| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group2.GMP.neu_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | -0.32779858 |
| Normalized Enrichment Score (NES) | -1.6441226 |
| Nominal p-value | 0.073076926 |
| FDR q-value | 0.18098097 |
| FWER p-Value | 0.163 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccnd1 | 461 | 0.663 | -0.0006 | No |
| 2 | Slc12a2 | 514 | 0.648 | 0.0189 | No |
| 3 | Pttg1 | 1170 | 0.508 | 0.0032 | No |
| 4 | Katna1 | 2023 | 0.410 | -0.0258 | No |
| 5 | Srsf10 | 3991 | 0.267 | -0.1158 | No |
| 6 | Marcks | 4409 | 0.245 | -0.1285 | No |
| 7 | Tle3 | 4541 | 0.238 | -0.1270 | No |
| 8 | Cdkn3 | 5083 | 0.213 | -0.1470 | No |
| 9 | Pole | 5254 | 0.204 | -0.1486 | No |
| 10 | E2f1 | 5313 | 0.202 | -0.1446 | No |
| 11 | Kif2c | 5648 | 0.183 | -0.1552 | No |
| 12 | Cdc45 | 5671 | 0.182 | -0.1501 | No |
| 13 | Pds5b | 5718 | 0.180 | -0.1463 | No |
| 14 | Rps6ka5 | 5929 | 0.170 | -0.1511 | No |
| 15 | Cbx1 | 5938 | 0.169 | -0.1457 | No |
| 16 | Dtymk | 5975 | 0.167 | -0.1418 | No |
| 17 | Nup50 | 5998 | 0.166 | -0.1373 | No |
| 18 | Cdc20 | 6138 | 0.160 | -0.1388 | No |
| 19 | Ezh2 | 6481 | 0.146 | -0.1511 | No |
| 20 | Fancc | 6566 | 0.143 | -0.1504 | No |
| 21 | Aurkb | 6694 | 0.138 | -0.1521 | No |
| 22 | Orc5 | 6754 | 0.135 | -0.1505 | No |
| 23 | Tra2b | 6987 | 0.126 | -0.1579 | No |
| 24 | Pola2 | 7282 | 0.113 | -0.1688 | No |
| 25 | Kif22 | 7298 | 0.113 | -0.1657 | No |
| 26 | Hnrnpd | 7325 | 0.111 | -0.1633 | No |
| 27 | Kif23 | 7419 | 0.107 | -0.1643 | No |
| 28 | Numa1 | 7556 | 0.101 | -0.1677 | No |
| 29 | Mnat1 | 7576 | 0.100 | -0.1653 | No |
| 30 | Cdk1 | 7655 | 0.097 | -0.1659 | No |
| 31 | Tfdp1 | 7677 | 0.096 | -0.1637 | No |
| 32 | Exo1 | 7830 | 0.090 | -0.1683 | No |
| 33 | Abl1 | 7957 | 0.085 | -0.1717 | No |
| 34 | Stmn1 | 8026 | 0.082 | -0.1723 | No |
| 35 | Prim2 | 8036 | 0.082 | -0.1700 | No |
| 36 | Fbxo5 | 8058 | 0.081 | -0.1683 | No |
| 37 | Brca2 | 8113 | 0.079 | -0.1683 | No |
| 38 | Map3k20 | 8309 | 0.071 | -0.1758 | No |
| 39 | Chmp1a | 8328 | 0.070 | -0.1743 | No |
| 40 | Ewsr1 | 8385 | 0.069 | -0.1748 | No |
| 41 | Ilf3 | 8687 | 0.058 | -0.1880 | No |
| 42 | Plk1 | 8705 | 0.057 | -0.1869 | No |
| 43 | Suv39h1 | 8713 | 0.057 | -0.1853 | No |
| 44 | Smad3 | 8767 | 0.054 | -0.1861 | No |
| 45 | Foxn3 | 8787 | 0.054 | -0.1852 | No |
| 46 | Ube2s | 9234 | 0.036 | -0.2065 | No |
