| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group4.GMP.mono_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 3 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.31831318 |
| Normalized Enrichment Score (NES) | -1.3458605 |
| Nominal p-value | 0.18163672 |
| FDR q-value | 0.30601877 |
| FWER p-Value | 0.712 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tm7sf2 | 202 | 0.808 | 0.0085 | No |
| 2 | Ccnf | 849 | 0.571 | -0.0070 | No |
| 3 | Sytl2 | 1301 | 0.516 | -0.0153 | No |
| 4 | Cth | 1320 | 0.510 | -0.0052 | No |
| 5 | Gla | 1428 | 0.495 | 0.0007 | No |
| 6 | Bhlhe40 | 1657 | 0.462 | 0.0007 | No |
| 7 | Itgb2 | 1855 | 0.439 | 0.0016 | No |
| 8 | Cyp51 | 2201 | 0.412 | -0.0044 | No |
| 9 | Edem1 | 2594 | 0.386 | -0.0129 | No |
| 10 | Gpi1 | 2644 | 0.382 | -0.0069 | No |
| 11 | Rrp9 | 2973 | 0.365 | -0.0132 | No |
| 12 | Fdxr | 3012 | 0.362 | -0.0071 | No |
| 13 | Xbp1 | 3134 | 0.355 | -0.0048 | No |
| 14 | Ero1a | 3324 | 0.345 | -0.0055 | No |
| 15 | Stard4 | 3356 | 0.343 | 0.0004 | No |
| 16 | Idh1 | 3472 | 0.335 | 0.0026 | No |
| 17 | Hmgcr | 4022 | 0.302 | -0.0144 | No |
| 18 | Hspa4 | 4049 | 0.301 | -0.0091 | No |
| 19 | Bub1 | 4087 | 0.298 | -0.0044 | No |
| 20 | Actr2 | 4225 | 0.292 | -0.0041 | No |
| 21 | Aurka | 4280 | 0.288 | -0.0003 | No |
| 22 | Add3 | 4376 | 0.282 | 0.0016 | No |
| 23 | Plk1 | 4416 | 0.280 | 0.0059 | No |
| 24 | Gsr | 4461 | 0.278 | 0.0099 | No |
| 25 | Gga2 | 4468 | 0.278 | 0.0156 | No |
| 26 | Ufm1 | 4567 | 0.272 | 0.0172 | No |
| 27 | Canx | 4660 | 0.267 | 0.0189 | No |
| 28 | Pgm1 | 4869 | 0.257 | 0.0155 | No |
| 29 | Rdh11 | 5117 | 0.245 | 0.0101 | No |
| 30 | Etf1 | 5209 | 0.240 | 0.0113 | No |
| 31 | Sla | 5244 | 0.238 | 0.0149 | No |
| 32 | Actr3 | 5252 | 0.238 | 0.0197 | No |
| 33 | Nup205 | 5706 | 0.222 | 0.0050 | No |
| 34 | Hk2 | 5720 | 0.222 | 0.0092 | No |
| 35 | Hmbs | 5990 | 0.213 | 0.0022 | No |
| 36 | Idi1 | 6426 | 0.197 | -0.0122 | No |
| 37 | Hsp90b1 | 6454 | 0.196 | -0.0092 | No |
| 38 | Serp1 | 6507 | 0.194 | -0.0073 | No |
| 39 | Psme3 | 6801 | 0.186 | -0.0158 | No |
| 40 | Nfyc | 6815 | 0.185 | -0.0125 | No |
| 41 | Lta4h | 6816 | 0.185 | -0.0085 | No |
| 42 | Acly | 6924 | 0.180 | -0.0093 | No |
| 43 | Uso1 | 7088 | 0.175 | -0.0125 | No |
| 44 | Btg2 | 7271 | 0.168 | -0.0167 | No |
| 45 | Nufip1 | 7288 | 0.167 | -0.0139 | No |
