| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group4.GMP.mono_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.4123381 |
| Normalized Enrichment Score (NES) | 1.5172204 |
| Nominal p-value | 0.13846155 |
| FDR q-value | 0.20037809 |
| FWER p-Value | 0.396 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Srsf1 | 119 | 0.832 | 0.0125 | Yes |
| 2 | Dck | 160 | 0.795 | 0.0276 | Yes |
| 3 | Aurka | 360 | 0.696 | 0.0338 | Yes |
| 4 | Ccne1 | 365 | 0.693 | 0.0483 | Yes |
| 5 | Ipo7 | 412 | 0.677 | 0.0606 | Yes |
| 6 | Ncapd2 | 599 | 0.615 | 0.0657 | Yes |
| 7 | Plk1 | 653 | 0.603 | 0.0762 | Yes |
| 8 | Racgap1 | 738 | 0.587 | 0.0850 | Yes |
| 9 | Hmmr | 773 | 0.581 | 0.0958 | Yes |
| 10 | Cdkn2c | 817 | 0.573 | 0.1061 | Yes |
| 11 | Dlgap5 | 831 | 0.569 | 0.1176 | Yes |
| 12 | Lbr | 916 | 0.559 | 0.1258 | Yes |
| 13 | Rrm2 | 988 | 0.548 | 0.1343 | Yes |
| 14 | Hnrnpd | 992 | 0.547 | 0.1458 | Yes |
| 15 | Prps1 | 1116 | 0.527 | 0.1517 | Yes |
| 16 | Lmnb1 | 1200 | 0.518 | 0.1591 | Yes |
| 17 | Kif2c | 1252 | 0.512 | 0.1677 | Yes |
| 18 | Ssrp1 | 1321 | 0.502 | 0.1754 | Yes |
| 19 | Xpo1 | 1365 | 0.497 | 0.1841 | Yes |
| 20 | Espl1 | 1395 | 0.495 | 0.1933 | Yes |
| 21 | Rbbp7 | 1429 | 0.493 | 0.2023 | Yes |
| 22 | Ccp110 | 1469 | 0.488 | 0.2110 | Yes |
| 23 | Dnmt1 | 1559 | 0.477 | 0.2173 | Yes |
| 24 | Cdc25b | 1569 | 0.475 | 0.2269 | Yes |
| 25 | Ddx39a | 1601 | 0.471 | 0.2356 | Yes |
| 26 | Cdca8 | 1610 | 0.470 | 0.2451 | Yes |
| 27 | Smc1a | 1765 | 0.458 | 0.2483 | Yes |
| 28 | Cenpe | 1874 | 0.450 | 0.2532 | Yes |
| 29 | Bub1b | 1893 | 0.448 | 0.2619 | Yes |
| 30 | Top2a | 2019 | 0.440 | 0.2658 | Yes |
| 31 | Mthfd2 | 2045 | 0.437 | 0.2740 | Yes |
| 32 | Cdkn1b | 2130 | 0.430 | 0.2795 | Yes |
| 33 | Mcm4 | 2155 | 0.428 | 0.2875 | Yes |
| 34 | Kif4 | 2296 | 0.416 | 0.2904 | Yes |
| 35 | Kif22 | 2393 | 0.408 | 0.2949 | Yes |
| 36 | Spc25 | 2429 | 0.406 | 0.3020 | Yes |
| 37 | Cdkn2a | 2431 | 0.406 | 0.3105 | Yes |
| 38 | Slbp | 2468 | 0.402 | 0.3175 | Yes |
| 39 | Ubr7 | 2546 | 0.398 | 0.3226 | Yes |
| 40 | Kif18b | 2617 | 0.394 | 0.3279 | Yes |
| 41 | Cse1l | 2712 | 0.387 | 0.3321 | Yes |
| 42 | Smc3 | 2842 | 0.381 | 0.3347 | Yes |
| 43 | Cdk1 | 2868 | 0.379 | 0.3416 | Yes |
| 44 | Rad21 | 2949 | 0.372 | 0.3460 | Yes |
| 45 | Spag5 | 2989 | 0.368 | 0.3522 | Yes |
