| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group4.GMP.mono_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.305544 |
| Normalized Enrichment Score (NES) | 1.2972454 |
| Nominal p-value | 0.28373015 |
| FDR q-value | 0.9285578 |
| FWER p-Value | 0.79 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdkn2c | 387 | 0.713 | 0.0003 | Yes |
| 2 | Cenpf | 539 | 0.648 | 0.0092 | Yes |
| 3 | Cdc25b | 662 | 0.615 | 0.0186 | Yes |
| 4 | Incenp | 776 | 0.588 | 0.0277 | Yes |
| 5 | Ccnf | 849 | 0.571 | 0.0381 | Yes |
| 6 | Hnrnpu | 866 | 0.569 | 0.0509 | Yes |
| 7 | Espl1 | 881 | 0.568 | 0.0637 | Yes |
| 8 | Racgap1 | 1039 | 0.547 | 0.0699 | Yes |
| 9 | Hnrnpd | 1298 | 0.517 | 0.0711 | Yes |
| 10 | Kif2c | 1327 | 0.509 | 0.0819 | Yes |
| 11 | Kif11 | 1435 | 0.494 | 0.0891 | Yes |
| 12 | Kpnb1 | 1478 | 0.487 | 0.0988 | Yes |
| 13 | Kif23 | 1572 | 0.473 | 0.1060 | Yes |
| 14 | Xpo1 | 1637 | 0.464 | 0.1143 | Yes |
| 15 | Upf1 | 1699 | 0.458 | 0.1225 | Yes |
| 16 | Prc1 | 1766 | 0.449 | 0.1303 | Yes |
| 17 | Rad21 | 1800 | 0.446 | 0.1394 | Yes |
| 18 | Numa1 | 2156 | 0.415 | 0.1341 | Yes |
| 19 | Sfpq | 2464 | 0.393 | 0.1303 | Yes |
| 20 | Kif22 | 2622 | 0.384 | 0.1327 | Yes |
| 21 | Nek2 | 2633 | 0.383 | 0.1413 | Yes |
| 22 | Tent4a | 2642 | 0.382 | 0.1500 | Yes |
| 23 | Ttk | 2742 | 0.379 | 0.1547 | Yes |
| 24 | Odc1 | 2746 | 0.378 | 0.1635 | Yes |
| 25 | Cenpe | 2782 | 0.375 | 0.1709 | Yes |
| 26 | Top2a | 2856 | 0.370 | 0.1765 | Yes |
| 27 | H2bc12 | 3183 | 0.352 | 0.1709 | Yes |
| 28 | Tfdp1 | 3233 | 0.350 | 0.1771 | Yes |
| 29 | Hmmr | 3279 | 0.347 | 0.1834 | Yes |
| 30 | Odf2 | 3281 | 0.347 | 0.1916 | Yes |
| 31 | Cdkn1b | 3396 | 0.340 | 0.1947 | Yes |
| 32 | Srsf1 | 3435 | 0.338 | 0.2011 | Yes |
| 33 | Cdk1 | 3665 | 0.321 | 0.1989 | Yes |
| 34 | Ccnb2 | 3855 | 0.311 | 0.1982 | Yes |
| 35 | Kif4 | 4021 | 0.302 | 0.1983 | Yes |
| 36 | Ndc80 | 4062 | 0.300 | 0.2037 | Yes |
| 37 | Smc1a | 4072 | 0.299 | 0.2104 | Yes |
| 38 | Lmnb1 | 4073 | 0.299 | 0.2175 | Yes |
| 39 | Bub1 | 4087 | 0.298 | 0.2239 | Yes |
| 40 | Nup98 | 4099 | 0.297 | 0.2305 | Yes |
| 41 | Egf | 4237 | 0.291 | 0.2315 | Yes |
| 42 | Aurka | 4280 | 0.288 | 0.2365 | Yes |
| 43 | Dr1 | 4295 | 0.287 | 0.2427 | Yes |
| 44 | Mcm5 | 4355 | 0.284 | 0.2469 | Yes |
