| Dataset | GMP.GMP.mono_Pheno.cls #Group6_versus_Group8.GMP.mono_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | GMP.mono_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.21047135 |
| Normalized Enrichment Score (NES) | -0.9478698 |
| Nominal p-value | 0.49603173 |
| FDR q-value | 0.7950867 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cks2 | 1602 | 0.489 | -0.0513 | No |
| 2 | Cdkn2a | 1776 | 0.454 | -0.0429 | No |
| 3 | Ube2s | 1827 | 0.447 | -0.0294 | No |
| 4 | Pan2 | 2596 | 0.384 | -0.0488 | No |
| 5 | Pold1 | 3122 | 0.350 | -0.0590 | No |
| 6 | Mxd3 | 3606 | 0.306 | -0.0689 | No |
| 7 | Tubg1 | 3859 | 0.289 | -0.0696 | No |
| 8 | Cit | 3991 | 0.281 | -0.0653 | No |
| 9 | Mybl2 | 4001 | 0.281 | -0.0559 | No |
| 10 | Bard1 | 4062 | 0.277 | -0.0488 | No |
| 11 | Mre11a | 4461 | 0.259 | -0.0568 | No |
| 12 | Espl1 | 4583 | 0.251 | -0.0532 | No |
| 13 | Tfrc | 4634 | 0.249 | -0.0466 | No |
| 14 | Plk1 | 4724 | 0.247 | -0.0418 | No |
| 15 | Pole | 4891 | 0.237 | -0.0406 | No |
| 16 | Mki67 | 4983 | 0.232 | -0.0364 | No |
| 17 | Tk1 | 5051 | 0.227 | -0.0313 | No |
| 18 | Tbrg4 | 5161 | 0.225 | -0.0281 | No |
| 19 | Ccp110 | 6020 | 0.194 | -0.0580 | No |
| 20 | Tra2b | 6051 | 0.194 | -0.0525 | No |
| 21 | Slbp | 6098 | 0.192 | -0.0478 | No |
| 22 | Tcf19 | 6117 | 0.190 | -0.0419 | No |
| 23 | Kif22 | 6122 | 0.190 | -0.0354 | No |
| 24 | Racgap1 | 6440 | 0.176 | -0.0428 | No |
| 25 | Spag5 | 6730 | 0.165 | -0.0494 | No |
| 26 | Mms22l | 6843 | 0.161 | -0.0485 | No |
| 27 | Diaph3 | 6884 | 0.159 | -0.0447 | No |
| 28 | Ilf3 | 6909 | 0.159 | -0.0402 | No |
| 29 | Melk | 6912 | 0.158 | -0.0347 | No |
| 30 | Srsf2 | 7004 | 0.154 | -0.0332 | No |
| 31 | Dnmt1 | 7111 | 0.150 | -0.0325 | No |
| 32 | Anp32e | 7531 | 0.134 | -0.0457 | No |
| 33 | Ppm1d | 7588 | 0.132 | -0.0435 | No |
| 34 | Rrm2 | 7610 | 0.131 | -0.0398 | No |
| 35 | Xpo1 | 7648 | 0.130 | -0.0368 | No |
| 36 | Nup205 | 7684 | 0.129 | -0.0338 | No |
| 37 | Pola2 | 7703 | 0.128 | -0.0301 | No |
| 38 | Pcna | 8016 | 0.118 | -0.0394 | No |
| 39 | Dscc1 | 8123 | 0.114 | -0.0399 | No |
| 40 | Mcm5 | 8265 | 0.110 | -0.0421 | No |
| 41 | Asf1b | 8464 | 0.104 | -0.0469 | No |
| 42 | Dlgap5 | 8567 | 0.100 | -0.0477 | No |
| 43 | Depdc1a | 8611 | 0.099 | -0.0461 | No |
| 44 | Brca2 | 8689 | 0.096 | -0.0461 | No |
| 45 | Bub1b | 8694 | 0.096 | -0.0429 | No |
| 46 | Cenpm | 8699 | 0.096 | -0.0397 | No |
