| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group2.GMP.neu_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.4747319 |
| Normalized Enrichment Score (NES) | -1.6082873 |
| Nominal p-value | 0.06378601 |
| FDR q-value | 0.11762169 |
| FWER p-Value | 0.2 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc2a3 | 676 | 0.605 | -0.0197 | No |
| 2 | Niban1 | 1420 | 0.477 | -0.0458 | No |
| 3 | Ppp1r15a | 2029 | 0.410 | -0.0667 | No |
| 4 | Eef1e1 | 3124 | 0.325 | -0.1141 | No |
| 5 | Plod2 | 3972 | 0.268 | -0.1504 | No |
| 6 | Cd9 | 4011 | 0.266 | -0.1459 | No |
| 7 | Cxcr4 | 4054 | 0.265 | -0.1417 | No |
| 8 | Rit1 | 4251 | 0.252 | -0.1456 | No |
| 9 | Psph | 4372 | 0.247 | -0.1458 | No |
| 10 | Glrx | 4666 | 0.232 | -0.1550 | No |
| 11 | Hk2 | 5001 | 0.217 | -0.1667 | No |
| 12 | Slc2a1 | 5153 | 0.209 | -0.1693 | No |
| 13 | Pgm1 | 5476 | 0.192 | -0.1810 | No |
| 14 | Ak4 | 5505 | 0.191 | -0.1778 | No |
| 15 | Add3 | 5527 | 0.190 | -0.1744 | No |
| 16 | Tubg1 | 5823 | 0.174 | -0.1851 | No |
| 17 | Hmbs | 5991 | 0.166 | -0.1895 | No |
| 18 | Itgb2 | 6091 | 0.162 | -0.1907 | No |
| 19 | Pgk1 | 6092 | 0.162 | -0.1868 | No |
| 20 | Lta4h | 6152 | 0.160 | -0.1860 | No |
| 21 | Elovl6 | 6279 | 0.155 | -0.1887 | No |
| 22 | Rdh11 | 6712 | 0.137 | -0.2072 | No |
| 23 | Rrp9 | 6778 | 0.134 | -0.2073 | No |
| 24 | Dhfr | 6999 | 0.125 | -0.2154 | No |
| 25 | Slc1a4 | 7092 | 0.121 | -0.2171 | No |
| 26 | Rpa1 | 7189 | 0.117 | -0.2192 | No |
| 27 | Nampt | 7396 | 0.107 | -0.2270 | No |
| 28 | Tes | 7544 | 0.101 | -0.2320 | No |
| 29 | Nfkbib | 7759 | 0.093 | -0.2406 | No |
| 30 | Fgl2 | 7999 | 0.083 | -0.2507 | No |
| 31 | G6pdx | 8010 | 0.082 | -0.2492 | No |
| 32 | Dhcr7 | 8059 | 0.081 | -0.2497 | No |
| 33 | Egln3 | 8364 | 0.069 | -0.2634 | No |
| 34 | Tpi1 | 8523 | 0.064 | -0.2698 | No |
| 35 | Plk1 | 8705 | 0.057 | -0.2776 | No |
| 36 | Ctsc | 8834 | 0.052 | -0.2828 | No |
| 37 | Dapp1 | 9058 | 0.043 | -0.2930 | No |
| 38 | Psmg1 | 9100 | 0.041 | -0.2941 | No |
| 39 | Hmgcr | 9368 | 0.031 | -0.3068 | No |
| 40 | Ebp | 9499 | 0.026 | -0.3128 | No |
| 41 | Polr3g | 9509 | 0.026 | -0.3126 | No |
| 42 | Gsr | 9601 | 0.022 | -0.3167 | No |
| 43 | Mllt11 | 9623 | 0.022 | -0.3172 | No |
| 44 | Gbe1 | 9719 | 0.019 | -0.3215 | No |
| 45 | Stard4 | 10049 | 0.007 | -0.3380 | No |
| 46 | Qdpr | 10526 | -0.008 | -0.3618 | No |
