| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group3.GMP.neu_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.28386414 |
| Normalized Enrichment Score (NES) | 1.1893463 |
| Nominal p-value | 0.29942417 |
| FDR q-value | 0.9177874 |
| FWER p-Value | 0.903 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccne1 | 181 | 0.744 | 0.0123 | Yes |
| 2 | Pttg1 | 195 | 0.732 | 0.0328 | Yes |
| 3 | Donson | 713 | 0.520 | 0.0217 | Yes |
| 4 | Cdca8 | 872 | 0.483 | 0.0276 | Yes |
| 5 | Ipo7 | 1004 | 0.462 | 0.0343 | Yes |
| 6 | Rad21 | 1093 | 0.450 | 0.0428 | Yes |
| 7 | Srsf1 | 1129 | 0.444 | 0.0539 | Yes |
| 8 | Bub1b | 1217 | 0.431 | 0.0619 | Yes |
| 9 | Ube2s | 1275 | 0.426 | 0.0713 | Yes |
| 10 | Dck | 1337 | 0.416 | 0.0802 | Yes |
| 11 | Hnrnpd | 1453 | 0.401 | 0.0859 | Yes |
| 12 | Mxd3 | 1470 | 0.399 | 0.0966 | Yes |
| 13 | Shmt1 | 1537 | 0.392 | 0.1046 | Yes |
| 14 | Tra2b | 1832 | 0.360 | 0.1001 | Yes |
| 15 | Xpo1 | 1936 | 0.351 | 0.1050 | Yes |
| 16 | Cks2 | 1982 | 0.345 | 0.1127 | Yes |
| 17 | Kif22 | 2078 | 0.339 | 0.1177 | Yes |
| 18 | Syncrip | 2166 | 0.334 | 0.1229 | Yes |
| 19 | Anp32e | 2176 | 0.332 | 0.1320 | Yes |
| 20 | Cse1l | 2241 | 0.328 | 0.1382 | Yes |
| 21 | Prkdc | 2300 | 0.323 | 0.1446 | Yes |
| 22 | Kif2c | 2320 | 0.320 | 0.1529 | Yes |
| 23 | Rbbp7 | 2380 | 0.316 | 0.1590 | Yes |
| 24 | Smc3 | 2405 | 0.314 | 0.1669 | Yes |
| 25 | Atad2 | 2518 | 0.304 | 0.1700 | Yes |
| 26 | Hells | 2589 | 0.298 | 0.1750 | Yes |
| 27 | Cenpe | 2624 | 0.295 | 0.1818 | Yes |
| 28 | Lbr | 2788 | 0.283 | 0.1817 | Yes |
| 29 | Dnmt1 | 2802 | 0.281 | 0.1892 | Yes |
| 30 | Brms1l | 2857 | 0.279 | 0.1945 | Yes |
| 31 | Lmnb1 | 2889 | 0.277 | 0.2009 | Yes |
| 32 | Cdk1 | 2947 | 0.273 | 0.2059 | Yes |
| 33 | Top2a | 2977 | 0.271 | 0.2123 | Yes |
| 34 | Birc5 | 2996 | 0.269 | 0.2191 | Yes |
| 35 | Nup107 | 3070 | 0.266 | 0.2231 | Yes |
| 36 | Pnn | 3480 | 0.239 | 0.2093 | Yes |
| 37 | Plk1 | 3528 | 0.236 | 0.2138 | Yes |
| 38 | Rpa1 | 3585 | 0.234 | 0.2177 | Yes |
| 39 | Dut | 3791 | 0.224 | 0.2138 | Yes |
| 40 | Plk4 | 3928 | 0.218 | 0.2132 | Yes |
| 41 | Mcm3 | 3980 | 0.218 | 0.2169 | Yes |
| 42 | Ilf3 | 4018 | 0.216 | 0.2213 | Yes |
| 43 | Zw10 | 4025 | 0.216 | 0.2272 | Yes |
| 44 | Cdc25a | 4091 | 0.213 | 0.2301 | Yes |
| 45 | Exosc8 | 4145 | 0.211 | 0.2335 | Yes |