| 47 | Tacc3 | 8708 | 0.096 | -0.0367 | No |
| 48 | Lbr | 8807 | 0.093 | -0.0376 | No |
| 49 | Ube2t | 8917 | 0.090 | -0.0392 | No |
| 50 | Shmt1 | 9135 | 0.084 | -0.0455 | No |
| 51 | Prim2 | 9182 | 0.083 | -0.0446 | No |
| 52 | Stag1 | 9332 | 0.078 | -0.0482 | No |
| 53 | Mlh1 | 9492 | 0.073 | -0.0524 | No |
| 54 | Ipo7 | 9506 | 0.073 | -0.0505 | No |
| 55 | Atad2 | 9670 | 0.068 | -0.0550 | No |
| 56 | H2az1 | 9800 | 0.064 | -0.0583 | No |
| 57 | Psmc3ip | 10074 | 0.056 | -0.0680 | No |
| 58 | Hmmr | 10250 | 0.051 | -0.0737 | No |
| 59 | Cbx5 | 10257 | 0.051 | -0.0722 | No |
| 60 | Cse1l | 10281 | 0.050 | -0.0714 | No |
| 61 | Pttg1 | 10350 | 0.048 | -0.0726 | No |
| 62 | Aurka | 10416 | 0.046 | -0.0738 | No |
| 63 | Nudt21 | 10476 | 0.045 | -0.0747 | No |
| 64 | Tmpo | 10486 | 0.045 | -0.0735 | No |
| 65 | Prkdc | 10533 | 0.043 | -0.0740 | No |
| 66 | Pnn | 10598 | 0.041 | -0.0753 | No |
| 67 | Lmnb1 | 10777 | 0.037 | -0.0816 | No |
| 68 | Eed | 10813 | 0.036 | -0.0818 | No |
| 69 | Kif18b | 10871 | 0.034 | -0.0831 | No |
| 70 | Kif4 | 10939 | 0.032 | -0.0848 | No |
| 71 | Cnot9 | 11093 | 0.027 | -0.0904 | No |
| 72 | Nup153 | 11206 | 0.024 | -0.0944 | No |
| 73 | Wdr90 | 11248 | 0.023 | -0.0953 | No |
| 74 | Rad51ap1 | 11268 | 0.022 | -0.0954 | No |
| 75 | Donson | 11342 | 0.020 | -0.0978 | No |
| 76 | Wee1 | 11369 | 0.019 | -0.0982 | No |
| 77 | Nup107 | 11414 | 0.018 | -0.0995 | No |
| 78 | Cdkn1b | 11452 | 0.017 | -0.1005 | No |
| 79 | Pold3 | 11486 | 0.015 | -0.1014 | No |
| 80 | Eif2s1 | 11619 | 0.012 | -0.1066 | No |
| 81 | Smc6 | 11634 | 0.011 | -0.1068 | No |
| 82 | Zw10 | 11753 | 0.008 | -0.1116 | No |
| 83 | Cenpe | 11793 | 0.007 | -0.1130 | No |
| 84 | Rad21 | 11862 | 0.005 | -0.1157 | No |
| 85 | Pole4 | 12015 | 0.000 | -0.1222 | No |
| 86 | Trip13 | 12344 | -0.001 | -0.1362 | No |
| 87 | Spc25 | 12415 | -0.003 | -0.1390 | No |
| 88 | Birc5 | 12444 | -0.004 | -0.1401 | No |
| 89 | Rpa1 | 12447 | -0.004 | -0.1401 | No |
| 90 | Kif2c | 12614 | -0.007 | -0.1469 | No |
| 91 | Aurkb | 12662 | -0.009 | -0.1486 | No |
| 92 | Nasp | 12798 | -0.013 | -0.1539 | No |
| 93 | Brca1 | 12829 | -0.013 | -0.1547 | No |
| 94 | Prdx4 | 13136 | -0.022 | -0.1671 | No |
| 95 | Cdk1 | 13157 | -0.022 | -0.1671 | No |
| 96 | Nbn | 13193 | -0.023 | -0.1678 | No |
| 97 | Suv39h1 | 13230 | -0.025 | -0.1685 | No |
| 98 | Pms2 | 13270 | -0.026 | -0.1693 | No |
| 99 | Exosc8 | 13389 | -0.029 | -0.1733 | No |
