| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group3.GMP.mono_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.4560601 |
| Normalized Enrichment Score (NES) | 1.8114356 |
| Nominal p-value | 0.031936128 |
| FDR q-value | 0.109094195 |
| FWER p-Value | 0.062 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Hspa8 | 44 | 0.941 | 0.0211 | Yes |
| 2 | Srsf1 | 255 | 0.674 | 0.0286 | Yes |
| 3 | Kpnb1 | 328 | 0.634 | 0.0410 | Yes |
| 4 | Sap30 | 334 | 0.630 | 0.0562 | Yes |
| 5 | Dr1 | 351 | 0.624 | 0.0707 | Yes |
| 6 | Odc1 | 372 | 0.614 | 0.0849 | Yes |
| 7 | Lmnb1 | 810 | 0.513 | 0.0788 | Yes |
| 8 | Lbr | 884 | 0.500 | 0.0879 | Yes |
| 9 | Hnrnpd | 900 | 0.498 | 0.0994 | Yes |
| 10 | Hnrnpu | 945 | 0.492 | 0.1095 | Yes |
| 11 | Sqle | 1067 | 0.473 | 0.1159 | Yes |
| 12 | Bcl3 | 1211 | 0.459 | 0.1210 | Yes |
| 13 | Aurka | 1291 | 0.448 | 0.1286 | Yes |
| 14 | Ncl | 1386 | 0.440 | 0.1354 | Yes |
| 15 | Cdc6 | 1469 | 0.431 | 0.1424 | Yes |
| 16 | Nek2 | 1625 | 0.413 | 0.1459 | Yes |
| 17 | Mcm2 | 1629 | 0.413 | 0.1558 | Yes |
| 18 | Cdkn1b | 1691 | 0.408 | 0.1632 | Yes |
| 19 | Smc1a | 1731 | 0.404 | 0.1714 | Yes |
| 20 | Mcm3 | 1738 | 0.403 | 0.1810 | Yes |
| 21 | Tfdp1 | 1793 | 0.398 | 0.1884 | Yes |
| 22 | Nasp | 1870 | 0.393 | 0.1948 | Yes |
| 23 | Cdk1 | 1988 | 0.384 | 0.1992 | Yes |
| 24 | Cdc7 | 2373 | 0.354 | 0.1914 | Yes |
| 25 | Xpo1 | 2439 | 0.350 | 0.1972 | Yes |
| 26 | Nsd2 | 2472 | 0.347 | 0.2043 | Yes |
| 27 | Kif22 | 2508 | 0.346 | 0.2113 | Yes |
| 28 | Fbxo5 | 2544 | 0.344 | 0.2182 | Yes |
| 29 | Plk1 | 2589 | 0.340 | 0.2246 | Yes |
| 30 | Tnpo2 | 2661 | 0.335 | 0.2298 | Yes |
| 31 | Ddx39a | 2753 | 0.328 | 0.2339 | Yes |
| 32 | Incenp | 2877 | 0.320 | 0.2365 | Yes |
| 33 | Kif11 | 2922 | 0.316 | 0.2423 | Yes |
| 34 | Nolc1 | 2990 | 0.312 | 0.2471 | Yes |
| 35 | Ttk | 3200 | 0.303 | 0.2456 | Yes |
| 36 | Racgap1 | 3238 | 0.301 | 0.2513 | Yes |
| 37 | Kif4 | 3243 | 0.300 | 0.2585 | Yes |
| 38 | Cdkn2c | 3259 | 0.300 | 0.2652 | Yes |
| 39 | Prc1 | 3334 | 0.295 | 0.2692 | Yes |
| 40 | Top2a | 3338 | 0.295 | 0.2763 | Yes |
| 41 | Cks2 | 3583 | 0.284 | 0.2728 | Yes |
| 42 | Ccna2 | 3666 | 0.279 | 0.2762 | Yes |
| 43 | Sfpq | 3691 | 0.278 | 0.2819 | Yes |
| 44 | Mybl2 | 3707 | 0.277 | 0.2880 | Yes |
