Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group1_versus_Group3.GMP.mono_Pheno.cls #Group1_versus_Group3_repos
Phenotype	GMP.mono_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.27983823
Normalized Enrichment Score (NES)	-1.282267
Nominal p-value	0.15062761
FDR q-value	0.6045744
FWER p-Value	0.798

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Cltc	1252	0.436	-0.0334	No
2	Trib3	1491	0.409	-0.0250	No
3	Plcb1	2185	0.353	-0.0384	No
4	Pikfyve	2459	0.329	-0.0351	No
5	Cdk1	2492	0.326	-0.0216	No
6	Tiam1	2556	0.321	-0.0097	No
7	Cdkn1b	2626	0.318	0.0018	No
8	Hsp90b1	2997	0.293	-0.0006	No
9	Ptpn11	3161	0.282	0.0052	No
10	Prkcb	3174	0.281	0.0175	No
11	Ralb	3442	0.266	0.0182	No
12	E2f1	3697	0.253	0.0189	No
13	Raf1	3796	0.248	0.0260	No
14	Map2k6	3910	0.243	0.0322	No
15	Rptor	4076	0.234	0.0358	No
16	Vav3	4444	0.220	0.0302	No
17	Itpr2	4466	0.219	0.0393	No
18	Rit1	4584	0.215	0.0441	No
19	Tsc2	4805	0.206	0.0441	No
20	Prkar2a	5029	0.197	0.0436	No
21	Smad2	5208	0.192	0.0447	No
22	Actr2	5234	0.191	0.0523	No
23	Camk4	5256	0.190	0.0601	No
24	Sla	5363	0.186	0.0640	No
25	Grk2	5484	0.181	0.0672	No
26	Mapkap1	5650	0.175	0.0681	No
27	Atf1	5704	0.173	0.0737	No
28	Map3k7	5812	0.169	0.0768	No
29	Cdk2	5897	0.165	0.0807	No
30	Mknk1	5925	0.164	0.0871	No
31	Gsk3b	6203	0.154	0.0823	No
32	Ngf	6246	0.152	0.0874	No
33	Pak4	6262	0.152	0.0937	No
34	Nod1	6678	0.138	0.0823	No
35	Grb2	6925	0.130	0.0777	No
36	Mapk9	7217	0.120	0.0708	No
37	Tbk1	7522	0.113	0.0630	No
38	Akt1	7706	0.107	0.0601	No
39	Pten	7747	0.106	0.0632	No
40	Ripk1	7897	0.101	0.0615	No
41	Mapk8	8556	0.082	0.0372	No
42	Mapk1	8667	0.078	0.0361	No
43	Actr3	8752	0.076	0.0360	No
44	Cab39	8952	0.069	0.0307	No
45	Irak4	9406	0.057	0.0140	No
46	Calr	9614	0.050	0.0074	No
47	Eif4e	9667	0.048	0.0074	No
48	Traf2	9973	0.039	-0.0038	No
49	Ube2d3	10228	0.031	-0.0132	No
50	Pdk1	10317	0.029	-0.0156	No
51	Tnfrsf1a	10540	0.022	-0.0241	No
52	Nck1	10551	0.021	-0.0235	No
53	Pin1	11065	0.007	-0.0450	No
54	Akt1s1	11148	0.005	-0.0483	No
55	Arpc3	11464	-0.001	-0.0616	No
56	Mknk2	11637	-0.006	-0.0686	No
57	Arf1	11743	-0.010	-0.0727	No
58	Ube2n	11842	-0.013	-0.0763	No
59	Ywhab	12056	-0.019	-0.0845	No
60	Ppp2r1b	12172	-0.022	-0.0883	No
61	Acaca	12289	-0.026	-0.0921	No
62	Rps6ka1	12597	-0.034	-0.1036	No
63	Rps6ka3	12670	-0.036	-0.1050	No
64	Cab39l	12677	-0.036	-0.1036	No
65	Stat2	13194	-0.052	-0.1232	No
66	Plcg1	13240	-0.054	-0.1227	No
67	Nfkbib	13981	-0.076	-0.1507	No
68	Arhgdia	15203	-0.117	-0.1973	No
69	Cxcr4	15827	-0.138	-0.2175	No
70	Prkag1	15880	-0.140	-0.2133	No
71	Prkaa2	17416	-0.194	-0.2698	Yes
72	Egfr	17585	-0.200	-0.2678	Yes
73	Slc2a1	17670	-0.204	-0.2621	Yes
74	Fgf22	17696	-0.206	-0.2538	Yes
75	Pik3r3	17770	-0.209	-0.2475	Yes
76	Rac1	17836	-0.211	-0.2406	Yes
77	Dusp3	17838	-0.211	-0.2311	Yes
78	Map2k3	18065	-0.221	-0.2307	Yes
79	Il4	18086	-0.223	-0.2214	Yes
80	Myd88	18129	-0.225	-0.2129	Yes
81	Sfn	19179	-0.270	-0.2453	Yes
82	Them4	19489	-0.283	-0.2455	Yes
83	Lck	20297	-0.324	-0.2651	Yes
84	Dapp1	20322	-0.325	-0.2514	Yes
85	Il2rg	20479	-0.334	-0.2428	Yes
86	Pitx2	20601	-0.341	-0.2325	Yes
87	Ap2m1	20685	-0.348	-0.2202	Yes
88	Cdkn1a	21058	-0.372	-0.2191	Yes
89	Cdk4	21293	-0.387	-0.2115	Yes
90	Pla2g12a	21399	-0.394	-0.1981	Yes
91	Pfn1	21716	-0.421	-0.1924	Yes
92	Cfl1	22057	-0.452	-0.1863	Yes
93	Ppp1ca	22151	-0.461	-0.1693	Yes
94	Csnk2b	22496	-0.499	-0.1613	Yes
95	Ecsit	22552	-0.506	-0.1406	Yes
96	Ddit3	22620	-0.517	-0.1200	Yes
97	Mapk10	22786	-0.547	-0.1022	Yes
98	Hras	22941	-0.571	-0.0828	Yes
99	Sqstm1	23020	-0.586	-0.0595	Yes
100	Gna14	23514	-0.818	-0.0432	Yes
101	Adcy2	23595	-1.054	0.0012	Yes