| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group2.GMP.mono_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.5825464 |
| Normalized Enrichment Score (NES) | -1.8695251 |
| Nominal p-value | 0.013752456 |
| FDR q-value | 0.05164757 |
| FWER p-Value | 0.027 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Btg2 | 3333 | 0.325 | -0.1363 | No |
| 2 | Igfbp5 | 3795 | 0.295 | -0.1506 | No |
| 3 | Sla | 4717 | 0.246 | -0.1854 | No |
| 4 | Gbe1 | 4895 | 0.237 | -0.1886 | No |
| 5 | Slc37a4 | 5415 | 0.214 | -0.2068 | No |
| 6 | Dapp1 | 5549 | 0.209 | -0.2087 | No |
| 7 | Tm7sf2 | 5595 | 0.206 | -0.2068 | No |
| 8 | Lta4h | 5742 | 0.203 | -0.2093 | No |
| 9 | Pgm1 | 5999 | 0.193 | -0.2167 | No |
| 10 | Slc2a1 | 7113 | 0.151 | -0.2615 | No |
| 11 | Cth | 7267 | 0.146 | -0.2653 | No |
| 12 | Fdxr | 7379 | 0.143 | -0.2674 | No |
| 13 | Idh1 | 7384 | 0.143 | -0.2650 | No |
| 14 | Ak4 | 7397 | 0.142 | -0.2629 | No |
| 15 | Tbk1 | 7688 | 0.133 | -0.2729 | No |
| 16 | Nfyc | 7850 | 0.126 | -0.2774 | No |
| 17 | Dhfr | 7991 | 0.121 | -0.2812 | No |
| 18 | Polr3g | 8246 | 0.112 | -0.2900 | No |
| 19 | Add3 | 9640 | 0.068 | -0.3481 | No |
| 20 | Mthfd2l | 9648 | 0.068 | -0.3472 | No |
| 21 | Egln3 | 10137 | 0.053 | -0.3671 | No |
| 22 | Me1 | 10348 | 0.047 | -0.3752 | No |
| 23 | G6pdx | 10555 | 0.039 | -0.3832 | No |
| 24 | Ccnf | 11340 | 0.014 | -0.4164 | No |
| 25 | Adipor2 | 11465 | 0.010 | -0.4215 | No |
| 26 | Itgb2 | 11540 | 0.008 | -0.4245 | No |
| 27 | Actr3 | 12069 | -0.006 | -0.4470 | No |
| 28 | Cfp | 12192 | -0.010 | -0.4520 | No |
| 29 | Sytl2 | 12311 | -0.014 | -0.4568 | No |
| 30 | Psph | 12776 | -0.028 | -0.4761 | No |
| 31 | Nfkbib | 12824 | -0.029 | -0.4775 | No |
| 32 | Gsr | 13035 | -0.036 | -0.4858 | No |
| 33 | Nufip1 | 13092 | -0.038 | -0.4875 | No |
| 34 | Slc1a5 | 13191 | -0.041 | -0.4909 | No |
| 35 | Hk2 | 13292 | -0.044 | -0.4944 | No |
| 36 | Niban1 | 13374 | -0.047 | -0.4970 | No |
| 37 | Gsk3b | 13395 | -0.047 | -0.4970 | No |
| 38 | Elovl5 | 13476 | -0.050 | -0.4995 | No |
| 39 | Ppp1r15a | 13524 | -0.052 | -0.5005 | No |
| 40 | Rpa1 | 13530 | -0.052 | -0.4998 | No |
| 41 | Slc2a3 | 13578 | -0.053 | -0.5008 | No |
| 42 | Bub1 | 13711 | -0.058 | -0.5054 | No |
| 43 | Phgdh | 13747 | -0.059 | -0.5058 | No |
| 44 | Tuba4a | 14049 | -0.068 | -0.5174 | No |
| 45 | Nup205 | 14204 | -0.072 | -0.5227 | No |
