| Dataset | GMP.GMP.mono_Pheno.cls #Group2_versus_Group3.GMP.mono_Pheno.cls #Group2_versus_Group3_repos |
| Phenotype | GMP.mono_Pheno.cls#Group2_versus_Group3_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.4307757 |
| Normalized Enrichment Score (NES) | 1.5452673 |
| Nominal p-value | 0.112426035 |
| FDR q-value | 0.1684481 |
| FWER p-Value | 0.351 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dck | 117 | 0.774 | 0.0140 | Yes |
| 2 | Tfrc | 218 | 0.697 | 0.0269 | Yes |
| 3 | Srsf1 | 255 | 0.674 | 0.0419 | Yes |
| 4 | Ipo7 | 648 | 0.543 | 0.0386 | Yes |
| 5 | Dnmt1 | 651 | 0.542 | 0.0518 | Yes |
| 6 | Lmnb1 | 810 | 0.513 | 0.0577 | Yes |
| 7 | Lbr | 884 | 0.500 | 0.0669 | Yes |
| 8 | Rbbp7 | 897 | 0.498 | 0.0786 | Yes |
| 9 | Hnrnpd | 900 | 0.498 | 0.0908 | Yes |
| 10 | Aurka | 1291 | 0.448 | 0.0851 | Yes |
| 11 | Rrm2 | 1350 | 0.441 | 0.0935 | Yes |
| 12 | Anp32e | 1464 | 0.432 | 0.0993 | Yes |
| 13 | Slbp | 1506 | 0.427 | 0.1081 | Yes |
| 14 | Bub1b | 1546 | 0.423 | 0.1168 | Yes |
| 15 | Mcm2 | 1629 | 0.413 | 0.1235 | Yes |
| 16 | Cdkn1b | 1691 | 0.408 | 0.1309 | Yes |
| 17 | Prps1 | 1702 | 0.407 | 0.1405 | Yes |
| 18 | Smc1a | 1731 | 0.404 | 0.1492 | Yes |
| 19 | Mcm3 | 1738 | 0.403 | 0.1589 | Yes |
| 20 | Ccp110 | 1787 | 0.399 | 0.1666 | Yes |
| 21 | Nasp | 1870 | 0.393 | 0.1728 | Yes |
| 22 | Ccne1 | 1893 | 0.391 | 0.1815 | Yes |
| 23 | Cdk1 | 1988 | 0.384 | 0.1869 | Yes |
| 24 | Phf5a | 2141 | 0.371 | 0.1895 | Yes |
| 25 | Smc3 | 2206 | 0.366 | 0.1958 | Yes |
| 26 | Mcm4 | 2234 | 0.364 | 0.2036 | Yes |
| 27 | Cse1l | 2435 | 0.350 | 0.2037 | Yes |
| 28 | Xpo1 | 2439 | 0.350 | 0.2121 | Yes |
| 29 | Kif22 | 2508 | 0.346 | 0.2177 | Yes |
| 30 | Plk1 | 2589 | 0.340 | 0.2227 | Yes |
| 31 | Ddx39a | 2753 | 0.328 | 0.2238 | Yes |
| 32 | Mcm7 | 2884 | 0.319 | 0.2261 | Yes |
| 33 | Nap1l1 | 2973 | 0.313 | 0.2301 | Yes |
| 34 | Nolc1 | 2990 | 0.312 | 0.2371 | Yes |
| 35 | Ssrp1 | 3175 | 0.304 | 0.2367 | Yes |
| 36 | Racgap1 | 3238 | 0.301 | 0.2414 | Yes |
| 37 | Kif4 | 3243 | 0.300 | 0.2486 | Yes |
| 38 | Cdkn2c | 3259 | 0.300 | 0.2554 | Yes |
| 39 | Cdca8 | 3268 | 0.299 | 0.2624 | Yes |
| 40 | Hells | 3296 | 0.297 | 0.2685 | Yes |
| 41 | Top2a | 3338 | 0.295 | 0.2740 | Yes |
| 42 | Brca1 | 3395 | 0.291 | 0.2788 | Yes |
| 43 | Cks2 | 3583 | 0.284 | 0.2778 | Yes |
| 44 | Pnn | 3611 | 0.282 | 0.2836 | Yes |
