| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group4.GMP.mono_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_APICAL_JUNCTION |
| Enrichment Score (ES) | -0.15763989 |
| Normalized Enrichment Score (NES) | -0.6850196 |
| Nominal p-value | 0.97352344 |
| FDR q-value | 0.9422106 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdk8 | 124 | 0.829 | 0.0142 | No |
| 2 | Cd86 | 157 | 0.802 | 0.0317 | No |
| 3 | Dhx16 | 568 | 0.627 | 0.0290 | No |
| 4 | Myh9 | 727 | 0.590 | 0.0362 | No |
| 5 | Mpzl1 | 788 | 0.578 | 0.0472 | No |
| 6 | Tmem8b | 1174 | 0.522 | 0.0430 | No |
| 7 | Adam9 | 1263 | 0.511 | 0.0513 | No |
| 8 | Ywhah | 1304 | 0.504 | 0.0615 | No |
| 9 | Gnai1 | 1413 | 0.494 | 0.0685 | No |
| 10 | Inppl1 | 1501 | 0.484 | 0.0762 | No |
| 11 | Mmp9 | 1680 | 0.463 | 0.0795 | No |
| 12 | Cadm3 | 1804 | 0.455 | 0.0849 | No |
| 13 | Flnc | 2129 | 0.430 | 0.0812 | No |
| 14 | Jam3 | 2225 | 0.422 | 0.0871 | No |
| 15 | Adam15 | 2618 | 0.394 | 0.0797 | No |
| 16 | Cd276 | 2952 | 0.372 | 0.0742 | No |
| 17 | Itgb1 | 3266 | 0.352 | 0.0691 | No |
| 18 | Fscn1 | 3568 | 0.334 | 0.0642 | No |
| 19 | Actn3 | 3637 | 0.330 | 0.0690 | No |
| 20 | Cdh4 | 3699 | 0.327 | 0.0741 | No |
| 21 | Msn | 3712 | 0.326 | 0.0813 | No |
| 22 | Epb41l2 | 4016 | 0.308 | 0.0756 | No |
| 23 | Tro | 4019 | 0.308 | 0.0828 | No |
| 24 | Myh10 | 4267 | 0.295 | 0.0792 | No |
| 25 | Ikbkg | 4268 | 0.295 | 0.0861 | No |
| 26 | Gtf2f1 | 4339 | 0.291 | 0.0900 | No |
| 27 | Rras | 4350 | 0.290 | 0.0964 | No |
| 28 | Parva | 4390 | 0.290 | 0.1015 | No |
| 29 | Vwf | 4702 | 0.276 | 0.0947 | No |
| 30 | Tsc1 | 4782 | 0.271 | 0.0977 | No |
| 31 | Plcg1 | 5065 | 0.256 | 0.0917 | No |
| 32 | Vcl | 5199 | 0.249 | 0.0919 | No |
| 33 | Actg2 | 5307 | 0.244 | 0.0931 | No |
| 34 | Lima1 | 5437 | 0.237 | 0.0932 | No |
| 35 | Rasa1 | 5459 | 0.236 | 0.0978 | No |
| 36 | Insig1 | 5544 | 0.231 | 0.0997 | No |
| 37 | Ctnna1 | 5584 | 0.230 | 0.1034 | No |
| 38 | Crat | 5592 | 0.230 | 0.1086 | No |
| 39 | Actb | 5831 | 0.223 | 0.1037 | No |
| 40 | Itga3 | 5951 | 0.217 | 0.1037 | No |
| 41 | Itga2 | 6078 | 0.211 | 0.1033 | No |
| 42 | Thbs3 | 6199 | 0.205 | 0.1030 | No |
| 43 | Actg1 | 6202 | 0.205 | 0.1077 | No |
| 44 | Itgb4 | 6245 | 0.203 | 0.1107 | No |
| 45 | Nrtn | 6445 | 0.197 | 0.1069 | No |
| 46 | Arhgef6 | 6533 | 0.193 | 0.1077 | No |
| 47 | Nrap | 6589 | 0.191 | 0.1099 | No |
| 48 | Icam1 | 6769 | 0.185 | 0.1066 | No |
| 49 | Amh | 6890 | 0.180 | 0.1057 | No |
| 50 | Wasl | 6916 | 0.179 | 0.1088 | No |
| 51 | Shroom2 | 6937 | 0.177 | 0.1121 | No |
| 52 | Actn2 | 6974 | 0.176 | 0.1148 | No |
| 53 | Pten | 6998 | 0.175 | 0.1179 | No |
| 54 | Negr1 | 7106 | 0.170 | 0.1173 | No |
| 55 | Lama3 | 7282 | 0.164 | 0.1137 | No |
| 56 | Cap1 | 7411 | 0.158 | 0.1120 | No |
| 57 | Actn1 | 7420 | 0.158 | 0.1154 | No |