| 46 | Atp6v1d | 14270 | -0.074 | -0.5241 | No |
| 47 | Elovl6 | 14473 | -0.080 | -0.5312 | No |
| 48 | Serp1 | 14719 | -0.088 | -0.5401 | No |
| 49 | Mllt11 | 14749 | -0.089 | -0.5397 | No |
| 50 | Gga2 | 14775 | -0.090 | -0.5391 | No |
| 51 | Gtf2h1 | 14979 | -0.097 | -0.5460 | No |
| 52 | Gpi1 | 15009 | -0.098 | -0.5454 | No |
| 53 | Wars1 | 15449 | -0.113 | -0.5621 | No |
| 54 | Edem1 | 15538 | -0.117 | -0.5637 | No |
| 55 | P4ha1 | 15587 | -0.118 | -0.5636 | No |
| 56 | Xbp1 | 15665 | -0.121 | -0.5647 | No |
| 57 | Srd5a1 | 15754 | -0.124 | -0.5662 | No |
| 58 | Ube2d3 | 15840 | -0.125 | -0.5675 | No |
| 59 | Skap2 | 15853 | -0.126 | -0.5657 | No |
| 60 | Cdc25a | 16059 | -0.133 | -0.5720 | No |
| 61 | Pik3r3 | 16061 | -0.133 | -0.5697 | No |
| 62 | Sec11a | 16073 | -0.133 | -0.5677 | No |
| 63 | Eef1e1 | 16121 | -0.134 | -0.5672 | No |
| 64 | Pnp | 16197 | -0.137 | -0.5679 | No |
| 65 | Psme3 | 16286 | -0.141 | -0.5691 | No |
| 66 | Ddit4 | 16463 | -0.146 | -0.5739 | No |
| 67 | Sc5d | 16525 | -0.148 | -0.5738 | No |
| 68 | Pdk1 | 16534 | -0.149 | -0.5714 | No |
| 69 | Gmps | 16542 | -0.149 | -0.5690 | No |
| 70 | Ddit3 | 16616 | -0.152 | -0.5693 | No |
| 71 | Fgl2 | 16643 | -0.153 | -0.5677 | No |
| 72 | Pgk1 | 16726 | -0.156 | -0.5683 | No |
| 73 | Glrx | 16805 | -0.159 | -0.5687 | No |
| 74 | Psmc6 | 16883 | -0.162 | -0.5690 | No |
| 75 | Tcea1 | 16935 | -0.164 | -0.5682 | No |
| 76 | Acly | 17135 | -0.171 | -0.5736 | No |
| 77 | Immt | 17346 | -0.179 | -0.5793 | Yes |
| 78 | Nmt1 | 17353 | -0.179 | -0.5762 | Yes |
| 79 | Ung | 17356 | -0.179 | -0.5731 | Yes |
| 80 | Insig1 | 17425 | -0.182 | -0.5726 | Yes |
| 81 | Nfil3 | 17430 | -0.183 | -0.5694 | Yes |
| 82 | Cxcr4 | 17449 | -0.184 | -0.5669 | Yes |
| 83 | Qdpr | 17505 | -0.186 | -0.5658 | Yes |
| 84 | Gclc | 17691 | -0.192 | -0.5702 | Yes |
| 85 | Psmd14 | 17763 | -0.195 | -0.5697 | Yes |
| 86 | Slc6a6 | 17791 | -0.197 | -0.5672 | Yes |
| 87 | Tomm40 | 17841 | -0.198 | -0.5657 | Yes |
| 88 | Atp2a2 | 17845 | -0.198 | -0.5622 | Yes |
| 89 | Arpc5l | 17879 | -0.199 | -0.5599 | Yes |
| 90 | Actr2 | 17977 | -0.203 | -0.5604 | Yes |
| 91 | Rab1a | 17992 | -0.203 | -0.5572 | Yes |
| 92 | Stard4 | 18062 | -0.206 | -0.5564 | Yes |
| 93 | Rit1 | 18104 | -0.208 | -0.5544 | Yes |
| 94 | Acaca | 18384 | -0.219 | -0.5623 | Yes |
| 95 | Uchl5 | 18403 | -0.220 | -0.5590 | Yes |
