| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group3.GMP.neu_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_P53_PATHWAY |
| Enrichment Score (ES) | -0.21362537 |
| Normalized Enrichment Score (NES) | -1.037525 |
| Nominal p-value | 0.38535646 |
| FDR q-value | 0.75445294 |
| FWER p-Value | 0.985 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hmox1 | 86 | 0.843 | 0.0168 | No |
| 2 | Plk2 | 116 | 0.818 | 0.0358 | No |
| 3 | Klf4 | 190 | 0.736 | 0.0505 | No |
| 4 | Tgfa | 307 | 0.656 | 0.0611 | No |
| 5 | Aen | 465 | 0.587 | 0.0678 | No |
| 6 | Jun | 910 | 0.477 | 0.0574 | No |
| 7 | Sphk1 | 1194 | 0.434 | 0.0540 | No |
| 8 | Dcxr | 1334 | 0.416 | 0.0574 | No |
| 9 | Fgf13 | 1448 | 0.401 | 0.0618 | No |
| 10 | Alox8 | 1744 | 0.370 | 0.0561 | No |
| 11 | Iscu | 2009 | 0.344 | 0.0514 | No |
| 12 | Atf3 | 2297 | 0.323 | 0.0451 | No |
| 13 | Itgb4 | 2356 | 0.318 | 0.0501 | No |
| 14 | Stom | 2381 | 0.316 | 0.0568 | No |
| 15 | Rab40c | 2479 | 0.307 | 0.0596 | No |
| 16 | Rrad | 2535 | 0.302 | 0.0644 | No |
| 17 | Ephx1 | 2577 | 0.299 | 0.0698 | No |
| 18 | Mdm2 | 2656 | 0.292 | 0.0732 | No |
| 19 | Foxo3 | 2690 | 0.290 | 0.0788 | No |
| 20 | Sfn | 2703 | 0.288 | 0.0854 | No |
| 21 | Abcc5 | 2768 | 0.284 | 0.0892 | No |
| 22 | Rad9a | 2877 | 0.278 | 0.0907 | No |
| 23 | Trafd1 | 2924 | 0.274 | 0.0953 | No |
| 24 | Ldhb | 2956 | 0.272 | 0.1005 | No |
| 25 | Polh | 3094 | 0.264 | 0.1002 | No |
| 26 | Ddb2 | 3457 | 0.240 | 0.0880 | No |
| 27 | Nudt15 | 3674 | 0.230 | 0.0829 | No |
| 28 | Eps8l2 | 3934 | 0.218 | 0.0753 | No |
| 29 | Elp1 | 4177 | 0.210 | 0.0683 | No |
| 30 | Slc3a2 | 4286 | 0.204 | 0.0680 | No |
| 31 | Btg1 | 4418 | 0.198 | 0.0664 | No |
| 32 | Hdac3 | 4426 | 0.197 | 0.0709 | No |
| 33 | Cdh13 | 4643 | 0.187 | 0.0647 | No |
| 34 | H2ac25 | 4646 | 0.187 | 0.0693 | No |
| 35 | Hexim1 | 4769 | 0.182 | 0.0677 | No |
| 36 | Cd82 | 4839 | 0.179 | 0.0687 | No |
| 37 | Prkab1 | 5205 | 0.163 | 0.0544 | No |
| 38 | Kif13b | 5274 | 0.159 | 0.0550 | No |
| 39 | Ercc5 | 5292 | 0.159 | 0.0581 | No |
| 40 | Hspa4l | 5418 | 0.154 | 0.0556 | No |
| 41 | Rhbdf2 | 5512 | 0.150 | 0.0547 | No |
| 42 | Sat1 | 5528 | 0.150 | 0.0577 | No |
| 43 | Ppp1r15a | 5618 | 0.146 | 0.0569 | No |
