| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group4.GMP.mono_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.44259736 |
| Normalized Enrichment Score (NES) | 1.6763594 |
| Nominal p-value | 0.047169812 |
| FDR q-value | 0.104088016 |
| FWER p-Value | 0.179 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hspa8 | 78 | 0.888 | 0.0155 | Yes |
| 2 | Srsf1 | 119 | 0.832 | 0.0315 | Yes |
| 3 | Kpnb1 | 306 | 0.721 | 0.0388 | Yes |
| 4 | Aurka | 360 | 0.696 | 0.0513 | Yes |
| 5 | Hnrnpu | 380 | 0.687 | 0.0651 | Yes |
| 6 | Plk1 | 653 | 0.603 | 0.0663 | Yes |
| 7 | Odc1 | 691 | 0.595 | 0.0773 | Yes |
| 8 | Racgap1 | 738 | 0.587 | 0.0878 | Yes |
| 9 | Hmmr | 773 | 0.581 | 0.0987 | Yes |
| 10 | Cdkn2c | 817 | 0.573 | 0.1090 | Yes |
| 11 | Incenp | 865 | 0.565 | 0.1190 | Yes |
| 12 | Upf1 | 893 | 0.562 | 0.1298 | Yes |
| 13 | Lbr | 916 | 0.559 | 0.1407 | Yes |
| 14 | Ccnf | 930 | 0.557 | 0.1520 | Yes |
| 15 | Hnrnpd | 992 | 0.547 | 0.1610 | Yes |
| 16 | Dr1 | 1028 | 0.541 | 0.1710 | Yes |
| 17 | Ccna2 | 1043 | 0.539 | 0.1818 | Yes |
| 18 | Prc1 | 1129 | 0.526 | 0.1893 | Yes |
| 19 | Kif11 | 1176 | 0.521 | 0.1984 | Yes |
| 20 | Chmp1a | 1195 | 0.518 | 0.2086 | Yes |
| 21 | Lmnb1 | 1200 | 0.518 | 0.2195 | Yes |
| 22 | Nek2 | 1238 | 0.513 | 0.2288 | Yes |
| 23 | Kif2c | 1252 | 0.512 | 0.2391 | Yes |
| 24 | Xpo1 | 1365 | 0.497 | 0.2449 | Yes |
| 25 | Espl1 | 1395 | 0.495 | 0.2541 | Yes |
| 26 | Cdc25b | 1569 | 0.475 | 0.2568 | Yes |
| 27 | Ddx39a | 1601 | 0.471 | 0.2655 | Yes |
| 28 | Smc1a | 1765 | 0.458 | 0.2683 | Yes |
| 29 | Kif23 | 1788 | 0.457 | 0.2770 | Yes |
| 30 | Cenpf | 1793 | 0.456 | 0.2865 | Yes |
| 31 | Cenpe | 1874 | 0.450 | 0.2927 | Yes |
| 32 | Top2a | 2019 | 0.440 | 0.2958 | Yes |
| 33 | Sqle | 2040 | 0.437 | 0.3043 | Yes |
| 34 | Cdkn1b | 2130 | 0.430 | 0.3096 | Yes |
| 35 | Ttk | 2184 | 0.426 | 0.3164 | Yes |
| 36 | Sfpq | 2231 | 0.422 | 0.3234 | Yes |
| 37 | Kif4 | 2296 | 0.416 | 0.3294 | Yes |
| 38 | Bcl3 | 2323 | 0.413 | 0.3371 | Yes |
| 39 | Kif22 | 2393 | 0.408 | 0.3428 | Yes |
| 40 | Tfdp1 | 2489 | 0.401 | 0.3473 | Yes |
| 41 | G3bp1 | 2614 | 0.394 | 0.3503 | Yes |
| 42 | Tpx2 | 2620 | 0.393 | 0.3585 | Yes |
| 43 | Ncl | 2650 | 0.391 | 0.3655 | Yes |
| 44 | Cdk1 | 2868 | 0.379 | 0.3643 | Yes |
