| Dataset | GMP.GMP.mono_Pheno.cls #Group6_versus_Group8.GMP.mono_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | GMP.mono_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_HEME_METABOLISM |
| Enrichment Score (ES) | -0.21929339 |
| Normalized Enrichment Score (NES) | -1.1547458 |
| Nominal p-value | 0.21370968 |
| FDR q-value | 0.6835341 |
| FWER p-Value | 0.956 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Slc30a10 | 40 | 1.242 | 0.0323 | No |
| 2 | Pcx | 267 | 0.825 | 0.0453 | No |
| 3 | Cdr2 | 989 | 0.570 | 0.0302 | No |
| 4 | Ackr1 | 1077 | 0.557 | 0.0418 | No |
| 5 | Xk | 1617 | 0.485 | 0.0321 | No |
| 6 | Atg4a | 1626 | 0.483 | 0.0450 | No |
| 7 | Fn3k | 1851 | 0.444 | 0.0476 | No |
| 8 | C3 | 1890 | 0.439 | 0.0580 | No |
| 9 | Smox | 2284 | 0.403 | 0.0523 | No |
| 10 | Ppp2r5b | 2876 | 0.368 | 0.0372 | No |
| 11 | Sidt2 | 2891 | 0.366 | 0.0466 | No |
| 12 | Tent5c | 3098 | 0.353 | 0.0475 | No |
| 13 | Arhgef12 | 3184 | 0.344 | 0.0533 | No |
| 14 | Sec14l1 | 3198 | 0.343 | 0.0622 | No |
| 15 | Pdzk1ip1 | 3266 | 0.337 | 0.0686 | No |
| 16 | Daam1 | 3468 | 0.318 | 0.0687 | No |
| 17 | Slc25a38 | 3546 | 0.311 | 0.0739 | No |
| 18 | Map2k3 | 3605 | 0.307 | 0.0799 | No |
| 19 | Rap1gap | 3846 | 0.290 | 0.0776 | No |
| 20 | Asns | 3986 | 0.281 | 0.0794 | No |
| 21 | Synj1 | 4144 | 0.272 | 0.0801 | No |
| 22 | Ermap | 4353 | 0.261 | 0.0784 | No |
| 23 | Tfrc | 4634 | 0.249 | 0.0733 | No |
| 24 | Gde1 | 4849 | 0.240 | 0.0707 | No |
| 25 | Kdm7a | 5008 | 0.230 | 0.0703 | No |
| 26 | Slc22a4 | 5494 | 0.215 | 0.0555 | No |
| 27 | Hagh | 5725 | 0.203 | 0.0513 | No |
| 28 | Bmp2k | 5963 | 0.197 | 0.0466 | No |
| 29 | Slc6a9 | 6112 | 0.191 | 0.0455 | No |
| 30 | Trim10 | 6463 | 0.175 | 0.0354 | No |
| 31 | Lamp2 | 6486 | 0.175 | 0.0392 | No |
| 32 | Btg2 | 6512 | 0.174 | 0.0429 | No |
| 33 | Slc6a8 | 6615 | 0.169 | 0.0432 | No |
| 34 | Picalm | 6643 | 0.168 | 0.0467 | No |
| 35 | Mxi1 | 6681 | 0.167 | 0.0497 | No |
| 36 | Rhd | 6822 | 0.162 | 0.0481 | No |
| 37 | Dcaf10 | 7154 | 0.148 | 0.0381 | No |
| 38 | Igsf3 | 7159 | 0.148 | 0.0419 | No |
| 39 | Fech | 7195 | 0.147 | 0.0445 | No |
| 40 | Nnt | 7215 | 0.146 | 0.0477 | No |
| 41 | Fbxo34 | 7222 | 0.146 | 0.0514 | No |
