| Dataset | GMP.GMP.mono_Pheno.cls #Group6_versus_Group8.GMP.mono_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | GMP.mono_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_ESTROGEN_RESPONSE_EARLY |
| Enrichment Score (ES) | -0.24326073 |
| Normalized Enrichment Score (NES) | -1.0499704 |
| Nominal p-value | 0.3554217 |
| FDR q-value | 0.6735281 |
| FWER p-Value | 0.995 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Klf4 | 187 | 0.909 | 0.0159 | No |
| 2 | Pdzk1 | 246 | 0.842 | 0.0356 | No |
| 3 | Adcy1 | 523 | 0.704 | 0.0423 | No |
| 4 | Papss2 | 665 | 0.656 | 0.0536 | No |
| 5 | Thsd4 | 724 | 0.628 | 0.0676 | No |
| 6 | Slc7a2 | 828 | 0.597 | 0.0789 | No |
| 7 | Lrig1 | 866 | 0.587 | 0.0928 | No |
| 8 | Fcmr | 1184 | 0.548 | 0.0937 | No |
| 9 | Fos | 1566 | 0.496 | 0.0905 | No |
| 10 | Gla | 1730 | 0.463 | 0.0957 | No |
| 11 | Sh3bp5 | 1835 | 0.446 | 0.1030 | No |
| 12 | Add3 | 1860 | 0.443 | 0.1136 | No |
| 13 | Zfp185 | 2257 | 0.405 | 0.1074 | No |
| 14 | Ovol2 | 2390 | 0.399 | 0.1122 | No |
| 15 | Tmprss3 | 2591 | 0.384 | 0.1138 | No |
| 16 | Podxl | 2857 | 0.370 | 0.1122 | No |
| 17 | Olfml3 | 3001 | 0.361 | 0.1156 | No |
| 18 | Stc2 | 3117 | 0.351 | 0.1199 | No |
| 19 | Cxcl12 | 3143 | 0.348 | 0.1280 | No |
| 20 | Rhod | 3236 | 0.340 | 0.1330 | No |
| 21 | Ncor2 | 3250 | 0.339 | 0.1414 | No |
| 22 | Tgm2 | 3309 | 0.333 | 0.1476 | No |
| 23 | Frk | 3497 | 0.315 | 0.1479 | No |
| 24 | Abca3 | 3584 | 0.308 | 0.1524 | No |
| 25 | Tiam1 | 3591 | 0.308 | 0.1602 | No |
| 26 | Dhrs3 | 3932 | 0.284 | 0.1532 | No |
| 27 | Unc119 | 4085 | 0.275 | 0.1539 | No |
| 28 | Tmem164 | 4172 | 0.271 | 0.1574 | No |
| 29 | Svil | 4197 | 0.269 | 0.1634 | No |
| 30 | Ret | 4747 | 0.246 | 0.1465 | No |
| 31 | Rps6ka2 | 4852 | 0.239 | 0.1483 | No |
| 32 | Aldh3b1 | 4919 | 0.235 | 0.1517 | No |
| 33 | Gfra1 | 5698 | 0.205 | 0.1239 | No |
| 34 | Hes1 | 5816 | 0.199 | 0.1242 | No |
| 35 | Ttc39a | 6746 | 0.165 | 0.0889 | No |
| 36 | Krt8 | 6969 | 0.155 | 0.0835 | No |
| 37 | Dhcr7 | 7135 | 0.149 | 0.0804 | No |
| 38 | Cd44 | 7139 | 0.149 | 0.0842 | No |
| 39 | Fdft1 | 7324 | 0.142 | 0.0800 | No |
| 40 | Slc2a1 | 7619 | 0.131 | 0.0709 | No |
| 41 | Gab2 | 7651 | 0.130 | 0.0730 | No |
| 42 | Dlc1 | 7717 | 0.127 | 0.0736 | No |
| 43 | Tjp3 | 7724 | 0.127 | 0.0767 | No |
| 44 | Slc22a5 | 7832 | 0.124 | 0.0754 | No |
| 45 | B4galt1 | 7927 | 0.121 | 0.0746 | No |
| 46 | Mreg | 7958 | 0.120 | 0.0764 | No |
| 47 | Scarb1 | 8127 | 0.114 | 0.0723 | No |
| 48 | Aff1 | 8160 | 0.113 | 0.0739 | No |
| 49 | Calcr | 8199 | 0.112 | 0.0752 | No |
| 50 | Mindy1 | 8200 | 0.112 | 0.0781 | No |
| 51 | Igf1r | 8217 | 0.112 | 0.0804 | No |
| 52 | Sema3b | 8279 | 0.110 | 0.0807 | No |
| 53 | Fkbp5 | 8379 | 0.107 | 0.0793 | No |
| 54 | Jak2 | 8385 | 0.107 | 0.0819 | No |
| 55 | Itpk1 | 8391 | 0.106 | 0.0844 | No |