| 45 | Kif20b | 4375 | 0.282 | 0.2528 | Yes |
| 46 | Mki67 | 4407 | 0.281 | 0.2581 | Yes |
| 47 | Mapk14 | 4408 | 0.281 | 0.2647 | Yes |
| 48 | Plk1 | 4416 | 0.280 | 0.2711 | Yes |
| 49 | Chaf1a | 4505 | 0.276 | 0.2738 | Yes |
| 50 | Notch2 | 4537 | 0.274 | 0.2790 | Yes |
| 51 | Lbr | 4636 | 0.268 | 0.2811 | Yes |
| 52 | Map3k20 | 4758 | 0.262 | 0.2822 | Yes |
| 53 | Efna5 | 5176 | 0.242 | 0.2701 | Yes |
| 54 | Kif15 | 5314 | 0.235 | 0.2698 | Yes |
| 55 | Tacc3 | 5317 | 0.235 | 0.2753 | Yes |
| 56 | G3bp1 | 5565 | 0.229 | 0.2701 | Yes |
| 57 | Bard1 | 5591 | 0.228 | 0.2745 | Yes |
| 58 | Ewsr1 | 5625 | 0.226 | 0.2784 | Yes |
| 59 | Tpx2 | 5641 | 0.226 | 0.2831 | Yes |
| 60 | Syncrip | 5656 | 0.225 | 0.2878 | Yes |
| 61 | Tnpo2 | 5675 | 0.224 | 0.2923 | Yes |
| 62 | Ube2s | 5731 | 0.221 | 0.2952 | Yes |
| 63 | Cenpa | 5759 | 0.219 | 0.2993 | Yes |
| 64 | Uck2 | 5785 | 0.218 | 0.3033 | Yes |
| 65 | Slc12a2 | 5938 | 0.215 | 0.3019 | Yes |
| 66 | Aurkb | 6081 | 0.210 | 0.3008 | Yes |
| 67 | Ilf3 | 6309 | 0.202 | 0.2959 | Yes |
| 68 | Cdc7 | 6310 | 0.202 | 0.3007 | Yes |
| 69 | Pole | 6330 | 0.201 | 0.3046 | Yes |
| 70 | Fancc | 6710 | 0.190 | 0.2929 | Yes |
| 71 | Ss18 | 6735 | 0.189 | 0.2964 | Yes |
| 72 | Smarcc1 | 6741 | 0.189 | 0.3006 | Yes |
| 73 | Tmpo | 6789 | 0.187 | 0.3031 | Yes |
| 74 | Nsd2 | 6904 | 0.181 | 0.3025 | Yes |
| 75 | Polq | 6959 | 0.179 | 0.3044 | Yes |
| 76 | Orc5 | 7045 | 0.177 | 0.3050 | Yes |
| 77 | Pds5b | 7221 | 0.170 | 0.3015 | Yes |
| 78 | Rbl1 | 7231 | 0.169 | 0.3051 | Yes |
| 79 | Stil | 7347 | 0.165 | 0.3041 | Yes |
| 80 | Troap | 7404 | 0.162 | 0.3055 | Yes |
| 81 | Mybl2 | 7672 | 0.153 | 0.2978 | No |
| 82 | Ddx39a | 7796 | 0.148 | 0.2960 | No |
| 83 | Ccna2 | 7816 | 0.147 | 0.2987 | No |
| 84 | Cul3 | 7961 | 0.142 | 0.2959 | No |
| 85 | E2f3 | 7996 | 0.140 | 0.2978 | No |
| 86 | Tra2b | 7998 | 0.140 | 0.3010 | No |
| 87 | Hmga1b | 8041 | 0.138 | 0.3025 | No |
| 88 | Plk4 | 8184 | 0.132 | 0.2996 | No |
| 89 | Knl1 | 8385 | 0.124 | 0.2940 | No |
| 90 | Pafah1b1 | 8392 | 0.124 | 0.2967 | No |
| 91 | Sqle | 8415 | 0.123 | 0.2986 | No |
| 92 | Cdc45 | 8444 | 0.122 | 0.3003 | No |
| 93 | Prim2 | 8494 | 0.120 | 0.3011 | No |
| 94 | Prpf4b | 8568 | 0.117 | 0.3007 | No |
| 95 | Amd1 | 8574 | 0.117 | 0.3033 | No |