| 96 | Ifrd1 | 18596 | -0.229 | -0.5630 | Yes |
| 97 | Ykt6 | 18686 | -0.231 | -0.5626 | Yes |
| 98 | Lgmn | 18702 | -0.231 | -0.5590 | Yes |
| 99 | Plod2 | 18801 | -0.236 | -0.5589 | Yes |
| 100 | Pitpnb | 18807 | -0.236 | -0.5547 | Yes |
| 101 | Ero1a | 18831 | -0.237 | -0.5514 | Yes |
| 102 | Bhlhe40 | 18940 | -0.242 | -0.5516 | Yes |
| 103 | Dhcr24 | 18983 | -0.244 | -0.5489 | Yes |
| 104 | Trib3 | 19037 | -0.247 | -0.5467 | Yes |
| 105 | Sqstm1 | 19101 | -0.249 | -0.5448 | Yes |
| 106 | Dhcr7 | 19114 | -0.250 | -0.5407 | Yes |
| 107 | Idi1 | 19143 | -0.252 | -0.5373 | Yes |
| 108 | Rrp9 | 19203 | -0.255 | -0.5352 | Yes |
| 109 | Sord | 19263 | -0.258 | -0.5330 | Yes |
| 110 | Mcm2 | 19282 | -0.258 | -0.5290 | Yes |
| 111 | Psma3 | 19447 | -0.268 | -0.5311 | Yes |
| 112 | Nampt | 19568 | -0.274 | -0.5312 | Yes |
| 113 | Coro1a | 19654 | -0.278 | -0.5298 | Yes |
| 114 | Uso1 | 19698 | -0.280 | -0.5265 | Yes |
| 115 | Mcm4 | 19709 | -0.281 | -0.5218 | Yes |
| 116 | Psmg1 | 19854 | -0.287 | -0.5227 | Yes |
| 117 | Tubg1 | 19855 | -0.287 | -0.5174 | Yes |
| 118 | Ufm1 | 19866 | -0.288 | -0.5126 | Yes |
| 119 | Hmgcr | 19970 | -0.292 | -0.5116 | Yes |
| 120 | Psmb5 | 20163 | -0.303 | -0.5143 | Yes |
| 121 | Rdh11 | 20304 | -0.309 | -0.5146 | Yes |
| 122 | Ppa1 | 20410 | -0.315 | -0.5133 | Yes |
| 123 | Ddx39a | 20545 | -0.323 | -0.5131 | Yes |
| 124 | Txnrd1 | 20550 | -0.324 | -0.5073 | Yes |
| 125 | Plk1 | 20579 | -0.325 | -0.5026 | Yes |
| 126 | Cd9 | 20616 | -0.328 | -0.4981 | Yes |
| 127 | Abcf2 | 20679 | -0.332 | -0.4947 | Yes |
| 128 | Sqle | 20685 | -0.332 | -0.4888 | Yes |
| 129 | Psma4 | 20695 | -0.333 | -0.4831 | Yes |
| 130 | M6pr | 20794 | -0.338 | -0.4811 | Yes |
| 131 | Cops5 | 20812 | -0.339 | -0.4756 | Yes |
| 132 | Tpi1 | 20926 | -0.347 | -0.4741 | Yes |
| 133 | Gla | 20934 | -0.348 | -0.4680 | Yes |
| 134 | Slc7a5 | 21122 | -0.359 | -0.4694 | Yes |
| 135 | Aldoa | 21160 | -0.362 | -0.4644 | Yes |
| 136 | Tes | 21179 | -0.363 | -0.4585 | Yes |
| 137 | Ccng1 | 21185 | -0.363 | -0.4521 | Yes |
| 138 | Hspa4 | 21338 | -0.375 | -0.4517 | Yes |
| 139 | Ppia | 21404 | -0.380 | -0.4475 | Yes |
| 140 | Pno1 | 21411 | -0.381 | -0.4408 | Yes |
| 141 | Cdkn1a | 21542 | -0.388 | -0.4392 | Yes |
| 142 | Cyb5b | 21589 | -0.392 | -0.4340 | Yes |
| 143 | Eno1b | 21647 | -0.395 | -0.4292 | Yes |
| 144 | Etf1 | 21653 | -0.396 | -0.4222 | Yes |