| 100 | Ddx39a | 13422 | -0.029 | -0.1736 | No |
| 101 | Rad50 | 13514 | -0.032 | -0.1764 | No |
| 102 | Chek1 | 13519 | -0.032 | -0.1754 | No |
| 103 | Spc24 | 13583 | -0.034 | -0.1770 | No |
| 104 | Gins4 | 13705 | -0.038 | -0.1808 | No |
| 105 | Hells | 13757 | -0.040 | -0.1816 | No |
| 106 | Mcm2 | 13778 | -0.040 | -0.1810 | No |
| 107 | Gins3 | 13877 | -0.043 | -0.1837 | No |
| 108 | Rad51c | 13893 | -0.044 | -0.1829 | No |
| 109 | Brms1l | 13947 | -0.045 | -0.1835 | No |
| 110 | Gins1 | 14069 | -0.049 | -0.1870 | No |
| 111 | Hmga1b | 14150 | -0.051 | -0.1886 | No |
| 112 | Dck | 14195 | -0.052 | -0.1887 | No |
| 113 | Jpt1 | 14233 | -0.053 | -0.1884 | No |
| 114 | E2f8 | 14318 | -0.055 | -0.1901 | No |
| 115 | Prps1 | 14473 | -0.060 | -0.1946 | No |
| 116 | Chek2 | 14478 | -0.060 | -0.1927 | No |
| 117 | Cdca8 | 14494 | -0.060 | -0.1912 | No |
| 118 | Cdc25b | 14501 | -0.060 | -0.1893 | No |
| 119 | Ezh2 | 14551 | -0.062 | -0.1893 | No |
| 120 | Timeless | 14565 | -0.062 | -0.1876 | No |
| 121 | Orc6 | 14672 | -0.065 | -0.1899 | No |
| 122 | Ctcf | 14715 | -0.066 | -0.1894 | No |
| 123 | Phf5a | 14727 | -0.067 | -0.1875 | No |
| 124 | Nop56 | 14792 | -0.069 | -0.1878 | No |
| 125 | Rfc1 | 14841 | -0.071 | -0.1874 | No |
| 126 | Pop7 | 14924 | -0.073 | -0.1884 | No |
| 127 | Syncrip | 14957 | -0.074 | -0.1871 | No |
| 128 | Pds5b | 14965 | -0.075 | -0.1848 | No |
| 129 | Lsm8 | 14991 | -0.075 | -0.1833 | No |
| 130 | Tipin | 15347 | -0.088 | -0.1954 | No |
| 131 | Smc3 | 15700 | -0.097 | -0.2070 | Yes |
| 132 | Mcm4 | 15741 | -0.098 | -0.2053 | Yes |
| 133 | Orc2 | 15864 | -0.102 | -0.2069 | Yes |
| 134 | Dek | 15872 | -0.103 | -0.2036 | Yes |
| 135 | Top2a | 15907 | -0.104 | -0.2015 | Yes |
| 136 | Gspt1 | 16004 | -0.107 | -0.2018 | Yes |
| 137 | Rfc2 | 16019 | -0.108 | -0.1987 | Yes |
| 138 | Hmgb2 | 16067 | -0.109 | -0.1969 | Yes |
| 139 | Pa2g4 | 16093 | -0.110 | -0.1941 | Yes |
| 140 | Mthfd2 | 16122 | -0.111 | -0.1914 | Yes |
| 141 | Smc4 | 16169 | -0.113 | -0.1894 | Yes |
| 142 | Hnrnpd | 16242 | -0.115 | -0.1885 | Yes |
| 143 | Xrcc6 | 16291 | -0.117 | -0.1865 | Yes |
| 144 | Hmgb3 | 16449 | -0.122 | -0.1889 | Yes |
| 145 | Dclre1b | 16530 | -0.125 | -0.1880 | Yes |
| 146 | Cdkn3 | 16542 | -0.126 | -0.1840 | Yes |
| 147 | Trp53 | 16545 | -0.126 | -0.1797 | Yes |
| 148 | Smc1a | 16584 | -0.128 | -0.1769 | Yes |
