| Dataset | GMP.GMP.neu_Pheno.cls #Group1_versus_Group2.GMP.neu_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | GMP.neu_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.23289503 |
| Normalized Enrichment Score (NES) | -1.0451247 |
| Nominal p-value | 0.4035433 |
| FDR q-value | 0.6682593 |
| FWER p-Value | 0.986 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cenpm | 506 | 0.651 | -0.0061 | No |
| 2 | Pttg1 | 1170 | 0.508 | -0.0244 | No |
| 3 | Rpa3 | 1324 | 0.489 | -0.0176 | No |
| 4 | Donson | 1804 | 0.430 | -0.0289 | No |
| 5 | Rnaseh2a | 1862 | 0.424 | -0.0192 | No |
| 6 | Brms1l | 2181 | 0.397 | -0.0234 | No |
| 7 | Spc24 | 3041 | 0.331 | -0.0568 | No |
| 8 | Rfc2 | 3350 | 0.310 | -0.0631 | No |
| 9 | Mxd3 | 3351 | 0.310 | -0.0539 | No |
| 10 | Gins4 | 4062 | 0.264 | -0.0818 | No |
| 11 | Dclre1b | 4106 | 0.262 | -0.0762 | No |
| 12 | Kif18b | 4197 | 0.256 | -0.0731 | No |
| 13 | Wdr90 | 4232 | 0.254 | -0.0673 | No |
| 14 | Shmt1 | 4524 | 0.239 | -0.0748 | No |
| 15 | Asf1b | 4542 | 0.238 | -0.0686 | No |
| 16 | Ube2t | 4645 | 0.233 | -0.0668 | No |
| 17 | Cdkn3 | 5083 | 0.213 | -0.0825 | No |
| 18 | Prdx4 | 5201 | 0.207 | -0.0822 | No |
| 19 | Pole | 5254 | 0.204 | -0.0788 | No |
| 20 | Pold1 | 5281 | 0.203 | -0.0740 | No |
| 21 | Asf1a | 5351 | 0.200 | -0.0716 | No |
| 22 | Timeless | 5436 | 0.195 | -0.0700 | No |
| 23 | Ppm1d | 5438 | 0.195 | -0.0642 | No |
| 24 | Dscc1 | 5446 | 0.194 | -0.0588 | No |
| 25 | Pms2 | 5477 | 0.192 | -0.0546 | No |
| 26 | Rbbp7 | 5535 | 0.190 | -0.0518 | No |
| 27 | Kif2c | 5648 | 0.183 | -0.0520 | No |
| 28 | Pds5b | 5718 | 0.180 | -0.0501 | No |
| 29 | Trp53 | 5795 | 0.176 | -0.0487 | No |
| 30 | Pold2 | 5807 | 0.175 | -0.0440 | No |
| 31 | Tubg1 | 5823 | 0.174 | -0.0396 | No |
| 32 | Mms22l | 5910 | 0.171 | -0.0388 | No |
| 33 | Pan2 | 6106 | 0.161 | -0.0439 | No |
| 34 | Cdc20 | 6138 | 0.160 | -0.0406 | No |
| 35 | Exosc8 | 6144 | 0.160 | -0.0361 | No |
| 36 | Ezh2 | 6481 | 0.146 | -0.0487 | No |
| 37 | Cnot9 | 6552 | 0.144 | -0.0480 | No |
| 38 | Trip13 | 6628 | 0.141 | -0.0476 | No |
| 39 | Aurkb | 6694 | 0.138 | -0.0467 | No |
| 40 | Tra2b | 6987 | 0.126 | -0.0577 | No |
| 41 | Rad1 | 7054 | 0.122 | -0.0574 | No |
| 42 | Rpa1 | 7189 | 0.117 | -0.0607 | No |
| 43 | Wee1 | 7204 | 0.116 | -0.0579 | No |
| 44 | Pola2 | 7282 | 0.113 | -0.0585 | No |
| 45 | Kif22 | 7298 | 0.113 | -0.0559 | No |
