| Dataset | GMP.GMP.mono_Pheno.cls #Group3_versus_Group4.GMP.mono_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | -0.18215758 |
| Normalized Enrichment Score (NES) | -0.75726825 |
| Nominal p-value | 0.8896247 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tnfaip3 | 122 | 0.850 | 0.0210 | No |
| 2 | Gp9 | 167 | 0.805 | 0.0440 | No |
| 3 | Mmp15 | 296 | 0.705 | 0.0603 | No |
| 4 | Rasgrp1 | 337 | 0.686 | 0.0798 | No |
| 5 | Dusp6 | 488 | 0.634 | 0.0930 | No |
| 6 | Serping1 | 715 | 0.566 | 0.1008 | No |
| 7 | Ang | 930 | 0.520 | 0.1077 | No |
| 8 | Gata3 | 1967 | 0.394 | 0.0757 | No |
| 9 | Tmprss6 | 2308 | 0.372 | 0.0727 | No |
| 10 | Car2 | 2584 | 0.353 | 0.0719 | No |
| 11 | Notch4 | 2932 | 0.324 | 0.0671 | No |
| 12 | Cd36 | 2977 | 0.320 | 0.0751 | No |
| 13 | Dusp5 | 3087 | 0.314 | 0.0801 | No |
| 14 | F7 | 3130 | 0.311 | 0.0879 | No |
| 15 | Pcsk9 | 3347 | 0.295 | 0.0878 | No |
| 16 | Cfh | 3362 | 0.295 | 0.0963 | No |
| 17 | Serpinc1 | 3565 | 0.290 | 0.0967 | No |
| 18 | C2 | 3700 | 0.280 | 0.0996 | No |
| 19 | Timp1 | 3929 | 0.271 | 0.0983 | No |
| 20 | Lap3 | 4870 | 0.230 | 0.0653 | No |
| 21 | Actn2 | 4991 | 0.224 | 0.0671 | No |
| 22 | Ctsd | 5047 | 0.221 | 0.0716 | No |
| 23 | Fcnb | 5053 | 0.221 | 0.0782 | No |
| 24 | Klkb1 | 5073 | 0.220 | 0.0842 | No |
| 25 | Fyn | 5141 | 0.217 | 0.0881 | No |
| 26 | Lck | 5321 | 0.209 | 0.0869 | No |
| 27 | Pla2g7 | 5437 | 0.204 | 0.0883 | No |
| 28 | Rnf4 | 5473 | 0.203 | 0.0930 | No |
| 29 | Zfpm2 | 5480 | 0.203 | 0.0990 | No |
| 30 | F5 | 5538 | 0.199 | 0.1028 | No |
| 31 | Anxa5 | 5676 | 0.193 | 0.1029 | No |
| 32 | Cp | 5772 | 0.190 | 0.1047 | No |
| 33 | Usp8 | 5969 | 0.182 | 0.1020 | No |
| 34 | Cd46 | 5991 | 0.181 | 0.1067 | No |
| 35 | Maff | 6001 | 0.181 | 0.1118 | No |
| 36 | Hnf4a | 6016 | 0.180 | 0.1168 | No |
| 37 | S100a9 | 6296 | 0.171 | 0.1102 | No |
| 38 | Rhog | 6430 | 0.171 | 0.1098 | No |
| 39 | Lgmn | 6460 | 0.170 | 0.1138 | No |
| 40 | Kcnip3 | 6632 | 0.162 | 0.1115 | No |
| 41 | Plek | 6669 | 0.160 | 0.1150 | No |
| 42 | Prkcd | 6702 | 0.159 | 0.1185 | No |
| 43 | Olr1 | 6758 | 0.157 | 0.1210 | No |
| 44 | Phex | 6794 | 0.155 | 0.1243 | No |
| 45 | Pik3cg | 6834 | 0.154 | 0.1274 | No |
| 46 | Plaur | 6892 | 0.152 | 0.1297 | No |
| 47 | Src | 6898 | 0.152 | 0.1341 | No |
| 48 | Rce1 | 6928 | 0.150 | 0.1375 | No |
| 49 | Cfb | 6932 | 0.150 | 0.1421 | No |
| 50 | Tfpi2 | 7043 | 0.147 | 0.1419 | No |
| 51 | Lipa | 7248 | 0.139 | 0.1375 | No |
| 52 | Xpnpep1 | 7359 | 0.135 | 0.1370 | No |
| 53 | Akap10 | 7434 | 0.132 | 0.1379 | No |
| 54 | Was | 7496 | 0.130 | 0.1393 | No |
| 55 | Fn1 | 7502 | 0.130 | 0.1431 | No |
| 56 | C9 | 7630 | 0.126 | 0.1416 | No |
