Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group1_versus_Group4.GMP.mono_Pheno.cls #Group1_versus_Group4_repos
Phenotype	GMP.mono_Pheno.cls#Group1_versus_Group4_repos
Upregulated in class	3
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.27649036
Normalized Enrichment Score (NES)	-1.1644433
Nominal p-value	0.28343314
FDR q-value	0.46617767
FWER p-Value	0.948

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Plk2	186	0.826	0.0099	No
2	Tgfa	470	0.678	0.0125	No
3	Stom	656	0.616	0.0179	No
4	H2ac25	736	0.597	0.0275	No
5	Fos	777	0.588	0.0385	No
6	Ephx1	813	0.580	0.0496	No
7	Tchh	905	0.564	0.0579	No
8	Csrnp2	1226	0.526	0.0556	No
9	Jun	1580	0.472	0.0507	No
10	Cd82	1627	0.466	0.0588	No
11	Baiap2	1986	0.428	0.0528	No
12	Apaf1	2411	0.398	0.0433	No
13	Txnip	2468	0.392	0.0494	No
14	Lif	2868	0.370	0.0404	No
15	Fdxr	3012	0.362	0.0421	No
16	Hexim1	3175	0.352	0.0428	No
17	Osgin1	3409	0.340	0.0402	No
18	Ldhb	3489	0.334	0.0441	No
19	Ccp110	3805	0.315	0.0375	No
20	Cdkn2a	4089	0.298	0.0318	No
21	Trp63	4133	0.295	0.0364	No
22	Abcc5	4135	0.295	0.0427	No
23	Ak1	4213	0.292	0.0458	No
24	Rab40c	4215	0.292	0.0520	No
25	Foxo3	4271	0.288	0.0559	No
26	Tspyl2	4988	0.251	0.0308	No
27	H1f2	5234	0.239	0.0255	No
28	Polh	5672	0.224	0.0117	No
29	Perp	5798	0.218	0.0111	No
30	Ip6k2	6270	0.203	-0.0046	No
31	Tob1	6329	0.201	-0.0027	No
32	Fbxw7	6364	0.200	0.0001	No
33	Blcap	6672	0.191	-0.0088	No
34	Tax1bp3	6736	0.189	-0.0074	No
35	Btg1	6813	0.185	-0.0067	No
36	Itgb4	6837	0.184	-0.0036	No
37	Sp1	7023	0.177	-0.0077	No
38	Slc3a2	7090	0.175	-0.0067	No
39	Btg2	7271	0.168	-0.0108	No
40	Zfp365	7400	0.162	-0.0127	No
41	Rnf19b	7435	0.161	-0.0107	No
42	Zmat3	7468	0.160	-0.0086	No
43	Ercc5	7485	0.160	-0.0058	No
44	App	7564	0.157	-0.0058	No
45	Vwa5a	7839	0.147	-0.0143	No
46	Sertad3	7850	0.147	-0.0115	No
47	Mapkapk3	7914	0.144	-0.0111	No
48	Klf4	7921	0.143	-0.0083	No
49	Aen	7951	0.142	-0.0064	No
50	Slc7a11	7967	0.141	-0.0040	No
51	Hspa4l	8008	0.140	-0.0027	No
52	Hmox1	8175	0.132	-0.0069	No
53	Ninj1	8738	0.110	-0.0285	No
54	Ptpn14	8750	0.109	-0.0266	No
55	Mxd4	8904	0.105	-0.0309	No
56	Fas	9000	0.102	-0.0327	No
57	Mdm2	9209	0.094	-0.0396	No
58	Ctsf	9582	0.081	-0.0537	No
59	Atf3	9711	0.077	-0.0575	No
60	Acvr1b	9745	0.076	-0.0572	No