| 58 | Skap2 | 7514 | 0.154 | 0.1150 | No |
| 59 | Akt2 | 7589 | 0.151 | 0.1154 | No |
| 60 | B4galt1 | 7590 | 0.150 | 0.1189 | No |
| 61 | Slc30a3 | 8017 | 0.133 | 0.1039 | No |
| 62 | Slit2 | 8033 | 0.133 | 0.1064 | No |
| 63 | Nlgn2 | 8234 | 0.125 | 0.1008 | No |
| 64 | Nf2 | 8236 | 0.125 | 0.1037 | No |
| 65 | Ptprc | 8254 | 0.125 | 0.1059 | No |
| 66 | Col9a1 | 8276 | 0.124 | 0.1080 | No |
| 67 | Dsc1 | 8291 | 0.124 | 0.1103 | No |
| 68 | Myl9 | 8300 | 0.124 | 0.1128 | No |
| 69 | Cdh3 | 8407 | 0.123 | 0.1112 | No |
| 70 | Nectin2 | 8626 | 0.117 | 0.1047 | No |
| 71 | Shc1 | 8736 | 0.113 | 0.1027 | No |
| 72 | Egfr | 8793 | 0.111 | 0.1029 | No |
| 73 | Pik3cb | 8830 | 0.109 | 0.1039 | No |
| 74 | Cntn1 | 8864 | 0.108 | 0.1051 | No |
| 75 | Cldn15 | 8881 | 0.108 | 0.1069 | No |
| 76 | Pals1 | 9108 | 0.099 | 0.0996 | No |
| 77 | Hras | 9340 | 0.090 | 0.0919 | No |
| 78 | Tial1 | 9343 | 0.090 | 0.0939 | No |
| 79 | Ctnnd1 | 9391 | 0.089 | 0.0940 | No |
| 80 | Rhof | 9412 | 0.088 | 0.0952 | No |
| 81 | Vasp | 9421 | 0.088 | 0.0970 | No |
| 82 | Map3k20 | 9543 | 0.083 | 0.0938 | No |
| 83 | Nfasc | 9605 | 0.081 | 0.0931 | No |
| 84 | Actn4 | 9781 | 0.074 | 0.0874 | No |
| 85 | Tgfbi | 9871 | 0.071 | 0.0852 | No |
| 86 | Tspan4 | 9874 | 0.071 | 0.0868 | No |
| 87 | Kcnh2 | 9946 | 0.068 | 0.0854 | No |
| 88 | Mapk14 | 9997 | 0.067 | 0.0848 | No |
| 89 | Vcan | 10437 | 0.051 | 0.0673 | No |
| 90 | Adamts5 | 10556 | 0.048 | 0.0634 | No |
| 91 | Ldlrap1 | 10690 | 0.042 | 0.0587 | No |
| 92 | Amigo2 | 10863 | 0.036 | 0.0522 | No |
| 93 | Stx4a | 11017 | 0.031 | 0.0464 | No |
| 94 | Cdh6 | 11159 | 0.027 | 0.0411 | No |
| 95 | Thy1 | 11304 | 0.022 | 0.0354 | No |
| 96 | Cdh11 | 11397 | 0.019 | 0.0320 | No |
| 97 | Mapk11 | 11631 | 0.010 | 0.0223 | No |
| 98 | Gamt | 12337 | -0.011 | -0.0076 | No |
| 99 | Mmp2 | 12338 | -0.011 | -0.0073 | No |
| 100 | Evl | 12525 | -0.017 | -0.0148 | No |
| 101 | Taok2 | 12787 | -0.026 | -0.0254 | No |
| 102 | Nrxn2 | 12913 | -0.030 | -0.0300 | No |
| 103 | Gnai2 | 12935 | -0.031 | -0.0301 | No |
| 104 | Cdh8 | 13329 | -0.045 | -0.0458 | No |
| 105 | Dlg1 | 13504 | -0.051 | -0.0520 | No |
| 106 | Speg | 13640 | -0.056 | -0.0565 | No |
| 107 | Nf1 | 13860 | -0.063 | -0.0643 | No |
| 108 | Tjp1 | 14117 | -0.072 | -0.0736 | No |
| 109 | Mvd | 14252 | -0.077 | -0.0775 | No |
| 110 | Adam23 | 14418 | -0.083 | -0.0826 | No |
| 111 | Sgce | 14491 | -0.087 | -0.0836 | No |
| 112 | Src | 14624 | -0.091 | -0.0871 | No |
| 113 | Wnk4 | 14710 | -0.094 | -0.0885 | No |
| 114 | Vcam1 | 14734 | -0.095 | -0.0872 | No |
| 115 | Irs1 | 14907 | -0.101 | -0.0922 | No |
| 116 | Vav2 | 15136 | -0.110 | -0.0993 | No |
| 117 | Mapk13 | 15483 | -0.124 | -0.1112 | No |
| 118 | Icam4 | 15489 | -0.124 | -0.1085 | No |