| 149 | Plk4 | 16756 | -0.133 | -0.1796 | Yes |
| 150 | Msh2 | 16842 | -0.136 | -0.1784 | Yes |
| 151 | Cdca3 | 16852 | -0.136 | -0.1741 | Yes |
| 152 | Mcm3 | 16891 | -0.138 | -0.1709 | Yes |
| 153 | Lig1 | 17254 | -0.152 | -0.1810 | Yes |
| 154 | Ppp1r8 | 17364 | -0.155 | -0.1803 | Yes |
| 155 | Psip1 | 17563 | -0.162 | -0.1831 | Yes |
| 156 | Mcm6 | 17574 | -0.163 | -0.1778 | Yes |
| 157 | Rbbp7 | 17578 | -0.163 | -0.1722 | Yes |
| 158 | Srsf1 | 17936 | -0.177 | -0.1813 | Yes |
| 159 | Cdkn2c | 17951 | -0.177 | -0.1757 | Yes |
| 160 | Mad2l1 | 18353 | -0.191 | -0.1862 | Yes |
| 161 | Ssrp1 | 18508 | -0.198 | -0.1858 | Yes |
| 162 | Ncapd2 | 18521 | -0.199 | -0.1794 | Yes |
| 163 | Lyar | 18531 | -0.199 | -0.1729 | Yes |
| 164 | Hus1 | 18553 | -0.200 | -0.1668 | Yes |
| 165 | Ranbp1 | 18588 | -0.201 | -0.1612 | Yes |
| 166 | H2ax | 18597 | -0.201 | -0.1545 | Yes |
| 167 | Ing3 | 18615 | -0.202 | -0.1482 | Yes |
| 168 | Cdk4 | 18701 | -0.205 | -0.1447 | Yes |
| 169 | Nap1l1 | 18785 | -0.209 | -0.1409 | Yes |
| 170 | Luc7l3 | 18834 | -0.211 | -0.1356 | Yes |
| 171 | Ak2 | 18868 | -0.212 | -0.1296 | Yes |
| 172 | Cdc25a | 19060 | -0.221 | -0.1301 | Yes |
| 173 | Nme1 | 19181 | -0.225 | -0.1273 | Yes |
| 174 | Snrpb | 19476 | -0.239 | -0.1315 | Yes |
| 175 | Asf1a | 19502 | -0.241 | -0.1242 | Yes |
| 176 | Usp1 | 19521 | -0.241 | -0.1165 | Yes |
| 177 | Ubr7 | 19533 | -0.242 | -0.1086 | Yes |
| 178 | Cks1b | 19556 | -0.243 | -0.1010 | Yes |
| 179 | Rad1 | 19713 | -0.252 | -0.0989 | Yes |
| 180 | Rpa3 | 19781 | -0.256 | -0.0929 | Yes |
| 181 | Dut | 19793 | -0.256 | -0.0844 | Yes |
| 182 | Stmn1 | 19915 | -0.263 | -0.0804 | Yes |
| 183 | Ccne1 | 20119 | -0.275 | -0.0794 | Yes |
| 184 | Nolc1 | 20252 | -0.282 | -0.0752 | Yes |
| 185 | Ung | 20332 | -0.287 | -0.0686 | Yes |
| 186 | Rnaseh2a | 20716 | -0.307 | -0.0742 | Yes |
| 187 | Mcm7 | 20718 | -0.307 | -0.0636 | Yes |
| 188 | Paics | 21263 | -0.340 | -0.0749 | Yes |
| 189 | Tubb5 | 21645 | -0.365 | -0.0784 | Yes |
| 190 | Ran | 21753 | -0.374 | -0.0700 | Yes |
| 191 | Rfc3 | 22130 | -0.411 | -0.0717 | Yes |
| 192 | Ccnb2 | 22179 | -0.417 | -0.0592 | Yes |
| 193 | Rpa2 | 22220 | -0.422 | -0.0462 | Yes |
| 194 | Myc | 22533 | -0.459 | -0.0435 | Yes |
| 195 | Pold2 | 22883 | -0.513 | -0.0405 | Yes |
| 196 | Cdc20 | 23252 | -0.603 | -0.0351 | Yes |
| 197 | Dctpp1 | 23462 | -0.707 | -0.0194 | Yes |
| 198 | Cdkn1a | 23508 | -0.752 | 0.0050 | Yes |

