Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group2_versus_Group4.GMP.mono_Pheno.cls #Group2_versus_Group4_repos
Phenotype	GMP.mono_Pheno.cls#Group2_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.20174508
Normalized Enrichment Score (NES)	-0.8836221
Nominal p-value	0.626327
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Hexim1	24	1.030	0.0195	No
2	Stom	109	0.838	0.0327	No
3	Plk2	161	0.794	0.0464	No
4	Osgin1	280	0.732	0.0560	No
5	Hmox1	626	0.610	0.0534	No
6	Slc7a11	829	0.569	0.0562	No
7	H1f2	846	0.567	0.0668	No
8	Zmat3	860	0.565	0.0775	No
9	Gadd45a	1194	0.519	0.0737	No
10	Tax1bp3	1308	0.503	0.0789	No
11	Ccp110	1469	0.488	0.0818	No
12	Apaf1	1472	0.488	0.0915	No
13	Fos	1497	0.484	0.1001	No
14	Tgfa	1631	0.468	0.1038	No
15	Nudt15	1869	0.451	0.1027	No
16	Gls2	2139	0.430	0.0998	No
17	App	2153	0.428	0.1078	No
18	Tchh	2179	0.426	0.1152	No
19	Slc3a2	2205	0.423	0.1226	No
20	Nupr1	2293	0.416	0.1272	No
21	Cdkn2a	2431	0.406	0.1295	No
22	Trp63	2567	0.396	0.1316	No
23	Jun	2721	0.387	0.1328	No
24	Slc35d1	2922	0.375	0.1318	No
25	Retsat	3111	0.361	0.1310	No
26	S100a10	3141	0.359	0.1369	No
27	Zfp36l1	3271	0.351	0.1384	No
28	Lif	3343	0.346	0.1423	No
29	Pmm1	3372	0.345	0.1480	No
30	H2ac25	3419	0.341	0.1529	No
31	Ctsd	3553	0.335	0.1539	No
32	Plxnb2	3572	0.334	0.1598	No
33	Tspyl2	3583	0.333	0.1660	No
34	Sertad3	3662	0.328	0.1692	No
35	Hspa4l	4072	0.307	0.1579	No
36	Tpd52l1	4160	0.301	0.1602	No
37	Ifi30	4275	0.294	0.1612	No
38	Cd82	4307	0.293	0.1657	No
39	Perp	4396	0.289	0.1677	No
40	Klf4	4524	0.283	0.1680	No
41	Aen	4660	0.278	0.1678	No
42	Txnip	4694	0.276	0.1719	No
43	Elp1	4768	0.272	0.1742	No
44	Ier5	4956	0.262	0.1714	No
45	Rhbdf2	5003	0.260	0.1747	No
46	Polh	5142	0.252	0.1738	No
47	Foxo3	5153	0.252	0.1784	No
48	Sdc1	5203	0.248	0.1813	No
49	Trib3	5319	0.243	0.1812	No
50	Plk3	5595	0.229	0.1741	No
51	Fdxr	5910	0.219	0.1651	No
52	Abat	6102	0.209	0.1611	No
53	Itgb4	6245	0.203	0.1591	No
54	Procr	6746	0.186	0.1415	No
55	Ip6k2	6767	0.185	0.1443	No
56	Rad51c	7037	0.173	0.1363	No
57	Rnf19b	7091	0.171	0.1374	No
58	Ninj1	7148	0.169	0.1384	No
59	Acvr1b	7221	0.166	0.1386	No
60	Fas	7301	0.163	0.1385	No
61	Rap2b	7690	0.146	0.1249	No
62	Sp1	7696	0.146	0.1276	No
63	Ak1	7772	0.143	0.1272	No
64	Fbxw7	7868	0.139	0.1260	No
65	Mapkapk3	8120	0.130	0.1179	No
66	Ccng1	8230	0.125	0.1157	No
67	Bax	8240	0.125	0.1178	No
68	Rab40c	8262	0.124	0.1194	No
69	Csrnp2	8495	0.123	0.1120	No
70	Pcna	8980	0.104	0.0934	No
71	Vwa5a	9267	0.093	0.0830	No
72	Ercc5	9284	0.093	0.0842	No
73	Hras	9340	0.090	0.0837	No
74	Mknk2	9505	0.085	0.0784	No
75	Xpc	9559	0.083	0.0777	No
76	Rps27l	9614	0.081	0.0770	No
77	Fam162a	9683	0.078	0.0757	No
78	S100a4	9836	0.072	0.0707	No
79	Ddit4	9851	0.071	0.0715	No
80	Klk8	9900	0.070	0.0708	No
81	Tob1	10085	0.063	0.0642	No
82	Rxra	10332	0.055	0.0548	No
83	Casp1	10342	0.054	0.0555	No
84	Ddit3	10402	0.052	0.0541	No
85	Cdk5r1	10636	0.044	0.0450	No
86	Ier3	10737	0.041	0.0415	No
87	Sat1	10797	0.039	0.0398	No
88	Traf4	11253	0.024	0.0209	No
89	Tnni1	11545	0.013	0.0087	No
90	Ppm1d	11694	0.008	0.0025	No
91	Nol8	11705	0.008	0.0023	No
92	Pvt1	11751	0.006	0.0005	No
93	Ppp1r15a	11887	0.002	-0.0052	No
94	Cd81	11898	0.001	-0.0056	No
95	Ctsf	12109	-0.002	-0.0146	No
96	Mdm2	12265	-0.008	-0.0210	No