| 57 | Casp4 | 8065 | 0.112 | 0.1266 | No |
| 58 | Ppp2cb | 8336 | 0.106 | 0.1183 | No |
| 59 | Adam9 | 8522 | 0.100 | 0.1135 | No |
| 60 | Dyrk2 | 8620 | 0.097 | 0.1124 | No |
| 61 | Gnb4 | 8917 | 0.088 | 0.1025 | No |
| 62 | Gnai3 | 8970 | 0.086 | 0.1029 | No |
| 63 | Gzmb | 9085 | 0.083 | 0.1006 | No |
| 64 | Casp9 | 9341 | 0.077 | 0.0921 | No |
| 65 | Ppp4c | 9469 | 0.073 | 0.0890 | No |
| 66 | Brpf3 | 9577 | 0.071 | 0.0866 | No |
| 67 | Dgkh | 9604 | 0.070 | 0.0876 | No |
| 68 | Irf2 | 9617 | 0.070 | 0.0893 | No |
| 69 | Dock9 | 9705 | 0.067 | 0.0877 | No |
| 70 | Lamp2 | 9755 | 0.066 | 0.0876 | No |
| 71 | Gpd2 | 9757 | 0.066 | 0.0896 | No |
| 72 | C3 | 10111 | 0.057 | 0.0763 | No |
| 73 | Psmb9 | 10165 | 0.055 | 0.0758 | No |
| 74 | Csrp1 | 10458 | 0.047 | 0.0648 | No |
| 75 | Ctss | 10583 | 0.045 | 0.0609 | No |
| 76 | Grb2 | 10634 | 0.043 | 0.0601 | No |
| 77 | Stx4a | 10673 | 0.042 | 0.0597 | No |
| 78 | Fcer1g | 10876 | 0.037 | 0.0523 | No |
| 79 | Cr2 | 10930 | 0.036 | 0.0511 | No |
| 80 | Pdp1 | 11126 | 0.030 | 0.0437 | No |
| 81 | Hspa5 | 11174 | 0.028 | 0.0426 | No |
| 82 | Zeb1 | 11402 | 0.023 | 0.0336 | No |
| 83 | Atox1 | 11507 | 0.020 | 0.0298 | No |
| 84 | Pla2g4a | 11823 | 0.012 | 0.0167 | No |
| 85 | Gmfb | 11847 | 0.012 | 0.0161 | No |
| 86 | Mmp8 | 12004 | 0.008 | 0.0097 | No |
| 87 | Ctsh | 12033 | 0.007 | 0.0087 | No |
| 88 | Psen1 | 12232 | 0.002 | 0.0004 | No |
| 89 | Calm3 | 12717 | -0.001 | -0.0202 | No |
| 90 | Pclo | 12870 | -0.005 | -0.0265 | No |
| 91 | Plscr1 | 13041 | -0.010 | -0.0335 | No |
| 92 | Irf7 | 13233 | -0.015 | -0.0412 | No |
| 93 | Dgkg | 13241 | -0.015 | -0.0410 | No |
| 94 | Casp7 | 13340 | -0.017 | -0.0447 | No |
| 95 | Pfn1 | 13398 | -0.019 | -0.0465 | No |
| 96 | Jak2 | 13404 | -0.019 | -0.0461 | No |
| 97 | Usp15 | 13420 | -0.019 | -0.0462 | No |
| 98 | Cblb | 13492 | -0.021 | -0.0486 | No |
| 99 | Casp1 | 13553 | -0.023 | -0.0504 | No |
| 100 | Lta4h | 13638 | -0.025 | -0.0532 | No |
| 101 | Rbsn | 13738 | -0.027 | -0.0566 | No |
| 102 | Prep | 13747 | -0.027 | -0.0561 | No |
| 103 | Timp2 | 13967 | -0.033 | -0.0644 | No |
| 104 | Mmp14 | 14092 | -0.036 | -0.0686 | No |
| 105 | Raf1 | 14261 | -0.040 | -0.0745 | No |
| 106 | Sh2b3 | 14293 | -0.041 | -0.0746 | No |
| 107 | Gngt2 | 14556 | -0.047 | -0.0843 | No |
| 108 | Pik3ca | 14594 | -0.048 | -0.0844 | No |
| 109 | F3 | 14720 | -0.052 | -0.0881 | No |
| 110 | Pdgfb | 15350 | -0.069 | -0.1128 | No |
| 111 | Usp14 | 15634 | -0.076 | -0.1225 | No |
| 112 | Serpinb2 | 15877 | -0.082 | -0.1303 | No |
| 113 | Cpm | 15987 | -0.086 | -0.1323 | No |
| 114 | F10 | 16233 | -0.093 | -0.1399 | No |
| 115 | Gnai2 | 16369 | -0.095 | -0.1427 | No |