| 56 | Rab31 | 8454 | 0.104 | 0.0845 | No |
| 57 | Fkbp4 | 8771 | 0.094 | 0.0735 | No |
| 58 | Cbfa2t3 | 8854 | 0.092 | 0.0724 | No |
| 59 | Nadsyn1 | 8899 | 0.090 | 0.0729 | No |
| 60 | Akap1 | 9058 | 0.086 | 0.0685 | No |
| 61 | Ugcg | 9098 | 0.085 | 0.0690 | No |
| 62 | Sfn | 9113 | 0.084 | 0.0707 | No |
| 63 | Nav2 | 9302 | 0.079 | 0.0647 | No |
| 64 | Il6st | 9350 | 0.078 | 0.0648 | No |
| 65 | Tob1 | 9353 | 0.078 | 0.0667 | No |
| 66 | Siah2 | 9454 | 0.074 | 0.0644 | No |
| 67 | Ptges | 9517 | 0.072 | 0.0637 | No |
| 68 | Opn3 | 9641 | 0.069 | 0.0602 | No |
| 69 | Amfr | 9667 | 0.068 | 0.0609 | No |
| 70 | Deptor | 9760 | 0.066 | 0.0587 | No |
| 71 | Syngr1 | 9888 | 0.062 | 0.0550 | No |
| 72 | Slc26a2 | 10133 | 0.055 | 0.0460 | No |
| 73 | Rrp12 | 10180 | 0.053 | 0.0454 | No |
| 74 | Xbp1 | 10182 | 0.053 | 0.0468 | No |
| 75 | Tiparp | 10251 | 0.051 | 0.0452 | No |
| 76 | Med13l | 10425 | 0.046 | 0.0391 | No |
| 77 | Slc16a1 | 10573 | 0.042 | 0.0339 | No |
| 78 | Rara | 10588 | 0.042 | 0.0344 | No |
| 79 | Elovl5 | 10600 | 0.041 | 0.0350 | No |
| 80 | Muc1 | 10610 | 0.041 | 0.0357 | No |
| 81 | Slc24a3 | 10637 | 0.040 | 0.0357 | No |
| 82 | Med24 | 10680 | 0.039 | 0.0349 | No |
| 83 | Rbbp8 | 10947 | 0.032 | 0.0244 | No |
| 84 | Isg20l2 | 11006 | 0.030 | 0.0227 | No |
| 85 | Calb2 | 11145 | 0.026 | 0.0175 | No |
| 86 | Sec14l2 | 11384 | 0.019 | 0.0079 | No |
| 87 | Abhd2 | 11396 | 0.018 | 0.0079 | No |
| 88 | Mapt | 11450 | 0.017 | 0.0061 | No |
| 89 | Slc1a4 | 11561 | 0.013 | 0.0017 | No |
| 90 | Celsr1 | 11702 | 0.009 | -0.0040 | No |
| 91 | Inpp5f | 11880 | 0.004 | -0.0114 | No |
| 92 | Bcl2 | 12405 | -0.003 | -0.0337 | No |
| 93 | Adcy9 | 12477 | -0.004 | -0.0366 | No |
| 94 | Krt18 | 12647 | -0.008 | -0.0436 | No |
| 95 | Kcnk5 | 12650 | -0.008 | -0.0435 | No |
| 96 | Fhl2 | 12804 | -0.013 | -0.0497 | No |
| 97 | Pgr | 13019 | -0.018 | -0.0583 | No |
| 98 | Nrip1 | 13032 | -0.019 | -0.0583 | No |
| 99 | Snx24 | 13076 | -0.020 | -0.0597 | No |
| 100 | Esrp2 | 13081 | -0.020 | -0.0593 | No |
| 101 | Slc7a5 | 13090 | -0.020 | -0.0591 | No |
| 102 | Cant1 | 13310 | -0.027 | -0.0677 | No |
| 103 | Kdm4b | 13349 | -0.028 | -0.0686 | No |
| 104 | Fasn | 13694 | -0.038 | -0.0823 | No |
| 105 | Elf1 | 13871 | -0.043 | -0.0887 | No |
| 106 | Ccnd1 | 13886 | -0.043 | -0.0881 | No |
| 107 | Endod1 | 14154 | -0.051 | -0.0982 | No |
| 108 | Bhlhe40 | 14500 | -0.060 | -0.1113 | No |
| 109 | Wwc1 | 14701 | -0.066 | -0.1181 | No |
| 110 | Myb | 14746 | -0.067 | -0.1182 | No |
| 111 | Rhobtb3 | 15030 | -0.077 | -0.1283 | No |
| 112 | Slc39a6 | 15036 | -0.077 | -0.1265 | No |
| 113 | Slc1a1 | 15054 | -0.078 | -0.1251 | No |
| 114 | Abat | 15189 | -0.082 | -0.1287 | No |
| 115 | Il17rb | 15207 | -0.083 | -0.1273 | No |
| 116 | Slc19a2 | 15220 | -0.083 | -0.1256 | No |