| 45 | Rad51c | 3676 | 0.279 | 0.2877 | Yes |
| 46 | Ubr7 | 3686 | 0.278 | 0.2942 | Yes |
| 47 | Mybl2 | 3707 | 0.277 | 0.3001 | Yes |
| 48 | Msh2 | 3743 | 0.275 | 0.3054 | Yes |
| 49 | Ran | 3758 | 0.274 | 0.3115 | Yes |
| 50 | Dlgap5 | 3787 | 0.272 | 0.3170 | Yes |
| 51 | Mad2l1 | 3814 | 0.272 | 0.3226 | Yes |
| 52 | Eif2s1 | 3877 | 0.268 | 0.3265 | Yes |
| 53 | Zw10 | 4009 | 0.261 | 0.3273 | Yes |
| 54 | Lyar | 4032 | 0.260 | 0.3328 | Yes |
| 55 | Suv39h1 | 4062 | 0.258 | 0.3379 | Yes |
| 56 | Lsm8 | 4243 | 0.249 | 0.3363 | Yes |
| 57 | Cenpe | 4336 | 0.244 | 0.3384 | Yes |
| 58 | Kif2c | 4350 | 0.243 | 0.3438 | Yes |
| 59 | Syncrip | 4374 | 0.242 | 0.3488 | Yes |
| 60 | Ncapd2 | 4426 | 0.239 | 0.3525 | Yes |
| 61 | Hmgb2 | 4539 | 0.233 | 0.3534 | Yes |
| 62 | Smc6 | 4569 | 0.232 | 0.3579 | Yes |
| 63 | Atad2 | 4601 | 0.231 | 0.3623 | Yes |
| 64 | Mcm6 | 4621 | 0.230 | 0.3671 | Yes |
| 65 | Pcna | 4628 | 0.230 | 0.3725 | Yes |
| 66 | Pttg1 | 4772 | 0.226 | 0.3719 | Yes |
| 67 | Eed | 4774 | 0.226 | 0.3775 | Yes |
| 68 | Usp1 | 4809 | 0.225 | 0.3815 | Yes |
| 69 | Hmmr | 4865 | 0.222 | 0.3846 | Yes |
| 70 | Nme1 | 4891 | 0.221 | 0.3890 | Yes |
| 71 | E2f8 | 4955 | 0.218 | 0.3917 | Yes |
| 72 | Shmt1 | 4965 | 0.217 | 0.3966 | Yes |
| 73 | Nup107 | 4968 | 0.217 | 0.4019 | Yes |
| 74 | Plk4 | 5006 | 0.214 | 0.4056 | Yes |
| 75 | Mki67 | 5060 | 0.212 | 0.4085 | Yes |
| 76 | Cdc25a | 5075 | 0.212 | 0.4131 | Yes |
| 77 | Tbrg4 | 5174 | 0.207 | 0.4140 | Yes |
| 78 | Birc5 | 5211 | 0.205 | 0.4175 | Yes |
| 79 | Cdc25b | 5365 | 0.199 | 0.4159 | Yes |
| 80 | Gspt1 | 5546 | 0.191 | 0.4129 | Yes |
| 81 | Cbx5 | 5585 | 0.190 | 0.4160 | Yes |
| 82 | Tmpo | 5895 | 0.178 | 0.4071 | Yes |
| 83 | Pa2g4 | 5900 | 0.178 | 0.4113 | Yes |
| 84 | Nup205 | 5910 | 0.177 | 0.4153 | Yes |
| 85 | Ppp1r8 | 5913 | 0.177 | 0.4196 | Yes |
| 86 | Ak2 | 5944 | 0.175 | 0.4226 | Yes |
| 87 | Mcm5 | 6020 | 0.173 | 0.4237 | Yes |
| 88 | Tacc3 | 6033 | 0.172 | 0.4274 | Yes |
| 89 | Prkdc | 6053 | 0.171 | 0.4308 | Yes |
| 90 | Rad21 | 6230 | 0.165 | 0.4273 | No |
| 91 | Ranbp1 | 6257 | 0.164 | 0.4302 | No |
| 92 | Lig1 | 6371 | 0.160 | 0.4293 | No |
| 93 | Tra2b | 6534 | 0.153 | 0.4262 | No |
| 94 | Rpa1 | 6670 | 0.148 | 0.4241 | No |
| 95 | Espl1 | 6678 | 0.148 | 0.4274 | No |
| 96 | Nup153 | 6719 | 0.146 | 0.4293 | No |