| 46 | Hnrnpd | 7325 | 0.111 | -0.0539 | No |
| 47 | Spag5 | 7395 | 0.107 | -0.0541 | No |
| 48 | Rfc3 | 7652 | 0.097 | -0.0642 | No |
| 49 | Cdk1 | 7655 | 0.097 | -0.0614 | No |
| 50 | Prkdc | 7691 | 0.096 | -0.0603 | No |
| 51 | Diaph3 | 7727 | 0.094 | -0.0592 | No |
| 52 | Depdc1a | 7757 | 0.093 | -0.0579 | No |
| 53 | Orc2 | 7814 | 0.091 | -0.0580 | No |
| 54 | Dctpp1 | 7858 | 0.089 | -0.0576 | No |
| 55 | Mlh1 | 7952 | 0.085 | -0.0597 | No |
| 56 | Stmn1 | 8026 | 0.082 | -0.0610 | No |
| 57 | Prim2 | 8036 | 0.082 | -0.0590 | No |
| 58 | Brca2 | 8113 | 0.079 | -0.0605 | No |
| 59 | Luc7l3 | 8228 | 0.074 | -0.0640 | No |
| 60 | Ilf3 | 8687 | 0.058 | -0.0854 | No |
| 61 | Plk1 | 8705 | 0.057 | -0.0846 | No |
| 62 | Suv39h1 | 8713 | 0.057 | -0.0832 | No |
| 63 | Ubr7 | 8757 | 0.055 | -0.0838 | No |
| 64 | Msh2 | 9077 | 0.043 | -0.0986 | No |
| 65 | Tipin | 9126 | 0.040 | -0.0998 | No |
| 66 | Psmc3ip | 9150 | 0.039 | -0.0998 | No |
| 67 | Ube2s | 9234 | 0.036 | -0.1029 | No |
| 68 | Ing3 | 9235 | 0.036 | -0.1018 | No |
| 69 | Rpa2 | 9484 | 0.026 | -0.1135 | No |
| 70 | Nop56 | 9541 | 0.025 | -0.1156 | No |
| 71 | Espl1 | 9556 | 0.024 | -0.1156 | No |
| 72 | Rad21 | 9576 | 0.023 | -0.1159 | No |
| 73 | Cse1l | 9617 | 0.022 | -0.1173 | No |
| 74 | Srsf2 | 9802 | 0.015 | -0.1261 | No |
| 75 | Rad50 | 9916 | 0.011 | -0.1315 | No |
| 76 | Tcf19 | 9930 | 0.010 | -0.1318 | No |
| 77 | Dut | 9935 | 0.010 | -0.1317 | No |
| 78 | Atad2 | 10008 | 0.008 | -0.1351 | No |
| 79 | Hmgb3 | 10077 | 0.006 | -0.1384 | No |
| 80 | Lig1 | 10218 | 0.001 | -0.1454 | No |
| 81 | Chek1 | 10224 | 0.001 | -0.1456 | No |
| 82 | Orc6 | 10233 | 0.001 | -0.1460 | No |
| 83 | Smc6 | 10325 | -0.002 | -0.1505 | No |
| 84 | Ctcf | 10372 | -0.003 | -0.1528 | No |
| 85 | Chek2 | 10540 | -0.008 | -0.1610 | No |
| 86 | Mcm7 | 10695 | -0.014 | -0.1683 | No |
| 87 | Nup107 | 10728 | -0.015 | -0.1695 | No |
| 88 | Stag1 | 10997 | -0.024 | -0.1823 | No |
| 89 | E2f8 | 11118 | -0.028 | -0.1875 | No |
| 90 | Pold3 | 11244 | -0.033 | -0.1928 | No |
| 91 | Pnn | 11293 | -0.035 | -0.1942 | No |
| 92 | Tk1 | 11311 | -0.036 | -0.1939 | No |
| 93 | Mcm6 | 11366 | -0.038 | -0.1955 | No |
| 94 | Dlgap5 | 11473 | -0.041 | -0.1996 | No |
| 95 | Pole4 | 11510 | -0.042 | -0.2002 | No |
| 96 | H2ax | 11548 | -0.043 | -0.2008 | No |
| 97 | Melk | 11572 | -0.044 | -0.2006 | No |
| 98 | Tubb5 | 11748 | -0.051 | -0.2079 | No |
