Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	GMP.GMP.neu_Pheno.cls #Group1_versus_Group2.GMP.neu_Pheno.cls #Group1_versus_Group2_repos
Phenotype	GMP.neu_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.31230143
Normalized Enrichment Score (NES)	-1.6306797
Nominal p-value	0.0
FDR q-value	0.1345492
FWER p-Value	0.178

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Il4	376	0.700	0.0126	No
2	Fgf22	627	0.616	0.0277	No
3	Prkaa2	1148	0.512	0.0246	No
4	Prkcb	1568	0.461	0.0243	No
5	Egfr	1989	0.412	0.0218	No
6	Adcy2	2539	0.369	0.0108	No
7	Sfn	2723	0.356	0.0176	No
8	Itpr2	2958	0.337	0.0210	No
9	Grk2	4039	0.265	-0.0213	No
10	Cxcr4	4054	0.265	-0.0101	No
11	Rit1	4251	0.252	-0.0086	No
12	Plcg1	4260	0.252	0.0023	No
13	Map2k6	4581	0.235	-0.0032	No
14	Slc2a1	5153	0.209	-0.0225	No
15	E2f1	5313	0.202	-0.0214	No
16	Irak4	5422	0.196	-0.0180	No
17	Raf1	5852	0.173	-0.0318	No
18	Nod1	6065	0.163	-0.0351	No
19	Tiam1	6134	0.161	-0.0313	No
20	Cab39l	6508	0.145	-0.0435	No
21	Csnk2b	6551	0.144	-0.0391	No
22	Ppp2r1b	6925	0.128	-0.0521	No
23	Pak4	6948	0.127	-0.0475	No
24	Vav3	6974	0.126	-0.0431	No
25	Mknk1	7216	0.116	-0.0500	No
26	Akt1s1	7330	0.111	-0.0507	No
27	Cdk1	7655	0.097	-0.0626	No
28	Nfkbib	7759	0.093	-0.0636	No
29	Camk4	7863	0.089	-0.0647	No
30	Rptor	7943	0.086	-0.0649	No
31	Map3k7	8443	0.066	-0.0869	No
32	Prkar2a	8604	0.061	-0.0922	No
33	Dapp1	9058	0.043	-0.1130	No
34	Stat2	9937	0.010	-0.1566	No
35	Pin1	10037	0.007	-0.1613	No
36	Ywhab	10211	0.001	-0.1699	No
37	Rps6ka1	10444	-0.005	-0.1813	No
38	Grb2	10503	-0.007	-0.1839	No
39	Pten	10867	-0.021	-0.2012	No
40	Tsc2	10950	-0.023	-0.2043	No
41	Mapk1	11312	-0.036	-0.2208	No
42	Pikfyve	11358	-0.038	-0.2214	No
43	Cab39	11657	-0.047	-0.2342	No
44	Traf2	11829	-0.054	-0.2403	No
45	Ptpn11	11917	-0.057	-0.2422	No
46	Ripk1	12071	-0.062	-0.2471	No
47	Smad2	12094	-0.063	-0.2453	No
48	Tbk1	12238	-0.068	-0.2495	No
49	Ddit3	12250	-0.068	-0.2469	No
50	Mapk8	12275	-0.069	-0.2450	No
51	Trib3	12350	-0.072	-0.2455	No
52	Dusp3	12602	-0.082	-0.2544	No
53	Mapkap1	12656	-0.084	-0.2533	No
54	Mapk9	12812	-0.090	-0.2571	No
55	Nck1	13263	-0.106	-0.2749	No
56	Pfn1	13307	-0.107	-0.2722	No
57	Pik3r3	13325	-0.108	-0.2682	No
58	Cdk4	13759	-0.123	-0.2845	No
59	Mknk2	13841	-0.126	-0.2829	No
60	Them4	14073	-0.135	-0.2884	No
61	Gsk3b	14091	-0.136	-0.2831	No
62	Eif4e	14158	-0.139	-0.2802	No
63	Arhgdia	14232	-0.142	-0.2775	No
64	Tnfrsf1a	14361	-0.147	-0.2773	No
65	Gna14	14525	-0.153	-0.2786	No
66	Pla2g12a	14673	-0.160	-0.2788	No
67	Actr3	15341	-0.188	-0.3039	Yes
68	Cdkn1a	15413	-0.189	-0.2989	Yes
69	Pdk1	15584	-0.196	-0.2986	Yes
70	Prkag1	15672	-0.200	-0.2940	Yes
71	Ube2n	15747	-0.203	-0.2886	Yes
72	Map2k3	15755	-0.203	-0.2798	Yes
73	Atf1	16021	-0.216	-0.2834	Yes
74	Il2rg	16027	-0.216	-0.2740	Yes
75	Cdk2	16050	-0.217	-0.2653	Yes
76	Cltc	16062	-0.218	-0.2561	Yes
77	Ecsit	16337	-0.232	-0.2594	Yes
78	Acaca	16848	-0.258	-0.2734	Yes
79	Ube2d3	17026	-0.268	-0.2702	Yes
80	Arpc3	17181	-0.276	-0.2656	Yes
81	Rac1	17212	-0.278	-0.2546	Yes
82	Actr2	17243	-0.280	-0.2435	Yes
83	Sla	17409	-0.290	-0.2388	Yes
84	Sqstm1	17979	-0.329	-0.2525	Yes
85	Calr	18093	-0.337	-0.2430	Yes
86	Ap2m1	18373	-0.361	-0.2408	Yes
87	Mapk10	18559	-0.379	-0.2331	Yes
88	Cfl1	18869	-0.411	-0.2301	Yes
89	Akt1	19183	-0.448	-0.2257	Yes
90	Lck	19233	-0.456	-0.2077	Yes
91	Plcb1	19238	-0.457	-0.1873	Yes
92	Cdkn1b	19306	-0.468	-0.1697	Yes
93	Arf1	19401	-0.485	-0.1526	Yes
94	Hsp90b1	19466	-0.500	-0.1334	Yes
95	Ralb	19495	-0.508	-0.1119	Yes
96	Ppp1ca	19543	-0.521	-0.0909	Yes
97	Hras	19600	-0.538	-0.0695	Yes
98	Rps6ka3	19911	-0.688	-0.0542	Yes
99	Myd88	20020	-1.333	0.0003	Yes