61	Vdr	9997	0.066	-0.0665	No
62	Kif13b	10061	0.064	-0.0678	No
63	Mknk2	10112	0.062	-0.0686	No
64	Ddb2	10154	0.061	-0.0691	No
65	Xpc	10196	0.059	-0.0695	No
66	Traf4	10211	0.058	-0.0689	No
67	Irag2	10244	0.057	-0.0690	No
68	Slc35d1	10280	0.056	-0.0693	No
69	Sat1	10420	0.051	-0.0741	No
70	Hdac3	10470	0.049	-0.0751	No
71	Dram1	10570	0.045	-0.0784	No
72	Ralgds	10889	0.033	-0.0912	No
73	Nudt15	10949	0.031	-0.0931	No
74	Rrad	11014	0.029	-0.0952	No
75	Zbtb16	11110	0.026	-0.0987	No
76	Rb1	11120	0.026	-0.0985	No
77	Trib3	11216	0.023	-0.1021	No
78	Mxd1	11268	0.022	-0.1037	No
79	Wwp1	11286	0.022	-0.1040	No
80	Elp1	11287	0.022	-0.1035	No
81	Trafd1	11323	0.020	-0.1046	No
82	Fam162a	11358	0.019	-0.1056	No
83	Procr	11609	0.011	-0.1161	No
84	Plk3	11703	0.008	-0.1199	No
85	Retsat	11732	0.007	-0.1209	No
86	Sesn1	12205	-0.002	-0.1410	No
87	Prmt2	12424	-0.008	-0.1502	No
88	Fuca1	12471	-0.010	-0.1519	No
89	Prkab1	12557	-0.013	-0.1552	No
90	Gls2	12887	-0.025	-0.1687	No
91	Zfp36l1	13168	-0.034	-0.1800	No
92	Steap3	13193	-0.035	-0.1802	No
93	Dgka	13710	-0.052	-0.2011	No
94	Sdc1	13717	-0.053	-0.2002	No
95	Ppp1r15a	13845	-0.057	-0.2044	No
96	Tpd52l1	13929	-0.060	-0.2066	No
97	Tm7sf3	14174	-0.070	-0.2155	No
98	Ddit3	14240	-0.072	-0.2168	No
99	Cd81	14752	-0.090	-0.2366	No
100	Cyfip2	14823	-0.092	-0.2376	No
101	Eps8l2	14923	-0.095	-0.2398	No
102	Ccnk	15006	-0.099	-0.2411	No
103	Rad9a	15057	-0.101	-0.2411	No
104	Ddit4	15128	-0.103	-0.2419	No
105	Rchy1	15363	-0.112	-0.2494	No
106	Clca2	15536	-0.118	-0.2542	No
107	Tnni1	15728	-0.125	-0.2596	No
108	Ctsd	15897	-0.133	-0.2639	No
109	Rad51c	16026	-0.138	-0.2664	No
110	St14	16087	-0.140	-0.2660	No
111	Ier3	16200	-0.144	-0.2676	No
112	Ptpre	16216	-0.145	-0.2651	No
113	Notch1	16258	-0.147	-0.2637	No
114	Dcxr	16360	-0.151	-0.2648	No
115	Rap2b	16388	-0.152	-0.2626	No
116	Alox8	16538	-0.158	-0.2656	No
117	Ei24	16555	-0.158	-0.2628	No
118	Ier5	16827	-0.168	-0.2708	No
119	Cgrrf1	16962	-0.173	-0.2728	Yes
120	Def6	16968	-0.173	-0.2692	Yes
121	Phlda3	16977	-0.173	-0.2658	Yes
122	Ppm1d	16992	-0.174	-0.2626	Yes
123	Abat	17080	-0.177	-0.2625	Yes
124	Casp1	17123	-0.178	-0.2605	Yes
125	Slc19a2	17128	-0.178	-0.2568	Yes
126	Pmm1	17297	-0.185	-0.2599	Yes
127	Abhd4	17328	-0.186	-0.2572	Yes