| 42 | Osbp2 | 7224 | 0.146 | 0.0554 | No |
| 43 | Mpp1 | 7242 | 0.145 | 0.0586 | No |
| 44 | Tspan5 | 7287 | 0.143 | 0.0607 | No |
| 45 | Eif2ak1 | 7445 | 0.137 | 0.0577 | No |
| 46 | Acp5 | 7592 | 0.132 | 0.0551 | No |
| 47 | Slc2a1 | 7619 | 0.131 | 0.0576 | No |
| 48 | Dcun1d1 | 7825 | 0.124 | 0.0523 | No |
| 49 | Slc30a1 | 8005 | 0.118 | 0.0479 | No |
| 50 | Hebp1 | 8094 | 0.115 | 0.0473 | No |
| 51 | Ppox | 8121 | 0.114 | 0.0493 | No |
| 52 | Agpat4 | 8172 | 0.113 | 0.0502 | No |
| 53 | Nek7 | 8364 | 0.107 | 0.0450 | No |
| 54 | Gclc | 8701 | 0.096 | 0.0333 | No |
| 55 | Aldh6a1 | 8755 | 0.094 | 0.0337 | No |
| 56 | Rnf123 | 8814 | 0.093 | 0.0337 | No |
| 57 | Htra2 | 8848 | 0.092 | 0.0348 | No |
| 58 | Kel | 9075 | 0.085 | 0.0275 | No |
| 59 | Usp15 | 9078 | 0.085 | 0.0298 | No |
| 60 | Mocos | 9162 | 0.083 | 0.0285 | No |
| 61 | Nr3c1 | 9293 | 0.080 | 0.0252 | No |
| 62 | Sptb | 9410 | 0.076 | 0.0223 | No |
| 63 | Cdc27 | 9571 | 0.071 | 0.0174 | No |
| 64 | Abcb6 | 9719 | 0.067 | 0.0130 | No |
| 65 | Gmps | 9911 | 0.061 | 0.0065 | No |
| 66 | Ypel5 | 10042 | 0.057 | 0.0025 | No |
| 67 | Gapvd1 | 10440 | 0.046 | -0.0131 | No |
| 68 | Epb41 | 10465 | 0.045 | -0.0129 | No |
| 69 | Nfe2l1 | 10527 | 0.044 | -0.0143 | No |
| 70 | Rcl1 | 10669 | 0.040 | -0.0193 | No |
| 71 | Tnrc6b | 10856 | 0.034 | -0.0263 | No |
| 72 | Epor | 10866 | 0.034 | -0.0257 | No |
| 73 | Alas2 | 10932 | 0.032 | -0.0276 | No |
| 74 | Ank1 | 10951 | 0.031 | -0.0275 | No |
| 75 | Mospd1 | 11008 | 0.030 | -0.0291 | No |
| 76 | Foxo3 | 11241 | 0.023 | -0.0384 | No |
| 77 | Clcn3 | 11444 | 0.017 | -0.0465 | No |
| 78 | P4ha2 | 11515 | 0.014 | -0.0491 | No |
| 79 | Fbxo7 | 11616 | 0.012 | -0.0531 | No |
| 80 | Cir1 | 11706 | 0.009 | -0.0566 | No |
| 81 | Mark3 | 11857 | 0.005 | -0.0629 | No |
| 82 | Htatip2 | 11905 | 0.003 | -0.0648 | No |
| 83 | Riok3 | 11960 | 0.002 | -0.0670 | No |
| 84 | Gclm | 12604 | -0.007 | -0.0943 | No |
| 85 | Khnyn | 12775 | -0.012 | -0.1012 | No |
| 86 | Selenbp1 | 12801 | -0.013 | -0.1019 | No |
| 87 | Mfhas1 | 12920 | -0.016 | -0.1065 | No |
| 88 | Alad | 13066 | -0.020 | -0.1122 | No |
| 89 | Spta1 | 13097 | -0.021 | -0.1129 | No |
| 90 | Rbm5 | 13190 | -0.023 | -0.1162 | No |