| 47 | Rasal2 | 9439 | 0.028 | -0.2158 | No |
| 48 | Rpa2 | 9484 | 0.026 | -0.2171 | No |
| 49 | E2f3 | 9540 | 0.025 | -0.2191 | No |
| 50 | Espl1 | 9556 | 0.024 | -0.2190 | No |
| 51 | Rad21 | 9576 | 0.023 | -0.2192 | No |
| 52 | Dmd | 9731 | 0.018 | -0.2263 | No |
| 53 | Srsf2 | 9802 | 0.015 | -0.2293 | No |
| 54 | Atrx | 9806 | 0.015 | -0.2290 | No |
| 55 | Arid4a | 9854 | 0.013 | -0.2309 | No |
| 56 | Chaf1a | 10030 | 0.007 | -0.2395 | No |
| 57 | Cul5 | 10038 | 0.007 | -0.2396 | No |
| 58 | Hmgb3 | 10077 | 0.006 | -0.2413 | No |
| 59 | Ccna2 | 10178 | 0.002 | -0.2462 | No |
| 60 | Meis1 | 10215 | 0.001 | -0.2480 | No |
| 61 | Chek1 | 10224 | 0.001 | -0.2484 | No |
| 62 | Orc6 | 10233 | 0.001 | -0.2488 | No |
| 63 | Ctcf | 10372 | -0.003 | -0.2556 | No |
| 64 | Mapk14 | 10385 | -0.004 | -0.2561 | No |
| 65 | Uck2 | 10472 | -0.006 | -0.2603 | No |
| 66 | Prpf4b | 10479 | -0.006 | -0.2604 | No |
| 67 | Smarcc1 | 10511 | -0.007 | -0.2617 | No |
| 68 | H2az2 | 10542 | -0.008 | -0.2629 | No |
| 69 | Knl1 | 10743 | -0.016 | -0.2725 | No |
| 70 | Ythdc1 | 10858 | -0.020 | -0.2775 | No |
| 71 | Polq | 10916 | -0.022 | -0.2796 | No |
| 72 | Cul4a | 10951 | -0.023 | -0.2806 | No |
| 73 | E2f2 | 10982 | -0.024 | -0.2813 | No |
| 74 | Stag1 | 10997 | -0.024 | -0.2812 | No |
| 75 | Slc38a1 | 11026 | -0.025 | -0.2817 | No |
| 76 | Stil | 11079 | -0.027 | -0.2834 | No |
| 77 | Traip | 11153 | -0.030 | -0.2861 | No |
| 78 | Pml | 11329 | -0.037 | -0.2937 | No |
| 79 | Mcm6 | 11366 | -0.038 | -0.2942 | No |
| 80 | Notch2 | 11441 | -0.040 | -0.2965 | No |
| 81 | Incenp | 11505 | -0.042 | -0.2983 | No |
| 82 | H2ax | 11548 | -0.043 | -0.2989 | No |
| 83 | Cul3 | 11690 | -0.049 | -0.3044 | No |
| 84 | Pbk | 11802 | -0.053 | -0.3081 | No |
| 85 | Ss18 | 11816 | -0.054 | -0.3070 | No |
| 86 | Birc5 | 11911 | -0.057 | -0.3098 | No |
| 87 | Rbl1 | 11920 | -0.057 | -0.3082 | No |
| 88 | Mcm5 | 12068 | -0.062 | -0.3135 | No |
| 89 | Lmnb1 | 12070 | -0.062 | -0.3115 | No |
| 90 | Mtf2 | 12102 | -0.063 | -0.3109 | No |
| 91 | Bard1 | 12174 | -0.066 | -0.3122 | No |
| 92 | Cenpf | 12177 | -0.066 | -0.3101 | No |
| 93 | Syncrip | 12255 | -0.069 | -0.3116 | No |
| 94 | Smc2 | 12382 | -0.073 | -0.3155 | No |
| 95 | Top2a | 12399 | -0.074 | -0.3138 | No |
| 96 | Hus1 | 12410 | -0.075 | -0.3117 | No |
| 97 | Pura | 12417 | -0.075 | -0.3095 | No |