| 45 | Rad21 | 2949 | 0.372 | 0.3688 | Yes |
| 46 | Odf2 | 3016 | 0.367 | 0.3738 | Yes |
| 47 | Tacc3 | 3076 | 0.364 | 0.3790 | Yes |
| 48 | Bub1 | 3219 | 0.355 | 0.3804 | Yes |
| 49 | Mki67 | 3261 | 0.352 | 0.3862 | Yes |
| 50 | Aurkb | 3522 | 0.337 | 0.3822 | Yes |
| 51 | Chaf1a | 3547 | 0.335 | 0.3883 | Yes |
| 52 | Mcm5 | 3741 | 0.324 | 0.3869 | Yes |
| 53 | Amd1 | 3819 | 0.318 | 0.3904 | Yes |
| 54 | Ndc80 | 3895 | 0.312 | 0.3938 | Yes |
| 55 | Nsd2 | 3934 | 0.310 | 0.3988 | Yes |
| 56 | Kif20b | 4110 | 0.305 | 0.3978 | Yes |
| 57 | Uck2 | 4145 | 0.302 | 0.4027 | Yes |
| 58 | Numa1 | 4152 | 0.302 | 0.4089 | Yes |
| 59 | Syncrip | 4294 | 0.293 | 0.4091 | Yes |
| 60 | Birc5 | 4440 | 0.289 | 0.4090 | Yes |
| 61 | Tent4a | 4447 | 0.289 | 0.4149 | Yes |
| 62 | Pafah1b1 | 4669 | 0.278 | 0.4114 | Yes |
| 63 | Nup98 | 4912 | 0.265 | 0.4067 | Yes |
| 64 | Cdc7 | 4927 | 0.264 | 0.4117 | Yes |
| 65 | Plk4 | 5020 | 0.259 | 0.4132 | Yes |
| 66 | Kif15 | 5034 | 0.258 | 0.4181 | Yes |
| 67 | Ilf3 | 5234 | 0.247 | 0.4149 | Yes |
| 68 | Mcm3 | 5282 | 0.245 | 0.4181 | Yes |
| 69 | E2f2 | 5370 | 0.241 | 0.4195 | Yes |
| 70 | Suv39h1 | 5390 | 0.240 | 0.4237 | Yes |
| 71 | Ccnb2 | 5438 | 0.237 | 0.4268 | Yes |
| 72 | Mybl2 | 5445 | 0.237 | 0.4315 | Yes |
| 73 | Tmpo | 5508 | 0.234 | 0.4338 | Yes |
| 74 | Smarcc1 | 5749 | 0.228 | 0.4284 | Yes |
| 75 | Lig3 | 5952 | 0.217 | 0.4244 | Yes |
| 76 | Fbxo5 | 5998 | 0.215 | 0.4271 | Yes |
| 77 | Dbf4 | 5999 | 0.215 | 0.4316 | Yes |
| 78 | Tnpo2 | 6070 | 0.211 | 0.4331 | Yes |
| 79 | Cdc6 | 6115 | 0.208 | 0.4357 | Yes |
| 80 | Cul3 | 6255 | 0.203 | 0.4340 | Yes |
| 81 | Polq | 6437 | 0.198 | 0.4305 | Yes |
| 82 | Cdc27 | 6470 | 0.196 | 0.4333 | Yes |
| 83 | Cks2 | 6498 | 0.195 | 0.4363 | Yes |
| 84 | Nusap1 | 6569 | 0.192 | 0.4374 | Yes |
| 85 | Slc7a5 | 6632 | 0.189 | 0.4387 | Yes |
| 86 | H2az1 | 6708 | 0.187 | 0.4395 | Yes |
| 87 | Traip | 6776 | 0.184 | 0.4406 | Yes |
| 88 | Mtf2 | 6820 | 0.183 | 0.4426 | Yes |
| 89 | Cenpa | 7027 | 0.174 | 0.4375 | No |
| 90 | Mcm2 | 7029 | 0.174 | 0.4411 | No |
| 91 | Gspt1 | 7260 | 0.165 | 0.4348 | No |
| 92 | Ctcf | 7342 | 0.161 | 0.4348 | No |
| 93 | Bard1 | 7379 | 0.160 | 0.4367 | No |
| 94 | Nasp | 7388 | 0.159 | 0.4397 | No |
| 95 | Egf | 7404 | 0.159 | 0.4424 | No |
