Details for gene set HALLMARK_P53

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group1_versus_Group3.GMP.mono_Pheno.cls #Group1_versus_Group3_repos
Phenotype	GMP.mono_Pheno.cls#Group1_versus_Group3_repos
Upregulated in class	2
GeneSet	HALLMARK_P53_PATHWAY
Enrichment Score (ES)	-0.28349227
Normalized Enrichment Score (NES)	-1.1819793
Nominal p-value	0.2457627
FDR q-value	0.5939728
FWER p-Value	0.91

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	H2ac25	75	0.847	0.0161	No
2	Ak1	176	0.734	0.0286	No
3	Fos	365	0.629	0.0349	No
4	Slc7a11	549	0.562	0.0399	No
5	Tob1	711	0.531	0.0451	No
6	Btg1	1119	0.457	0.0382	No
7	Jun	1354	0.424	0.0379	No
8	Trib3	1491	0.409	0.0414	No
9	Abcc5	1659	0.392	0.0432	No
10	Clca2	2202	0.352	0.0281	No
11	Sat1	2363	0.340	0.0290	No
12	Atf3	2446	0.331	0.0331	No
13	Plk2	2566	0.321	0.0353	No
14	Hdac3	2656	0.315	0.0387	No
15	Ephx1	2957	0.295	0.0326	No
16	Cdh13	2983	0.294	0.0383	No
17	Apaf1	3162	0.282	0.0371	No
18	Stom	3240	0.278	0.0401	No
19	Tgfa	3380	0.269	0.0404	No
20	Tchh	3385	0.269	0.0463	No
21	Aen	3642	0.255	0.0412	No
22	Trafd1	3798	0.248	0.0403	No
23	Fdxr	3953	0.240	0.0392	No
24	Dgka	3991	0.239	0.0431	No
25	Ddb2	4010	0.238	0.0477	No
26	Slc35d1	4028	0.237	0.0524	No
27	Polh	4030	0.237	0.0577	No
28	Sphk1	4118	0.232	0.0593	No
29	Osgin1	4247	0.229	0.0591	No
30	Blcap	4294	0.228	0.0623	No
31	F2r	4305	0.227	0.0671	No
32	Ccp110	4334	0.226	0.0710	No
33	Ldhb	4641	0.213	0.0628	No
34	App	4711	0.210	0.0646	No
35	Alox8	4732	0.209	0.0686	No
36	Baiap2	4773	0.207	0.0716	No
37	Foxo3	4799	0.207	0.0752	No
38	Hbegf	5076	0.195	0.0679	No
39	Btg2	5190	0.193	0.0675	No
40	Mdm2	5203	0.192	0.0713	No
41	Kif13b	5406	0.185	0.0669	No
42	Cdkn2aip	5635	0.175	0.0612	No
43	Slc3a2	5894	0.165	0.0540	No
44	Rab40c	6240	0.153	0.0427	No
45	Hspa4l	6382	0.148	0.0401	No
46	Elp1	6690	0.137	0.0301	No
47	Hmox1	6783	0.134	0.0293	No
48	Wwp1	6795	0.134	0.0318	No
49	Tsc22d1	7023	0.126	0.0250	No
50	Klf4	7133	0.123	0.0232	No
51	Sp1	7156	0.123	0.0250	No
52	Fbxw7	7221	0.120	0.0250	No
53	Csrnp2	7286	0.118	0.0250	No
54	Rb1	7708	0.107	0.0095	No
55	Hexim1	7787	0.105	0.0085	No
56	Cebpa	7858	0.103	0.0079	No
57	Cgrrf1	8581	0.081	-0.0211	No
58	Mapkapk3	8801	0.074	-0.0287	No
59	Slc19a2	8948	0.069	-0.0334	No