| 46 | Sc5d | 7296 | 0.166 | -0.0107 | No |
| 47 | Igfbp5 | 7545 | 0.158 | -0.0179 | No |
| 48 | Rab1a | 7552 | 0.157 | -0.0148 | No |
| 49 | Gsk3b | 7720 | 0.151 | -0.0188 | No |
| 50 | Atp2a2 | 7751 | 0.150 | -0.0168 | No |
| 51 | Mcm4 | 7793 | 0.148 | -0.0155 | No |
| 52 | Ddx39a | 7796 | 0.148 | -0.0124 | No |
| 53 | Hspa9 | 7902 | 0.145 | -0.0138 | No |
| 54 | Slc7a11 | 7967 | 0.141 | -0.0136 | No |
| 55 | Ak4 | 8026 | 0.139 | -0.0131 | No |
| 56 | Gtf2h1 | 8227 | 0.130 | -0.0189 | No |
| 57 | Calr | 8332 | 0.127 | -0.0206 | No |
| 58 | Sqle | 8415 | 0.123 | -0.0215 | No |
| 59 | Dhcr24 | 8437 | 0.122 | -0.0198 | No |
| 60 | Fgl2 | 9434 | 0.087 | -0.0605 | No |
| 61 | Ssr1 | 9499 | 0.084 | -0.0614 | No |
| 62 | Hspd1 | 9567 | 0.082 | -0.0625 | No |
| 63 | G6pdx | 9645 | 0.080 | -0.0641 | No |
| 64 | Tbk1 | 9647 | 0.079 | -0.0625 | No |
| 65 | Ykt6 | 9868 | 0.072 | -0.0704 | No |
| 66 | Slc2a3 | 10010 | 0.066 | -0.0750 | No |
| 67 | Me1 | 10069 | 0.064 | -0.0761 | No |
| 68 | Insig1 | 10205 | 0.059 | -0.0806 | No |
| 69 | Gbe1 | 10356 | 0.054 | -0.0859 | No |
| 70 | Hmgcs1 | 10371 | 0.053 | -0.0854 | No |
| 71 | Gmps | 10380 | 0.053 | -0.0846 | No |
| 72 | Slc2a1 | 10494 | 0.048 | -0.0884 | No |
| 73 | Rit1 | 10535 | 0.047 | -0.0891 | No |
| 74 | Pno1 | 10618 | 0.043 | -0.0917 | No |
| 75 | Elovl5 | 10641 | 0.043 | -0.0917 | No |
| 76 | Slc1a4 | 10644 | 0.042 | -0.0909 | No |
| 77 | Abcf2 | 10762 | 0.038 | -0.0951 | No |
| 78 | Psmc6 | 10834 | 0.035 | -0.0974 | No |
| 79 | Stip1 | 10853 | 0.035 | -0.0974 | No |
| 80 | Ube2d3 | 10955 | 0.031 | -0.1011 | No |
| 81 | Skap2 | 11050 | 0.028 | -0.1045 | No |
| 82 | Pgk1 | 11213 | 0.023 | -0.1109 | No |
| 83 | Trib3 | 11216 | 0.023 | -0.1105 | No |
| 84 | Rpn1 | 11273 | 0.022 | -0.1125 | No |
| 85 | Plod2 | 11368 | 0.019 | -0.1161 | No |
| 86 | Sqstm1 | 11763 | 0.005 | -0.1328 | No |
| 87 | Cyb5b | 11805 | 0.004 | -0.1344 | No |
| 88 | P4ha1 | 12268 | -0.003 | -0.1541 | No |
| 89 | Ifrd1 | 12373 | -0.007 | -0.1584 | No |
| 90 | Immt | 12382 | -0.007 | -0.1586 | No |
| 91 | Pitpnb | 12548 | -0.012 | -0.1654 | No |
| 92 | Cd9 | 12962 | -0.027 | -0.1824 | No |
| 93 | Eno1b | 13014 | -0.029 | -0.1840 | No |
| 94 | Aldoa | 13091 | -0.031 | -0.1866 | No |
| 95 | Wars1 | 13462 | -0.045 | -0.2014 | No |
| 96 | Txnrd1 | 13715 | -0.053 | -0.2111 | No |
