| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group4.GMP.mono_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_ALLOGRAFT_REJECTION |
| Enrichment Score (ES) | -0.18265344 |
| Normalized Enrichment Score (NES) | -0.747777 |
| Nominal p-value | 0.84188914 |
| FDR q-value | 0.92920166 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Stab1 | 75 | 0.894 | 0.0177 | No |
| 2 | Cd86 | 157 | 0.802 | 0.0330 | No |
| 3 | Akt1 | 368 | 0.690 | 0.0401 | No |
| 4 | Itk | 497 | 0.652 | 0.0499 | No |
| 5 | Eif3a | 795 | 0.576 | 0.0507 | No |
| 6 | Trat1 | 813 | 0.573 | 0.0633 | No |
| 7 | Capg | 830 | 0.569 | 0.0759 | No |
| 8 | Il18rap | 951 | 0.553 | 0.0838 | No |
| 9 | Ly75 | 990 | 0.548 | 0.0949 | No |
| 10 | Pf4 | 1024 | 0.542 | 0.1062 | No |
| 11 | Mmp9 | 1680 | 0.463 | 0.0891 | No |
| 12 | Traf2 | 1800 | 0.455 | 0.0946 | No |
| 13 | Prkcg | 2059 | 0.436 | 0.0938 | No |
| 14 | Bcl3 | 2323 | 0.413 | 0.0922 | No |
| 15 | Cdkn2a | 2431 | 0.406 | 0.0972 | No |
| 16 | Ets1 | 2695 | 0.388 | 0.0950 | No |
| 17 | Il4ra | 2742 | 0.386 | 0.1021 | No |
| 18 | Ccr2 | 2826 | 0.382 | 0.1074 | No |
| 19 | Il1b | 3201 | 0.356 | 0.0998 | No |
| 20 | Ccr5 | 3273 | 0.351 | 0.1050 | No |
| 21 | Lif | 3343 | 0.346 | 0.1101 | No |
| 22 | Il10 | 3460 | 0.340 | 0.1131 | No |
| 23 | Il2rg | 3616 | 0.331 | 0.1142 | No |
| 24 | Dyrk3 | 3618 | 0.331 | 0.1219 | No |
| 25 | Il18 | 3654 | 0.329 | 0.1281 | No |
| 26 | Fcgr2b | 3707 | 0.326 | 0.1335 | No |
| 27 | Itgb2 | 3718 | 0.326 | 0.1407 | No |
| 28 | F2 | 3729 | 0.325 | 0.1478 | No |
| 29 | Abce1 | 3764 | 0.321 | 0.1539 | No |
| 30 | Flna | 3850 | 0.316 | 0.1576 | No |
| 31 | Timp1 | 3952 | 0.310 | 0.1606 | No |
| 32 | Cd3d | 3974 | 0.309 | 0.1669 | No |
| 33 | Mrpl3 | 4291 | 0.293 | 0.1603 | No |
| 34 | Bcat1 | 4343 | 0.290 | 0.1649 | No |
| 35 | Cd79a | 4793 | 0.271 | 0.1521 | No |
| 36 | Lck | 4909 | 0.265 | 0.1533 | No |
| 37 | Galnt1 | 5035 | 0.258 | 0.1540 | No |
| 38 | Brca1 | 5039 | 0.257 | 0.1599 | No |
| 39 | Inhba | 5097 | 0.255 | 0.1634 | No |
| 40 | Cd4 | 5206 | 0.248 | 0.1646 | No |
| 41 | Apbb1 | 5276 | 0.245 | 0.1674 | No |
| 42 | Jak2 | 5312 | 0.243 | 0.1716 | No |
| 43 | Cd74 | 5364 | 0.241 | 0.1751 | No |
| 44 | Irf7 | 5560 | 0.231 | 0.1721 | No |
| 45 | Il2rb | 5627 | 0.229 | 0.1747 | No |
| 46 | Srgn | 5748 | 0.228 | 0.1749 | No |
| 47 | Tpd52 | 5991 | 0.215 | 0.1696 | No |
| 48 | Tnf | 6071 | 0.211 | 0.1712 | No |
| 49 | Cd80 | 6139 | 0.207 | 0.1731 | No |
| 50 | Ifngr1 | 6427 | 0.198 | 0.1655 | No |
| 51 | Icam1 | 6769 | 0.185 | 0.1553 | No |
