| Dataset | GMP.GMP.mono_Pheno.cls #Group6_versus_Group8.GMP.mono_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | GMP.mono_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 4 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | 0.23000482 |
| Normalized Enrichment Score (NES) | 1.1531613 |
| Nominal p-value | 0.1369863 |
| FDR q-value | 0.6971369 |
| FWER p-Value | 0.959 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Lgals3 | 3 | 1.760 | 0.0434 | Yes |
| 2 | Serpinb2 | 403 | 0.739 | 0.0446 | Yes |
| 3 | Gzmk | 479 | 0.716 | 0.0591 | Yes |
| 4 | Mmp15 | 528 | 0.703 | 0.0745 | Yes |
| 5 | Fcnb | 676 | 0.653 | 0.0843 | Yes |
| 6 | Serping1 | 687 | 0.645 | 0.0999 | Yes |
| 7 | Ctsc | 703 | 0.637 | 0.1149 | Yes |
| 8 | Tnfaip3 | 885 | 0.582 | 0.1216 | Yes |
| 9 | Cda | 1097 | 0.555 | 0.1263 | Yes |
| 10 | Dgkg | 1154 | 0.549 | 0.1375 | Yes |
| 11 | Plaur | 1171 | 0.548 | 0.1504 | Yes |
| 12 | Olr1 | 1445 | 0.519 | 0.1516 | Yes |
| 13 | Cfb | 1466 | 0.517 | 0.1635 | Yes |
| 14 | Pik3r5 | 1622 | 0.484 | 0.1689 | Yes |
| 15 | Prkcd | 1705 | 0.468 | 0.1769 | Yes |
| 16 | Clu | 1883 | 0.439 | 0.1803 | Yes |
| 17 | C3 | 1890 | 0.439 | 0.1908 | Yes |
| 18 | Sirt6 | 2043 | 0.424 | 0.1948 | Yes |
| 19 | Scg3 | 2158 | 0.409 | 0.2001 | Yes |
| 20 | Kcnip2 | 2191 | 0.407 | 0.2088 | Yes |
| 21 | Lrp1 | 2525 | 0.390 | 0.2042 | Yes |
| 22 | Timp1 | 2608 | 0.382 | 0.2101 | Yes |
| 23 | Cd36 | 3432 | 0.320 | 0.1830 | Yes |
| 24 | Gca | 3456 | 0.318 | 0.1899 | Yes |
| 25 | Brpf3 | 3513 | 0.313 | 0.1952 | Yes |
| 26 | Cpm | 3543 | 0.311 | 0.2017 | Yes |
| 27 | Lcp2 | 3687 | 0.301 | 0.2030 | Yes |
| 28 | Adam9 | 3808 | 0.293 | 0.2051 | Yes |
| 29 | L3mbtl4 | 3837 | 0.291 | 0.2111 | Yes |
| 30 | Prdm4 | 3851 | 0.290 | 0.2177 | Yes |
| 31 | Maff | 3999 | 0.281 | 0.2184 | Yes |
| 32 | Ctsh | 4103 | 0.275 | 0.2208 | Yes |
| 33 | Apoc1 | 4415 | 0.261 | 0.2140 | Yes |
| 34 | Hspa1a | 4551 | 0.253 | 0.2145 | Yes |
| 35 | Gata3 | 4604 | 0.250 | 0.2185 | Yes |
| 36 | F10 | 4610 | 0.250 | 0.2244 | Yes |
| 37 | Pdgfb | 4766 | 0.245 | 0.2239 | Yes |
| 38 | Ccl5 | 4778 | 0.244 | 0.2294 | Yes |
| 39 | Xpnpep1 | 4903 | 0.236 | 0.2300 | Yes |
| 40 | Sh2b3 | 5285 | 0.222 | 0.2193 | No |
| 41 | Irf7 | 5473 | 0.216 | 0.2166 | No |
| 42 | F3 | 5527 | 0.213 | 0.2196 | No |
| 43 | Tmprss6 | 5548 | 0.213 | 0.2240 | No |
| 44 | Ehd1 | 5634 | 0.208 | 0.2256 | No |
| 45 | Lyn | 5726 | 0.203 | 0.2267 | No |
| 46 | Cr2 | 6325 | 0.181 | 0.2057 | No |
| 47 | Lamp2 | 6486 | 0.175 | 0.2032 | No |
| 48 | Raf1 | 6515 | 0.173 | 0.2063 | No |
| 49 | Cdk5r1 | 6591 | 0.170 | 0.2073 | No |
| 50 | Lta4h | 6865 | 0.160 | 0.1996 | No |
| 51 | Serpinc1 | 6959 | 0.156 | 0.1995 | No |
| 52 | Kcnip3 | 7098 | 0.150 | 0.1973 | No |
