| Dataset | GMP.GMP.mono_Pheno.cls #Group3_versus_Group4.GMP.mono_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.23423651 |
| Normalized Enrichment Score (NES) | -0.8402738 |
| Nominal p-value | 0.6714579 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Stab1 | 8 | 1.257 | 0.0412 | No |
| 2 | Lif | 336 | 0.686 | 0.0499 | No |
| 3 | Capg | 376 | 0.670 | 0.0704 | No |
| 4 | Cdkn2a | 636 | 0.583 | 0.0786 | No |
| 5 | Fas | 1746 | 0.419 | 0.0452 | No |
| 6 | Il10 | 1766 | 0.417 | 0.0582 | No |
| 7 | Il18 | 1781 | 0.414 | 0.0713 | No |
| 8 | Il2rb | 2320 | 0.372 | 0.0606 | No |
| 9 | Thy1 | 2381 | 0.368 | 0.0702 | No |
| 10 | Cd80 | 2811 | 0.334 | 0.0630 | No |
| 11 | Ets1 | 3216 | 0.305 | 0.0558 | No |
| 12 | Traf2 | 3550 | 0.291 | 0.0513 | No |
| 13 | Cd40 | 3651 | 0.284 | 0.0564 | No |
| 14 | Pf4 | 3687 | 0.281 | 0.0642 | No |
| 15 | C2 | 3700 | 0.280 | 0.0729 | No |
| 16 | Ccr5 | 3706 | 0.280 | 0.0820 | No |
| 17 | Ly75 | 3740 | 0.279 | 0.0898 | No |
| 18 | Timp1 | 3929 | 0.271 | 0.0907 | No |
| 19 | Il27ra | 4244 | 0.256 | 0.0858 | No |
| 20 | Mmp9 | 4292 | 0.254 | 0.0922 | No |
| 21 | Irf4 | 4694 | 0.238 | 0.0830 | No |
| 22 | Gcnt1 | 4987 | 0.224 | 0.0780 | No |
| 23 | Itk | 5305 | 0.209 | 0.0714 | No |
| 24 | Lck | 5321 | 0.209 | 0.0776 | No |
| 25 | Prkcb | 5381 | 0.206 | 0.0819 | No |
| 26 | Il2rg | 5475 | 0.203 | 0.0846 | No |
| 27 | Tnf | 5557 | 0.199 | 0.0878 | No |
| 28 | Rpl3l | 5650 | 0.195 | 0.0903 | No |
| 29 | Apbb1 | 5847 | 0.187 | 0.0881 | No |
| 30 | Cd3d | 6097 | 0.177 | 0.0833 | No |
| 31 | Ache | 6528 | 0.167 | 0.0705 | No |
| 32 | Elane | 6714 | 0.159 | 0.0678 | No |
| 33 | Trat1 | 6826 | 0.154 | 0.0682 | No |
| 34 | Egfr | 7422 | 0.133 | 0.0472 | No |
| 35 | Itgb2 | 7431 | 0.132 | 0.0513 | No |
| 36 | Was | 7496 | 0.130 | 0.0528 | No |
| 37 | Bcat1 | 7506 | 0.130 | 0.0568 | No |
| 38 | Prkcg | 7780 | 0.121 | 0.0491 | No |
| 39 | Flna | 7799 | 0.121 | 0.0524 | No |
| 40 | Cd74 | 7834 | 0.120 | 0.0549 | No |
| 41 | Eif3d | 7878 | 0.118 | 0.0569 | No |
| 42 | Cd96 | 7944 | 0.116 | 0.0580 | No |
| 43 | Zap70 | 8332 | 0.106 | 0.0450 | No |
| 44 | Tlr6 | 8469 | 0.102 | 0.0426 | No |
| 45 | Il4 | 8754 | 0.093 | 0.0336 | No |
| 46 | Il4ra | 8900 | 0.088 | 0.0303 | No |
| 47 | Mrpl3 | 8984 | 0.086 | 0.0296 | No |
| 48 | Akt1 | 9034 | 0.084 | 0.0303 | No |
| 49 | Galnt1 | 9052 | 0.084 | 0.0323 | No |
| 50 | Gzmb | 9085 | 0.083 | 0.0337 | No |
| 51 | Irf8 | 9351 | 0.076 | 0.0249 | No |
| 52 | Il18rap | 9679 | 0.068 | 0.0133 | No |