| 97 | Ilf3 | 7014 | 0.136 | 0.4201 | No |
| 98 | Cit | 7230 | 0.127 | 0.4140 | No |
| 99 | Mthfd2 | 7252 | 0.126 | 0.4162 | No |
| 100 | Pan2 | 7443 | 0.123 | 0.4111 | No |
| 101 | Spag5 | 7487 | 0.121 | 0.4123 | No |
| 102 | Dut | 7544 | 0.119 | 0.4128 | No |
| 103 | Pole4 | 7642 | 0.115 | 0.4115 | No |
| 104 | Xrcc6 | 7712 | 0.113 | 0.4113 | No |
| 105 | Orc2 | 7796 | 0.111 | 0.4105 | No |
| 106 | Rad51ap1 | 7945 | 0.105 | 0.4068 | No |
| 107 | Cnot9 | 8119 | 0.100 | 0.4018 | No |
| 108 | Timeless | 8336 | 0.092 | 0.3949 | No |
| 109 | Rad50 | 8552 | 0.085 | 0.3878 | No |
| 110 | Paics | 8562 | 0.084 | 0.3895 | No |
| 111 | Chek1 | 8662 | 0.082 | 0.3873 | No |
| 112 | Mre11a | 8784 | 0.077 | 0.3840 | No |
| 113 | Psip1 | 8788 | 0.077 | 0.3858 | No |
| 114 | Ctcf | 8792 | 0.077 | 0.3875 | No |
| 115 | Spc25 | 8815 | 0.076 | 0.3884 | No |
| 116 | Ezh2 | 8838 | 0.075 | 0.3894 | No |
| 117 | Aurkb | 8980 | 0.071 | 0.3851 | No |
| 118 | Tubb5 | 8983 | 0.071 | 0.3867 | No |
| 119 | Tipin | 8991 | 0.070 | 0.3882 | No |
| 120 | Nop56 | 9074 | 0.068 | 0.3863 | No |
| 121 | Rfc3 | 9356 | 0.059 | 0.3758 | No |
| 122 | Stag1 | 9425 | 0.056 | 0.3743 | No |
| 123 | Tcf19 | 9467 | 0.055 | 0.3739 | No |
| 124 | Bard1 | 9480 | 0.054 | 0.3747 | No |
| 125 | Melk | 9746 | 0.046 | 0.3645 | No |
| 126 | Nbn | 9878 | 0.042 | 0.3600 | No |
| 127 | Chek2 | 9969 | 0.040 | 0.3571 | No |
| 128 | Pds5b | 10005 | 0.038 | 0.3565 | No |
| 129 | Rfc1 | 10162 | 0.034 | 0.3507 | No |
| 130 | Rpa3 | 10193 | 0.033 | 0.3503 | No |
| 131 | Pola2 | 10260 | 0.031 | 0.3482 | No |
| 132 | Hmgb3 | 10272 | 0.030 | 0.3485 | No |
| 133 | Pole | 10922 | 0.011 | 0.3210 | No |
| 134 | Smc4 | 10948 | 0.010 | 0.3202 | No |
| 135 | H2az1 | 10990 | 0.008 | 0.3187 | No |
| 136 | Trip13 | 11213 | 0.002 | 0.3093 | No |
| 137 | Mms22l | 11218 | 0.002 | 0.3091 | No |
| 138 | Luc7l3 | 11259 | 0.001 | 0.3074 | No |
| 139 | Wee1 | 11261 | 0.001 | 0.3074 | No |
| 140 | Dek | 11488 | -0.004 | 0.2979 | No |
| 141 | Pms2 | 11500 | -0.005 | 0.2975 | No |
| 142 | Dclre1b | 11540 | -0.006 | 0.2960 | No |
| 143 | Depdc1a | 11742 | -0.013 | 0.2878 | No |
| 144 | Psmc3ip | 11814 | -0.016 | 0.2851 | No |
| 145 | Asf1a | 11893 | -0.018 | 0.2822 | No |
| 146 | Ube2s | 11956 | -0.020 | 0.2801 | No |
| 147 | Rad1 | 12003 | -0.021 | 0.2786 | No |
| 148 | Cdk4 | 12016 | -0.021 | 0.2786 | No |