| 97 | M6pr | 13723 | -0.053 | -0.2102 | No |
| 98 | Ldlr | 13808 | -0.056 | -0.2126 | No |
| 99 | Mthfd2 | 13820 | -0.057 | -0.2119 | No |
| 100 | Ppp1r15a | 13845 | -0.057 | -0.2117 | No |
| 101 | Psmd14 | 14069 | -0.065 | -0.2198 | No |
| 102 | Nampt | 14150 | -0.068 | -0.2218 | No |
| 103 | Ppia | 14233 | -0.072 | -0.2238 | No |
| 104 | Hspa5 | 14235 | -0.072 | -0.2223 | No |
| 105 | Ddit3 | 14240 | -0.072 | -0.2210 | No |
| 106 | Mcm2 | 14588 | -0.085 | -0.2340 | No |
| 107 | Srd5a1 | 14648 | -0.086 | -0.2347 | No |
| 108 | Serpinh1 | 14890 | -0.094 | -0.2430 | No |
| 109 | Adipor2 | 14900 | -0.095 | -0.2413 | No |
| 110 | Ddit4 | 15128 | -0.103 | -0.2488 | No |
| 111 | Got1 | 15331 | -0.111 | -0.2551 | No |
| 112 | Lgmn | 15362 | -0.112 | -0.2540 | No |
| 113 | Rrm2 | 15507 | -0.117 | -0.2577 | No |
| 114 | Ctsc | 15551 | -0.118 | -0.2570 | No |
| 115 | Cdc25a | 15776 | -0.127 | -0.2639 | No |
| 116 | Rpa1 | 15896 | -0.133 | -0.2661 | No |
| 117 | Map2k3 | 16118 | -0.141 | -0.2726 | No |
| 118 | Cct6a | 16353 | -0.151 | -0.2794 | No |
| 119 | Slc7a5 | 16511 | -0.157 | -0.2828 | No |
| 120 | Dhfr | 16635 | -0.161 | -0.2846 | No |
| 121 | Polr3g | 16871 | -0.169 | -0.2910 | No |
| 122 | Niban1 | 16914 | -0.171 | -0.2892 | No |
| 123 | Sec11a | 17059 | -0.176 | -0.2916 | No |
| 124 | Psat1 | 17116 | -0.178 | -0.2902 | No |
| 125 | Psmc4 | 17195 | -0.181 | -0.2897 | No |
| 126 | Phgdh | 17303 | -0.185 | -0.2904 | No |
| 127 | Slc6a6 | 17391 | -0.189 | -0.2901 | No |
| 128 | Vldlr | 17401 | -0.190 | -0.2864 | No |
| 129 | Pdk1 | 17500 | -0.194 | -0.2865 | No |
| 130 | Ccng1 | 17677 | -0.201 | -0.2898 | No |
| 131 | Tcea1 | 17683 | -0.201 | -0.2857 | No |
| 132 | Nfil3 | 18397 | -0.230 | -0.3113 | No |
| 133 | Cfp | 18531 | -0.235 | -0.3120 | No |
| 134 | Glrx | 18620 | -0.239 | -0.3107 | No |
| 135 | Sord | 18734 | -0.245 | -0.3103 | No |
| 136 | Tpi1 | 18923 | -0.256 | -0.3129 | Yes |
| 137 | Nmt1 | 18957 | -0.258 | -0.3088 | Yes |
| 138 | Slc1a5 | 18962 | -0.258 | -0.3035 | Yes |
| 139 | Elovl6 | 18986 | -0.260 | -0.2990 | Yes |
| 140 | Pfkl | 19023 | -0.262 | -0.2950 | Yes |
| 141 | Dapp1 | 19227 | -0.271 | -0.2979 | Yes |
| 142 | Slc37a4 | 19313 | -0.275 | -0.2957 | Yes |
| 143 | Uchl5 | 19626 | -0.289 | -0.3029 | Yes |
| 144 | Tuba4a | 19643 | -0.291 | -0.2974 | Yes |
| 145 | Gclc | 19653 | -0.291 | -0.2916 | Yes |