| 53 | Hcls1 | 9700 | 0.068 | 0.0146 | No |
| 54 | Cd247 | 9814 | 0.064 | 0.0119 | No |
| 55 | Srgn | 10053 | 0.058 | 0.0037 | No |
| 56 | Ube2n | 10192 | 0.055 | -0.0004 | No |
| 57 | Il12a | 10290 | 0.052 | -0.0028 | No |
| 58 | Cd79a | 10292 | 0.051 | -0.0011 | No |
| 59 | Ccr1 | 10318 | 0.051 | -0.0005 | No |
| 60 | St8sia4 | 10401 | 0.049 | -0.0024 | No |
| 61 | Ncf4 | 10413 | 0.049 | -0.0013 | No |
| 62 | Abce1 | 10418 | 0.048 | 0.0002 | No |
| 63 | Ctss | 10583 | 0.045 | -0.0054 | No |
| 64 | Csk | 10730 | 0.041 | -0.0102 | No |
| 65 | Map3k7 | 11144 | 0.029 | -0.0269 | No |
| 66 | Hdac9 | 11188 | 0.028 | -0.0278 | No |
| 67 | Wars1 | 11336 | 0.025 | -0.0332 | No |
| 68 | Rpl9 | 11352 | 0.024 | -0.0331 | No |
| 69 | Tapbp | 11514 | 0.020 | -0.0393 | No |
| 70 | Eif3a | 11570 | 0.019 | -0.0410 | No |
| 71 | Elf4 | 11609 | 0.018 | -0.0420 | No |
| 72 | Cd4 | 11612 | 0.018 | -0.0415 | No |
| 73 | Itgal | 11624 | 0.017 | -0.0414 | No |
| 74 | Icosl | 11692 | 0.016 | -0.0438 | No |
| 75 | Abi1 | 11722 | 0.015 | -0.0445 | No |
| 76 | Inhba | 11756 | 0.014 | -0.0454 | No |
| 77 | Il16 | 11808 | 0.012 | -0.0472 | No |
| 78 | Nck1 | 11821 | 0.012 | -0.0473 | No |
| 79 | Il1b | 12347 | 0.000 | -0.0697 | No |
| 80 | Dyrk3 | 12819 | -0.004 | -0.0896 | No |
| 81 | Ccr2 | 12837 | -0.005 | -0.0902 | No |
| 82 | Ifngr2 | 13136 | -0.012 | -0.1025 | No |
| 83 | Irf7 | 13233 | -0.015 | -0.1061 | No |
| 84 | Eif4g3 | 13251 | -0.015 | -0.1063 | No |
| 85 | Fcgr2b | 13390 | -0.019 | -0.1116 | No |
| 86 | Jak2 | 13404 | -0.019 | -0.1115 | No |
| 87 | Ptprc | 13421 | -0.019 | -0.1116 | No |
| 88 | Socs5 | 13472 | -0.021 | -0.1130 | No |
| 89 | Igsf6 | 13482 | -0.021 | -0.1127 | No |
| 90 | Brca1 | 14005 | -0.034 | -0.1338 | No |
| 91 | Ifngr1 | 14302 | -0.041 | -0.1451 | No |
| 92 | Cd47 | 14409 | -0.044 | -0.1481 | No |
| 93 | Eif3j1 | 14819 | -0.055 | -0.1637 | No |
| 94 | Tpd52 | 14831 | -0.055 | -0.1624 | No |
| 95 | Tap1 | 14978 | -0.059 | -0.1667 | No |
| 96 | Bcl3 | 15064 | -0.062 | -0.1682 | No |
| 97 | Ly86 | 15088 | -0.062 | -0.1672 | No |
| 98 | Csf1 | 15104 | -0.063 | -0.1657 | No |
| 99 | Cd1d2 | 15184 | -0.065 | -0.1669 | No |
| 100 | Ikbkb | 15606 | -0.075 | -0.1824 | No |
| 101 | H2-Ob | 15744 | -0.078 | -0.1857 | No |
| 102 | Rps3a1 | 15870 | -0.082 | -0.1883 | No |
| 103 | Cd86 | 15931 | -0.084 | -0.1881 | No |
| 104 | Ptpn6 | 16230 | -0.093 | -0.1977 | No |
| 105 | Psmb10 | 16574 | -0.101 | -0.2090 | No |
| 106 | Ccnd2 | 16577 | -0.101 | -0.2057 | No |
| 107 | Cfp | 16699 | -0.105 | -0.2074 | No |
