| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group4.GMP.mono_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.16400571 |
| Normalized Enrichment Score (NES) | 0.65703857 |
| Nominal p-value | 0.76954734 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Cdkn2c | 387 | 0.713 | -0.0006 | Yes |
| 2 | Cdc25b | 662 | 0.615 | 0.0015 | Yes |
| 3 | Espl1 | 881 | 0.568 | 0.0048 | Yes |
| 4 | Dlgap5 | 989 | 0.550 | 0.0126 | Yes |
| 5 | Racgap1 | 1039 | 0.547 | 0.0227 | Yes |
| 6 | Hnrnpd | 1298 | 0.517 | 0.0232 | Yes |
| 7 | Kif18b | 1303 | 0.516 | 0.0346 | Yes |
| 8 | Ncapd2 | 1325 | 0.509 | 0.0451 | Yes |
| 9 | Kif2c | 1327 | 0.509 | 0.0564 | Yes |
| 10 | Ipo7 | 1538 | 0.478 | 0.0581 | Yes |
| 11 | Xpo1 | 1637 | 0.464 | 0.0643 | Yes |
| 12 | Rad21 | 1800 | 0.446 | 0.0674 | Yes |
| 13 | Kif22 | 2622 | 0.384 | 0.0409 | Yes |
| 14 | Cit | 2762 | 0.377 | 0.0434 | Yes |
| 15 | Cenpe | 2782 | 0.375 | 0.0509 | Yes |
| 16 | Top2a | 2856 | 0.370 | 0.0561 | Yes |
| 17 | Spag5 | 2980 | 0.365 | 0.0590 | Yes |
| 18 | Hmmr | 3279 | 0.347 | 0.0541 | Yes |
| 19 | Cdkn1b | 3396 | 0.340 | 0.0567 | Yes |
| 20 | Depdc1a | 3417 | 0.339 | 0.0634 | Yes |
| 21 | Srsf1 | 3435 | 0.338 | 0.0703 | Yes |
| 22 | Nup107 | 3438 | 0.337 | 0.0777 | Yes |
| 23 | Bub1b | 3509 | 0.333 | 0.0822 | Yes |
| 24 | Cse1l | 3586 | 0.328 | 0.0862 | Yes |
| 25 | Cdk1 | 3665 | 0.321 | 0.0901 | Yes |
| 26 | Ccp110 | 3805 | 0.315 | 0.0912 | Yes |
| 27 | Ccnb2 | 3855 | 0.311 | 0.0961 | Yes |
| 28 | Cdca8 | 3908 | 0.308 | 0.1007 | Yes |
| 29 | Kif4 | 4021 | 0.302 | 0.1027 | Yes |
| 30 | Smc1a | 4072 | 0.299 | 0.1073 | Yes |
| 31 | Lmnb1 | 4073 | 0.299 | 0.1139 | Yes |
| 32 | Cdkn2a | 4089 | 0.298 | 0.1199 | Yes |
| 33 | Spc25 | 4146 | 0.295 | 0.1241 | Yes |
| 34 | Aurka | 4280 | 0.288 | 0.1249 | Yes |
| 35 | Mcm5 | 4355 | 0.284 | 0.1281 | Yes |
| 36 | Mki67 | 4407 | 0.281 | 0.1322 | Yes |
| 37 | Plk1 | 4416 | 0.280 | 0.1381 | Yes |
| 38 | Smc3 | 4444 | 0.279 | 0.1432 | Yes |
| 39 | Zw10 | 4629 | 0.269 | 0.1413 | Yes |
| 40 | Dnmt1 | 4631 | 0.269 | 0.1473 | Yes |
| 41 | Lbr | 4636 | 0.268 | 0.1531 | Yes |
| 42 | Pan2 | 4652 | 0.267 | 0.1585 | Yes |
| 43 | Melk | 4721 | 0.264 | 0.1615 | Yes |
| 44 | Atad2 | 4957 | 0.252 | 0.1571 | Yes |
| 45 | Brca1 | 4976 | 0.252 | 0.1619 | Yes |
| 46 | Wdr90 | 5058 | 0.248 | 0.1640 | Yes |