| 46 | Tacc3 | 3076 | 0.364 | 0.3562 | Yes |
| 47 | Mki67 | 3261 | 0.352 | 0.3558 | Yes |
| 48 | Nap1l1 | 3434 | 0.341 | 0.3556 | Yes |
| 49 | Nup107 | 3477 | 0.339 | 0.3610 | Yes |
| 50 | Shmt1 | 3511 | 0.337 | 0.3667 | Yes |
| 51 | Aurkb | 3522 | 0.337 | 0.3734 | Yes |
| 52 | Anp32e | 3644 | 0.329 | 0.3752 | Yes |
| 53 | Mcm5 | 3741 | 0.324 | 0.3780 | Yes |
| 54 | Tfrc | 3855 | 0.315 | 0.3798 | Yes |
| 55 | Ak2 | 3917 | 0.311 | 0.3838 | Yes |
| 56 | Pan2 | 3967 | 0.309 | 0.3882 | Yes |
| 57 | Cbx5 | 4276 | 0.294 | 0.3813 | Yes |
| 58 | Nup205 | 4277 | 0.294 | 0.3875 | Yes |
| 59 | Syncrip | 4294 | 0.293 | 0.3930 | Yes |
| 60 | Birc5 | 4440 | 0.289 | 0.3929 | Yes |
| 61 | Cit | 4493 | 0.285 | 0.3968 | Yes |
| 62 | Ranbp1 | 4720 | 0.274 | 0.3929 | Yes |
| 63 | Tubb5 | 4734 | 0.274 | 0.3981 | Yes |
| 64 | Ppp1r8 | 4982 | 0.261 | 0.3931 | Yes |
| 65 | Plk4 | 5020 | 0.259 | 0.3970 | Yes |
| 66 | Brca1 | 5039 | 0.257 | 0.4017 | Yes |
| 67 | Ilf3 | 5234 | 0.247 | 0.3986 | Yes |
| 68 | Mcm3 | 5282 | 0.245 | 0.4018 | Yes |
| 69 | Suv39h1 | 5390 | 0.240 | 0.4023 | Yes |
| 70 | Ccnb2 | 5438 | 0.237 | 0.4053 | Yes |
| 71 | Mybl2 | 5445 | 0.237 | 0.4100 | Yes |
| 72 | Tmpo | 5508 | 0.234 | 0.4123 | Yes |
| 73 | Lsm8 | 5762 | 0.227 | 0.4063 | No |
| 74 | Msh2 | 5859 | 0.222 | 0.4069 | No |
| 75 | Tcf19 | 6038 | 0.213 | 0.4038 | No |
| 76 | Zw10 | 6118 | 0.208 | 0.4049 | No |
| 77 | Cks2 | 6498 | 0.195 | 0.3928 | No |
| 78 | Atad2 | 6575 | 0.191 | 0.3936 | No |
| 79 | Lyar | 6666 | 0.189 | 0.3937 | No |
| 80 | H2az1 | 6708 | 0.187 | 0.3959 | No |
| 81 | Mcm7 | 6810 | 0.183 | 0.3955 | No |
| 82 | Rpa3 | 6851 | 0.181 | 0.3976 | No |
| 83 | Hmgb2 | 6914 | 0.179 | 0.3988 | No |
| 84 | Mcm2 | 7029 | 0.174 | 0.3976 | No |
| 85 | Rad51c | 7037 | 0.173 | 0.4009 | No |
| 86 | E2f8 | 7235 | 0.166 | 0.3960 | No |
| 87 | Gspt1 | 7260 | 0.165 | 0.3985 | No |
| 88 | Nop56 | 7307 | 0.163 | 0.4000 | No |
| 89 | Ctcf | 7342 | 0.161 | 0.4019 | No |
| 90 | Eif2s1 | 7353 | 0.161 | 0.4049 | No |
| 91 | Bard1 | 7379 | 0.160 | 0.4072 | No |
| 92 | Nasp | 7388 | 0.159 | 0.4102 | No |
| 93 | Tbrg4 | 7556 | 0.152 | 0.4063 | No |
| 94 | Hells | 7621 | 0.149 | 0.4068 | No |
| 95 | Xrcc6 | 7921 | 0.137 | 0.3969 | No |
| 96 | Tra2b | 7936 | 0.137 | 0.3992 | No |
| 97 | Ing3 | 7968 | 0.135 | 0.4007 | No |
| 98 | Nolc1 | 8002 | 0.134 | 0.4021 | No |
