Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group4.GMP.mono_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_TGF_BETA_SIGNALING |
| Enrichment Score (ES) | -0.2596183 |
| Normalized Enrichment Score (NES) | -1.1243072 |
| Nominal p-value | 0.31445312 |
| FDR q-value | 0.46379507 |
| FWER p-Value | 0.96 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ski | 1378 | 0.501 | 0.0027 | No |
| 2 | Sptbn1 | 1583 | 0.472 | 0.0515 | No |
| 3 | Ppm1a | 3465 | 0.336 | 0.0127 | No |
| 4 | Map3k7 | 6410 | 0.198 | -0.0881 | No |
| 5 | Ncor2 | 6941 | 0.180 | -0.0886 | No |
| 6 | Cdk9 | 7508 | 0.159 | -0.0932 | No |
| 7 | Wwtr1 | 7814 | 0.147 | -0.0882 | No |
| 8 | Smad7 | 8302 | 0.128 | -0.0933 | No |
| 9 | Rab31 | 9019 | 0.100 | -0.1114 | No |
| 10 | Smurf2 | 9471 | 0.086 | -0.1201 | No |
| 11 | Ctnnb1 | 9534 | 0.083 | -0.1126 | No |
| 12 | Smad3 | 9665 | 0.079 | -0.1085 | No |
| 13 | Thbs1 | 9738 | 0.076 | -0.1023 | No |
| 14 | Smad6 | 9914 | 0.070 | -0.1012 | No |
| 15 | Skil | 10018 | 0.065 | -0.0976 | No |
| 16 | Xiap | 10281 | 0.056 | -0.1019 | No |
| 17 | Hdac1 | 10412 | 0.051 | -0.1011 | No |
| 18 | Fkbp1a | 10441 | 0.050 | -0.0962 | No |
| 19 | Hipk2 | 10869 | 0.034 | -0.1102 | No |
| 20 | Slc20a1 | 10946 | 0.031 | -0.1096 | No |
| 21 | Ube2d3 | 10955 | 0.031 | -0.1062 | No |
| 22 | Smurf1 | 11221 | 0.023 | -0.1146 | No |
| 23 | Furin | 11818 | 0.004 | -0.1395 | No |
| 24 | Trim33 | 12473 | -0.010 | -0.1659 | No |
| 25 | Ifngr2 | 12632 | -0.015 | -0.1708 | No |
| 26 | Rhoa | 12973 | -0.028 | -0.1818 | No |
| 27 | Fnta | 13478 | -0.045 | -0.1976 | No |
| 28 | Klf10 | 13554 | -0.048 | -0.1950 | No |
| 29 | Ppp1r15a | 13845 | -0.057 | -0.2003 | No |
| 30 | Tgif1 | 14131 | -0.068 | -0.2041 | No |
| 31 | Smad1 | 14659 | -0.086 | -0.2160 | No |
| 32 | Apc | 14667 | -0.087 | -0.2057 | No |
| 33 | Acvr1 | 14729 | -0.089 | -0.1975 | No |
| 34 | Junb | 15208 | -0.107 | -0.2047 | No |
| 35 | Cdkn1c | 15304 | -0.110 | -0.1953 | No |
| 36 | Ltbp2 | 15642 | -0.122 | -0.1947 | No |
| 37 | Pmepa1 | 15769 | -0.127 | -0.1846 | No |
| 38 | Arid4b | 15862 | -0.131 | -0.1725 | No |
| 39 | Id1 | 15982 | -0.136 | -0.1609 | No |
| 40 | Bmpr2 | 16967 | -0.173 | -0.1816 | No |
| 41 | Tgfbr1 | 17429 | -0.191 | -0.1778 | No |
| 42 | Bmpr1a | 18277 | -0.224 | -0.1865 | No |
| 43 | Cdh1 | 20002 | -0.311 | -0.2217 | Yes |
| 44 | Tjp1 | 20846 | -0.359 | -0.2137 | Yes |
| 45 | Tgfb1 | 21043 | -0.373 | -0.1765 | Yes |
| 46 | Eng | 21886 | -0.440 | -0.1586 | Yes |
| 47 | Bcar3 | 22056 | -0.457 | -0.1100 | Yes |
| 48 | Ppp1ca | 23256 | -0.656 | -0.0809 | Yes |
| 49 | Id2 | 23495 | -0.791 | 0.0055 | Yes |