| 47 | Tacc3 | 5317 | 0.235 | 0.1582 | No |
| 48 | Bard1 | 5591 | 0.228 | 0.1517 | No |
| 49 | Syncrip | 5656 | 0.225 | 0.1540 | No |
| 50 | Nup205 | 5706 | 0.222 | 0.1568 | No |
| 51 | Ube2s | 5731 | 0.221 | 0.1608 | No |
| 52 | Wee1 | 5924 | 0.216 | 0.1574 | No |
| 53 | Aurkb | 6081 | 0.210 | 0.1554 | No |
| 54 | Brms1l | 6133 | 0.206 | 0.1579 | No |
| 55 | Ubr7 | 6142 | 0.206 | 0.1621 | No |
| 56 | Ilf3 | 6309 | 0.202 | 0.1595 | No |
| 57 | Pole | 6330 | 0.201 | 0.1632 | No |
| 58 | Diaph3 | 6656 | 0.192 | 0.1536 | No |
| 59 | Tmpo | 6789 | 0.187 | 0.1521 | No |
| 60 | Prkdc | 6873 | 0.182 | 0.1527 | No |
| 61 | Timeless | 7125 | 0.173 | 0.1458 | No |
| 62 | Dck | 7180 | 0.171 | 0.1474 | No |
| 63 | Pds5b | 7221 | 0.170 | 0.1494 | No |
| 64 | Rbbp7 | 7495 | 0.159 | 0.1413 | No |
| 65 | Mybl2 | 7672 | 0.153 | 0.1373 | No |
| 66 | Mcm4 | 7793 | 0.148 | 0.1355 | No |
| 67 | Ddx39a | 7796 | 0.148 | 0.1387 | No |
| 68 | Msh2 | 7924 | 0.143 | 0.1365 | No |
| 69 | Tra2b | 7998 | 0.140 | 0.1365 | No |
| 70 | Cdca3 | 8029 | 0.139 | 0.1383 | No |
| 71 | Hmga1b | 8041 | 0.138 | 0.1409 | No |
| 72 | Mre11a | 8157 | 0.133 | 0.1390 | No |
| 73 | Prps1 | 8168 | 0.133 | 0.1415 | No |
| 74 | Plk4 | 8184 | 0.132 | 0.1438 | No |
| 75 | Slbp | 8371 | 0.125 | 0.1387 | No |
| 76 | Ing3 | 8405 | 0.124 | 0.1400 | No |
| 77 | Cbx5 | 8411 | 0.123 | 0.1426 | No |
| 78 | Rfc1 | 8441 | 0.122 | 0.1441 | No |
| 79 | Chek2 | 8489 | 0.120 | 0.1448 | No |
| 80 | Prim2 | 8494 | 0.120 | 0.1473 | No |
| 81 | Cks2 | 8615 | 0.115 | 0.1447 | No |
| 82 | E2f8 | 8626 | 0.115 | 0.1469 | No |
| 83 | Anp32e | 8657 | 0.113 | 0.1481 | No |
| 84 | Suv39h1 | 8889 | 0.106 | 0.1406 | No |
| 85 | Stag1 | 9196 | 0.095 | 0.1297 | No |
| 86 | Mlh1 | 9424 | 0.087 | 0.1219 | No |
| 87 | Tubb5 | 9583 | 0.081 | 0.1170 | No |
| 88 | Eed | 9678 | 0.078 | 0.1147 | No |
| 89 | Ctcf | 9758 | 0.075 | 0.1131 | No |
| 90 | Brca2 | 10265 | 0.057 | 0.0927 | No |
| 91 | Ssrp1 | 10315 | 0.055 | 0.0919 | No |
| 92 | Lsm8 | 10789 | 0.037 | 0.0725 | No |
| 93 | Chek1 | 10797 | 0.037 | 0.0730 | No |
| 94 | Shmt1 | 10969 | 0.030 | 0.0664 | No |
| 95 | Xrcc6 | 11072 | 0.027 | 0.0626 | No |
| 96 | Ak2 | 11132 | 0.025 | 0.0607 | No |
| 97 | Hells | 11355 | 0.019 | 0.0516 | No |
| 98 | Tbrg4 | 11405 | 0.017 | 0.0499 | No |
| 99 | Mcm6 | 11413 | 0.017 | 0.0500 | No |
| 100 | Mcm3 | 11488 | 0.015 | 0.0472 | No |