| 99 | Melk | 8105 | 0.130 | 0.4005 | No |
| 100 | Paics | 8175 | 0.127 | 0.4003 | No |
| 101 | Psip1 | 8640 | 0.116 | 0.3829 | No |
| 102 | Mad2l1 | 8646 | 0.116 | 0.3852 | No |
| 103 | Pds5b | 8660 | 0.115 | 0.3871 | No |
| 104 | Chek1 | 8959 | 0.105 | 0.3766 | No |
| 105 | Depdc1a | 8973 | 0.104 | 0.3782 | No |
| 106 | Pcna | 8980 | 0.104 | 0.3801 | No |
| 107 | Rfc1 | 8981 | 0.104 | 0.3823 | No |
| 108 | Mre11a | 9043 | 0.102 | 0.3819 | No |
| 109 | Pnn | 9117 | 0.099 | 0.3808 | No |
| 110 | Phf5a | 9281 | 0.093 | 0.3758 | No |
| 111 | Chek2 | 9334 | 0.091 | 0.3755 | No |
| 112 | Pole | 9383 | 0.089 | 0.3754 | No |
| 113 | Eed | 9458 | 0.086 | 0.3740 | No |
| 114 | Mcm6 | 9705 | 0.077 | 0.3652 | No |
| 115 | Lig1 | 9720 | 0.076 | 0.3662 | No |
| 116 | Timeless | 9727 | 0.076 | 0.3675 | No |
| 117 | Wee1 | 9934 | 0.069 | 0.3602 | No |
| 118 | Prkdc | 10029 | 0.065 | 0.3576 | No |
| 119 | Pole4 | 10152 | 0.061 | 0.3537 | No |
| 120 | Smc4 | 10379 | 0.053 | 0.3451 | No |
| 121 | Diaph3 | 10403 | 0.052 | 0.3452 | No |
| 122 | Hmga1b | 10414 | 0.052 | 0.3459 | No |
| 123 | Jpt1 | 10421 | 0.051 | 0.3467 | No |
| 124 | Pa2g4 | 11300 | 0.022 | 0.3097 | No |
| 125 | Gins4 | 11482 | 0.015 | 0.3023 | No |
| 126 | Ppm1d | 11694 | 0.008 | 0.2935 | No |
| 127 | Usp1 | 11757 | 0.006 | 0.2910 | No |
| 128 | Cdc25a | 11774 | 0.005 | 0.2904 | No |
| 129 | Nup153 | 11895 | 0.002 | 0.2853 | No |
| 130 | Cdc20 | 11902 | 0.001 | 0.2851 | No |
| 131 | Dut | 11928 | 0.001 | 0.2840 | No |
| 132 | Tk1 | 12090 | -0.001 | 0.2772 | No |
| 133 | Cdca3 | 12173 | -0.004 | 0.2738 | No |
| 134 | Ube2s | 12202 | -0.006 | 0.2727 | No |
| 135 | Cdkn1a | 12342 | -0.011 | 0.2670 | No |
| 136 | Psmc3ip | 12570 | -0.019 | 0.2577 | No |
| 137 | Mlh1 | 12579 | -0.019 | 0.2578 | No |
| 138 | Stmn1 | 12581 | -0.019 | 0.2582 | No |
| 139 | Rad51ap1 | 12649 | -0.021 | 0.2557 | No |
| 140 | Stag1 | 12718 | -0.023 | 0.2533 | No |
| 141 | Orc2 | 12721 | -0.023 | 0.2537 | No |
| 142 | Nbn | 12768 | -0.025 | 0.2523 | No |
| 143 | Smc6 | 12776 | -0.025 | 0.2525 | No |
| 144 | Srsf2 | 12894 | -0.030 | 0.2482 | No |
| 145 | Ran | 13106 | -0.037 | 0.2399 | No |
| 146 | Prim2 | 13226 | -0.042 | 0.2357 | No |
| 147 | Snrpb | 13249 | -0.043 | 0.2357 | No |
| 148 | Ung | 13348 | -0.046 | 0.2325 | No |