| 45 | Mad2l1 | 3814 | 0.272 | 0.2902 | Yes |
| 46 | G3bp1 | 3838 | 0.270 | 0.2958 | Yes |
| 47 | Snrpd1 | 3901 | 0.267 | 0.2996 | Yes |
| 48 | E2f2 | 4003 | 0.261 | 0.3017 | Yes |
| 49 | Uck2 | 4049 | 0.259 | 0.3061 | Yes |
| 50 | Suv39h1 | 4062 | 0.258 | 0.3119 | Yes |
| 51 | Upf1 | 4201 | 0.251 | 0.3121 | Yes |
| 52 | Cenpe | 4336 | 0.244 | 0.3124 | Yes |
| 53 | Kif2c | 4350 | 0.243 | 0.3178 | Yes |
| 54 | Chaf1a | 4366 | 0.242 | 0.3230 | Yes |
| 55 | Syncrip | 4374 | 0.242 | 0.3287 | Yes |
| 56 | Mcm6 | 4621 | 0.230 | 0.3238 | Yes |
| 57 | Cul1 | 4691 | 0.229 | 0.3264 | Yes |
| 58 | Pttg1 | 4772 | 0.226 | 0.3285 | Yes |
| 59 | Tpx2 | 4791 | 0.226 | 0.3333 | Yes |
| 60 | Abl1 | 4839 | 0.223 | 0.3367 | Yes |
| 61 | Tle3 | 4856 | 0.223 | 0.3415 | Yes |
| 62 | Hmmr | 4865 | 0.222 | 0.3466 | Yes |
| 63 | Hif1a | 4923 | 0.219 | 0.3495 | Yes |
| 64 | Tent4a | 4969 | 0.217 | 0.3529 | Yes |
| 65 | Plk4 | 5006 | 0.214 | 0.3566 | Yes |
| 66 | Hira | 5025 | 0.214 | 0.3610 | Yes |
| 67 | Mki67 | 5060 | 0.212 | 0.3647 | Yes |
| 68 | Cdc25a | 5075 | 0.212 | 0.3693 | Yes |
| 69 | Numa1 | 5161 | 0.207 | 0.3708 | Yes |
| 70 | Amd1 | 5167 | 0.207 | 0.3756 | Yes |
| 71 | Notch2 | 5207 | 0.205 | 0.3790 | Yes |
| 72 | Birc5 | 5211 | 0.205 | 0.3838 | Yes |
| 73 | Smarcc1 | 5280 | 0.202 | 0.3859 | Yes |
| 74 | Smc2 | 5362 | 0.199 | 0.3873 | Yes |
| 75 | Cdc25b | 5365 | 0.199 | 0.3921 | Yes |
| 76 | Kif23 | 5415 | 0.197 | 0.3948 | Yes |
| 77 | Pafah1b1 | 5438 | 0.196 | 0.3986 | Yes |
| 78 | Gspt1 | 5546 | 0.191 | 0.3987 | Yes |
| 79 | Chmp1a | 5699 | 0.185 | 0.3968 | Yes |
| 80 | Slc7a5 | 5728 | 0.184 | 0.4001 | Yes |
| 81 | H2bc12 | 5746 | 0.183 | 0.4038 | Yes |
| 82 | Kif5b | 5788 | 0.182 | 0.4065 | Yes |
| 83 | Tmpo | 5895 | 0.178 | 0.4064 | Yes |
| 84 | Kif15 | 5943 | 0.175 | 0.4086 | Yes |
| 85 | Mcm5 | 6020 | 0.173 | 0.4096 | Yes |
| 86 | Rad54l | 6025 | 0.172 | 0.4136 | Yes |
| 87 | Tacc3 | 6033 | 0.172 | 0.4176 | Yes |
| 88 | Slc38a1 | 6041 | 0.172 | 0.4215 | Yes |
| 89 | Dbf4 | 6143 | 0.168 | 0.4212 | Yes |
| 90 | Bub1 | 6162 | 0.167 | 0.4246 | Yes |
| 91 | Ythdc1 | 6181 | 0.167 | 0.4279 | Yes |
| 92 | Rad21 | 6230 | 0.165 | 0.4298 | Yes |
| 93 | Nup50 | 6311 | 0.162 | 0.4304 | Yes |
| 94 | Kif20b | 6330 | 0.161 | 0.4336 | Yes |
| 95 | Lig3 | 6354 | 0.160 | 0.4365 | Yes |