| 99 | Psip1 | 11770 | -0.052 | -0.2074 | No |
| 100 | Birc5 | 11911 | -0.057 | -0.2128 | No |
| 101 | Prps1 | 11957 | -0.058 | -0.2133 | No |
| 102 | Nap1l1 | 12065 | -0.062 | -0.2169 | No |
| 103 | Mcm5 | 12068 | -0.062 | -0.2152 | No |
| 104 | Lmnb1 | 12070 | -0.062 | -0.2134 | No |
| 105 | Cdca8 | 12078 | -0.062 | -0.2119 | No |
| 106 | Ipo7 | 12112 | -0.063 | -0.2116 | No |
| 107 | Snrpb | 12159 | -0.065 | -0.2120 | No |
| 108 | Bard1 | 12174 | -0.066 | -0.2108 | No |
| 109 | Syncrip | 12255 | -0.069 | -0.2128 | No |
| 110 | Eed | 12272 | -0.069 | -0.2115 | No |
| 111 | Anp32e | 12287 | -0.070 | -0.2101 | No |
| 112 | Top2a | 12399 | -0.074 | -0.2135 | No |
| 113 | Hus1 | 12410 | -0.075 | -0.2118 | No |
| 114 | Nup153 | 12642 | -0.083 | -0.2210 | No |
| 115 | Nbn | 12748 | -0.087 | -0.2237 | No |
| 116 | Smc4 | 12770 | -0.088 | -0.2221 | No |
| 117 | Tmpo | 12814 | -0.090 | -0.2216 | No |
| 118 | Mcm4 | 12905 | -0.092 | -0.2234 | No |
| 119 | Brca1 | 12955 | -0.094 | -0.2231 | No |
| 120 | Pa2g4 | 12956 | -0.094 | -0.2203 | No |
| 121 | Smc3 | 13079 | -0.099 | -0.2234 | No |
| 122 | Mad2l1 | 13108 | -0.100 | -0.2219 | No |
| 123 | Cdc25b | 13252 | -0.105 | -0.2259 | No |
| 124 | Cdc25a | 13341 | -0.108 | -0.2272 | No |
| 125 | Rfc1 | 13377 | -0.110 | -0.2256 | No |
| 126 | Dek | 13511 | -0.114 | -0.2290 | No |
| 127 | Nasp | 13590 | -0.117 | -0.2294 | Yes |
| 128 | Smc1a | 13612 | -0.118 | -0.2270 | Yes |
| 129 | Mcm3 | 13727 | -0.122 | -0.2291 | Yes |
| 130 | Cdk4 | 13759 | -0.123 | -0.2270 | Yes |
| 131 | Mthfd2 | 13778 | -0.124 | -0.2242 | Yes |
| 132 | Tacc3 | 13857 | -0.127 | -0.2244 | Yes |
| 133 | Xpo1 | 13987 | -0.132 | -0.2270 | Yes |
| 134 | Mybl2 | 14046 | -0.134 | -0.2259 | Yes |
| 135 | Ccnb2 | 14071 | -0.135 | -0.2231 | Yes |
| 136 | Nudt21 | 14150 | -0.138 | -0.2229 | Yes |
| 137 | Bub1b | 14249 | -0.142 | -0.2236 | Yes |
| 138 | Tbrg4 | 14277 | -0.143 | -0.2207 | Yes |
| 139 | Hells | 14298 | -0.144 | -0.2174 | Yes |
| 140 | Eif2s1 | 14324 | -0.145 | -0.2143 | Yes |
| 141 | Gspt1 | 14517 | -0.153 | -0.2195 | Yes |
| 142 | Rad51ap1 | 14681 | -0.160 | -0.2229 | Yes |
| 143 | Xrcc6 | 14846 | -0.167 | -0.2262 | Yes |
| 144 | Usp1 | 14919 | -0.170 | -0.2248 | Yes |
| 145 | Cbx5 | 14948 | -0.171 | -0.2211 | Yes |
| 146 | H2az1 | 14988 | -0.173 | -0.2179 | Yes |
| 147 | Hmga1b | 15041 | -0.175 | -0.2153 | Yes |
| 148 | Myc | 15084 | -0.176 | -0.2122 | Yes |