| 44 | Ccnk | 5757 | 0.138 | 0.0534 | No |
| 45 | Pom121 | 5771 | 0.138 | 0.0562 | No |
| 46 | Ccp110 | 5902 | 0.132 | 0.0529 | No |
| 47 | H2aj | 5904 | 0.132 | 0.0562 | No |
| 48 | Gadd45a | 6086 | 0.125 | 0.0502 | No |
| 49 | Slc7a11 | 6133 | 0.124 | 0.0510 | No |
| 50 | Cyfip2 | 6333 | 0.116 | 0.0438 | No |
| 51 | Fdxr | 6508 | 0.108 | 0.0378 | No |
| 52 | Tap1 | 6509 | 0.108 | 0.0405 | No |
| 53 | Rpl18 | 6529 | 0.108 | 0.0422 | No |
| 54 | Fam162a | 6602 | 0.105 | 0.0412 | No |
| 55 | Tob1 | 6750 | 0.099 | 0.0363 | No |
| 56 | Slc35d1 | 7004 | 0.090 | 0.0258 | No |
| 57 | Bax | 7018 | 0.089 | 0.0274 | No |
| 58 | Notch1 | 7162 | 0.083 | 0.0222 | No |
| 59 | Tchh | 7449 | 0.075 | 0.0097 | No |
| 60 | Apaf1 | 7522 | 0.072 | 0.0079 | No |
| 61 | S100a10 | 7581 | 0.070 | 0.0067 | No |
| 62 | Sesn1 | 7585 | 0.070 | 0.0083 | No |
| 63 | Zfp36l1 | 7770 | 0.063 | 0.0006 | No |
| 64 | Ada | 7874 | 0.059 | -0.0031 | No |
| 65 | Baiap2 | 7958 | 0.055 | -0.0059 | No |
| 66 | Sp1 | 8142 | 0.049 | -0.0139 | No |
| 67 | Abat | 8198 | 0.046 | -0.0155 | No |
| 68 | Jag2 | 8202 | 0.046 | -0.0145 | No |
| 69 | Tnfsf9 | 8208 | 0.046 | -0.0136 | No |
| 70 | Gls2 | 8212 | 0.046 | -0.0126 | No |
| 71 | Prmt2 | 8569 | 0.032 | -0.0298 | No |
| 72 | Triap1 | 8663 | 0.029 | -0.0337 | No |
| 73 | Nol8 | 8758 | 0.026 | -0.0378 | No |
| 74 | Fbxw7 | 8810 | 0.024 | -0.0398 | No |
| 75 | Dram1 | 8904 | 0.020 | -0.0440 | No |
| 76 | Tax1bp3 | 9010 | 0.017 | -0.0488 | No |
| 77 | Hbegf | 9179 | 0.011 | -0.0570 | No |
| 78 | Mapkapk3 | 9609 | -0.002 | -0.0786 | No |
| 79 | Hras | 9670 | -0.004 | -0.0815 | No |
| 80 | Wrap73 | 9766 | -0.007 | -0.0861 | No |
| 81 | Csrnp2 | 9776 | -0.008 | -0.0864 | No |
| 82 | Txnip | 9873 | -0.011 | -0.0909 | No |
| 83 | Rb1 | 9943 | -0.013 | -0.0941 | No |
| 84 | Cdkn1a | 10117 | -0.019 | -0.1023 | No |
| 85 | H1f2 | 10318 | -0.026 | -0.1117 | No |
| 86 | Acvr1b | 10593 | -0.036 | -0.1246 | No |
| 87 | Ccng1 | 10636 | -0.038 | -0.1258 | No |
| 88 | Pcna | 10657 | -0.039 | -0.1259 | No |
| 89 | Mknk2 | 10682 | -0.040 | -0.1261 | No |
| 90 | Cdkn2aip | 10796 | -0.044 | -0.1307 | No |
| 91 | Ptpn14 | 10916 | -0.048 | -0.1355 | No |