128	Bax	17329	-0.187	-0.2531	Yes
129	Trp53	17404	-0.190	-0.2522	Yes
130	Cdkn2aip	17449	-0.191	-0.2499	Yes
131	Nol8	17488	-0.193	-0.2474	Yes
132	Cdh13	17504	-0.194	-0.2438	Yes
133	Ccng1	17677	-0.201	-0.2468	Yes
134	Pom121	17798	-0.206	-0.2475	Yes
135	Rhbdf2	17870	-0.209	-0.2460	Yes
136	Hbegf	18004	-0.215	-0.2470	Yes
137	F2r	18208	-0.221	-0.2509	Yes
138	Plxnb2	18297	-0.225	-0.2498	Yes
139	Klk8	18307	-0.225	-0.2453	Yes
140	Tap1	18516	-0.234	-0.2491	Yes
141	Pitpnc1	18840	-0.252	-0.2574	Yes
142	Tcn2	19122	-0.267	-0.2636	Yes
143	Gadd45a	19183	-0.269	-0.2604	Yes
144	S100a10	19260	-0.272	-0.2577	Yes
145	H2aj	19262	-0.272	-0.2519	Yes
146	Tprkb	19314	-0.275	-0.2481	Yes
147	Tsc22d1	19482	-0.284	-0.2491	Yes
148	Rxra	19561	-0.285	-0.2463	Yes
149	Coq8a	19597	-0.287	-0.2415	Yes
150	Sfn	19767	-0.298	-0.2423	Yes
151	Cdk5r1	19913	-0.307	-0.2418	Yes
152	Ankra2	19930	-0.308	-0.2359	Yes
153	Iscu	20256	-0.323	-0.2428	Yes
154	Pcna	20360	-0.328	-0.2401	Yes
155	Epha2	20469	-0.335	-0.2374	Yes
156	Fgf13	20562	-0.341	-0.2340	Yes
157	Ndrg1	20646	-0.346	-0.2300	Yes
158	Triap1	20649	-0.346	-0.2226	Yes
159	Pvt1	20704	-0.350	-0.2174	Yes
160	Tnfsf9	20731	-0.352	-0.2109	Yes
161	Cdkn1a	20892	-0.363	-0.2098	Yes
162	Tgfb1	21043	-0.373	-0.2082	Yes
163	Ccnd2	21087	-0.376	-0.2019	Yes
164	Pidd1	21198	-0.385	-0.1982	Yes
165	Wrap73	21339	-0.395	-0.1957	Yes
166	Cebpa	21402	-0.401	-0.1896	Yes
167	Hras	21530	-0.412	-0.1861	Yes
168	Sec61a1	21618	-0.420	-0.1808	Yes
169	Rps27l	21687	-0.423	-0.1745	Yes
170	Rpl18	21926	-0.445	-0.1750	Yes
171	Ada	22034	-0.455	-0.1698	Yes
172	Pdgfa	22063	-0.458	-0.1611	Yes
173	S100a4	22110	-0.463	-0.1530	Yes
174	Rack1	22127	-0.465	-0.1436	Yes
175	Rgs16	22145	-0.467	-0.1343	Yes
176	Bak1	22226	-0.475	-0.1274	Yes
177	Dnttip2	22295	-0.484	-0.1198	Yes
178	Irak1	22426	-0.495	-0.1147	Yes
179	Ifi30	22475	-0.501	-0.1059	Yes
180	Rps12	22523	-0.509	-0.0969	Yes
181	Nupr1	22533	-0.510	-0.0863	Yes
182	Rpl36	23150	-0.623	-0.0991	Yes
183	Jag2	23164	-0.629	-0.0860	Yes
184	Rrp8	23173	-0.632	-0.0727	Yes
185	Socs1	23187	-0.635	-0.0595	Yes
186	Gm2a	23246	-0.654	-0.0478	Yes
187	Ccnd3	23283	-0.667	-0.0350	Yes
188	Hint1	23372	-0.703	-0.0235	Yes
189	Vamp8	23416	-0.727	-0.0096	Yes
190	Sphk1	23552	-0.854	0.0031	Yes