| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group3.GMP.neu_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.26597464 |
| Normalized Enrichment Score (NES) | -1.0746038 |
| Nominal p-value | 0.35742188 |
| FDR q-value | 0.73741686 |
| FWER p-Value | 0.974 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Nlrp3 | 73 | 0.865 | 0.0206 | No |
| 2 | Egfr | 460 | 0.588 | 0.0177 | No |
| 3 | Cd1d2 | 523 | 0.575 | 0.0307 | No |
| 4 | Dyrk3 | 626 | 0.547 | 0.0408 | No |
| 5 | Cd79a | 790 | 0.504 | 0.0468 | No |
| 6 | Ly86 | 878 | 0.483 | 0.0559 | No |
| 7 | Il4 | 917 | 0.476 | 0.0673 | No |
| 8 | Ctss | 1198 | 0.434 | 0.0654 | No |
| 9 | Rpl3l | 1486 | 0.397 | 0.0621 | No |
| 10 | Tlr6 | 1584 | 0.387 | 0.0681 | No |
| 11 | Ripk2 | 1739 | 0.370 | 0.0707 | No |
| 12 | Il2ra | 1879 | 0.355 | 0.0737 | No |
| 13 | Ltb | 2071 | 0.340 | 0.0736 | No |
| 14 | Jak2 | 2213 | 0.330 | 0.0757 | No |
| 15 | Eif3a | 2260 | 0.326 | 0.0825 | No |
| 16 | Cd4 | 2331 | 0.320 | 0.0880 | No |
| 17 | Il10 | 2358 | 0.318 | 0.0956 | No |
| 18 | Stat1 | 2431 | 0.311 | 0.1007 | No |
| 19 | Cd74 | 2561 | 0.300 | 0.1026 | No |
| 20 | Tapbp | 2643 | 0.294 | 0.1067 | No |
| 21 | H2-Aa | 2824 | 0.281 | 0.1056 | No |
| 22 | Acvr2a | 3086 | 0.264 | 0.0999 | No |
| 23 | Tap2 | 3398 | 0.244 | 0.0911 | No |
| 24 | Eif4g3 | 4055 | 0.215 | 0.0641 | No |
| 25 | Ly75 | 4068 | 0.215 | 0.0695 | No |
| 26 | Ccr5 | 4285 | 0.204 | 0.0644 | No |
| 27 | Galnt1 | 4639 | 0.188 | 0.0519 | No |
| 28 | Abce1 | 4770 | 0.182 | 0.0505 | No |
| 29 | Brca1 | 4859 | 0.178 | 0.0510 | No |
| 30 | Flna | 4923 | 0.175 | 0.0528 | No |
| 31 | Traf2 | 4960 | 0.174 | 0.0558 | No |
| 32 | Zap70 | 5046 | 0.170 | 0.0563 | No |
| 33 | Cd28 | 5120 | 0.167 | 0.0573 | No |
| 34 | Wars1 | 5311 | 0.157 | 0.0522 | No |
| 35 | Itgal | 5469 | 0.152 | 0.0485 | No |
| 36 | Il16 | 5496 | 0.151 | 0.0515 | No |
| 37 | Cd86 | 5584 | 0.147 | 0.0512 | No |
| 38 | Ets1 | 5780 | 0.137 | 0.0452 | No |
| 39 | Abi1 | 5872 | 0.133 | 0.0444 | No |
| 40 | Lcp2 | 6181 | 0.122 | 0.0323 | No |
| 41 | Tpd52 | 6366 | 0.114 | 0.0262 | No |
| 42 | Inhba | 6383 | 0.113 | 0.0286 | No |
| 43 | Fcgr2b | 6492 | 0.109 | 0.0262 | No |
| 44 | Tap1 | 6509 | 0.108 | 0.0285 | No |
| 45 | Map3k7 | 6809 | 0.097 | 0.0161 | No |
| 46 | Csf1 | 6957 | 0.092 | 0.0113 | No |