| 117 | Wfs1 | 15229 | -0.083 | -0.1238 | No |
| 118 | Greb1 | 15249 | -0.084 | -0.1223 | No |
| 119 | Clic3 | 15297 | -0.086 | -0.1221 | No |
| 120 | Aqp3 | 15478 | -0.091 | -0.1274 | No |
| 121 | Pmaip1 | 15524 | -0.092 | -0.1268 | No |
| 122 | Slc37a1 | 15559 | -0.093 | -0.1258 | No |
| 123 | Flnb | 15889 | -0.103 | -0.1372 | No |
| 124 | Mlph | 15963 | -0.106 | -0.1375 | No |
| 125 | Mpped2 | 16034 | -0.108 | -0.1376 | No |
| 126 | Sybu | 16231 | -0.114 | -0.1430 | No |
| 127 | Slc27a2 | 16521 | -0.125 | -0.1520 | No |
| 128 | P2ry2 | 16629 | -0.129 | -0.1532 | No |
| 129 | Chpt1 | 16686 | -0.131 | -0.1521 | No |
| 130 | Kazn | 16864 | -0.137 | -0.1561 | No |
| 131 | Mybbp1a | 17008 | -0.142 | -0.1585 | No |
| 132 | Foxc1 | 17218 | -0.150 | -0.1634 | No |
| 133 | Anxa9 | 17612 | -0.164 | -0.1759 | No |
| 134 | Ar | 17676 | -0.167 | -0.1742 | No |
| 135 | Cish | 17906 | -0.176 | -0.1793 | No |
| 136 | Syt12 | 18203 | -0.185 | -0.1871 | No |
| 137 | Rab17 | 18497 | -0.198 | -0.1944 | No |
| 138 | Olfm1 | 18700 | -0.205 | -0.1976 | No |
| 139 | Tgif2 | 19064 | -0.221 | -0.2072 | No |
| 140 | Rasgrp1 | 19119 | -0.222 | -0.2037 | No |
| 141 | Rapgefl1 | 19601 | -0.245 | -0.2178 | No |
| 142 | Bag1 | 19765 | -0.255 | -0.2180 | No |
| 143 | Nxt1 | 19987 | -0.266 | -0.2204 | No |
| 144 | Retreg1 | 19995 | -0.267 | -0.2137 | No |
| 145 | Pdlim3 | 20124 | -0.275 | -0.2120 | No |
| 146 | Ppif | 20434 | -0.290 | -0.2175 | No |
| 147 | Scnn1a | 20559 | -0.298 | -0.2150 | No |
| 148 | Tbc1d30 | 20664 | -0.304 | -0.2114 | No |
| 149 | Bcl11b | 21412 | -0.351 | -0.2340 | Yes |
| 150 | Tubb2b | 21427 | -0.351 | -0.2254 | Yes |
| 151 | Cyp26b1 | 21430 | -0.351 | -0.2162 | Yes |
| 152 | Car12 | 21571 | -0.359 | -0.2128 | Yes |
| 153 | Klf10 | 21586 | -0.360 | -0.2039 | Yes |
| 154 | Tsku | 21587 | -0.361 | -0.1944 | Yes |
| 155 | Tpd52l1 | 21711 | -0.370 | -0.1899 | Yes |
| 156 | Mybl1 | 21816 | -0.380 | -0.1844 | Yes |
| 157 | Hr | 22067 | -0.403 | -0.1844 | Yes |
| 158 | Reep1 | 22118 | -0.410 | -0.1758 | Yes |
| 159 | Farp1 | 22195 | -0.419 | -0.1680 | Yes |
| 160 | Asb13 | 22272 | -0.426 | -0.1600 | Yes |
| 161 | Dynlt3 | 22474 | -0.451 | -0.1568 | Yes |
| 162 | Myc | 22533 | -0.459 | -0.1472 | Yes |
| 163 | Celsr2 | 22542 | -0.460 | -0.1354 | Yes |
| 164 | Igfbp4 | 22827 | -0.502 | -0.1343 | Yes |
| 165 | Blvrb | 23064 | -0.547 | -0.1300 | Yes |
| 166 | Elovl2 | 23102 | -0.557 | -0.1169 | Yes |
| 167 | Arl3 | 23202 | -0.589 | -0.1057 | Yes |
| 168 | Plaat3 | 23218 | -0.594 | -0.0907 | Yes |
| 169 | Mast4 | 23248 | -0.602 | -0.0761 | Yes |
| 170 | Gja1 | 23269 | -0.609 | -0.0609 | Yes |
| 171 | Sult2b1 | 23339 | -0.630 | -0.0473 | Yes |
| 172 | Pex11a | 23394 | -0.667 | -0.0321 | Yes |
| 173 | Myof | 23524 | -0.767 | -0.0174 | Yes |
| 174 | Ablim1 | 23550 | -0.822 | 0.0032 | Yes |