| 101 | Tcf19 | 11559 | 0.013 | 0.0445 | No |
| 102 | Smc4 | 11585 | 0.012 | 0.0437 | No |
| 103 | Nap1l1 | 11614 | 0.011 | 0.0427 | No |
| 104 | Srsf2 | 11756 | 0.006 | 0.0368 | No |
| 105 | Nudt21 | 11760 | 0.006 | 0.0368 | No |
| 106 | Gspt1 | 11809 | 0.004 | 0.0349 | No |
| 107 | Pttg1 | 12403 | -0.007 | 0.0097 | No |
| 108 | Pnn | 12444 | -0.009 | 0.0082 | No |
| 109 | Smc6 | 12484 | -0.011 | 0.0068 | No |
| 110 | Tk1 | 12530 | -0.012 | 0.0051 | No |
| 111 | Cdkn3 | 12657 | -0.016 | 0.0001 | No |
| 112 | Nop56 | 12683 | -0.017 | -0.0006 | No |
| 113 | Ube2t | 12736 | -0.019 | -0.0024 | No |
| 114 | Mcm7 | 12745 | -0.019 | -0.0023 | No |
| 115 | Mms22l | 12764 | -0.020 | -0.0026 | No |
| 116 | Pola2 | 12779 | -0.020 | -0.0028 | No |
| 117 | Exosc8 | 12983 | -0.028 | -0.0108 | No |
| 118 | Mad2l1 | 13344 | -0.040 | -0.0253 | No |
| 119 | Mthfd2 | 13820 | -0.057 | -0.0443 | No |
| 120 | H2az1 | 13912 | -0.060 | -0.0468 | No |
| 121 | Pold1 | 14299 | -0.074 | -0.0616 | No |
| 122 | Nasp | 14477 | -0.081 | -0.0674 | No |
| 123 | Mcm2 | 14588 | -0.085 | -0.0702 | No |
| 124 | Ezh2 | 14621 | -0.085 | -0.0697 | No |
| 125 | Eif2s1 | 14841 | -0.093 | -0.0769 | No |
| 126 | Pole4 | 14878 | -0.094 | -0.0764 | No |
| 127 | Pold3 | 14987 | -0.098 | -0.0788 | No |
| 128 | Hmgb2 | 14992 | -0.099 | -0.0768 | No |
| 129 | Lig1 | 15033 | -0.100 | -0.0762 | No |
| 130 | Luc7l3 | 15100 | -0.102 | -0.0768 | No |
| 131 | Dscc1 | 15178 | -0.106 | -0.0777 | No |
| 132 | Psmc3ip | 15241 | -0.108 | -0.0779 | No |
| 133 | Rrm2 | 15507 | -0.117 | -0.0866 | No |
| 134 | Donson | 15581 | -0.119 | -0.0871 | No |
| 135 | Rpa3 | 15628 | -0.122 | -0.0863 | No |
| 136 | Ppp1r8 | 15687 | -0.124 | -0.0861 | No |
| 137 | Cdc25a | 15776 | -0.127 | -0.0870 | No |
| 138 | Rpa1 | 15896 | -0.133 | -0.0891 | No |
| 139 | Rad51c | 16026 | -0.138 | -0.0915 | No |
| 140 | Ccne1 | 16154 | -0.142 | -0.0938 | No |
| 141 | Rad51ap1 | 16181 | -0.143 | -0.0917 | No |
| 142 | Gins4 | 16280 | -0.148 | -0.0926 | No |
| 143 | Pms2 | 16416 | -0.153 | -0.0949 | No |
| 144 | Dek | 16442 | -0.154 | -0.0925 | No |
| 145 | Rad50 | 16477 | -0.156 | -0.0905 | No |
| 146 | Nup153 | 16562 | -0.158 | -0.0905 | No |
| 147 | Usp1 | 16569 | -0.159 | -0.0872 | No |
| 148 | Nbn | 16919 | -0.171 | -0.0983 | No |
| 149 | Psip1 | 16943 | -0.172 | -0.0954 | No |