| 149 | Gins1 | 12065 | -0.023 | 0.2772 | No |
| 150 | Brms1l | 12066 | -0.023 | 0.2777 | No |
| 151 | Stmn1 | 12174 | -0.026 | 0.2738 | No |
| 152 | Diaph3 | 12249 | -0.028 | 0.2713 | No |
| 153 | Dctpp1 | 12283 | -0.029 | 0.2707 | No |
| 154 | Gins4 | 12304 | -0.030 | 0.2705 | No |
| 155 | Ing3 | 12458 | -0.035 | 0.2649 | No |
| 156 | Pold3 | 12653 | -0.041 | 0.2576 | No |
| 157 | Jpt1 | 12800 | -0.046 | 0.2525 | No |
| 158 | Orc6 | 13192 | -0.060 | 0.2373 | No |
| 159 | Exosc8 | 13325 | -0.065 | 0.2333 | No |
| 160 | Trp53 | 13333 | -0.065 | 0.2346 | No |
| 161 | Cdc20 | 13801 | -0.081 | 0.2166 | No |
| 162 | Donson | 13846 | -0.082 | 0.2168 | No |
| 163 | Cdkn1a | 13944 | -0.086 | 0.2147 | No |
| 164 | Gins3 | 14368 | -0.099 | 0.1991 | No |
| 165 | Rnaseh2a | 14407 | -0.101 | 0.2000 | No |
| 166 | Nudt21 | 14422 | -0.101 | 0.2019 | No |
| 167 | Pold2 | 14575 | -0.104 | 0.1979 | No |
| 168 | Mlh1 | 14754 | -0.111 | 0.1931 | No |
| 169 | Prim2 | 14780 | -0.112 | 0.1948 | No |
| 170 | Spc24 | 15015 | -0.120 | 0.1877 | No |
| 171 | Kif18b | 15101 | -0.123 | 0.1871 | No |
| 172 | Ppm1d | 15139 | -0.124 | 0.1886 | No |
| 173 | Ube2t | 15499 | -0.137 | 0.1767 | No |
| 174 | Snrpb | 15553 | -0.139 | 0.1778 | No |
| 175 | Pop7 | 15948 | -0.154 | 0.1648 | No |
| 176 | Cdkn2a | 16274 | -0.165 | 0.1550 | No |
| 177 | Hus1 | 16279 | -0.165 | 0.1589 | No |
| 178 | Prdx4 | 16406 | -0.170 | 0.1577 | No |
| 179 | Asf1b | 16498 | -0.172 | 0.1580 | No |
| 180 | Tk1 | 16570 | -0.175 | 0.1593 | No |
| 181 | Cks1b | 16692 | -0.180 | 0.1586 | No |
| 182 | Pold1 | 17664 | -0.219 | 0.1225 | No |
| 183 | Rpa2 | 17849 | -0.227 | 0.1202 | No |
| 184 | Ung | 17944 | -0.232 | 0.1219 | No |
| 185 | H2ax | 18175 | -0.241 | 0.1180 | No |
| 186 | Srsf2 | 18259 | -0.244 | 0.1205 | No |
| 187 | Ccnb2 | 18733 | -0.264 | 0.1068 | No |
| 188 | Brca2 | 18867 | -0.270 | 0.1077 | No |
| 189 | Dscc1 | 19712 | -0.312 | 0.0794 | No |
| 190 | Tubg1 | 19744 | -0.313 | 0.0858 | No |
| 191 | Wdr90 | 19799 | -0.317 | 0.0912 | No |
| 192 | Cenpm | 19889 | -0.321 | 0.0953 | No |
| 193 | Rfc2 | 20223 | -0.342 | 0.0895 | No |
| 194 | Myc | 20453 | -0.356 | 0.0885 | No |
| 195 | Mxd3 | 20622 | -0.365 | 0.0903 | No |
| 196 | Cdca3 | 20916 | -0.385 | 0.0872 | No |
| 197 | Hmga1b | 21257 | -0.408 | 0.0828 | No |
| 198 | Cdkn3 | 23329 | -0.742 | 0.0126 | No |