| 116 | Usp16 | 16692 | -0.105 | -0.1532 | No |
| 117 | Vcpip1 | 16703 | -0.105 | -0.1503 | No |
| 118 | Msrb1 | 16901 | -0.112 | -0.1553 | No |
| 119 | Casp3 | 16980 | -0.114 | -0.1551 | No |
| 120 | Kif2a | 16995 | -0.115 | -0.1521 | No |
| 121 | Ctsb | 17118 | -0.119 | -0.1537 | No |
| 122 | Cda | 17182 | -0.121 | -0.1526 | No |
| 123 | Prdm4 | 17256 | -0.123 | -0.1519 | No |
| 124 | Gng2 | 17448 | -0.130 | -0.1560 | No |
| 125 | Scg3 | 17807 | -0.141 | -0.1669 | No |
| 126 | Ehd1 | 17873 | -0.143 | -0.1653 | No |
| 127 | Lyn | 17980 | -0.147 | -0.1653 | No |
| 128 | Dock10 | 18024 | -0.149 | -0.1625 | No |
| 129 | Lcp2 | 18111 | -0.152 | -0.1615 | No |
| 130 | Clu | 18350 | -0.161 | -0.1667 | No |
| 131 | Cdk5r1 | 18508 | -0.167 | -0.1682 | No |
| 132 | Gzmk | 18836 | -0.182 | -0.1765 | Yes |
| 133 | Ctso | 18840 | -0.182 | -0.1710 | Yes |
| 134 | Calm1 | 18864 | -0.183 | -0.1664 | Yes |
| 135 | Pim1 | 18958 | -0.187 | -0.1646 | Yes |
| 136 | Ctsc | 19031 | -0.190 | -0.1618 | Yes |
| 137 | Ctsl | 19089 | -0.193 | -0.1583 | Yes |
| 138 | Irf1 | 19108 | -0.193 | -0.1531 | Yes |
| 139 | Kcnip2 | 19220 | -0.198 | -0.1517 | Yes |
| 140 | Sirt6 | 19418 | -0.208 | -0.1537 | Yes |
| 141 | Apoc1 | 19594 | -0.215 | -0.1545 | Yes |
| 142 | Dock4 | 19662 | -0.218 | -0.1506 | Yes |
| 143 | F2 | 19692 | -0.219 | -0.1451 | Yes |
| 144 | Me1 | 19818 | -0.219 | -0.1437 | Yes |
| 145 | Itgam | 19833 | -0.220 | -0.1375 | Yes |
| 146 | Cebpb | 19868 | -0.223 | -0.1320 | Yes |
| 147 | F8 | 20072 | -0.233 | -0.1335 | Yes |
| 148 | Pik3r5 | 20128 | -0.236 | -0.1286 | Yes |
| 149 | Gca | 20195 | -0.240 | -0.1240 | Yes |
| 150 | Kynu | 20333 | -0.249 | -0.1221 | Yes |
| 151 | Prss36 | 20545 | -0.260 | -0.1231 | Yes |
| 152 | Gnb2 | 20616 | -0.262 | -0.1180 | Yes |
| 153 | Plg | 21067 | -0.288 | -0.1283 | Yes |
| 154 | Gp1ba | 21325 | -0.307 | -0.1298 | Yes |
| 155 | Cpq | 21566 | -0.318 | -0.1302 | Yes |
| 156 | Prcp | 21600 | -0.320 | -0.1217 | Yes |
| 157 | Lgals3 | 21679 | -0.326 | -0.1150 | Yes |
| 158 | Rabif | 21693 | -0.327 | -0.1054 | Yes |
| 159 | Ltf | 22032 | -0.357 | -0.1088 | Yes |
| 160 | Cdh13 | 22112 | -0.366 | -0.1009 | Yes |
| 161 | Lrp1 | 22380 | -0.396 | -0.1001 | Yes |
| 162 | Spock2 | 22921 | -0.481 | -0.1083 | Yes |
| 163 | L3mbtl4 | 22996 | -0.493 | -0.0962 | Yes |
| 164 | C1qc | 23161 | -0.522 | -0.0871 | Yes |
| 165 | Dpp4 | 23167 | -0.524 | -0.0711 | Yes |
| 166 | Ccl5 | 23192 | -0.533 | -0.0557 | Yes |
| 167 | S100a13 | 23211 | -0.540 | -0.0398 | Yes |
| 168 | Fdx1 | 23235 | -0.548 | -0.0239 | Yes |
| 169 | Col4a2 | 23456 | -0.650 | -0.0132 | Yes |
| 170 | Hspa1a | 23470 | -0.658 | 0.0066 | Yes |