| 52 | Ube2n | 6927 | 0.178 | 0.1528 | No |
| 53 | Fas | 7301 | 0.163 | 0.1407 | No |
| 54 | Hcls1 | 7790 | 0.142 | 0.1232 | No |
| 55 | Eif3j1 | 7882 | 0.139 | 0.1226 | No |
| 56 | Cd247 | 8068 | 0.132 | 0.1178 | No |
| 57 | Il27ra | 8222 | 0.126 | 0.1142 | No |
| 58 | Ptprc | 8254 | 0.125 | 0.1158 | No |
| 59 | Egfr | 8793 | 0.111 | 0.0954 | No |
| 60 | Nck1 | 8894 | 0.107 | 0.0937 | No |
| 61 | Map3k7 | 9223 | 0.094 | 0.0819 | No |
| 62 | Gcnt1 | 9339 | 0.091 | 0.0791 | No |
| 63 | Hif1a | 9475 | 0.086 | 0.0754 | No |
| 64 | Wars1 | 9949 | 0.068 | 0.0568 | No |
| 65 | Prkcb | 9959 | 0.068 | 0.0580 | No |
| 66 | Tlr6 | 10081 | 0.063 | 0.0543 | No |
| 67 | Ikbkb | 10228 | 0.058 | 0.0495 | No |
| 68 | Ncf4 | 10675 | 0.043 | 0.0315 | No |
| 69 | Npm1 | 10707 | 0.042 | 0.0311 | No |
| 70 | Abi1 | 10806 | 0.038 | 0.0278 | No |
| 71 | Eif3d | 10883 | 0.036 | 0.0254 | No |
| 72 | Ctss | 11063 | 0.030 | 0.0185 | No |
| 73 | Thy1 | 11304 | 0.022 | 0.0088 | No |
| 74 | Psmb10 | 11456 | 0.017 | 0.0027 | No |
| 75 | Cd40 | 12327 | -0.010 | -0.0341 | No |
| 76 | St8sia4 | 12695 | -0.023 | -0.0492 | No |
| 77 | Socs5 | 12725 | -0.023 | -0.0499 | No |
| 78 | Was | 12944 | -0.031 | -0.0584 | No |
| 79 | Eif4g3 | 12999 | -0.034 | -0.0600 | No |
| 80 | Itgal | 13152 | -0.039 | -0.0655 | No |
| 81 | Tapbp | 13171 | -0.039 | -0.0654 | No |
| 82 | Ifngr2 | 13402 | -0.048 | -0.0741 | No |
| 83 | Irf4 | 13751 | -0.059 | -0.0875 | No |
| 84 | Fgr | 14071 | -0.070 | -0.0995 | No |
| 85 | Il7 | 14078 | -0.070 | -0.0981 | No |
| 86 | Rps9 | 14111 | -0.071 | -0.0978 | No |
| 87 | Tlr2 | 14268 | -0.078 | -0.1026 | No |
| 88 | Ptpn6 | 14299 | -0.079 | -0.1021 | No |
| 89 | Tap1 | 14358 | -0.081 | -0.1026 | No |
| 90 | Il2ra | 14372 | -0.081 | -0.1013 | No |
| 91 | Rpl9 | 14398 | -0.082 | -0.1004 | No |
| 92 | C2 | 14553 | -0.089 | -0.1049 | No |
| 93 | Nlrp3 | 14633 | -0.091 | -0.1062 | No |
| 94 | Rps3a1 | 14739 | -0.095 | -0.1084 | No |
| 95 | Acvr2a | 14909 | -0.102 | -0.1132 | No |
| 96 | Cd47 | 15077 | -0.107 | -0.1179 | No |
| 97 | Nme1 | 15267 | -0.115 | -0.1232 | No |
| 98 | Elane | 15279 | -0.116 | -0.1210 | No |
| 99 | Map4k1 | 15586 | -0.127 | -0.1310 | No |
| 100 | Ltb | 15752 | -0.133 | -0.1350 | No |
| 101 | Il16 | 16024 | -0.143 | -0.1432 | No |
| 102 | Lcp2 | 16112 | -0.146 | -0.1435 | No |
| 103 | Gpr65 | 16151 | -0.147 | -0.1417 | No |
| 104 | Csk | 16314 | -0.153 | -0.1450 | No |
| 105 | Igsf6 | 16330 | -0.154 | -0.1420 | No |
| 106 | Stat1 | 16349 | -0.154 | -0.1392 | No |