97	Atf3	12314	-0.010	-0.0229	No
98	Cdkn1a	12342	-0.011	-0.0238	No
99	Zfp365	12352	-0.011	-0.0240	No
100	Ddb2	12368	-0.012	-0.0244	No
101	Blcap	12699	-0.023	-0.0380	No
102	Rb1	12976	-0.033	-0.0491	No
103	Wwp1	13068	-0.036	-0.0523	No
104	Steap3	13134	-0.038	-0.0543	No
105	Prmt2	13286	-0.044	-0.0599	No
106	Fuca1	13408	-0.048	-0.0641	No
107	Tcn2	13614	-0.055	-0.0717	No
108	Ei24	13820	-0.062	-0.0792	No
109	Btg1	13869	-0.063	-0.0800	No
110	Ephx1	13970	-0.067	-0.0829	No
111	Ada	14119	-0.072	-0.0878	No
112	Cyfip2	14135	-0.072	-0.0870	No
113	Rps12	14286	-0.078	-0.0918	No
114	Tap1	14358	-0.081	-0.0933	No
115	H2aj	14515	-0.087	-0.0982	No
116	Irag2	14569	-0.089	-0.0986	No
117	Abcc5	14596	-0.090	-0.0980	No
118	Fgf13	14747	-0.095	-0.1024	No
119	Btg2	14863	-0.099	-0.1054	No
120	Ccnk	14943	-0.103	-0.1067	No
121	Dnttip2	14984	-0.104	-0.1063	No
122	Prkab1	15058	-0.107	-0.1073	No
123	Rad9a	15302	-0.117	-0.1153	No
124	Rpl36	15655	-0.129	-0.1278	No
125	Tm7sf3	15962	-0.141	-0.1380	No
126	Sesn1	15986	-0.142	-0.1362	No
127	Dram1	16022	-0.143	-0.1348	No
128	Baiap2	16064	-0.144	-0.1337	No
129	Trp53	16102	-0.145	-0.1324	No
130	Sec61a1	16130	-0.147	-0.1306	No
131	Hdac3	16223	-0.150	-0.1315	No
132	Ptpn14	16272	-0.152	-0.1305	No
133	Trafd1	16508	-0.160	-0.1374	No
134	Phlda3	16530	-0.162	-0.1350	No
135	Triap1	16745	-0.171	-0.1407	No
136	Slc19a2	16749	-0.171	-0.1375	No
137	Epha2	16796	-0.172	-0.1360	No
138	Clca2	16803	-0.173	-0.1328	No
139	Cdh13	16922	-0.178	-0.1343	No
140	Kif13b	17015	-0.181	-0.1346	No
141	Ccnd2	17240	-0.187	-0.1404	No
142	Cebpa	17422	-0.194	-0.1442	No
143	Rrad	17647	-0.203	-0.1497	No
144	Ldhb	17773	-0.207	-0.1509	No
145	Ralgds	18456	-0.236	-0.1753	No
146	Jag2	18467	-0.236	-0.1710	No
147	Bak1	18534	-0.238	-0.1691	No
148	Rpl18	18559	-0.239	-0.1653	No
149	Rack1	18638	-0.243	-0.1638	No
150	Alox8	18685	-0.245	-0.1609	No
151	Dgka	19129	-0.267	-0.1745	No
152	Rrp8	19179	-0.270	-0.1712	No
153	Ankra2	19423	-0.280	-0.1760	No
154	Rchy1	19491	-0.283	-0.1732	No
155	Sfn	19500	-0.284	-0.1678	No
156	Vdr	19970	-0.309	-0.1817	No
157	Coq8a	20193	-0.319	-0.1848	No
158	Hint1	20513	-0.337	-0.1917	No
159	Pom121	20750	-0.353	-0.1947	Yes
160	Def6	20773	-0.355	-0.1885	Yes
161	Mxd1	20975	-0.368	-0.1898	Yes
162	Ccnd3	21072	-0.374	-0.1864	Yes
163	Tgfb1	21120	-0.378	-0.1809	Yes
164	Cdkn2aip	21206	-0.384	-0.1768	Yes
165	Ndrg1	21313	-0.392	-0.1735	Yes
166	Ptpre	21355	-0.395	-0.1674	Yes
167	Dcxr	21591	-0.413	-0.1691	Yes
168	Abhd4	22000	-0.447	-0.1776	Yes
169	Pidd1	22081	-0.456	-0.1719	Yes
170	Notch1	22095	-0.457	-0.1634	Yes
171	Eps8l2	22147	-0.461	-0.1563	Yes
172	Hbegf	22162	-0.462	-0.1477	Yes
173	Gm2a	22184	-0.464	-0.1393	Yes
174	Tprkb	22270	-0.475	-0.1335	Yes
175	Wrap73	22273	-0.475	-0.1241	Yes
176	Pdgfa	22322	-0.481	-0.1165	Yes
177	Cgrrf1	22345	-0.483	-0.1078	Yes
178	Irak1	22356	-0.484	-0.0986	Yes
179	Pitpnc1	22509	-0.502	-0.0950	Yes
180	Mxd4	22739	-0.534	-0.0941	Yes
181	Iscu	22802	-0.543	-0.0859	Yes
182	Socs1	22945	-0.569	-0.0806	Yes
183	St14	23127	-0.616	-0.0760	Yes
184	Vamp8	23154	-0.622	-0.0647	Yes
185	Rgs16	23156	-0.623	-0.0523	Yes
186	Zbtb16	23243	-0.652	-0.0430	Yes
187	Tsc22d1	23287	-0.667	-0.0315	Yes
188	F2r	23363	-0.694	-0.0208	Yes
189	Tnfsf9	23435	-0.736	-0.0092	Yes
190	Sphk1	23549	-0.860	0.0032	Yes