| 96 | Cbx1 | 6397 | 0.159 | 0.4386 | Yes |
| 97 | E2f3 | 6465 | 0.156 | 0.4395 | Yes |
| 98 | Rad23b | 6484 | 0.155 | 0.4426 | Yes |
| 99 | Tra2b | 6534 | 0.153 | 0.4442 | Yes |
| 100 | Cul3 | 6630 | 0.150 | 0.4438 | Yes |
| 101 | Espl1 | 6678 | 0.148 | 0.4454 | Yes |
| 102 | Cul4a | 6802 | 0.143 | 0.4437 | Yes |
| 103 | Top1 | 6843 | 0.142 | 0.4454 | Yes |
| 104 | Gins2 | 6963 | 0.137 | 0.4437 | Yes |
| 105 | Ilf3 | 7014 | 0.136 | 0.4449 | Yes |
| 106 | Wrn | 7019 | 0.135 | 0.4480 | Yes |
| 107 | Rasal2 | 7028 | 0.135 | 0.4510 | Yes |
| 108 | Odf2 | 7172 | 0.129 | 0.4480 | Yes |
| 109 | Pbk | 7194 | 0.128 | 0.4503 | Yes |
| 110 | Ndc80 | 7233 | 0.127 | 0.4517 | Yes |
| 111 | Srsf10 | 7253 | 0.126 | 0.4540 | Yes |
| 112 | Exo1 | 7277 | 0.125 | 0.4561 | Yes |
| 113 | Egf | 7500 | 0.121 | 0.4495 | No |
| 114 | Cdc27 | 7582 | 0.117 | 0.4489 | No |
| 115 | Mtf2 | 7887 | 0.107 | 0.4386 | No |
| 116 | Arid4a | 8015 | 0.103 | 0.4357 | No |
| 117 | Polq | 8044 | 0.102 | 0.4370 | No |
| 118 | Cenpf | 8123 | 0.099 | 0.4361 | No |
| 119 | Prmt5 | 8211 | 0.096 | 0.4347 | No |
| 120 | Dkc1 | 8290 | 0.094 | 0.4337 | No |
| 121 | Map3k20 | 8317 | 0.093 | 0.4348 | No |
| 122 | Ccnt1 | 8414 | 0.090 | 0.4329 | No |
| 123 | Traip | 8432 | 0.089 | 0.4344 | No |
| 124 | Chek1 | 8662 | 0.082 | 0.4266 | No |
| 125 | Mnat1 | 8700 | 0.080 | 0.4270 | No |
| 126 | Prpf4b | 8786 | 0.077 | 0.4252 | No |
| 127 | Ctcf | 8792 | 0.077 | 0.4269 | No |
| 128 | Ezh2 | 8838 | 0.075 | 0.4268 | No |
| 129 | Casp8ap2 | 8861 | 0.075 | 0.4277 | No |
| 130 | Aurkb | 8980 | 0.071 | 0.4244 | No |
| 131 | E2f1 | 9192 | 0.064 | 0.4170 | No |
| 132 | Cul5 | 9297 | 0.060 | 0.4140 | No |
| 133 | Stag1 | 9425 | 0.056 | 0.4099 | No |
| 134 | Bard1 | 9480 | 0.054 | 0.4090 | No |
| 135 | Rbl1 | 9602 | 0.050 | 0.4050 | No |
| 136 | Slc7a1 | 9612 | 0.050 | 0.4059 | No |
| 137 | Kmt5a | 9900 | 0.041 | 0.3946 | No |
| 138 | Pds5b | 10005 | 0.038 | 0.3911 | No |
| 139 | Pola2 | 10260 | 0.031 | 0.3811 | No |
| 140 | Hmgb3 | 10272 | 0.030 | 0.3813 | No |
| 141 | Stil | 10283 | 0.030 | 0.3816 | No |
| 142 | Slc12a2 | 10330 | 0.029 | 0.3804 | No |
| 143 | Ewsr1 | 10428 | 0.026 | 0.3769 | No |
| 144 | Meis2 | 10907 | 0.011 | 0.3568 | No |
| 145 | Pole | 10922 | 0.011 | 0.3564 | No |