| 46 | Nasp | 4231 | 0.207 | 0.2352 | Yes |
| 47 | Ddx39a | 4310 | 0.203 | 0.2371 | Yes |
| 48 | Cbx5 | 4395 | 0.199 | 0.2386 | Yes |
| 49 | Mki67 | 4499 | 0.195 | 0.2390 | Yes |
| 50 | Rad51ap1 | 4519 | 0.194 | 0.2436 | Yes |
| 51 | Psmc3ip | 4730 | 0.184 | 0.2383 | Yes |
| 52 | Racgap1 | 4760 | 0.183 | 0.2421 | Yes |
| 53 | Brca1 | 4859 | 0.178 | 0.2423 | Yes |
| 54 | Kif4 | 4910 | 0.176 | 0.2449 | Yes |
| 55 | Tfrc | 4975 | 0.173 | 0.2466 | Yes |
| 56 | Pms2 | 5022 | 0.171 | 0.2492 | Yes |
| 57 | Tbrg4 | 5029 | 0.171 | 0.2539 | Yes |
| 58 | Trip13 | 5117 | 0.167 | 0.2543 | Yes |
| 59 | Aurkb | 5124 | 0.166 | 0.2588 | Yes |
| 60 | Mcm4 | 5134 | 0.166 | 0.2631 | Yes |
| 61 | Wee1 | 5206 | 0.163 | 0.2642 | Yes |
| 62 | Mcm5 | 5211 | 0.162 | 0.2687 | Yes |
| 63 | Rpa3 | 5590 | 0.147 | 0.2538 | Yes |
| 64 | Suv39h1 | 5591 | 0.147 | 0.2581 | Yes |
| 65 | Cit | 5661 | 0.144 | 0.2587 | Yes |
| 66 | Nolc1 | 5678 | 0.143 | 0.2621 | Yes |
| 67 | Hmmr | 5782 | 0.137 | 0.2608 | Yes |
| 68 | Nudt21 | 5898 | 0.132 | 0.2588 | Yes |
| 69 | Ccp110 | 5902 | 0.132 | 0.2625 | Yes |
| 70 | Stag1 | 5903 | 0.132 | 0.2663 | Yes |
| 71 | Chek2 | 5929 | 0.131 | 0.2688 | Yes |
| 72 | Smc1a | 5942 | 0.131 | 0.2720 | Yes |
| 73 | Tk1 | 6002 | 0.128 | 0.2727 | Yes |
| 74 | Phf5a | 6122 | 0.124 | 0.2703 | Yes |
| 75 | Mcm2 | 6139 | 0.123 | 0.2730 | Yes |
| 76 | Jpt1 | 6141 | 0.123 | 0.2765 | Yes |
| 77 | Ubr7 | 6154 | 0.123 | 0.2794 | Yes |
| 78 | Mms22l | 6204 | 0.121 | 0.2805 | Yes |
| 79 | Pan2 | 6269 | 0.118 | 0.2806 | Yes |
| 80 | Usp1 | 6425 | 0.112 | 0.2760 | Yes |
| 81 | Lig1 | 6479 | 0.109 | 0.2765 | Yes |
| 82 | Pds5b | 6501 | 0.109 | 0.2786 | Yes |
| 83 | Pold3 | 6505 | 0.109 | 0.2816 | Yes |
| 84 | Chek1 | 6549 | 0.107 | 0.2825 | Yes |
| 85 | Nop56 | 6583 | 0.106 | 0.2839 | Yes |
| 86 | Psip1 | 6787 | 0.098 | 0.2764 | No |
| 87 | Espl1 | 6870 | 0.095 | 0.2750 | No |
| 88 | Gspt1 | 6872 | 0.095 | 0.2777 | No |
| 89 | E2f8 | 7027 | 0.089 | 0.2725 | No |
| 90 | Eif2s1 | 7070 | 0.087 | 0.2729 | No |
| 91 | Cdkn2c | 7239 | 0.081 | 0.2668 | No |
| 92 | Smc6 | 7397 | 0.077 | 0.2611 | No |
| 93 | Nup205 | 7400 | 0.077 | 0.2632 | No |
| 94 | Mre11a | 7414 | 0.076 | 0.2647 | No |
| 95 | Mcm6 | 7487 | 0.074 | 0.2632 | No |
| 96 | Nap1l1 | 7646 | 0.068 | 0.2572 | No |
| 97 | Nup153 | 7653 | 0.068 | 0.2589 | No |