| 47 | Ccng1 | 10825 | -0.019 | -0.3764 | No |
| 48 | Fdxr | 10841 | -0.019 | -0.3766 | No |
| 49 | Wars1 | 10904 | -0.021 | -0.3793 | No |
| 50 | Elovl5 | 11007 | -0.025 | -0.3838 | No |
| 51 | Btg2 | 11063 | -0.026 | -0.3860 | No |
| 52 | Psmd13 | 11068 | -0.027 | -0.3855 | No |
| 53 | Idi1 | 11320 | -0.036 | -0.3973 | No |
| 54 | Gga2 | 11492 | -0.042 | -0.4049 | No |
| 55 | Dhcr24 | 11581 | -0.045 | -0.4083 | No |
| 56 | Pitpnb | 11603 | -0.045 | -0.4083 | No |
| 57 | Gmps | 11639 | -0.047 | -0.4090 | No |
| 58 | Adipor2 | 11741 | -0.051 | -0.4128 | No |
| 59 | Psmb5 | 11757 | -0.052 | -0.4123 | No |
| 60 | Pfkl | 11771 | -0.052 | -0.4118 | No |
| 61 | Tmem97 | 12134 | -0.064 | -0.4285 | No |
| 62 | Tbk1 | 12238 | -0.068 | -0.4321 | No |
| 63 | Psme3 | 12242 | -0.068 | -0.4306 | No |
| 64 | Ddit3 | 12250 | -0.068 | -0.4293 | No |
| 65 | Eno1b | 12304 | -0.071 | -0.4303 | No |
| 66 | Trib3 | 12350 | -0.072 | -0.4308 | No |
| 67 | Tcea1 | 12447 | -0.076 | -0.4339 | No |
| 68 | Nufip1 | 12463 | -0.077 | -0.4328 | No |
| 69 | Pno1 | 12657 | -0.084 | -0.4405 | No |
| 70 | Arpc5l | 12671 | -0.084 | -0.4392 | No |
| 71 | Tuba4a | 12692 | -0.085 | -0.4381 | No |
| 72 | Pdap1 | 12743 | -0.087 | -0.4386 | No |
| 73 | Ldlr | 12795 | -0.089 | -0.4390 | No |
| 74 | Mcm4 | 12905 | -0.092 | -0.4423 | No |
| 75 | Nmt1 | 13015 | -0.097 | -0.4455 | No |
| 76 | Acly | 13229 | -0.105 | -0.4538 | No |
| 77 | Pik3r3 | 13325 | -0.108 | -0.4560 | No |
| 78 | Cdc25a | 13341 | -0.108 | -0.4542 | No |
| 79 | Tm7sf2 | 13370 | -0.110 | -0.4530 | No |
| 80 | Nfyc | 13406 | -0.110 | -0.4521 | No |
| 81 | Srd5a1 | 13461 | -0.112 | -0.4522 | No |
| 82 | Etf1 | 13467 | -0.112 | -0.4498 | No |
| 83 | Immt | 13505 | -0.114 | -0.4489 | No |
| 84 | Sord | 13530 | -0.114 | -0.4474 | No |
| 85 | Phgdh | 13555 | -0.115 | -0.4459 | No |
| 86 | Mthfd2 | 13778 | -0.124 | -0.4541 | No |
| 87 | Gclc | 13818 | -0.125 | -0.4531 | No |
| 88 | Slc37a4 | 13854 | -0.127 | -0.4519 | No |
| 89 | Ccnf | 13945 | -0.130 | -0.4533 | No |
| 90 | Ifrd1 | 13964 | -0.131 | -0.4511 | No |
| 91 | Psmc2 | 13983 | -0.132 | -0.4488 | No |
| 92 | Gsk3b | 14091 | -0.136 | -0.4510 | No |
| 93 | Stip1 | 14167 | -0.139 | -0.4515 | No |
| 94 | Sqle | 14330 | -0.145 | -0.4562 | No |
| 95 | Fkbp2 | 14389 | -0.148 | -0.4556 | No |
