 0.1079 | No |
| 112 | Mms22l | 9642 | 0.013 | 0.1078 | No |
| 113 | Pa2g4 | 9686 | 0.012 | 0.1060 | No |
| 114 | Brca1 | 9826 | 0.007 | 0.0991 | No |
| 115 | Zw10 | 9836 | 0.006 | 0.0988 | No |
| 116 | Hmgb2 | 9882 | 0.004 | 0.0967 | No |
| 117 | Nudt21 | 9939 | 0.002 | 0.0939 | No |
| 118 | Rpa3 | 9941 | 0.002 | 0.0939 | No |
| 119 | Mre11a | 9986 | 0.000 | 0.0917 | No |
| 120 | Tbrg4 | 10168 | -0.000 | 0.0826 | No |
| 121 | H2ax | 10213 | -0.002 | 0.0804 | No |
| 122 | Nup205 | 10284 | -0.005 | 0.0770 | No |
| 123 | Ccnb2 | 10345 | -0.007 | 0.0742 | No |
| 124 | Racgap1 | 10715 | -0.021 | 0.0561 | No |
| 125 | Snrpb | 10882 | -0.027 | 0.0484 | No |
| 126 | Ak2 | 10930 | -0.029 | 0.0468 | No |
| 127 | Mthfd2 | 11019 | -0.033 | 0.0432 | No |
| 128 | H2az1 | 11062 | -0.035 | 0.0419 | No |
| 129 | Cit | 11064 | -0.035 | 0.0428 | No |
| 130 | Lsm8 | 11073 | -0.035 | 0.0433 | No |
| 131 | Diaph3 | 11180 | -0.040 | 0.0390 | No |
| 132 | Ppm1d | 11473 | -0.051 | 0.0256 | No |
| 133 | Ube2s | 11602 | -0.056 | 0.0205 | No |
| 134 | Hells | 11616 | -0.057 | 0.0213 | No |
| 135 | Rad50 | 11772 | -0.063 | 0.0151 | No |
| 136 | Nup153 | 11778 | -0.063 | 0.0165 | No |
| 137 | Pold2 | 11999 | -0.072 | 0.0072 | No |
| 138 | Slbp | 12055 | -0.074 | 0.0064 | No |
| 139 | Exosc8 | 12319 | -0.084 | -0.0047 | No |
| 140 | Smc4 | 12449 | -0.091 | -0.0089 | No |
| 141 | Dut | 12451 | -0.091 | -0.0066 | No |
| 142 | Pcna | 12454 | -0.091 | -0.0044 | No |
| 143 | Ubr7 | 12457 | -0.091 | -0.0022 | No |
| 144 | Chek1 | 12464 | -0.091 | -0.0001 | No |
| 145 | Brca2 | 12500 | -0.093 | 0.0005 | No |
| 146 | Usp1 | 12579 | -0.096 | -0.0010 | No |
| 147 | Ppp1r8 | 12867 | -0.108 | -0.0127 | No |
| 148 | E2f8 | 12887 | -0.108 | -0.0109 | No |
| 149 | Cks1b | 12941 | -0.110 | -0.0108 | No |
| 150 | Pole4 | 13092 | -0.114 | -0.0154 | No |
| 151 | Tipin | 13176 | -0.118 | -0.0166 | No |
| 152 | Lyar | 13337 | -0.124 | -0.0215 | No |
| 153 | Trip13 | 13515 | -0.130 | -0.0271 | No |
| 154 | Dek | 13540 | -0.131 | -0.0250 | No |
| 155 | Aurka | 13694 | -0.138 | -0.0291 | No |
| 156 | Dclre1b | 13782 | -0.142 | -0.0299 | No |
| 157 | Hmga1b | 13824 | -0.144 | -0.0283 | No |
| 158 | Pole | 13873 | -0.146 | -0.0270 | No |
| 159 | Luc7l3 | 13921 | -0.148 | -0.0255 | No |
| 160 | Prps1 | 14006 | -0.152 | -0.0259 | No |
| 161 | Rfc2 | 14129 | -0.157 | -0.0280 | No |
| 162 | Ranbp1 | 14192 | -0.159 | -0.0271 | No |
| 163 | Mlh1 | 14469 | -0.173 | -0.0366 | No |
| 164 | Paics | 14735 | -0.185 | -0.0452 | No |
| 165 | Psmc3ip | 14775 | -0.187 | -0.0424 | No |
| 166 | Spc25 | 15024 | -0.200 | -0.0498 | No |
| 167 | Nbn | 15145 | -0.206 | -0.0505 | No |
| 168 | Asf1a | 15413 | -0.215 | -0.0585 | No |
| 169 | Rrm2 | 15508 | -0.219 | -0.0576 | No |
| 170 | Trp53 | 15777 | -0.230 | -0.0653 | No |
| 171 | Pop7 | 15795 | -0.232 | -0.0602 | No |
| 172 | Orc2 | 16101 | -0.250 | -0.0692 | No |
| 173 | Pola2 | 16399 | -0.268 | -0.0773 | No |
| 174 | Gins4 | 16672 | -0.281 | -0.0838 | No |
| 175 | Cdkn1b | 16691 | -0.283 | -0.0775 | No |
| 176 | Myc | 16912 | -0.295 | -0.0810 | No |
| 177 | Cdk4 | 16993 | -0.301 | -0.0774 | No |
| 178 | Dscc1 | 17059 | -0.303 | -0.0729 | No |
| 179 | Tfrc | 17154 | -0.309 | -0.0697 | No |
| 180 | Gins3 | 17457 | -0.327 | -0.0766 | No |
| 181 | Rad1 | 17462 | -0.327 | -0.0684 | No |
| 182 | Hmgb3 | 17540 | -0.331 | -0.0638 | No |
| 183 | Ing3 | 17562 | -0.332 | -0.0564 | No |
| 184 | Nme1 | 17620 | -0.336 | -0.0506 | No |
| 185 | Hus1 | 17915 | -0.360 | -0.0562 | No |
| 186 | Ran | 18130 | -0.378 | -0.0574 | No |
| 187 | Rad51c | 18183 | -0.384 | -0.0502 | No |
| 188 | Rad51ap1 | 18418 | -0.403 | -0.0516 | No |
| 189 | Rpa2 | 18522 | -0.411 | -0.0463 | No |
| 190 | Tcf19 | 18788 | -0.440 | -0.0484 | No |
| 191 | Gins1 | 19009 | -0.472 | -0.0474 | No |
| 192 | Orc6 | 19049 | -0.477 | -0.0372 | No |
| 193 | Prdx4 | 19458 | -0.562 | -0.0434 | No |
| 194 | Rfc3 | 19505 | -0.572 | -0.0311 | No |
| 195 | Cdkn1a | 19559 | -0.586 | -0.0187 | No |
| 196 | Stmn1 | 19905 | -0.772 | -0.0164 | No |
| 197 | Cdca3 | 19972 | -0.876 | 0.0027 | No |