| 53 | Usp8 | 7757 | 0.126 | 0.1724 | No |
| 54 | Plg | 7758 | 0.126 | 0.1755 | No |
| 55 | Pik3ca | 7816 | 0.125 | 0.1762 | No |
| 56 | Ctso | 7847 | 0.124 | 0.1779 | No |
| 57 | Gnai3 | 7864 | 0.123 | 0.1803 | No |
| 58 | Fcer1g | 7882 | 0.122 | 0.1826 | No |
| 59 | F7 | 8232 | 0.111 | 0.1705 | No |
| 60 | Jak2 | 8385 | 0.107 | 0.1666 | No |
| 61 | Atox1 | 8594 | 0.099 | 0.1602 | No |
| 62 | Psen1 | 8724 | 0.095 | 0.1571 | No |
| 63 | Casp9 | 8986 | 0.088 | 0.1481 | No |
| 64 | Usp15 | 9078 | 0.085 | 0.1463 | No |
| 65 | Ppp4c | 9112 | 0.085 | 0.1470 | No |
| 66 | Irf2 | 9467 | 0.074 | 0.1338 | No |
| 67 | Gngt2 | 9576 | 0.071 | 0.1309 | No |
| 68 | Dock10 | 9622 | 0.069 | 0.1307 | No |
| 69 | Casp7 | 9665 | 0.068 | 0.1306 | No |
| 70 | Rhog | 9735 | 0.066 | 0.1293 | No |
| 71 | F5 | 9804 | 0.064 | 0.1280 | No |
| 72 | Akap10 | 9996 | 0.059 | 0.1213 | No |
| 73 | Pcsk9 | 10095 | 0.056 | 0.1185 | No |
| 74 | Lck | 10205 | 0.052 | 0.1151 | No |
| 75 | C9 | 10312 | 0.049 | 0.1118 | No |
| 76 | Dock4 | 10355 | 0.048 | 0.1112 | No |
| 77 | Vcpip1 | 10364 | 0.048 | 0.1121 | No |
| 78 | Gng2 | 10366 | 0.048 | 0.1132 | No |
| 79 | Pla2g4a | 10487 | 0.045 | 0.1092 | No |
| 80 | Dyrk2 | 10863 | 0.034 | 0.0940 | No |
| 81 | Prep | 10889 | 0.033 | 0.0938 | No |
| 82 | Rabif | 10898 | 0.033 | 0.0943 | No |
| 83 | Cblb | 11124 | 0.026 | 0.0853 | No |
| 84 | Kif2a | 11321 | 0.021 | 0.0775 | No |
| 85 | Was | 11526 | 0.014 | 0.0691 | No |
| 86 | Mmp14 | 11676 | 0.010 | 0.0630 | No |
| 87 | Ang | 11886 | 0.004 | 0.0542 | No |
| 88 | Cd46 | 11908 | 0.003 | 0.0534 | No |
| 89 | Usp16 | 11936 | 0.002 | 0.0523 | No |
| 90 | Gzmb | 12044 | 0.000 | 0.0478 | No |
| 91 | F8 | 12331 | -0.000 | 0.0356 | No |
| 92 | Hnf4a | 12361 | -0.001 | 0.0344 | No |
| 93 | Usp14 | 12376 | -0.002 | 0.0338 | No |
| 94 | Ppp2cb | 12473 | -0.004 | 0.0298 | No |
| 95 | Plek | 13175 | -0.023 | 0.0005 | No |
| 96 | Stx4a | 13267 | -0.026 | -0.0027 | No |
| 97 | Gpd2 | 13383 | -0.029 | -0.0069 | No |
| 98 | Rbsn | 13588 | -0.034 | -0.0148 | No |
| 99 | Anxa5 | 13692 | -0.038 | -0.0182 | No |
| 100 | Hspa5 | 13744 | -0.039 | -0.0195 | No |
| 101 | Grb2 | 13796 | -0.041 | -0.0206 | No |
| 102 | Psmb9 | 13851 | -0.042 | -0.0219 | No |
| 103 | Fn1 | 14020 | -0.047 | -0.0279 | No |
| 104 | Cpq | 14058 | -0.048 | -0.0283 | No |
| 105 | Src | 14386 | -0.057 | -0.0408 | No |
| 106 | Prcp | 14445 | -0.059 | -0.0418 | No |
| 107 | Dgkh | 14570 | -0.063 | -0.0455 | No |
| 108 | Notch4 | 14776 | -0.069 | -0.0526 | No |
| 109 | Ctsl | 15065 | -0.078 | -0.0629 | No |
| 110 | Ltf | 15109 | -0.079 | -0.0628 | No |
| 111 | Fyn | 15125 | -0.080 | -0.0615 | No |
| 112 | Pdp1 | 15154 | -0.081 | -0.0607 | No |
| 113 | Prss36 | 15374 | -0.088 | -0.0678 | No |