| 92 | Procr | 10936 | -0.049 | -0.1352 | No |
| 93 | Irag2 | 11083 | -0.054 | -0.1412 | No |
| 94 | Ei24 | 11120 | -0.055 | -0.1416 | No |
| 95 | Tspyl2 | 11194 | -0.057 | -0.1439 | No |
| 96 | Plk3 | 11500 | -0.067 | -0.1576 | No |
| 97 | Ppm1d | 11614 | -0.072 | -0.1615 | No |
| 98 | Rpl36 | 11731 | -0.077 | -0.1654 | No |
| 99 | Mxd4 | 11838 | -0.081 | -0.1687 | No |
| 100 | Ifi30 | 11931 | -0.084 | -0.1712 | No |
| 101 | F2r | 12120 | -0.091 | -0.1784 | No |
| 102 | Def6 | 12300 | -0.098 | -0.1850 | No |
| 103 | Cdk5r1 | 12496 | -0.106 | -0.1922 | No |
| 104 | Btg2 | 12511 | -0.107 | -0.1902 | No |
| 105 | Trp53 | 12517 | -0.107 | -0.1878 | No |
| 106 | Osgin1 | 12563 | -0.109 | -0.1873 | No |
| 107 | Ip6k2 | 12616 | -0.111 | -0.1871 | No |
| 108 | Rps27l | 12798 | -0.119 | -0.1933 | No |
| 109 | Hint1 | 12916 | -0.121 | -0.1961 | No |
| 110 | Vdr | 13041 | -0.125 | -0.1993 | No |
| 111 | Casp1 | 13117 | -0.129 | -0.1998 | No |
| 112 | Dnttip2 | 13155 | -0.130 | -0.1984 | No |
| 113 | Rnf19b | 13177 | -0.131 | -0.1962 | No |
| 114 | Fuca1 | 13223 | -0.133 | -0.1952 | No |
| 115 | Slc19a2 | 13226 | -0.133 | -0.1919 | No |
| 116 | St14 | 13333 | -0.137 | -0.1939 | No |
| 117 | Ndrg1 | 13369 | -0.138 | -0.1922 | No |
| 118 | App | 13372 | -0.138 | -0.1888 | No |
| 119 | Mxd1 | 13460 | -0.142 | -0.1896 | No |
| 120 | Ctsf | 13530 | -0.144 | -0.1895 | No |
| 121 | Sec61a1 | 13577 | -0.146 | -0.1882 | No |
| 122 | Bak1 | 13708 | -0.151 | -0.1910 | No |
| 123 | Rap2b | 13710 | -0.151 | -0.1872 | No |
| 124 | Tsc22d1 | 13714 | -0.151 | -0.1836 | No |
| 125 | Pidd1 | 13868 | -0.158 | -0.1874 | No |
| 126 | Ninj1 | 13870 | -0.158 | -0.1835 | No |
| 127 | Wwp1 | 13972 | -0.162 | -0.1845 | No |
| 128 | Pdgfa | 13990 | -0.163 | -0.1813 | No |
| 129 | Tm7sf3 | 14073 | -0.166 | -0.1813 | No |
| 130 | Tprkb | 14183 | -0.171 | -0.1825 | No |
| 131 | Retsat | 14434 | -0.181 | -0.1906 | No |
| 132 | Ptpre | 14843 | -0.198 | -0.2062 | No |
| 133 | Ccnd3 | 14901 | -0.201 | -0.2040 | No |
| 134 | Coq8a | 15039 | -0.207 | -0.2057 | No |
| 135 | Rchy1 | 15167 | -0.214 | -0.2068 | No |
| 136 | Ctsd | 15226 | -0.217 | -0.2043 | No |
| 137 | Zmat3 | 15413 | -0.227 | -0.2080 | Yes |
| 138 | S100a4 | 15465 | -0.229 | -0.2048 | Yes |