60	Ppp1r15a	9010	0.067	-0.0344	No
61	Ip6k2	9140	0.064	-0.0385	No
62	Vwa5a	9157	0.064	-0.0377	No
63	Traf4	9469	0.054	-0.0497	No
64	Irag2	9826	0.044	-0.0639	No
65	Nudt15	9910	0.041	-0.0665	No
66	Rnf19b	10128	0.034	-0.0750	No
67	Trp63	10231	0.031	-0.0786	No
68	Tax1bp3	10897	0.012	-0.1067	No
69	Cyfip2	10898	0.012	-0.1065	No
70	Sertad3	11183	0.004	-0.1185	No
71	Ercc5	11615	-0.006	-0.1368	No
72	Mknk2	11637	-0.006	-0.1375	No
73	Acvr1b	11885	-0.014	-0.1477	No
74	Dram1	11898	-0.014	-0.1479	No
75	Ralgds	12023	-0.018	-0.1528	No
76	Rad9a	12028	-0.018	-0.1526	No
77	Ccnk	12254	-0.025	-0.1616	No
78	Prkab1	12328	-0.026	-0.1641	No
79	Ninj1	12350	-0.027	-0.1644	No
80	S100a10	12425	-0.030	-0.1669	No
81	Ddit4	12460	-0.031	-0.1676	No
82	Rgs16	12492	-0.031	-0.1683	No
83	H1f2	12552	-0.033	-0.1700	No
84	Tnni1	12569	-0.033	-0.1699	No
85	Txnip	12765	-0.039	-0.1774	No
86	Mxd1	12833	-0.041	-0.1793	No
87	Eps8l2	12896	-0.043	-0.1810	No
88	Cd82	12943	-0.044	-0.1819	No
89	Rchy1	13032	-0.047	-0.1846	No
90	Rxra	13250	-0.054	-0.1927	No
91	Mxd4	13385	-0.059	-0.1970	No
92	Ei24	13445	-0.061	-0.1982	No
93	Rad51c	13824	-0.072	-0.2126	No
94	Fam162a	13988	-0.077	-0.2179	No
95	Rhbdf2	14088	-0.080	-0.2203	No
96	Dcxr	14153	-0.082	-0.2211	No
97	Sesn1	14295	-0.086	-0.2252	No
98	Tspyl2	14379	-0.089	-0.2267	No
99	Rap2b	14392	-0.089	-0.2251	No
100	Zfp365	14512	-0.094	-0.2281	No
101	Pidd1	14774	-0.102	-0.2369	No
102	Trp53	14982	-0.110	-0.2432	No
103	Perp	15022	-0.111	-0.2424	No
104	Abhd4	15071	-0.112	-0.2419	No
105	Rrad	15121	-0.114	-0.2414	No
106	Plxnb2	15173	-0.116	-0.2409	No
107	Coq8a	15232	-0.118	-0.2407	No
108	Zbtb16	15288	-0.120	-0.2403	No
109	Plk3	15291	-0.120	-0.2377	No
110	Pom121	15594	-0.130	-0.2476	No
111	Notch1	15690	-0.134	-0.2486	No
112	Ctsf	15888	-0.140	-0.2538	No
113	Socs1	15945	-0.143	-0.2529	No
114	Tcn2	16078	-0.148	-0.2552	No
115	Vdr	16124	-0.149	-0.2537	No
116	Tm7sf3	16164	-0.151	-0.2519	No
117	Pcna	16197	-0.152	-0.2498	No
118	Casp1	16308	-0.155	-0.2510	No
119	Ccng1	16418	-0.159	-0.2520	No
120	Nol8	16562	-0.164	-0.2543	No
121	Tap1	17013	-0.179	-0.2695	No
122	Xpc	17093	-0.181	-0.2687	No
123	Def6	17152	-0.184	-0.2670	No
124	Ptpre	17214	-0.186	-0.2654	No
125	St14	17300	-0.190	-0.2647	No
126	Sdc1	17575	-0.200	-0.2718	No