| 150 | Ppm1d | 16992 | -0.174 | -0.0936 | No |
| 151 | Hmgb3 | 17148 | -0.179 | -0.0962 | No |
| 152 | Trp53 | 17404 | -0.190 | -0.1029 | No |
| 153 | Orc2 | 17528 | -0.195 | -0.1038 | No |
| 154 | Jpt1 | 17676 | -0.201 | -0.1055 | No |
| 155 | Hus1 | 17826 | -0.208 | -0.1073 | No |
| 156 | Birc5 | 18263 | -0.223 | -0.1209 | No |
| 157 | Trip13 | 18287 | -0.224 | -0.1168 | No |
| 158 | Paics | 18352 | -0.227 | -0.1145 | No |
| 159 | Rad1 | 18583 | -0.238 | -0.1190 | No |
| 160 | H2ax | 18654 | -0.241 | -0.1166 | No |
| 161 | Spc24 | 18722 | -0.244 | -0.1140 | No |
| 162 | Dclre1b | 18972 | -0.259 | -0.1189 | No |
| 163 | Gins3 | 18980 | -0.259 | -0.1134 | No |
| 164 | Cnot9 | 19071 | -0.264 | -0.1113 | No |
| 165 | Tipin | 19095 | -0.265 | -0.1064 | No |
| 166 | Rnaseh2a | 19129 | -0.267 | -0.1018 | No |
| 167 | Nolc1 | 19157 | -0.268 | -0.0970 | No |
| 168 | Cdc20 | 19194 | -0.270 | -0.0925 | No |
| 169 | Stmn1 | 19611 | -0.288 | -0.1038 | No |
| 170 | Ung | 19675 | -0.292 | -0.0999 | No |
| 171 | Dut | 19738 | -0.296 | -0.0960 | No |
| 172 | Phf5a | 19763 | -0.298 | -0.0903 | No |
| 173 | Rfc2 | 19766 | -0.298 | -0.0837 | No |
| 174 | Cenpm | 19897 | -0.306 | -0.0825 | No |
| 175 | Asf1b | 19903 | -0.306 | -0.0758 | No |
| 176 | Gins1 | 19923 | -0.307 | -0.0698 | No |
| 177 | Orc6 | 19997 | -0.310 | -0.0660 | No |
| 178 | Rpa2 | 20001 | -0.311 | -0.0591 | No |
| 179 | Pcna | 20360 | -0.328 | -0.0671 | No |
| 180 | Rfc3 | 20686 | -0.348 | -0.0732 | No |
| 181 | Lyar | 20837 | -0.359 | -0.0716 | No |
| 182 | Cdkn1a | 20892 | -0.363 | -0.0658 | No |
| 183 | Ranbp1 | 20994 | -0.370 | -0.0618 | No |
| 184 | Tfrc | 21073 | -0.375 | -0.0568 | No |
| 185 | Mxd3 | 21266 | -0.390 | -0.0562 | No |
| 186 | Pop7 | 21715 | -0.425 | -0.0659 | No |
| 187 | Cdk4 | 21809 | -0.432 | -0.0602 | No |
| 188 | Tubg1 | 22032 | -0.455 | -0.0595 | No |
| 189 | Cks1b | 22234 | -0.476 | -0.0574 | No |
| 190 | Pold2 | 22246 | -0.478 | -0.0472 | No |
| 191 | Asf1a | 22307 | -0.485 | -0.0389 | No |
| 192 | Snrpb | 22317 | -0.486 | -0.0285 | No |
| 193 | Ran | 22328 | -0.487 | -0.0180 | No |
| 194 | Pa2g4 | 22350 | -0.488 | -0.0080 | No |
| 195 | Prdx4 | 23153 | -0.624 | -0.0283 | No |
| 196 | Myc | 23257 | -0.657 | -0.0180 | No |
| 197 | Dctpp1 | 23305 | -0.673 | -0.0050 | No |
| 198 | Nme1 | 23537 | -0.831 | 0.0037 | No |