| 139 | Ier5 | 15500 | -0.229 | -0.2008 | Yes |
| 140 | Cebpa | 15571 | -0.233 | -0.1985 | Yes |
| 141 | Xpc | 15645 | -0.237 | -0.1962 | Yes |
| 142 | Pitpnc1 | 15707 | -0.239 | -0.1933 | Yes |
| 143 | Trib3 | 15743 | -0.242 | -0.1890 | Yes |
| 144 | Tcn2 | 16034 | -0.255 | -0.1973 | Yes |
| 145 | Zbtb16 | 16056 | -0.256 | -0.1919 | Yes |
| 146 | Socs1 | 16103 | -0.259 | -0.1877 | Yes |
| 147 | Pmm1 | 16127 | -0.260 | -0.1824 | Yes |
| 148 | Dgka | 16196 | -0.264 | -0.1792 | Yes |
| 149 | Fos | 16197 | -0.264 | -0.1726 | Yes |
| 150 | Nupr1 | 16231 | -0.265 | -0.1677 | Yes |
| 151 | Perp | 16368 | -0.274 | -0.1677 | Yes |
| 152 | Ak1 | 16604 | -0.289 | -0.1723 | Yes |
| 153 | Vwa5a | 16643 | -0.291 | -0.1669 | Yes |
| 154 | Rrp8 | 16787 | -0.299 | -0.1666 | Yes |
| 155 | Ccnd2 | 16936 | -0.307 | -0.1664 | Yes |
| 156 | Plxnb2 | 17043 | -0.313 | -0.1640 | Yes |
| 157 | Steap3 | 17267 | -0.326 | -0.1670 | Yes |
| 158 | Tgfb1 | 17328 | -0.329 | -0.1618 | Yes |
| 159 | Ddit4 | 17332 | -0.330 | -0.1537 | Yes |
| 160 | Trp63 | 17441 | -0.337 | -0.1507 | Yes |
| 161 | Rps12 | 17465 | -0.338 | -0.1434 | Yes |
| 162 | Pvt1 | 17571 | -0.345 | -0.1401 | Yes |
| 163 | Blcap | 17779 | -0.360 | -0.1415 | Yes |
| 164 | Rgs16 | 17858 | -0.367 | -0.1362 | Yes |
| 165 | Rad51c | 17885 | -0.370 | -0.1283 | Yes |
| 166 | Sdc1 | 17969 | -0.377 | -0.1231 | Yes |
| 167 | Klk8 | 17995 | -0.378 | -0.1149 | Yes |
| 168 | Cgrrf1 | 18032 | -0.381 | -0.1071 | Yes |
| 169 | Rack1 | 18237 | -0.401 | -0.1074 | Yes |
| 170 | Cd81 | 18276 | -0.406 | -0.0991 | Yes |
| 171 | Rxra | 18388 | -0.416 | -0.0943 | Yes |
| 172 | Irak1 | 18446 | -0.424 | -0.0866 | Yes |
| 173 | Sertad3 | 18842 | -0.466 | -0.0948 | Yes |
| 174 | Abhd4 | 18898 | -0.474 | -0.0858 | Yes |
| 175 | Ralgds | 19051 | -0.494 | -0.0811 | Yes |
| 176 | Ankra2 | 19204 | -0.520 | -0.0757 | Yes |
| 177 | Fas | 19313 | -0.541 | -0.0676 | Yes |
| 178 | Ier3 | 19366 | -0.551 | -0.0564 | Yes |
| 179 | Ddit3 | 19507 | -0.585 | -0.0489 | Yes |
| 180 | Tpd52l1 | 19546 | -0.593 | -0.0359 | Yes |
| 181 | Vamp8 | 19681 | -0.638 | -0.0267 | Yes |
| 182 | Gm2a | 19808 | -0.695 | -0.0157 | Yes |
| 183 | Traf4 | 20012 | -1.065 | 0.0007 | Yes |