| 47 | Hcls1 | 7190 | 0.082 | 0.0020 | No |
| 48 | Mrpl3 | 7404 | 0.077 | -0.0066 | No |
| 49 | Socs5 | 7547 | 0.072 | -0.0117 | No |
| 50 | Cd80 | 7689 | 0.066 | -0.0170 | No |
| 51 | Bcl10 | 7822 | 0.061 | -0.0219 | No |
| 52 | Was | 7953 | 0.055 | -0.0269 | No |
| 53 | Bcl3 | 8065 | 0.052 | -0.0310 | No |
| 54 | Nck1 | 8308 | 0.042 | -0.0420 | No |
| 55 | Akt1 | 8501 | 0.035 | -0.0507 | No |
| 56 | Tlr2 | 8773 | 0.026 | -0.0636 | No |
| 57 | Eif3j1 | 8818 | 0.024 | -0.0652 | No |
| 58 | Capg | 9448 | 0.001 | -0.0968 | No |
| 59 | Il2 | 9490 | 0.000 | -0.0989 | No |
| 60 | Ube2n | 10309 | -0.026 | -0.1393 | No |
| 61 | H2-Ob | 10326 | -0.026 | -0.1393 | No |
| 62 | Il18 | 10351 | -0.027 | -0.1398 | No |
| 63 | Prkcb | 10370 | -0.028 | -0.1399 | No |
| 64 | Elf4 | 10488 | -0.032 | -0.1449 | No |
| 65 | Cfp | 10700 | -0.040 | -0.1544 | No |
| 66 | Hif1a | 10775 | -0.043 | -0.1569 | No |
| 67 | Irf4 | 11019 | -0.052 | -0.1677 | No |
| 68 | Ptprc | 11223 | -0.058 | -0.1763 | No |
| 69 | Rps3a1 | 11271 | -0.060 | -0.1769 | No |
| 70 | Map4k1 | 11323 | -0.062 | -0.1778 | No |
| 71 | Ikbkb | 11507 | -0.068 | -0.1851 | No |
| 72 | Il15 | 11752 | -0.078 | -0.1952 | No |
| 73 | Stab1 | 12100 | -0.090 | -0.2101 | No |
| 74 | F2r | 12120 | -0.091 | -0.2085 | No |
| 75 | Ncf4 | 12174 | -0.093 | -0.2086 | No |
| 76 | Tnf | 12224 | -0.095 | -0.2083 | No |
| 77 | Cd247 | 12272 | -0.097 | -0.2080 | No |
| 78 | Ccr2 | 12371 | -0.101 | -0.2101 | No |
| 79 | Lyn | 12372 | -0.101 | -0.2073 | No |
| 80 | Lck | 12684 | -0.114 | -0.2197 | No |
| 81 | Ube2d1 | 12759 | -0.117 | -0.2201 | No |
| 82 | Npm1 | 12766 | -0.117 | -0.2172 | No |
| 83 | Stat4 | 13100 | -0.128 | -0.2303 | No |
| 84 | Irf8 | 13703 | -0.150 | -0.2564 | No |
| 85 | Rpl9 | 13718 | -0.151 | -0.2529 | No |
| 86 | Spi1 | 13831 | -0.156 | -0.2541 | No |
| 87 | Cd96 | 13883 | -0.158 | -0.2522 | No |
| 88 | Cd47 | 13955 | -0.161 | -0.2513 | No |
| 89 | St8sia4 | 13986 | -0.163 | -0.2483 | No |
| 90 | Glmn | 14046 | -0.165 | -0.2466 | No |
| 91 | Degs1 | 14204 | -0.172 | -0.2497 | No |
| 92 | Tlr3 | 14220 | -0.172 | -0.2456 | No |
| 93 | Irf7 | 14309 | -0.175 | -0.2451 | No |
| 94 | Mtif2 | 14376 | -0.178 | -0.2434 | No |
| 95 | Tgfb2 | 14387 | -0.179 | -0.2389 | No |
| 96 | Psmb10 | 14512 | -0.184 | -0.2400 | No |