| 146 | Ung | 19675 | -0.292 | -0.2863 | Yes |
| 147 | Psma4 | 19756 | -0.298 | -0.2834 | Yes |
| 148 | Qdpr | 19790 | -0.299 | -0.2785 | Yes |
| 149 | Tmem97 | 20156 | -0.317 | -0.2874 | Yes |
| 150 | Mthfd2l | 20354 | -0.328 | -0.2888 | Yes |
| 151 | Acsl3 | 20394 | -0.330 | -0.2835 | Yes |
| 152 | Coro1a | 20520 | -0.338 | -0.2817 | Yes |
| 153 | Tomm40 | 20559 | -0.341 | -0.2761 | Yes |
| 154 | Psma3 | 20585 | -0.342 | -0.2699 | Yes |
| 155 | Cops5 | 20609 | -0.343 | -0.2636 | Yes |
| 156 | Dhcr7 | 20720 | -0.351 | -0.2609 | Yes |
| 157 | Tes | 20721 | -0.351 | -0.2534 | Yes |
| 158 | Cdkn1a | 20892 | -0.363 | -0.2530 | Yes |
| 159 | Eef1e1 | 20987 | -0.370 | -0.2492 | Yes |
| 160 | Tfrc | 21073 | -0.375 | -0.2448 | Yes |
| 161 | Prdx1 | 21135 | -0.381 | -0.2394 | Yes |
| 162 | Egln3 | 21186 | -0.384 | -0.2334 | Yes |
| 163 | Pik3r3 | 21195 | -0.385 | -0.2256 | Yes |
| 164 | Psmd13 | 21259 | -0.390 | -0.2200 | Yes |
| 165 | Nfkbib | 21264 | -0.390 | -0.2119 | Yes |
| 166 | Ppa1 | 21331 | -0.395 | -0.2064 | Yes |
| 167 | Psmc2 | 21437 | -0.404 | -0.2023 | Yes |
| 168 | Ebp | 21570 | -0.416 | -0.1991 | Yes |
| 169 | Fkbp2 | 21612 | -0.419 | -0.1920 | Yes |
| 170 | Shmt2 | 21783 | -0.429 | -0.1901 | Yes |
| 171 | Acaca | 21896 | -0.441 | -0.1856 | Yes |
| 172 | Tubg1 | 22032 | -0.455 | -0.1817 | Yes |
| 173 | Atp6v1d | 22113 | -0.463 | -0.1753 | Yes |
| 174 | Psmb5 | 22134 | -0.465 | -0.1663 | Yes |
| 175 | Fads1 | 22159 | -0.469 | -0.1574 | Yes |
| 176 | Arpc5l | 22259 | -0.481 | -0.1514 | Yes |
| 177 | Sdf2l1 | 22346 | -0.488 | -0.1447 | Yes |
| 178 | Ifi30 | 22475 | -0.501 | -0.1396 | Yes |
| 179 | Nupr1 | 22533 | -0.510 | -0.1312 | Yes |
| 180 | Psmd12 | 22534 | -0.510 | -0.1204 | Yes |
| 181 | Bcat1 | 22543 | -0.511 | -0.1099 | Yes |
| 182 | Mllt11 | 22666 | -0.527 | -0.1040 | Yes |
| 183 | Ldha | 22704 | -0.532 | -0.0943 | Yes |
| 184 | Psph | 22768 | -0.541 | -0.0855 | Yes |
| 185 | Pdap1 | 22933 | -0.573 | -0.0803 | Yes |
| 186 | Cxcr4 | 22937 | -0.574 | -0.0683 | Yes |
| 187 | Fads2 | 23016 | -0.592 | -0.0591 | Yes |
| 188 | Psmg1 | 23116 | -0.617 | -0.0503 | Yes |
| 189 | Hspe1 | 23141 | -0.621 | -0.0381 | Yes |
| 190 | Cacybp | 23171 | -0.632 | -0.0260 | Yes |
| 191 | Eif2s2 | 23207 | -0.640 | -0.0139 | Yes |
| 192 | Asns | 23402 | -0.716 | -0.0070 | Yes |
| 193 | Pnp | 23475 | -0.775 | 0.0064 | Yes |