| 98 | Efna5 | 12454 | -0.076 | -0.3087 | No |
| 99 | Nsd2 | 12457 | -0.076 | -0.3062 | No |
| 100 | Smc4 | 12770 | -0.088 | -0.3189 | No |
| 101 | Tmpo | 12814 | -0.090 | -0.3180 | No |
| 102 | Dkc1 | 12975 | -0.095 | -0.3228 | No |
| 103 | Slc7a1 | 13075 | -0.099 | -0.3244 | Yes |
| 104 | Bub3 | 13080 | -0.099 | -0.3212 | Yes |
| 105 | Tent4a | 13082 | -0.099 | -0.3179 | Yes |
| 106 | Mad2l1 | 13108 | -0.100 | -0.3157 | Yes |
| 107 | Cul1 | 13192 | -0.103 | -0.3164 | Yes |
| 108 | Cdc25b | 13252 | -0.105 | -0.3157 | Yes |
| 109 | Lig3 | 13337 | -0.108 | -0.3163 | Yes |
| 110 | Cdc25a | 13341 | -0.108 | -0.3127 | Yes |
| 111 | Nasp | 13590 | -0.117 | -0.3213 | Yes |
| 112 | Smc1a | 13612 | -0.118 | -0.3183 | Yes |
| 113 | Top1 | 13720 | -0.122 | -0.3195 | Yes |
| 114 | Mcm3 | 13727 | -0.122 | -0.3157 | Yes |
| 115 | Sfpq | 13730 | -0.122 | -0.3116 | Yes |
| 116 | Cdk4 | 13759 | -0.123 | -0.3088 | Yes |
| 117 | Hira | 13834 | -0.126 | -0.3083 | Yes |
| 118 | Tacc3 | 13857 | -0.127 | -0.3051 | Yes |
| 119 | Ccnf | 13945 | -0.130 | -0.3050 | Yes |
| 120 | Tgfb1 | 13958 | -0.131 | -0.3012 | Yes |
| 121 | Xpo1 | 13987 | -0.132 | -0.2981 | Yes |
| 122 | Odf2 | 14003 | -0.132 | -0.2943 | Yes |
| 123 | Kif5b | 14026 | -0.133 | -0.2909 | Yes |
| 124 | Prc1 | 14043 | -0.134 | -0.2871 | Yes |
| 125 | Mybl2 | 14046 | -0.134 | -0.2826 | Yes |
| 126 | Ccnb2 | 14071 | -0.135 | -0.2792 | Yes |
| 127 | Ube2c | 14092 | -0.136 | -0.2756 | Yes |
| 128 | Kif15 | 14136 | -0.138 | -0.2730 | Yes |
| 129 | Ttk | 14144 | -0.138 | -0.2687 | Yes |
| 130 | Hnrnpu | 14179 | -0.140 | -0.2656 | Yes |
| 131 | Pafah1b1 | 14278 | -0.143 | -0.2657 | Yes |
| 132 | Dr1 | 14308 | -0.144 | -0.2622 | Yes |
| 133 | Sqle | 14330 | -0.145 | -0.2583 | Yes |
| 134 | Troap | 14386 | -0.148 | -0.2560 | Yes |
| 135 | Rad54l | 14498 | -0.152 | -0.2565 | Yes |
| 136 | Gspt1 | 14517 | -0.153 | -0.2522 | Yes |
| 137 | Rad23b | 14597 | -0.156 | -0.2508 | Yes |
| 138 | Kif20b | 14693 | -0.160 | -0.2501 | Yes |
| 139 | Casp8ap2 | 14703 | -0.161 | -0.2451 | Yes |
| 140 | Nup98 | 14717 | -0.161 | -0.2402 | Yes |
| 141 | Hif1a | 14778 | -0.164 | -0.2377 | Yes |
| 142 | Gins2 | 14908 | -0.170 | -0.2384 | Yes |
| 143 | Wrn | 14918 | -0.170 | -0.2330 | Yes |
| 144 | H2az1 | 14988 | -0.173 | -0.2306 | Yes |
| 145 | Kmt5a | 15008 | -0.173 | -0.2256 | Yes |