| 97 | Eif5a | 14746 | -0.193 | -0.2463 | No |
| 98 | Csk | 14882 | -0.200 | -0.2475 | No |
| 99 | Ccnd3 | 14901 | -0.201 | -0.2428 | No |
| 100 | Igsf6 | 15031 | -0.207 | -0.2435 | No |
| 101 | Eif3d | 15080 | -0.210 | -0.2400 | No |
| 102 | Icam1 | 15313 | -0.222 | -0.2455 | No |
| 103 | Ifngr2 | 15722 | -0.240 | -0.2592 | Yes |
| 104 | Ptpn6 | 15769 | -0.243 | -0.2548 | Yes |
| 105 | Srgn | 15884 | -0.249 | -0.2535 | Yes |
| 106 | Pf4 | 15942 | -0.251 | -0.2494 | Yes |
| 107 | Il4ra | 16029 | -0.255 | -0.2465 | Yes |
| 108 | Socs1 | 16103 | -0.259 | -0.2430 | Yes |
| 109 | Ifngr1 | 16159 | -0.262 | -0.2384 | Yes |
| 110 | Crtam | 16183 | -0.263 | -0.2322 | Yes |
| 111 | Prkcg | 16223 | -0.265 | -0.2267 | Yes |
| 112 | Icosl | 16356 | -0.274 | -0.2257 | Yes |
| 113 | Tlr1 | 16451 | -0.280 | -0.2225 | Yes |
| 114 | Ifnar2 | 16678 | -0.292 | -0.2257 | Yes |
| 115 | Ccnd2 | 16936 | -0.307 | -0.2301 | Yes |
| 116 | Il7 | 17011 | -0.311 | -0.2251 | Yes |
| 117 | Fgr | 17268 | -0.326 | -0.2288 | Yes |
| 118 | Tgfb1 | 17328 | -0.329 | -0.2225 | Yes |
| 119 | Il12rb1 | 17379 | -0.333 | -0.2157 | Yes |
| 120 | Itgb2 | 17454 | -0.337 | -0.2100 | Yes |
| 121 | Bcat1 | 17582 | -0.346 | -0.2067 | Yes |
| 122 | Il18rap | 17636 | -0.350 | -0.1996 | Yes |
| 123 | Itk | 17780 | -0.360 | -0.1967 | Yes |
| 124 | H2-Oa | 17809 | -0.363 | -0.1879 | Yes |
| 125 | Nme1 | 17932 | -0.374 | -0.1836 | Yes |
| 126 | Il12a | 18011 | -0.380 | -0.1768 | Yes |
| 127 | Hdac9 | 18117 | -0.390 | -0.1712 | Yes |
| 128 | Gcnt1 | 18196 | -0.397 | -0.1640 | Yes |
| 129 | Thy1 | 18574 | -0.434 | -0.1708 | Yes |
| 130 | H2-DMb2 | 18712 | -0.451 | -0.1650 | Yes |
| 131 | Trat1 | 18870 | -0.470 | -0.1597 | Yes |
| 132 | Elane | 19071 | -0.498 | -0.1558 | Yes |
| 133 | Rps9 | 19088 | -0.499 | -0.1426 | Yes |
| 134 | Il2rg | 19233 | -0.526 | -0.1352 | Yes |
| 135 | Ache | 19238 | -0.526 | -0.1206 | Yes |
| 136 | Fas | 19313 | -0.541 | -0.1092 | Yes |
| 137 | B2m | 19493 | -0.582 | -0.1019 | Yes |
| 138 | Il27ra | 19504 | -0.584 | -0.0860 | Yes |
| 139 | Il11 | 19636 | -0.624 | -0.0751 | Yes |
| 140 | H2-DMa | 19677 | -0.636 | -0.0593 | Yes |
| 141 | Cd40 | 19682 | -0.638 | -0.0416 | Yes |
| 142 | Gpr65 | 19730 | -0.655 | -0.0256 | Yes |
| 143 | C2 | 19832 | -0.715 | -0.0107 | Yes |
| 144 | Ccr1 | 19845 | -0.727 | 0.0091 | Yes |