| 149 | Pola2 | 13365 | -0.047 | 0.2328 | No |
| 150 | Pttg1 | 13943 | -0.066 | 0.2096 | No |
| 151 | Cdk4 | 13966 | -0.067 | 0.2101 | No |
| 152 | Dek | 14129 | -0.072 | 0.2047 | No |
| 153 | Rad1 | 14302 | -0.079 | 0.1990 | No |
| 154 | Rpa1 | 14352 | -0.081 | 0.1986 | No |
| 155 | Rad50 | 14506 | -0.087 | 0.1939 | No |
| 156 | Ezh2 | 14561 | -0.089 | 0.1935 | No |
| 157 | Trip13 | 14588 | -0.090 | 0.1943 | No |
| 158 | Spc24 | 14826 | -0.098 | 0.1863 | No |
| 159 | Gins3 | 15048 | -0.106 | 0.1791 | No |
| 160 | Tipin | 15068 | -0.107 | 0.1805 | No |
| 161 | Pold3 | 15198 | -0.112 | 0.1774 | No |
| 162 | Nme1 | 15267 | -0.115 | 0.1769 | No |
| 163 | Brms1l | 15309 | -0.117 | 0.1776 | No |
| 164 | Exosc8 | 15398 | -0.120 | 0.1764 | No |
| 165 | Donson | 15508 | -0.124 | 0.1744 | No |
| 166 | Rfc3 | 15598 | -0.128 | 0.1733 | No |
| 167 | Mms22l | 15780 | -0.134 | 0.1684 | No |
| 168 | Trp53 | 16102 | -0.145 | 0.1578 | No |
| 169 | Pold2 | 16264 | -0.152 | 0.1541 | No |
| 170 | Gins1 | 16266 | -0.152 | 0.1573 | No |
| 171 | Dctpp1 | 16481 | -0.159 | 0.1515 | No |
| 172 | Tubg1 | 16717 | -0.170 | 0.1450 | No |
| 173 | Cnot9 | 16720 | -0.170 | 0.1485 | No |
| 174 | Pms2 | 16743 | -0.171 | 0.1512 | No |
| 175 | Nudt21 | 16781 | -0.172 | 0.1533 | No |
| 176 | Orc6 | 16821 | -0.173 | 0.1553 | No |
| 177 | Luc7l3 | 16910 | -0.177 | 0.1553 | No |
| 178 | Pold1 | 17079 | -0.184 | 0.1520 | No |
| 179 | Hus1 | 17253 | -0.188 | 0.1486 | No |
| 180 | Rnaseh2a | 17341 | -0.191 | 0.1489 | No |
| 181 | Hmgb3 | 17430 | -0.195 | 0.1492 | No |
| 182 | Pop7 | 17491 | -0.197 | 0.1508 | No |
| 183 | Cks1b | 17582 | -0.200 | 0.1512 | No |
| 184 | Ube2t | 17627 | -0.202 | 0.1536 | No |
| 185 | Asf1b | 18255 | -0.227 | 0.1317 | No |
| 186 | H2ax | 18546 | -0.238 | 0.1243 | No |
| 187 | Brca2 | 18709 | -0.246 | 0.1226 | No |
| 188 | Rpa2 | 18794 | -0.250 | 0.1243 | No |
| 189 | Dclre1b | 18989 | -0.259 | 0.1215 | No |
| 190 | Wdr90 | 19063 | -0.264 | 0.1240 | No |
| 191 | Cdkn3 | 20112 | -0.313 | 0.0858 | No |
| 192 | Asf1a | 20145 | -0.315 | 0.0911 | No |
| 193 | Cenpm | 21173 | -0.381 | 0.0554 | No |
| 194 | Mxd3 | 21605 | -0.415 | 0.0457 | No |
| 195 | Myc | 21678 | -0.422 | 0.0516 | No |
| 196 | Rfc2 | 22173 | -0.463 | 0.0403 | No |
| 197 | Dscc1 | 22474 | -0.497 | 0.0380 | No |
| 198 | Prdx4 | 22675 | -0.524 | 0.0405 | No |