| 146 | Hmga1b | 15041 | -0.175 | -0.2213 | Yes |
| 147 | Myc | 15084 | -0.176 | -0.2174 | Yes |
| 148 | Cdc7 | 15121 | -0.178 | -0.2131 | Yes |
| 149 | Cks2 | 15241 | -0.183 | -0.2129 | Yes |
| 150 | Mki67 | 15349 | -0.188 | -0.2118 | Yes |
| 151 | Kif11 | 15473 | -0.191 | -0.2115 | Yes |
| 152 | Prmt5 | 15560 | -0.195 | -0.2092 | Yes |
| 153 | Lbr | 15568 | -0.195 | -0.2029 | Yes |
| 154 | Bub1 | 15630 | -0.198 | -0.1992 | Yes |
| 155 | H2bc12 | 15666 | -0.200 | -0.1941 | Yes |
| 156 | Egf | 15861 | -0.208 | -0.1968 | Yes |
| 157 | Cenpa | 15952 | -0.212 | -0.1941 | Yes |
| 158 | Kpnb1 | 15977 | -0.213 | -0.1880 | Yes |
| 159 | Cdc27 | 16000 | -0.214 | -0.1818 | Yes |
| 160 | Ncl | 16028 | -0.216 | -0.1758 | Yes |
| 161 | Tpx2 | 16040 | -0.217 | -0.1690 | Yes |
| 162 | Nusap1 | 16084 | -0.219 | -0.1637 | Yes |
| 163 | Odc1 | 16114 | -0.221 | -0.1576 | Yes |
| 164 | Plk4 | 16128 | -0.221 | -0.1507 | Yes |
| 165 | Tnpo2 | 16306 | -0.230 | -0.1517 | Yes |
| 166 | Kif4 | 16402 | -0.236 | -0.1485 | Yes |
| 167 | Cenpe | 16469 | -0.239 | -0.1437 | Yes |
| 168 | Ccnt1 | 16494 | -0.240 | -0.1367 | Yes |
| 169 | Mcm2 | 16576 | -0.243 | -0.1325 | Yes |
| 170 | Upf1 | 16708 | -0.250 | -0.1305 | Yes |
| 171 | Aurka | 16713 | -0.251 | -0.1222 | Yes |
| 172 | G3bp1 | 16716 | -0.251 | -0.1137 | Yes |
| 173 | Ndc80 | 16846 | -0.258 | -0.1114 | Yes |
| 174 | Amd1 | 16850 | -0.258 | -0.1028 | Yes |
| 175 | Cdkn2c | 16883 | -0.260 | -0.0955 | Yes |
| 176 | Nolc1 | 16920 | -0.262 | -0.0884 | Yes |
| 177 | Dbf4 | 17020 | -0.268 | -0.0842 | Yes |
| 178 | E2f4 | 17161 | -0.275 | -0.0819 | Yes |
| 179 | Cks1b | 17253 | -0.281 | -0.0769 | Yes |
| 180 | Nek2 | 17613 | -0.305 | -0.0846 | Yes |
| 181 | Ddx39a | 17662 | -0.308 | -0.0765 | Yes |
| 182 | Sap30 | 17813 | -0.318 | -0.0732 | Yes |
| 183 | Cdc6 | 17921 | -0.325 | -0.0675 | Yes |
| 184 | Meis2 | 18081 | -0.336 | -0.0641 | Yes |
| 185 | Hmmr | 18237 | -0.348 | -0.0600 | Yes |
| 186 | Jpt1 | 18340 | -0.357 | -0.0530 | Yes |
| 187 | Slc7a5 | 18348 | -0.358 | -0.0411 | Yes |
| 188 | Racgap1 | 18746 | -0.398 | -0.0476 | Yes |
| 189 | Srsf1 | 19031 | -0.430 | -0.0472 | Yes |
| 190 | Snrpd1 | 19201 | -0.451 | -0.0404 | Yes |
| 191 | Cdkn1b | 19306 | -0.468 | -0.0296 | Yes |
| 192 | Atf5 | 19653 | -0.550 | -0.0283 | Yes |
| 193 | Bcl3 | 19787 | -0.600 | -0.0145 | Yes |
| 194 | Hspa8 | 19967 | -0.777 | 0.0030 | Yes |