127	Ndrg1	17644	-0.203	-0.2701	No
128	Epha2	17649	-0.203	-0.2656	No
129	Cdk5r1	17729	-0.207	-0.2643	No
130	Pitpnc1	17837	-0.211	-0.2640	No
131	Irak1	17946	-0.215	-0.2637	No
132	Tgfb1	17962	-0.216	-0.2594	No
133	Cdkn2a	17995	-0.218	-0.2558	No
134	Wrap73	18075	-0.222	-0.2541	No
135	Zmat3	18727	-0.252	-0.2761	No
136	Retsat	18846	-0.255	-0.2754	No
137	Steap3	18998	-0.263	-0.2758	No
138	Sfn	19179	-0.270	-0.2773	Yes
139	Sec61a1	19273	-0.272	-0.2751	Yes
140	Iscu	19307	-0.274	-0.2702	Yes
141	Cd81	19417	-0.280	-0.2685	Yes
142	Ccnd3	19459	-0.281	-0.2638	Yes
143	Ccnd2	19722	-0.293	-0.2683	Yes
144	Ada	19870	-0.301	-0.2677	Yes
145	Tprkb	19895	-0.302	-0.2619	Yes
146	Abat	19926	-0.304	-0.2562	Yes
147	S100a4	19968	-0.306	-0.2510	Yes
148	Ppm1d	19975	-0.306	-0.2443	Yes
149	Rpl18	20094	-0.313	-0.2422	Yes
150	Fas	20183	-0.318	-0.2387	Yes
151	Pvt1	20199	-0.319	-0.2320	Yes
152	Fgf13	20288	-0.324	-0.2284	Yes
153	Ier5	20378	-0.328	-0.2247	Yes
154	Pdgfa	20379	-0.328	-0.2172	Yes
155	Ankra2	20486	-0.335	-0.2141	Yes
156	Dnttip2	20545	-0.338	-0.2089	Yes
157	Tnfsf9	20556	-0.339	-0.2016	Yes
158	Bax	20624	-0.342	-0.1967	Yes
159	Zfp36l1	20631	-0.343	-0.1891	Yes
160	Ptpn14	20634	-0.343	-0.1813	Yes
161	Klk8	20724	-0.350	-0.1772	Yes
162	Ctsd	20793	-0.354	-0.1720	Yes
163	Rps12	20802	-0.355	-0.1642	Yes
164	Ifi30	20900	-0.362	-0.1601	Yes
165	H2aj	20914	-0.363	-0.1524	Yes
166	Prmt2	20963	-0.365	-0.1461	Yes
167	Rps27l	21016	-0.368	-0.1399	Yes
168	Cdkn1a	21058	-0.372	-0.1332	Yes
169	Bak1	21146	-0.377	-0.1283	Yes
170	Pmm1	21454	-0.398	-0.1323	Yes
171	Jag2	21473	-0.399	-0.1240	Yes
172	Fuca1	21509	-0.402	-0.1163	Yes
173	Hint1	21579	-0.409	-0.1099	Yes
174	Triap1	21642	-0.414	-0.1031	Yes
175	Tpd52l1	21740	-0.424	-0.0976	Yes
176	Gadd45a	21810	-0.431	-0.0907	Yes
177	Nupr1	21848	-0.435	-0.0824	Yes
178	Rack1	21930	-0.442	-0.0758	Yes
179	Lif	22045	-0.451	-0.0703	Yes
180	Procr	22218	-0.467	-0.0670	Yes
181	Phlda3	22308	-0.477	-0.0600	Yes
182	Rrp8	22453	-0.492	-0.0549	Yes
183	Itgb4	22571	-0.509	-0.0482	Yes
184	Rpl36	22599	-0.515	-0.0377	Yes
185	Ddit3	22620	-0.517	-0.0267	Yes
186	Hras	22941	-0.571	-0.0273	Yes
187	Ier3	23057	-0.595	-0.0187	Yes
188	Vamp8	23104	-0.609	-0.0067	Yes
189	Gls2	23145	-0.622	0.0057	Yes
190	Gm2a	23210	-0.642	0.0177	Yes