| 96 | Rad54l | 7484 | 0.155 | 0.4423 | No |
| 97 | H2bc12 | 7763 | 0.143 | 0.4335 | No |
| 98 | Pbk | 7814 | 0.141 | 0.4344 | No |
| 99 | Sap30 | 7853 | 0.140 | 0.4357 | No |
| 100 | Efna5 | 7862 | 0.139 | 0.4383 | No |
| 101 | Tra2b | 7936 | 0.137 | 0.4381 | No |
| 102 | Smc2 | 7962 | 0.135 | 0.4399 | No |
| 103 | Nolc1 | 8002 | 0.134 | 0.4411 | No |
| 104 | Ccnt1 | 8145 | 0.129 | 0.4378 | No |
| 105 | Ewsr1 | 8148 | 0.129 | 0.4404 | No |
| 106 | Stil | 8245 | 0.125 | 0.4390 | No |
| 107 | Hira | 8633 | 0.117 | 0.4249 | No |
| 108 | Mad2l1 | 8646 | 0.116 | 0.4269 | No |
| 109 | Pds5b | 8660 | 0.115 | 0.4288 | No |
| 110 | Cul1 | 8704 | 0.114 | 0.4294 | No |
| 111 | Slc12a2 | 8826 | 0.109 | 0.4265 | No |
| 112 | Nup50 | 8840 | 0.109 | 0.4283 | No |
| 113 | Kif5b | 8845 | 0.109 | 0.4304 | No |
| 114 | Rad23b | 8861 | 0.108 | 0.4321 | No |
| 115 | Cul4a | 8896 | 0.107 | 0.4329 | No |
| 116 | Chek1 | 8959 | 0.105 | 0.4325 | No |
| 117 | Slc38a1 | 9091 | 0.100 | 0.4290 | No |
| 118 | Notch2 | 9096 | 0.099 | 0.4309 | No |
| 119 | Prpf4b | 9356 | 0.090 | 0.4218 | No |
| 120 | Pole | 9383 | 0.089 | 0.4226 | No |
| 121 | Katna1 | 9452 | 0.087 | 0.4215 | No |
| 122 | Hif1a | 9475 | 0.086 | 0.4224 | No |
| 123 | Map3k20 | 9543 | 0.083 | 0.4213 | No |
| 124 | Srsf10 | 9567 | 0.083 | 0.4221 | No |
| 125 | Mcm6 | 9705 | 0.077 | 0.4179 | No |
| 126 | Tle3 | 9790 | 0.074 | 0.4158 | No |
| 127 | Ythdc1 | 9816 | 0.073 | 0.4163 | No |
| 128 | Mapk14 | 9997 | 0.067 | 0.4101 | No |
| 129 | Knl1 | 10220 | 0.058 | 0.4018 | No |
| 130 | Smc4 | 10379 | 0.053 | 0.3962 | No |
| 131 | Hmga1b | 10414 | 0.052 | 0.3958 | No |
| 132 | Jpt1 | 10421 | 0.051 | 0.3967 | No |
| 133 | Fancc | 10472 | 0.050 | 0.3956 | No |
| 134 | Meis2 | 10483 | 0.049 | 0.3962 | No |
| 135 | Orc5 | 10618 | 0.045 | 0.3915 | No |
| 136 | Rbl1 | 10629 | 0.045 | 0.3920 | No |
| 137 | E2f3 | 10653 | 0.044 | 0.3919 | No |
| 138 | Snrpd1 | 10678 | 0.043 | 0.3918 | No |
| 139 | Top1 | 10889 | 0.036 | 0.3836 | No |
| 140 | Ss18 | 10997 | 0.032 | 0.3797 | No |
| 141 | Prmt5 | 11179 | 0.026 | 0.3725 | No |
| 142 | Cbx1 | 11340 | 0.020 | 0.3662 | No |
| 143 | Atrx | 11465 | 0.016 | 0.3612 | No |
| 144 | Wrn | 11699 | 0.008 | 0.3514 | No |
| 145 | Cdc25a | 11774 | 0.005 | 0.3484 | No |