| 149 | Gins1 | 15140 | -0.179 | -0.2096 | Yes |
| 150 | Paics | 15209 | -0.181 | -0.2077 | Yes |
| 151 | Cks2 | 15241 | -0.183 | -0.2038 | Yes |
| 152 | Ranbp1 | 15283 | -0.185 | -0.2003 | Yes |
| 153 | Ncapd2 | 15301 | -0.186 | -0.1957 | Yes |
| 154 | Mki67 | 15349 | -0.188 | -0.1924 | Yes |
| 155 | Cdkn1a | 15413 | -0.189 | -0.1899 | Yes |
| 156 | Pop7 | 15538 | -0.194 | -0.1904 | Yes |
| 157 | Phf5a | 15551 | -0.195 | -0.1852 | Yes |
| 158 | Lbr | 15568 | -0.195 | -0.1802 | Yes |
| 159 | Nup205 | 15729 | -0.202 | -0.1823 | Yes |
| 160 | Cit | 15975 | -0.213 | -0.1883 | Yes |
| 161 | Slbp | 16020 | -0.216 | -0.1841 | Yes |
| 162 | Mre11a | 16043 | -0.217 | -0.1787 | Yes |
| 163 | Plk4 | 16128 | -0.221 | -0.1763 | Yes |
| 164 | Kif4 | 16402 | -0.236 | -0.1831 | Yes |
| 165 | Cenpe | 16469 | -0.239 | -0.1793 | Yes |
| 166 | Mcm2 | 16576 | -0.243 | -0.1774 | Yes |
| 167 | Ssrp1 | 16671 | -0.248 | -0.1748 | Yes |
| 168 | Aurka | 16713 | -0.251 | -0.1694 | Yes |
| 169 | Cdkn2c | 16883 | -0.260 | -0.1701 | Yes |
| 170 | Nme1 | 16893 | -0.261 | -0.1628 | Yes |
| 171 | Nolc1 | 16920 | -0.262 | -0.1563 | Yes |
| 172 | Spc25 | 17215 | -0.278 | -0.1629 | Yes |
| 173 | Cks1b | 17253 | -0.281 | -0.1564 | Yes |
| 174 | Ddx39a | 17662 | -0.308 | -0.1678 | Yes |
| 175 | Pcna | 17745 | -0.313 | -0.1626 | Yes |
| 176 | Rad51c | 17793 | -0.316 | -0.1555 | Yes |
| 177 | Ung | 17941 | -0.327 | -0.1532 | Yes |
| 178 | Tfrc | 18104 | -0.338 | -0.1513 | Yes |
| 179 | Dck | 18157 | -0.342 | -0.1437 | Yes |
| 180 | Hmmr | 18237 | -0.348 | -0.1374 | Yes |
| 181 | Hmgb2 | 18243 | -0.349 | -0.1272 | Yes |
| 182 | Jpt1 | 18340 | -0.357 | -0.1214 | Yes |
| 183 | Ccne1 | 18465 | -0.371 | -0.1166 | Yes |
| 184 | Dnmt1 | 18556 | -0.378 | -0.1099 | Yes |
| 185 | Ppp1r8 | 18726 | -0.397 | -0.1066 | Yes |
| 186 | Racgap1 | 18746 | -0.398 | -0.0957 | Yes |
| 187 | Ak2 | 18826 | -0.407 | -0.0876 | Yes |
| 188 | Srsf1 | 19031 | -0.430 | -0.0851 | Yes |
| 189 | Gins3 | 19095 | -0.437 | -0.0752 | Yes |
| 190 | Ran | 19224 | -0.454 | -0.0682 | Yes |
| 191 | Lyar | 19275 | -0.464 | -0.0569 | Yes |
| 192 | Lsm8 | 19289 | -0.466 | -0.0436 | Yes |
| 193 | Rrm2 | 19292 | -0.466 | -0.0299 | Yes |
| 194 | Cdkn1b | 19306 | -0.468 | -0.0166 | Yes |
| 195 | Zw10 | 19359 | -0.477 | -0.0050 | Yes |
| 196 | Cdca3 | 19855 | -0.641 | -0.0109 | Yes |
| 197 | Ccp110 | 19874 | -0.653 | 0.0077 | Yes |