| 98 | Ube2t | 7704 | 0.065 | 0.2582 | No |
| 99 | Prdx4 | 7789 | 0.062 | 0.2558 | No |
| 100 | Mlh1 | 7867 | 0.059 | 0.2536 | No |
| 101 | Rrm2 | 7883 | 0.058 | 0.2545 | No |
| 102 | Dlgap5 | 7971 | 0.054 | 0.2517 | No |
| 103 | Bard1 | 8069 | 0.052 | 0.2483 | No |
| 104 | Msh2 | 8211 | 0.046 | 0.2425 | No |
| 105 | Ncapd2 | 8333 | 0.041 | 0.2376 | No |
| 106 | Cnot9 | 8396 | 0.038 | 0.2356 | No |
| 107 | Rad50 | 8419 | 0.038 | 0.2355 | No |
| 108 | Pole | 8437 | 0.037 | 0.2357 | No |
| 109 | Rpa2 | 8455 | 0.036 | 0.2359 | No |
| 110 | Tmpo | 8499 | 0.035 | 0.2347 | No |
| 111 | Prim2 | 8507 | 0.034 | 0.2354 | No |
| 112 | Nbn | 8538 | 0.033 | 0.2348 | No |
| 113 | Ezh2 | 8582 | 0.032 | 0.2336 | No |
| 114 | Gins4 | 8627 | 0.030 | 0.2322 | No |
| 115 | Pa2g4 | 8643 | 0.030 | 0.2323 | No |
| 116 | Gins1 | 8800 | 0.025 | 0.2252 | No |
| 117 | Spag5 | 8971 | 0.018 | 0.2171 | No |
| 118 | Mybl2 | 8976 | 0.018 | 0.2174 | No |
| 119 | Dclre1b | 9033 | 0.016 | 0.2151 | No |
| 120 | Ssrp1 | 9206 | 0.010 | 0.2067 | No |
| 121 | Aurka | 9332 | 0.006 | 0.2005 | No |
| 122 | Cdkn1b | 9370 | 0.004 | 0.1988 | No |
| 123 | Orc2 | 9376 | 0.004 | 0.1987 | No |
| 124 | Brca2 | 9643 | -0.003 | 0.1853 | No |
| 125 | H2az1 | 9719 | -0.006 | 0.1817 | No |
| 126 | Hmgb2 | 9815 | -0.009 | 0.1772 | No |
| 127 | Pola2 | 9881 | -0.011 | 0.1742 | No |
| 128 | Tacc3 | 9894 | -0.011 | 0.1739 | No |
| 129 | Kif18b | 10017 | -0.016 | 0.1682 | No |
| 130 | Dctpp1 | 10064 | -0.017 | 0.1664 | No |
| 131 | Lsm8 | 10086 | -0.018 | 0.1659 | No |
| 132 | Ctcf | 10094 | -0.018 | 0.1660 | No |
| 133 | Cdkn1a | 10117 | -0.019 | 0.1655 | No |
| 134 | Ran | 10276 | -0.025 | 0.1582 | No |
| 135 | Eed | 10308 | -0.026 | 0.1574 | No |
| 136 | Timeless | 10338 | -0.027 | 0.1567 | No |
| 137 | Rfc1 | 10378 | -0.028 | 0.1556 | No |
| 138 | Diaph3 | 10425 | -0.030 | 0.1541 | No |
| 139 | Cdc20 | 10435 | -0.030 | 0.1545 | No |
| 140 | Srsf2 | 10513 | -0.033 | 0.1516 | No |
| 141 | Pcna | 10657 | -0.039 | 0.1455 | No |
| 142 | Pop7 | 10675 | -0.039 | 0.1458 | No |
| 143 | Mcm7 | 10749 | -0.042 | 0.1433 | No |
| 144 | Melk | 10751 | -0.042 | 0.1445 | No |
| 145 | Luc7l3 | 10754 | -0.042 | 0.1456 | No |
| 146 | Depdc1a | 10792 | -0.044 | 0.1450 | No |
| 147 | Spc25 | 10867 | -0.046 | 0.1426 | No |
| 148 | Tubb5 | 10971 | -0.050 | 0.1388 | No |