| 145 | Map2k3 | 21784 | -0.407 | -0.4203 | Yes |
| 146 | Psmd13 | 21814 | -0.409 | -0.4140 | Yes |
| 147 | Aurka | 21847 | -0.412 | -0.4078 | Yes |
| 148 | Psmc2 | 21873 | -0.414 | -0.4013 | Yes |
| 149 | Hmbs | 21905 | -0.417 | -0.3950 | Yes |
| 150 | Ssr1 | 22007 | -0.426 | -0.3915 | Yes |
| 151 | Fads2 | 22008 | -0.427 | -0.3837 | Yes |
| 152 | Canx | 22053 | -0.430 | -0.3777 | Yes |
| 153 | Hmgcs1 | 22086 | -0.434 | -0.3712 | Yes |
| 154 | Ldlr | 22112 | -0.436 | -0.3642 | Yes |
| 155 | Cyp51 | 22122 | -0.437 | -0.3566 | Yes |
| 156 | Fkbp2 | 22175 | -0.443 | -0.3507 | Yes |
| 157 | Eif2s2 | 22178 | -0.443 | -0.3427 | Yes |
| 158 | Ebp | 22220 | -0.447 | -0.3363 | Yes |
| 159 | Pdap1 | 22247 | -0.451 | -0.3291 | Yes |
| 160 | Calr | 22302 | -0.457 | -0.3231 | Yes |
| 161 | Mthfd2 | 22332 | -0.461 | -0.3159 | Yes |
| 162 | Stip1 | 22391 | -0.466 | -0.3098 | Yes |
| 163 | Psmc4 | 22400 | -0.467 | -0.3016 | Yes |
| 164 | Bcat1 | 22405 | -0.468 | -0.2932 | Yes |
| 165 | Hsp90b1 | 22529 | -0.486 | -0.2895 | Yes |
| 166 | Tmem97 | 22722 | -0.512 | -0.2884 | Yes |
| 167 | Psmd12 | 22757 | -0.518 | -0.2803 | Yes |
| 168 | Slc1a4 | 22764 | -0.519 | -0.2711 | Yes |
| 169 | Sdf2l1 | 22826 | -0.528 | -0.2640 | Yes |
| 170 | Cct6a | 22848 | -0.530 | -0.2552 | Yes |
| 171 | Prdx1 | 22911 | -0.542 | -0.2480 | Yes |
| 172 | Got1 | 23011 | -0.560 | -0.2419 | Yes |
| 173 | Ldha | 23045 | -0.569 | -0.2329 | Yes |
| 174 | Psat1 | 23051 | -0.570 | -0.2227 | Yes |
| 175 | Hspe1 | 23056 | -0.571 | -0.2124 | Yes |
| 176 | Pfkl | 23068 | -0.574 | -0.2024 | Yes |
| 177 | Slc7a11 | 23182 | -0.599 | -0.1963 | Yes |
| 178 | Hspa5 | 23275 | -0.632 | -0.1886 | Yes |
| 179 | Rpn1 | 23285 | -0.638 | -0.1773 | Yes |
| 180 | Ifi30 | 23292 | -0.642 | -0.1658 | Yes |
| 181 | Hspa9 | 23297 | -0.644 | -0.1542 | Yes |
| 182 | Serpinh1 | 23328 | -0.655 | -0.1435 | Yes |
| 183 | Rrm2 | 23350 | -0.663 | -0.1322 | Yes |
| 184 | Tfrc | 23400 | -0.689 | -0.1217 | Yes |
| 185 | Hspd1 | 23427 | -0.703 | -0.1100 | Yes |
| 186 | Ctsc | 23435 | -0.707 | -0.0973 | Yes |
| 187 | Fads1 | 23455 | -0.718 | -0.0850 | Yes |
| 188 | Acsl3 | 23471 | -0.730 | -0.0723 | Yes |
| 189 | Shmt2 | 23484 | -0.750 | -0.0591 | Yes |
| 190 | Cacybp | 23495 | -0.758 | -0.0456 | Yes |
| 191 | Vldlr | 23578 | -0.882 | -0.0330 | Yes |
| 192 | Nupr1 | 23589 | -0.907 | -0.0168 | Yes |
| 193 | Asns | 23612 | -0.998 | 0.0005 | Yes |