| 96 | Cks2 | 8615 | 0.115 | 0.3043 | No |
| 97 | Hspa8 | 8739 | 0.110 | 0.3016 | No |
| 98 | Suv39h1 | 8889 | 0.106 | 0.2978 | No |
| 99 | Foxn3 | 8973 | 0.103 | 0.2967 | No |
| 100 | Stag1 | 9196 | 0.095 | 0.2894 | No |
| 101 | Ythdc1 | 9216 | 0.094 | 0.2908 | No |
| 102 | Atrx | 9220 | 0.094 | 0.2929 | No |
| 103 | Cul4a | 9353 | 0.090 | 0.2894 | No |
| 104 | Dbf4 | 9525 | 0.083 | 0.2841 | No |
| 105 | Smad3 | 9665 | 0.079 | 0.2800 | No |
| 106 | Ctcf | 9758 | 0.075 | 0.2779 | No |
| 107 | Cul1 | 9761 | 0.075 | 0.2796 | No |
| 108 | Rad54l | 9777 | 0.075 | 0.2807 | No |
| 109 | Arid4a | 9888 | 0.071 | 0.2777 | No |
| 110 | Ccnt1 | 10102 | 0.062 | 0.2701 | No |
| 111 | Wrn | 10111 | 0.062 | 0.2712 | No |
| 112 | Brca2 | 10265 | 0.057 | 0.2660 | No |
| 113 | Hira | 10563 | 0.046 | 0.2544 | No |
| 114 | Nusap1 | 10580 | 0.045 | 0.2548 | No |
| 115 | Dtymk | 10627 | 0.043 | 0.2538 | No |
| 116 | Chmp1a | 10699 | 0.040 | 0.2518 | No |
| 117 | Mtf2 | 10749 | 0.038 | 0.2506 | No |
| 118 | Chek1 | 10797 | 0.037 | 0.2494 | No |
| 119 | Abl1 | 10871 | 0.034 | 0.2471 | No |
| 120 | Ccnd1 | 10919 | 0.032 | 0.2459 | No |
| 121 | Lig3 | 10922 | 0.032 | 0.2466 | No |
| 122 | Srsf10 | 10937 | 0.031 | 0.2467 | No |
| 123 | Rad23b | 11036 | 0.028 | 0.2432 | No |
| 124 | Cdc27 | 11071 | 0.027 | 0.2424 | No |
| 125 | Nup50 | 11208 | 0.023 | 0.2371 | No |
| 126 | Traip | 11390 | 0.018 | 0.2298 | No |
| 127 | Mcm6 | 11413 | 0.017 | 0.2293 | No |
| 128 | Mcm3 | 11488 | 0.015 | 0.2265 | No |
| 129 | Smc4 | 11585 | 0.012 | 0.2227 | No |
| 130 | Srsf2 | 11756 | 0.006 | 0.2155 | No |
| 131 | Gspt1 | 11809 | 0.004 | 0.2134 | No |
| 132 | Cdc6 | 11875 | 0.002 | 0.2107 | No |
| 133 | Hif1a | 11894 | 0.001 | 0.2099 | No |
| 134 | Pttg1 | 12403 | -0.007 | 0.1884 | No |
| 135 | Atf5 | 12533 | -0.012 | 0.1832 | No |
| 136 | Katna1 | 12546 | -0.012 | 0.1830 | No |
| 137 | Cdkn3 | 12657 | -0.016 | 0.1787 | No |
| 138 | Kif5b | 12755 | -0.019 | 0.1750 | No |
| 139 | Smc2 | 12760 | -0.019 | 0.1753 | No |
| 140 | Pola2 | 12779 | -0.020 | 0.1750 | No |
| 141 | Exo1 | 12988 | -0.028 | 0.1668 | No |
| 142 | Cul5 | 13054 | -0.030 | 0.1647 | No |
| 143 | Pbk | 13180 | -0.035 | 0.1602 | No |
| 144 | Slc38a1 | 13326 | -0.040 | 0.1550 | No |
| 145 | Mad2l1 | 13344 | -0.040 | 0.1552 | No |