| 108 | B2m | 16742 | -0.107 | -0.2057 | No |
| 109 | Il12rb1 | 16836 | -0.110 | -0.2060 | No |
| 110 | Eif5a | 17161 | -0.120 | -0.2158 | No |
| 111 | Mtif2 | 17234 | -0.123 | -0.2148 | No |
| 112 | Hif1a | 17565 | -0.134 | -0.2245 | No |
| 113 | Stat4 | 17674 | -0.136 | -0.2246 | No |
| 114 | Cd28 | 17692 | -0.137 | -0.2208 | No |
| 115 | Rps9 | 17837 | -0.142 | -0.2222 | No |
| 116 | Crtam | 17850 | -0.143 | -0.2180 | No |
| 117 | Lyn | 17980 | -0.147 | -0.2187 | No |
| 118 | Lcp2 | 18111 | -0.152 | -0.2192 | No |
| 119 | Glmn | 18114 | -0.152 | -0.2143 | No |
| 120 | Map4k1 | 18143 | -0.153 | -0.2104 | No |
| 121 | Tgfb1 | 18253 | -0.157 | -0.2099 | No |
| 122 | Npm1 | 18432 | -0.164 | -0.2120 | No |
| 123 | Degs1 | 18603 | -0.172 | -0.2136 | No |
| 124 | H2-Aa | 18842 | -0.182 | -0.2177 | No |
| 125 | H2-DMa | 19231 | -0.199 | -0.2277 | Yes |
| 126 | Il15 | 19259 | -0.200 | -0.2222 | Yes |
| 127 | Gpr65 | 19443 | -0.209 | -0.2231 | Yes |
| 128 | Ifnar2 | 19507 | -0.213 | -0.2187 | Yes |
| 129 | F2 | 19692 | -0.219 | -0.2194 | Yes |
| 130 | Tap2 | 19848 | -0.221 | -0.2187 | Yes |
| 131 | Tlr2 | 20084 | -0.233 | -0.2210 | Yes |
| 132 | Il2ra | 20257 | -0.244 | -0.2202 | Yes |
| 133 | Ncr1 | 20317 | -0.248 | -0.2146 | Yes |
| 134 | Nlrp3 | 20376 | -0.252 | -0.2087 | Yes |
| 135 | Spi1 | 20381 | -0.252 | -0.2006 | Yes |
| 136 | Nos2 | 20840 | -0.277 | -0.2109 | Yes |
| 137 | Acvr2a | 21260 | -0.302 | -0.2188 | Yes |
| 138 | Il7 | 21316 | -0.306 | -0.2110 | Yes |
| 139 | Nme1 | 21538 | -0.316 | -0.2100 | Yes |
| 140 | Bcl10 | 21603 | -0.320 | -0.2021 | Yes |
| 141 | Ube2d1 | 21658 | -0.325 | -0.1937 | Yes |
| 142 | Tgfb2 | 21915 | -0.347 | -0.1932 | Yes |
| 143 | Fgr | 22048 | -0.358 | -0.1870 | Yes |
| 144 | Ripk2 | 22155 | -0.371 | -0.1792 | Yes |
| 145 | Il2 | 22164 | -0.372 | -0.1672 | Yes |
| 146 | Tlr1 | 22190 | -0.374 | -0.1560 | Yes |
| 147 | Socs1 | 22218 | -0.378 | -0.1446 | Yes |
| 148 | Ccnd3 | 22362 | -0.394 | -0.1377 | Yes |
| 149 | Tlr3 | 22404 | -0.399 | -0.1263 | Yes |
| 150 | F2r | 22513 | -0.417 | -0.1171 | Yes |
| 151 | Icam1 | 22862 | -0.467 | -0.1165 | Yes |
| 152 | H2-DMb2 | 22865 | -0.468 | -0.1012 | Yes |
| 153 | Cxcr3 | 23011 | -0.494 | -0.0910 | Yes |
| 154 | H2-Oa | 23070 | -0.502 | -0.0769 | Yes |
| 155 | Stat1 | 23160 | -0.522 | -0.0635 | Yes |
| 156 | Ccl5 | 23192 | -0.533 | -0.0472 | Yes |
| 157 | Klrd1 | 23363 | -0.602 | -0.0346 | Yes |
| 158 | Ltb | 23471 | -0.658 | -0.0174 | Yes |
| 159 | Il11 | 23538 | -0.722 | 0.0037 | Yes |

