Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group1_versus_Group2.GMP.mono_Pheno.cls #Group1_versus_Group2_repos
Phenotype	GMP.mono_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.30542767
Normalized Enrichment Score (NES)	-1.4232999
Nominal p-value	0.08118812
FDR q-value	0.12990054
FWER p-Value	0.5

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Itpr2	1400	0.477	-0.0373	No
2	Prkcb	2017	0.415	-0.0441	No
3	Adcy2	2062	0.412	-0.0267	No
4	Tiam1	2684	0.367	-0.0359	No
5	Map2k6	2730	0.364	-0.0208	No
6	Vav3	3957	0.286	-0.0596	No
7	Grk2	4049	0.280	-0.0504	No
8	Camk4	4077	0.279	-0.0385	No
9	Tsc2	4185	0.272	-0.0304	No
10	Ngf	4245	0.269	-0.0203	No
11	Sla	4717	0.246	-0.0289	No
12	Rptor	4954	0.234	-0.0280	No
13	Mapk8	5458	0.213	-0.0394	No
14	Mknk1	5504	0.211	-0.0315	No
15	Dapp1	5549	0.209	-0.0236	No
16	Fgf22	5565	0.208	-0.0145	No
17	Plcb1	5940	0.195	-0.0214	No
18	E2f1	6107	0.189	-0.0196	No
19	Pak4	6376	0.178	-0.0227	No
20	Cdk2	6864	0.160	-0.0359	No
21	Slc2a1	7113	0.151	-0.0394	No
22	Prkaa2	7569	0.136	-0.0523	No
23	Tbk1	7688	0.133	-0.0512	No
24	Them4	7833	0.127	-0.0513	No
25	Pikfyve	8161	0.115	-0.0599	No
26	Ppp2r1b	8288	0.111	-0.0600	No
27	Akt1s1	8297	0.111	-0.0552	No
28	Tnfrsf1a	8513	0.104	-0.0595	No
29	Map3k7	8516	0.104	-0.0548	No
30	Mapk9	8603	0.101	-0.0537	No
31	Pin1	8772	0.096	-0.0564	No
32	Raf1	9109	0.085	-0.0667	No
33	Il4	9412	0.075	-0.0760	No
34	Ptpn11	9862	0.062	-0.0922	No
35	Irak4	10819	0.032	-0.1314	No
36	Grb2	10982	0.026	-0.1370	No
37	Rps6ka1	11040	0.024	-0.1383	No
38	Ripk1	11953	-0.002	-0.1770	No
39	Actr3	12069	-0.006	-0.1816	No
40	Pten	12075	-0.006	-0.1815	No
41	Cab39l	12151	-0.009	-0.1843	No
42	Mapkap1	12165	-0.009	-0.1844	No
43	Mapk1	12389	-0.016	-0.1931	No
44	Nfkbib	12824	-0.029	-0.2102	No
45	Nod1	12868	-0.031	-0.2106	No
46	Mknk2	13081	-0.038	-0.2179	No
47	Sfn	13177	-0.041	-0.2200	No
48	Smad2	13282	-0.044	-0.2224	No
49	Gsk3b	13395	-0.047	-0.2249	No
50	Cdk1	13724	-0.058	-0.2361	No
51	Stat2	14056	-0.068	-0.2470	No
52	Eif4e	14190	-0.072	-0.2493	No
53	Atf1	14242	-0.073	-0.2481	No
54	Nck1	14248	-0.074	-0.2448	No
55	Cdkn1b	14800	-0.091	-0.2640	No
56	Traf2	14945	-0.095	-0.2657	No
57	Ube2d3	15840	-0.125	-0.2979	No
58	Prkag1	16019	-0.131	-0.2993	Yes
59	Pik3r3	16061	-0.133	-0.2948	Yes
60	Ube2n	16152	-0.136	-0.2923	Yes
61	Plcg1	16212	-0.138	-0.2884	Yes
62	Ywhab	16444	-0.146	-0.2914	Yes
63	Pdk1	16534	-0.149	-0.2882	Yes
64	Ddit3	16616	-0.152	-0.2846	Yes
65	Dusp3	16848	-0.160	-0.2869	Yes
66	Ecsit	16850	-0.160	-0.2794	Yes
67	Prkar2a	17207	-0.173	-0.2865	Yes
68	Cab39	17212	-0.174	-0.2786	Yes
69	Ralb	17331	-0.178	-0.2752	Yes
70	Cxcr4	17449	-0.184	-0.2717	Yes
71	Egfr	17528	-0.186	-0.2663	Yes
72	Rps6ka3	17544	-0.187	-0.2582	Yes
73	Cltc	17715	-0.193	-0.2564	Yes
74	Actr2	17977	-0.203	-0.2580	Yes
75	Rit1	18104	-0.208	-0.2537	Yes
76	Acaca	18384	-0.219	-0.2553	Yes
77	Arhgdia	18891	-0.240	-0.2656	Yes
78	Gna14	18913	-0.241	-0.2553	Yes
79	Trib3	19037	-0.247	-0.2490	Yes
80	Sqstm1	19101	-0.249	-0.2400	Yes
81	Pfn1	19324	-0.260	-0.2373	Yes
82	Arpc3	20052	-0.297	-0.2544	Yes
83	Pitx2	20136	-0.302	-0.2438	Yes
84	Csnk2b	20825	-0.340	-0.2571	Yes
85	Pla2g12a	20986	-0.351	-0.2476	Yes
86	Cdk4	21212	-0.366	-0.2401	Yes
87	Arf1	21221	-0.366	-0.2233	Yes
88	Rac1	21223	-0.366	-0.2063	Yes
89	Mapk10	21246	-0.368	-0.1900	Yes
90	Cdkn1a	21542	-0.388	-0.1845	Yes
91	Map2k3	21784	-0.407	-0.1757	Yes
92	Ap2m1	22180	-0.443	-0.1718	Yes
93	Calr	22302	-0.457	-0.1556	Yes
94	Hras	22522	-0.485	-0.1422	Yes
95	Hsp90b1	22529	-0.486	-0.1198	Yes
96	Akt1	22654	-0.502	-0.1017	Yes
97	Cfl1	22735	-0.515	-0.0810	Yes
98	Lck	22799	-0.524	-0.0592	Yes
99	Ppp1ca	23017	-0.562	-0.0423	Yes
100	Il2rg	23317	-0.653	-0.0245	Yes
101	Myd88	23534	-0.803	0.0038	Yes