| 149 | Pold1 | 10999 | -0.051 | 0.1389 | No |
| 150 | Xrcc6 | 11101 | -0.054 | 0.1354 | No |
| 151 | Hmgb3 | 11254 | -0.059 | 0.1294 | No |
| 152 | Ung | 11293 | -0.060 | 0.1293 | No |
| 153 | Mthfd2 | 11317 | -0.062 | 0.1299 | No |
| 154 | Ppm1d | 11614 | -0.072 | 0.1170 | No |
| 155 | Ak2 | 11975 | -0.086 | 0.1013 | No |
| 156 | Lyar | 12014 | -0.087 | 0.1019 | No |
| 157 | Wdr90 | 12108 | -0.091 | 0.0999 | No |
| 158 | Smc4 | 12123 | -0.091 | 0.1018 | No |
| 159 | Pold2 | 12306 | -0.098 | 0.0954 | No |
| 160 | Prps1 | 12366 | -0.101 | 0.0954 | No |
| 161 | Ppp1r8 | 12368 | -0.101 | 0.0982 | No |
| 162 | Slbp | 12509 | -0.107 | 0.0942 | No |
| 163 | Trp53 | 12517 | -0.107 | 0.0970 | No |
| 164 | Tipin | 12577 | -0.110 | 0.0972 | No |
| 165 | Rfc3 | 12634 | -0.112 | 0.0976 | No |
| 166 | Dek | 12932 | -0.121 | 0.0861 | No |
| 167 | Cdc25b | 13600 | -0.146 | 0.0567 | No |
| 168 | Hus1 | 13800 | -0.155 | 0.0511 | No |
| 169 | Orc6 | 13810 | -0.155 | 0.0551 | No |
| 170 | Asf1b | 14189 | -0.171 | 0.0410 | No |
| 171 | Ccnb2 | 14201 | -0.172 | 0.0454 | No |
| 172 | Rnaseh2a | 14265 | -0.174 | 0.0472 | No |
| 173 | Spc24 | 14368 | -0.178 | 0.0472 | No |
| 174 | Paics | 14894 | -0.200 | 0.0265 | No |
| 175 | Tubg1 | 14988 | -0.205 | 0.0277 | No |
| 176 | Cks1b | 15145 | -0.213 | 0.0260 | No |
| 177 | Cenpm | 15150 | -0.213 | 0.0319 | No |
| 178 | Asf1a | 15195 | -0.216 | 0.0359 | No |
| 179 | Rfc2 | 15239 | -0.218 | 0.0400 | No |
| 180 | Snrpb | 15745 | -0.242 | 0.0215 | No |
| 181 | Ranbp1 | 16012 | -0.254 | 0.0154 | No |
| 182 | H2ax | 16458 | -0.280 | 0.0011 | No |
| 183 | Tcf19 | 16745 | -0.295 | -0.0048 | No |
| 184 | Mad2l1 | 16806 | -0.300 | 0.0008 | No |
| 185 | Gins3 | 16856 | -0.303 | 0.0070 | No |
| 186 | Cdkn3 | 17040 | -0.313 | 0.0068 | No |
| 187 | Cdca3 | 17382 | -0.333 | -0.0008 | No |
| 188 | Pole4 | 17515 | -0.342 | 0.0024 | No |
| 189 | Rad51c | 17885 | -0.370 | -0.0055 | No |
| 190 | Nme1 | 17932 | -0.374 | 0.0029 | No |
| 191 | Hmga1b | 18287 | -0.406 | -0.0032 | No |
| 192 | Cdk4 | 18754 | -0.455 | -0.0136 | No |
| 193 | Rad1 | 18773 | -0.458 | -0.0013 | No |
| 194 | Myc | 19254 | -0.530 | -0.0103 | No |
| 195 | Ing3 | 19264 | -0.532 | 0.0046 | No |
| 196 | Dscc1 | 19326 | -0.543 | 0.0172 | No |
| 197 | Stmn1 | 19648 | -0.627 | 0.0191 | No |