| 146 | E2f4 | 10935 | 0.011 | 0.3562 | No |
| 147 | Ccnf | 10945 | 0.010 | 0.3560 | No |
| 148 | Smc4 | 10948 | 0.010 | 0.3562 | No |
| 149 | H2az1 | 10990 | 0.008 | 0.3546 | No |
| 150 | Katna1 | 11028 | 0.007 | 0.3532 | No |
| 151 | Mapk14 | 11178 | 0.003 | 0.3470 | No |
| 152 | Dtymk | 11228 | 0.002 | 0.3449 | No |
| 153 | Atrx | 11940 | -0.019 | 0.3150 | No |
| 154 | Ube2s | 11956 | -0.020 | 0.3149 | No |
| 155 | Cdk4 | 12016 | -0.021 | 0.3129 | No |
| 156 | Nup98 | 12017 | -0.021 | 0.3134 | No |
| 157 | Bub3 | 12123 | -0.025 | 0.3095 | No |
| 158 | Stmn1 | 12174 | -0.026 | 0.3080 | No |
| 159 | Nusap1 | 12389 | -0.033 | 0.2997 | No |
| 160 | Knl1 | 12539 | -0.037 | 0.2943 | No |
| 161 | Jpt1 | 12800 | -0.046 | 0.2843 | No |
| 162 | Meis1 | 13031 | -0.055 | 0.2758 | No |
| 163 | Orc6 | 13192 | -0.060 | 0.2704 | No |
| 164 | Ss18 | 13681 | -0.077 | 0.2515 | No |
| 165 | Orc5 | 13727 | -0.079 | 0.2515 | No |
| 166 | Cdc20 | 13801 | -0.081 | 0.2504 | No |
| 167 | Fancc | 13841 | -0.082 | 0.2507 | No |
| 168 | Cenpa | 14015 | -0.088 | 0.2455 | No |
| 169 | Foxn3 | 14362 | -0.099 | 0.2331 | No |
| 170 | Prim2 | 14780 | -0.112 | 0.2181 | No |
| 171 | Pml | 14904 | -0.117 | 0.2157 | No |
| 172 | Atf5 | 15680 | -0.143 | 0.1861 | No |
| 173 | Rps6ka5 | 15889 | -0.152 | 0.1809 | No |
| 174 | Hus1 | 16279 | -0.165 | 0.1684 | No |
| 175 | Cdc45 | 16428 | -0.171 | 0.1662 | No |
| 176 | Efna5 | 16602 | -0.177 | 0.1632 | No |
| 177 | Cks1b | 16692 | -0.180 | 0.1638 | No |
| 178 | Marcks | 17465 | -0.211 | 0.1360 | No |
| 179 | Pura | 17520 | -0.213 | 0.1389 | No |
| 180 | Tgfb1 | 17728 | -0.221 | 0.1354 | No |
| 181 | Rpa2 | 17849 | -0.227 | 0.1359 | No |
| 182 | H2ax | 18175 | -0.241 | 0.1279 | No |
| 183 | Dmd | 18249 | -0.244 | 0.1307 | No |
| 184 | Srsf2 | 18259 | -0.244 | 0.1363 | No |
| 185 | Troap | 18380 | -0.250 | 0.1373 | No |
| 186 | Ccnb2 | 18733 | -0.264 | 0.1287 | No |
| 187 | Smad3 | 18786 | -0.267 | 0.1330 | No |
| 188 | Brca2 | 18867 | -0.270 | 0.1362 | No |
| 189 | Myc | 20453 | -0.356 | 0.0773 | No |
| 190 | Ube2c | 20644 | -0.367 | 0.0781 | No |
| 191 | H2az2 | 20676 | -0.369 | 0.0858 | No |
| 192 | Hmga1b | 21257 | -0.408 | 0.0710 | No |
| 193 | Ccnd1 | 22105 | -0.483 | 0.0467 | No |
| 194 | Cdkn3 | 23329 | -0.742 | 0.0126 | No |