| 96 | Hspa4 | 14770 | -0.164 | -0.4708 | Yes |
| 97 | Psat1 | 14835 | -0.167 | -0.4701 | Yes |
| 98 | Mthfd2l | 14865 | -0.168 | -0.4675 | Yes |
| 99 | Cyb5b | 14880 | -0.169 | -0.4642 | Yes |
| 100 | Cth | 14884 | -0.169 | -0.4604 | Yes |
| 101 | M6pr | 14980 | -0.173 | -0.4610 | Yes |
| 102 | Cct6a | 15095 | -0.177 | -0.4626 | Yes |
| 103 | Ero1a | 15285 | -0.185 | -0.4677 | Yes |
| 104 | Tomm40 | 15308 | -0.186 | -0.4643 | Yes |
| 105 | Atp2a2 | 15313 | -0.187 | -0.4601 | Yes |
| 106 | Actr3 | 15341 | -0.188 | -0.4570 | Yes |
| 107 | Cdkn1a | 15413 | -0.189 | -0.4561 | Yes |
| 108 | Psma4 | 15489 | -0.192 | -0.4553 | Yes |
| 109 | Hmgcs1 | 15494 | -0.192 | -0.4509 | Yes |
| 110 | Psmc6 | 15525 | -0.193 | -0.4478 | Yes |
| 111 | Gpi1 | 15531 | -0.194 | -0.4434 | Yes |
| 112 | Pdk1 | 15584 | -0.196 | -0.4414 | Yes |
| 113 | Slc1a5 | 15627 | -0.198 | -0.4388 | Yes |
| 114 | Bub1 | 15630 | -0.198 | -0.4342 | Yes |
| 115 | Ppia | 15710 | -0.202 | -0.4333 | Yes |
| 116 | Nup205 | 15729 | -0.202 | -0.4294 | Yes |
| 117 | Map2k3 | 15755 | -0.203 | -0.4258 | Yes |
| 118 | Nupr1 | 15841 | -0.207 | -0.4252 | Yes |
| 119 | Uchl5 | 15859 | -0.208 | -0.4211 | Yes |
| 120 | Ppa1 | 16203 | -0.225 | -0.4330 | Yes |
| 121 | Gla | 16284 | -0.229 | -0.4316 | Yes |
| 122 | Prdx1 | 16309 | -0.231 | -0.4273 | Yes |
| 123 | Skap2 | 16377 | -0.235 | -0.4251 | Yes |
| 124 | Ifi30 | 16422 | -0.237 | -0.4217 | Yes |
| 125 | Atp6v1d | 16446 | -0.238 | -0.4172 | Yes |
| 126 | Mcm2 | 16576 | -0.243 | -0.4179 | Yes |
| 127 | Aurka | 16713 | -0.251 | -0.4188 | Yes |
| 128 | Gtf2h1 | 16780 | -0.254 | -0.4161 | Yes |
| 129 | Insig1 | 16788 | -0.254 | -0.4103 | Yes |
| 130 | Sdf2l1 | 16828 | -0.257 | -0.4062 | Yes |
| 131 | Ykt6 | 16841 | -0.258 | -0.4007 | Yes |
| 132 | Vldlr | 16843 | -0.258 | -0.3946 | Yes |
| 133 | Acaca | 16848 | -0.258 | -0.3886 | Yes |
| 134 | Ube2d3 | 17026 | -0.268 | -0.3912 | Yes |
| 135 | Actr2 | 17243 | -0.280 | -0.3954 | Yes |
| 136 | Txnrd1 | 17247 | -0.280 | -0.3889 | Yes |
| 137 | Sla | 17409 | -0.290 | -0.3901 | Yes |
| 138 | Idh1 | 17515 | -0.296 | -0.3883 | Yes |
| 139 | Canx | 17520 | -0.297 | -0.3814 | Yes |
| 140 | Ddx39a | 17662 | -0.308 | -0.3812 | Yes |
| 141 | Eif2s2 | 17705 | -0.310 | -0.3759 | Yes |
| 142 | Slc7a11 | 17728 | -0.312 | -0.3696 | Yes |
| 143 | Rab1a | 17730 | -0.312 | -0.3622 | Yes |