| 91 | Sdcbp | 13234 | -0.025 | -0.1173 | No |
| 92 | Rbm38 | 13311 | -0.027 | -0.1198 | No |
| 93 | Narf | 13446 | -0.030 | -0.1247 | No |
| 94 | Ucp2 | 13473 | -0.031 | -0.1250 | No |
| 95 | Slc11a2 | 13580 | -0.034 | -0.1286 | No |
| 96 | E2f2 | 13682 | -0.037 | -0.1319 | No |
| 97 | Marchf8 | 13722 | -0.038 | -0.1325 | No |
| 98 | Adipor1 | 13814 | -0.041 | -0.1352 | No |
| 99 | Ranbp10 | 13868 | -0.043 | -0.1363 | No |
| 100 | Lrp10 | 13995 | -0.047 | -0.1404 | No |
| 101 | Gypc | 14039 | -0.048 | -0.1409 | No |
| 102 | Cast | 14065 | -0.049 | -0.1407 | No |
| 103 | Endod1 | 14154 | -0.051 | -0.1430 | No |
| 104 | Hmbs | 14191 | -0.052 | -0.1431 | No |
| 105 | Add1 | 14299 | -0.055 | -0.1462 | No |
| 106 | Kat2b | 14350 | -0.056 | -0.1468 | No |
| 107 | Glrx5 | 14447 | -0.059 | -0.1493 | No |
| 108 | Rnf19a | 14448 | -0.059 | -0.1476 | No |
| 109 | Btrc | 14456 | -0.059 | -0.1463 | No |
| 110 | Mgst3 | 14510 | -0.061 | -0.1469 | No |
| 111 | Tfdp2 | 14630 | -0.064 | -0.1502 | No |
| 112 | Snca | 14633 | -0.064 | -0.1486 | No |
| 113 | Pgls | 14711 | -0.066 | -0.1500 | No |
| 114 | Xpo7 | 14741 | -0.067 | -0.1494 | No |
| 115 | Rad23a | 14760 | -0.068 | -0.1483 | No |
| 116 | Trak2 | 15010 | -0.076 | -0.1569 | No |
| 117 | Optn | 15013 | -0.076 | -0.1549 | No |
| 118 | Aqp3 | 15478 | -0.091 | -0.1722 | No |
| 119 | Acsl6 | 15750 | -0.099 | -0.1810 | No |
| 120 | Rhag | 15820 | -0.101 | -0.1812 | No |
| 121 | Ncoa4 | 15875 | -0.103 | -0.1807 | No |
| 122 | Slc7a11 | 16256 | -0.115 | -0.1937 | No |
| 123 | Tmem9b | 16287 | -0.117 | -0.1918 | No |
| 124 | Ctsb | 16290 | -0.117 | -0.1887 | No |
| 125 | Blvra | 16302 | -0.117 | -0.1860 | No |
| 126 | Top1 | 16420 | -0.121 | -0.1876 | No |
| 127 | Tcea1 | 16516 | -0.124 | -0.1883 | No |
| 128 | Nfe2 | 16744 | -0.133 | -0.1943 | No |
| 129 | Psmd9 | 16918 | -0.139 | -0.1979 | No |
| 130 | Lpin2 | 17028 | -0.143 | -0.1986 | No |
| 131 | Atp6v0a1 | 17029 | -0.143 | -0.1947 | No |
| 132 | Slc4a1 | 17114 | -0.146 | -0.1943 | No |
| 133 | Ubac1 | 17116 | -0.146 | -0.1903 | No |
| 134 | Minpp1 | 17141 | -0.147 | -0.1873 | No |
| 135 | Ezh1 | 17275 | -0.152 | -0.1888 | No |
| 136 | H1f0 | 17482 | -0.159 | -0.1933 | No |
| 137 | Tal1 | 17642 | -0.165 | -0.1955 | No |