| 107 | Ccr1 | 16502 | -0.160 | -0.1420 | No |
| 108 | Crtam | 16517 | -0.161 | -0.1388 | No |
| 109 | Lyn | 16548 | -0.162 | -0.1363 | No |
| 110 | Il12rb1 | 16669 | -0.168 | -0.1375 | No |
| 111 | Mtif2 | 17043 | -0.183 | -0.1491 | No |
| 112 | Eif5a | 17127 | -0.185 | -0.1483 | No |
| 113 | Rpl3l | 17188 | -0.186 | -0.1466 | No |
| 114 | Ccnd2 | 17240 | -0.187 | -0.1444 | No |
| 115 | Ache | 17247 | -0.187 | -0.1402 | No |
| 116 | Icosl | 17294 | -0.189 | -0.1378 | No |
| 117 | B2m | 17524 | -0.198 | -0.1429 | No |
| 118 | Elf4 | 17549 | -0.199 | -0.1393 | No |
| 119 | Nos2 | 17700 | -0.206 | -0.1409 | No |
| 120 | Cfp | 18160 | -0.222 | -0.1553 | No |
| 121 | Irf8 | 18399 | -0.233 | -0.1600 | No |
| 122 | Cd28 | 18683 | -0.245 | -0.1663 | No |
| 123 | Glmn | 18840 | -0.252 | -0.1671 | No |
| 124 | Csf1 | 18969 | -0.258 | -0.1665 | No |
| 125 | Tgfb2 | 19010 | -0.261 | -0.1621 | No |
| 126 | Bcl10 | 19493 | -0.283 | -0.1760 | Yes |
| 127 | Ube2d1 | 19644 | -0.291 | -0.1756 | Yes |
| 128 | Ripk2 | 19696 | -0.294 | -0.1710 | Yes |
| 129 | Il4 | 19754 | -0.298 | -0.1664 | Yes |
| 130 | Il15 | 19802 | -0.301 | -0.1614 | Yes |
| 131 | Ly86 | 19839 | -0.303 | -0.1559 | Yes |
| 132 | Ncr1 | 20210 | -0.319 | -0.1642 | Yes |
| 133 | Zap70 | 20297 | -0.324 | -0.1603 | Yes |
| 134 | Cxcr3 | 20416 | -0.331 | -0.1576 | Yes |
| 135 | Cd1d2 | 20693 | -0.350 | -0.1612 | Yes |
| 136 | Degs1 | 20746 | -0.353 | -0.1551 | Yes |
| 137 | Il12a | 20863 | -0.360 | -0.1517 | Yes |
| 138 | Hdac9 | 21011 | -0.370 | -0.1493 | Yes |
| 139 | Ccl5 | 21030 | -0.372 | -0.1414 | Yes |
| 140 | Ccnd3 | 21072 | -0.374 | -0.1344 | Yes |
| 141 | Tgfb1 | 21120 | -0.378 | -0.1276 | Yes |
| 142 | Spi1 | 21205 | -0.384 | -0.1222 | Yes |
| 143 | Tap2 | 21518 | -0.407 | -0.1260 | Yes |
| 144 | Gzmb | 21905 | -0.441 | -0.1321 | Yes |
| 145 | Tlr1 | 22002 | -0.447 | -0.1258 | Yes |
| 146 | Tlr3 | 22328 | -0.482 | -0.1284 | Yes |
| 147 | H2-Aa | 22377 | -0.487 | -0.1190 | Yes |
| 148 | Stat4 | 22447 | -0.494 | -0.1104 | Yes |
| 149 | H2-DMa | 22598 | -0.514 | -0.1048 | Yes |
| 150 | Cd96 | 22666 | -0.522 | -0.0955 | Yes |
| 151 | Il11 | 22750 | -0.536 | -0.0865 | Yes |
| 152 | H2-Oa | 22772 | -0.540 | -0.0748 | Yes |
| 153 | Il2 | 22939 | -0.569 | -0.0686 | Yes |
| 154 | Socs1 | 22945 | -0.569 | -0.0555 | Yes |
| 155 | Ifnar2 | 23024 | -0.590 | -0.0450 | Yes |
| 156 | H2-Ob | 23066 | -0.601 | -0.0328 | Yes |
| 157 | F2r | 23363 | -0.694 | -0.0292 | Yes |
| 158 | H2-DMb2 | 23505 | -0.800 | -0.0165 | Yes |
| 159 | Klrd1 | 23573 | -0.921 | 0.0022 | Yes |