| 144 | Cyp51 | 17731 | -0.312 | -0.3548 | Yes |
| 145 | Psmd14 | 17736 | -0.312 | -0.3475 | Yes |
| 146 | Psmd12 | 17766 | -0.314 | -0.3415 | Yes |
| 147 | Lgmn | 17769 | -0.315 | -0.3341 | Yes |
| 148 | Fads2 | 17770 | -0.315 | -0.3266 | Yes |
| 149 | Me1 | 17827 | -0.319 | -0.3218 | Yes |
| 150 | Coro1a | 17832 | -0.319 | -0.3144 | Yes |
| 151 | Uso1 | 17844 | -0.320 | -0.3074 | Yes |
| 152 | Slc6a6 | 17895 | -0.323 | -0.3022 | Yes |
| 153 | Shmt2 | 17933 | -0.326 | -0.2963 | Yes |
| 154 | Ung | 17941 | -0.327 | -0.2888 | Yes |
| 155 | Cacybp | 17970 | -0.329 | -0.2824 | Yes |
| 156 | Sqstm1 | 17979 | -0.329 | -0.2750 | Yes |
| 157 | Sec11a | 18003 | -0.331 | -0.2683 | Yes |
| 158 | Cfp | 18036 | -0.333 | -0.2619 | Yes |
| 159 | Calr | 18093 | -0.337 | -0.2567 | Yes |
| 160 | Tfrc | 18104 | -0.338 | -0.2492 | Yes |
| 161 | Aldoa | 18110 | -0.338 | -0.2414 | Yes |
| 162 | Sytl2 | 18151 | -0.342 | -0.2353 | Yes |
| 163 | Hspa9 | 18298 | -0.354 | -0.2342 | Yes |
| 164 | Serp1 | 18316 | -0.355 | -0.2266 | Yes |
| 165 | Sc5d | 18326 | -0.356 | -0.2186 | Yes |
| 166 | Hspd1 | 18337 | -0.357 | -0.2106 | Yes |
| 167 | Slc7a5 | 18348 | -0.358 | -0.2026 | Yes |
| 168 | Cops5 | 18392 | -0.362 | -0.1961 | Yes |
| 169 | Hspe1 | 18425 | -0.366 | -0.1890 | Yes |
| 170 | Ufm1 | 18446 | -0.368 | -0.1812 | Yes |
| 171 | Psmc4 | 18497 | -0.372 | -0.1749 | Yes |
| 172 | Edem1 | 18580 | -0.380 | -0.1699 | Yes |
| 173 | Acsl3 | 18792 | -0.404 | -0.1710 | Yes |
| 174 | Fads1 | 18907 | -0.416 | -0.1668 | Yes |
| 175 | P4ha1 | 19004 | -0.427 | -0.1615 | Yes |
| 176 | Nfil3 | 19041 | -0.431 | -0.1530 | Yes |
| 177 | Got1 | 19086 | -0.436 | -0.1449 | Yes |
| 178 | Psma3 | 19274 | -0.464 | -0.1432 | Yes |
| 179 | Rrm2 | 19292 | -0.466 | -0.1330 | Yes |
| 180 | Ldha | 19331 | -0.472 | -0.1237 | Yes |
| 181 | Pnp | 19409 | -0.488 | -0.1159 | Yes |
| 182 | Hsp90b1 | 19466 | -0.500 | -0.1068 | Yes |
| 183 | Bhlhe40 | 19475 | -0.502 | -0.0953 | Yes |
| 184 | Abcf2 | 19647 | -0.549 | -0.0908 | Yes |
| 185 | Hspa5 | 19713 | -0.571 | -0.0805 | Yes |
| 186 | Rpn1 | 19723 | -0.574 | -0.0673 | Yes |
| 187 | Ssr1 | 19759 | -0.584 | -0.0551 | Yes |
| 188 | Ddit4 | 19775 | -0.595 | -0.0417 | Yes |
| 189 | Bcat1 | 19781 | -0.598 | -0.0277 | Yes |
| 190 | Xbp1 | 19854 | -0.641 | -0.0161 | Yes |
| 191 | Asns | 20013 | -1.036 | 0.0007 | Yes |