| 119 | Pik3r3 | 15730 | -0.132 | -0.1156 | No |
| 120 | Map4k2 | 15777 | -0.134 | -0.1144 | No |
| 121 | Lamc2 | 16020 | -0.143 | -0.1214 | No |
| 122 | Baiap2 | 16064 | -0.144 | -0.1198 | No |
| 123 | Cldn14 | 16152 | -0.147 | -0.1200 | No |
| 124 | Cadm2 | 16210 | -0.150 | -0.1189 | No |
| 125 | Icam2 | 16247 | -0.151 | -0.1169 | No |
| 126 | Zyx | 16345 | -0.154 | -0.1174 | No |
| 127 | Sirpa | 16348 | -0.154 | -0.1139 | No |
| 128 | Tubg1 | 16717 | -0.170 | -0.1256 | No |
| 129 | Adra1b | 16818 | -0.173 | -0.1258 | No |
| 130 | Syk | 16862 | -0.175 | -0.1235 | No |
| 131 | Rsu1 | 17009 | -0.181 | -0.1255 | No |
| 132 | Itga10 | 17125 | -0.185 | -0.1260 | No |
| 133 | Pkd1 | 17518 | -0.198 | -0.1381 | No |
| 134 | Hadh | 17548 | -0.199 | -0.1346 | No |
| 135 | Exoc4 | 17567 | -0.200 | -0.1307 | No |
| 136 | Lamb3 | 18034 | -0.218 | -0.1454 | No |
| 137 | Cdh1 | 18118 | -0.221 | -0.1438 | No |
| 138 | Icam5 | 18175 | -0.223 | -0.1409 | No |
| 139 | Pecam1 | 18297 | -0.229 | -0.1407 | No |
| 140 | Arpc2 | 18580 | -0.240 | -0.1471 | No |
| 141 | Alox8 | 18685 | -0.245 | -0.1458 | No |
| 142 | Nectin1 | 18828 | -0.252 | -0.1459 | No |
| 143 | Akt3 | 18964 | -0.257 | -0.1456 | No |
| 144 | Sympk | 19038 | -0.263 | -0.1425 | No |
| 145 | Mdk | 19350 | -0.278 | -0.1492 | No |
| 146 | Calb2 | 19520 | -0.285 | -0.1498 | No |
| 147 | Cx3cl1 | 19706 | -0.294 | -0.1507 | Yes |
| 148 | Jup | 19735 | -0.297 | -0.1449 | Yes |
| 149 | Crb3 | 19941 | -0.309 | -0.1464 | Yes |
| 150 | Fbn1 | 20155 | -0.316 | -0.1481 | Yes |
| 151 | Nlgn3 | 20222 | -0.320 | -0.1433 | Yes |
| 152 | Cercam | 20309 | -0.325 | -0.1394 | Yes |
| 153 | Nectin4 | 20408 | -0.330 | -0.1358 | Yes |
| 154 | Traf1 | 20463 | -0.334 | -0.1302 | Yes |
| 155 | Pfn1 | 20629 | -0.345 | -0.1291 | Yes |
| 156 | Amigo1 | 20724 | -0.352 | -0.1249 | Yes |
| 157 | Myl12b | 21025 | -0.372 | -0.1289 | Yes |
| 158 | Pbx2 | 21098 | -0.376 | -0.1231 | Yes |
| 159 | Itga9 | 21227 | -0.386 | -0.1195 | Yes |
| 160 | Cnn2 | 21329 | -0.393 | -0.1146 | Yes |
| 161 | Nectin3 | 21576 | -0.412 | -0.1154 | Yes |
| 162 | Layn | 21583 | -0.413 | -0.1059 | Yes |
| 163 | Dsc3 | 22178 | -0.463 | -0.1203 | Yes |
| 164 | Cd34 | 22576 | -0.510 | -0.1253 | Yes |
| 165 | Ptk2 | 22661 | -0.521 | -0.1166 | Yes |
| 166 | Pard6g | 22758 | -0.538 | -0.1080 | Yes |
| 167 | Nexn | 22762 | -0.539 | -0.0954 | Yes |
| 168 | Acta1 | 22796 | -0.543 | -0.0841 | Yes |
| 169 | Col17a1 | 22844 | -0.550 | -0.0731 | Yes |
| 170 | Col16a1 | 22850 | -0.551 | -0.0604 | Yes |
| 171 | Sdc3 | 22996 | -0.585 | -0.0528 | Yes |
| 172 | Cd274 | 23061 | -0.600 | -0.0414 | Yes |
| 173 | Bmp1 | 23196 | -0.637 | -0.0321 | Yes |
| 174 | Sorbs3 | 23215 | -0.642 | -0.0178 | Yes |
| 175 | Atp1a3 | 23263 | -0.657 | -0.0043 | Yes |
| 176 | Rac2 | 23539 | -0.835 | 0.0036 | Yes |