| 146 | Cdc20 | 11902 | 0.001 | 0.3430 | No |
| 147 | Arid4a | 12053 | -0.000 | 0.3366 | No |
| 148 | Ccnd1 | 12071 | -0.001 | 0.3359 | No |
| 149 | Kmt5a | 12136 | -0.003 | 0.3332 | No |
| 150 | Abl1 | 12163 | -0.004 | 0.3322 | No |
| 151 | Ube2s | 12202 | -0.006 | 0.3307 | No |
| 152 | Dtymk | 12227 | -0.006 | 0.3298 | No |
| 153 | Atf5 | 12261 | -0.008 | 0.3286 | No |
| 154 | Cul5 | 12422 | -0.014 | 0.3220 | No |
| 155 | Casp8ap2 | 12474 | -0.016 | 0.3202 | No |
| 156 | Mnat1 | 12478 | -0.016 | 0.3204 | No |
| 157 | Stmn1 | 12581 | -0.019 | 0.3164 | No |
| 158 | Dkc1 | 12690 | -0.023 | 0.3123 | No |
| 159 | Stag1 | 12718 | -0.023 | 0.3117 | No |
| 160 | Srsf2 | 12894 | -0.030 | 0.3048 | No |
| 161 | Slc7a1 | 12903 | -0.030 | 0.3051 | No |
| 162 | Exo1 | 12986 | -0.033 | 0.3023 | No |
| 163 | Prim2 | 13226 | -0.042 | 0.2930 | No |
| 164 | Pola2 | 13365 | -0.047 | 0.2881 | No |
| 165 | Pttg1 | 13943 | -0.066 | 0.2649 | No |
| 166 | Cdk4 | 13966 | -0.067 | 0.2654 | No |
| 167 | Rasal2 | 14447 | -0.085 | 0.2467 | No |
| 168 | Troap | 14478 | -0.086 | 0.2472 | No |
| 169 | Ezh2 | 14561 | -0.089 | 0.2456 | No |
| 170 | E2f4 | 14743 | -0.095 | 0.2399 | No |
| 171 | Meis1 | 14946 | -0.103 | 0.2335 | No |
| 172 | Smad3 | 15543 | -0.126 | 0.2107 | No |
| 173 | Ube2c | 15692 | -0.130 | 0.2072 | No |
| 174 | Orc6 | 16821 | -0.173 | 0.1627 | No |
| 175 | Cdc45 | 17193 | -0.186 | 0.1508 | No |
| 176 | Rps6ka5 | 17205 | -0.186 | 0.1543 | No |
| 177 | Hus1 | 17253 | -0.188 | 0.1563 | No |
| 178 | Hmgb3 | 17430 | -0.195 | 0.1529 | No |
| 179 | Cks1b | 17582 | -0.200 | 0.1507 | No |
| 180 | Bub3 | 18168 | -0.222 | 0.1304 | No |
| 181 | Foxn3 | 18220 | -0.225 | 0.1330 | No |
| 182 | H2ax | 18546 | -0.238 | 0.1242 | No |
| 183 | Brca2 | 18709 | -0.246 | 0.1225 | No |
| 184 | Rpa2 | 18794 | -0.250 | 0.1243 | No |
| 185 | Cdkn3 | 20112 | -0.313 | 0.0747 | No |
| 186 | E2f1 | 20169 | -0.317 | 0.0790 | No |
| 187 | Dmd | 20525 | -0.338 | 0.0710 | No |
| 188 | Pura | 20644 | -0.346 | 0.0733 | No |
| 189 | Pml | 20661 | -0.347 | 0.0800 | No |
| 190 | Tgfb1 | 21120 | -0.378 | 0.0685 | No |
| 191 | H2az2 | 21263 | -0.389 | 0.0707 | No |
| 192 | Myc | 21678 | -0.422 | 0.0620 | No |
| 193 | Marcks | 22452 | -0.494 | 0.0395 | No |
| 194 | Gins2 | 22468 | -0.496 | 0.0493 | No |