| 114 | Pclo | 15694 | -0.097 | -0.0790 | No |
| 115 | Rnf4 | 15913 | -0.104 | -0.0858 | No |
| 116 | Gmfb | 16077 | -0.109 | -0.0900 | No |
| 117 | Cfh | 16154 | -0.112 | -0.0905 | No |
| 118 | Cdh13 | 16261 | -0.115 | -0.0922 | No |
| 119 | Ctsb | 16290 | -0.117 | -0.0905 | No |
| 120 | Me1 | 16738 | -0.133 | -0.1062 | No |
| 121 | Dusp5 | 16753 | -0.133 | -0.1035 | No |
| 122 | Plscr1 | 16799 | -0.135 | -0.1021 | No |
| 123 | Lipa | 16807 | -0.135 | -0.0991 | No |
| 124 | Csrp1 | 17006 | -0.142 | -0.1040 | No |
| 125 | Cebpb | 17058 | -0.144 | -0.1027 | No |
| 126 | Gnai2 | 17366 | -0.155 | -0.1119 | No |
| 127 | Irf1 | 17602 | -0.164 | -0.1179 | No |
| 128 | Pik3cg | 17675 | -0.167 | -0.1168 | No |
| 129 | Pfn1 | 17870 | -0.174 | -0.1208 | No |
| 130 | Klkb1 | 17911 | -0.176 | -0.1181 | No |
| 131 | Fdx1 | 18449 | -0.196 | -0.1362 | No |
| 132 | Pim1 | 18467 | -0.196 | -0.1321 | No |
| 133 | Casp1 | 18513 | -0.198 | -0.1291 | No |
| 134 | Actn2 | 18731 | -0.207 | -0.1332 | No |
| 135 | Calm3 | 18956 | -0.217 | -0.1374 | No |
| 136 | Kynu | 19005 | -0.219 | -0.1341 | No |
| 137 | Gp1ba | 19057 | -0.221 | -0.1308 | No |
| 138 | Rasgrp1 | 19119 | -0.222 | -0.1279 | No |
| 139 | Gp9 | 19525 | -0.241 | -0.1392 | No |
| 140 | Lap3 | 19555 | -0.243 | -0.1344 | No |
| 141 | Lgmn | 19716 | -0.252 | -0.1350 | No |
| 142 | Car2 | 20228 | -0.281 | -0.1499 | No |
| 143 | Calm1 | 20269 | -0.283 | -0.1446 | No |
| 144 | Ctsd | 20306 | -0.285 | -0.1391 | No |
| 145 | Itgam | 20327 | -0.287 | -0.1328 | No |
| 146 | Ctss | 20531 | -0.296 | -0.1342 | No |
| 147 | C2 | 20673 | -0.304 | -0.1327 | No |
| 148 | Dock9 | 20729 | -0.308 | -0.1274 | No |
| 149 | Msrb1 | 20796 | -0.313 | -0.1225 | No |
| 150 | C1qc | 20872 | -0.318 | -0.1178 | No |
| 151 | F2 | 20913 | -0.319 | -0.1117 | No |
| 152 | Pla2g7 | 20964 | -0.320 | -0.1059 | No |
| 153 | Zeb1 | 21028 | -0.325 | -0.1006 | No |
| 154 | Casp4 | 21261 | -0.340 | -0.1020 | No |
| 155 | Timp2 | 21620 | -0.363 | -0.1083 | No |
| 156 | Casp3 | 21760 | -0.375 | -0.1050 | No |
| 157 | Dusp6 | 21777 | -0.376 | -0.0964 | No |
| 158 | Gnb4 | 21825 | -0.380 | -0.0890 | No |
| 159 | Phex | 21993 | -0.397 | -0.0863 | No |
| 160 | Dpp4 | 22010 | -0.398 | -0.0771 | No |
| 161 | Gnb2 | 22121 | -0.410 | -0.0717 | No |
| 162 | Spock2 | 22147 | -0.413 | -0.0626 | No |
| 163 | Cp | 22156 | -0.414 | -0.0527 | No |
| 164 | Zfpm2 | 22603 | -0.470 | -0.0601 | No |
| 165 | Rce1 | 22773 | -0.495 | -0.0551 | No |
| 166 | Col4a2 | 23199 | -0.588 | -0.0586 | No |
| 167 | S100a9 | 23294 | -0.617 | -0.0474 | No |
| 168 | S100a13 | 23406 | -0.674 | -0.0355 | No |
| 169 | Tfpi2 | 23527 | -0.776 | -0.0214 | No |
| 170 | Mmp8 | 23614 | -1.032 | 0.0004 | No |