| 138 | Bach1 | 17781 | -0.170 | -0.1967 | No |
| 139 | Klf1 | 17803 | -0.171 | -0.1929 | No |
| 140 | Abcg2 | 17881 | -0.175 | -0.1914 | No |
| 141 | Tmcc2 | 18007 | -0.179 | -0.1918 | No |
| 142 | Car1 | 18281 | -0.188 | -0.1983 | No |
| 143 | Slc66a2 | 18533 | -0.199 | -0.2036 | No |
| 144 | Dcaf11 | 18540 | -0.199 | -0.1984 | No |
| 145 | Marchf2 | 18947 | -0.216 | -0.2097 | No |
| 146 | Arl2bp | 18948 | -0.216 | -0.2038 | No |
| 147 | Pigq | 19031 | -0.220 | -0.2013 | No |
| 148 | Bnip3l | 19454 | -0.238 | -0.2128 | Yes |
| 149 | Klf3 | 19497 | -0.241 | -0.2080 | Yes |
| 150 | Nudt4 | 19602 | -0.245 | -0.2057 | Yes |
| 151 | Ctns | 19700 | -0.251 | -0.2029 | Yes |
| 152 | Cpox | 19706 | -0.251 | -0.1963 | Yes |
| 153 | Urod | 20115 | -0.274 | -0.2061 | Yes |
| 154 | Mkrn1 | 20127 | -0.275 | -0.1991 | Yes |
| 155 | Car2 | 20228 | -0.281 | -0.1956 | Yes |
| 156 | Vezf1 | 20338 | -0.287 | -0.1924 | Yes |
| 157 | Dmtn | 20427 | -0.290 | -0.1882 | Yes |
| 158 | Bpgm | 20503 | -0.294 | -0.1834 | Yes |
| 159 | Cat | 20608 | -0.301 | -0.1796 | Yes |
| 160 | Trim58 | 20754 | -0.309 | -0.1773 | Yes |
| 161 | Tyr | 20949 | -0.319 | -0.1768 | Yes |
| 162 | Mboat2 | 21052 | -0.326 | -0.1722 | Yes |
| 163 | Hdgf | 21171 | -0.333 | -0.1681 | Yes |
| 164 | Ccnd3 | 21324 | -0.343 | -0.1652 | Yes |
| 165 | Tns1 | 21525 | -0.355 | -0.1640 | Yes |
| 166 | Fbxo9 | 21535 | -0.356 | -0.1546 | Yes |
| 167 | Ccdc28a | 21683 | -0.368 | -0.1508 | Yes |
| 168 | Foxj2 | 21778 | -0.376 | -0.1444 | Yes |
| 169 | Lmo2 | 21882 | -0.387 | -0.1382 | Yes |
| 170 | Tspo2 | 22252 | -0.425 | -0.1423 | Yes |
| 171 | Icam4 | 22341 | -0.434 | -0.1342 | Yes |
| 172 | Prdx2 | 22370 | -0.437 | -0.1234 | Yes |
| 173 | Bsg | 22428 | -0.444 | -0.1137 | Yes |
| 174 | Ctse | 22435 | -0.445 | -0.1017 | Yes |
| 175 | Add2 | 22488 | -0.453 | -0.0915 | Yes |
| 176 | Epb42 | 22677 | -0.479 | -0.0864 | Yes |
| 177 | Uros | 23039 | -0.543 | -0.0869 | Yes |
| 178 | Blvrb | 23064 | -0.547 | -0.0729 | Yes |
| 179 | Ell2 | 23165 | -0.574 | -0.0615 | Yes |
| 180 | Myl4 | 23361 | -0.643 | -0.0522 | Yes |
| 181 | Slc10a3 | 23367 | -0.645 | -0.0347 | Yes |
| 182 | Gata1 | 23443 | -0.694 | -0.0189 | Yes |
| 183 | Aldh1l1 | 23602 | -0.969 | 0.0009 | Yes |