| 146 | Mnat1 | 13503 | -0.046 | 0.1495 | No |
| 147 | H2az1 | 13912 | -0.060 | 0.1335 | No |
| 148 | Pml | 13954 | -0.061 | 0.1332 | No |
| 149 | Tle3 | 14009 | -0.063 | 0.1324 | No |
| 150 | Ncl | 14255 | -0.072 | 0.1237 | No |
| 151 | Ube2c | 14404 | -0.078 | 0.1192 | No |
| 152 | Nasp | 14477 | -0.081 | 0.1180 | No |
| 153 | Mcm2 | 14588 | -0.085 | 0.1153 | No |
| 154 | Ezh2 | 14621 | -0.085 | 0.1160 | No |
| 155 | Fbxo5 | 15155 | -0.105 | 0.0957 | No |
| 156 | Rasal2 | 15286 | -0.110 | 0.0928 | No |
| 157 | Top1 | 15335 | -0.111 | 0.0933 | No |
| 158 | Cdc25a | 15776 | -0.127 | 0.0776 | No |
| 159 | E2f1 | 16063 | -0.139 | 0.0686 | No |
| 160 | Rps6ka5 | 16068 | -0.139 | 0.0718 | No |
| 161 | Slc7a5 | 16511 | -0.157 | 0.0566 | No |
| 162 | Hmgb3 | 17148 | -0.179 | 0.0337 | No |
| 163 | Meis2 | 17273 | -0.184 | 0.0328 | No |
| 164 | E2f2 | 17311 | -0.186 | 0.0356 | No |
| 165 | H2az2 | 17369 | -0.188 | 0.0376 | No |
| 166 | Casp8ap2 | 17518 | -0.195 | 0.0359 | No |
| 167 | Kmt5a | 17606 | -0.198 | 0.0368 | No |
| 168 | Jpt1 | 17676 | -0.201 | 0.0386 | No |
| 169 | Sap30 | 17754 | -0.204 | 0.0402 | No |
| 170 | Hus1 | 17826 | -0.208 | 0.0421 | No |
| 171 | Bcl3 | 17956 | -0.213 | 0.0416 | No |
| 172 | Birc5 | 18263 | -0.223 | 0.0338 | No |
| 173 | H2ax | 18654 | -0.241 | 0.0229 | No |
| 174 | E2f4 | 19034 | -0.262 | 0.0129 | No |
| 175 | Nolc1 | 19157 | -0.268 | 0.0140 | No |
| 176 | Cdc20 | 19194 | -0.270 | 0.0189 | No |
| 177 | Slc7a1 | 19390 | -0.279 | 0.0172 | No |
| 178 | Meis1 | 19573 | -0.286 | 0.0161 | No |
| 179 | Stmn1 | 19611 | -0.288 | 0.0214 | No |
| 180 | Orc6 | 19997 | -0.310 | 0.0123 | No |
| 181 | Rpa2 | 20001 | -0.311 | 0.0195 | No |
| 182 | Dmd | 20139 | -0.316 | 0.0211 | No |
| 183 | Cbx1 | 20236 | -0.322 | 0.0246 | No |
| 184 | Bub3 | 20302 | -0.325 | 0.0295 | No |
| 185 | Prmt5 | 20798 | -0.356 | 0.0168 | No |
| 186 | Dkc1 | 20809 | -0.357 | 0.0249 | No |
| 187 | Tgfb1 | 21043 | -0.373 | 0.0237 | No |
| 188 | Marcks | 21244 | -0.389 | 0.0244 | No |
| 189 | Snrpd1 | 21606 | -0.419 | 0.0189 | No |
| 190 | Cdk4 | 21809 | -0.432 | 0.0205 | No |
| 191 | Cks1b | 22234 | -0.476 | 0.0136 | No |
| 192 | Pura | 22580 | -0.516 | 0.0111 | No |
| 193 | Myc | 23257 | -0.657 | -0.0022 | No |
| 194 | Gins2 | 23445 | -0.754 | 0.0076 | No |

