Details for gene set HALLMARK_E2F

Table: GSEA Results Summary

Dataset	GMP.GMP.mono_Pheno.cls #Group1_versus_Group2.GMP.mono_Pheno.cls #Group1_versus_Group2_repos
Phenotype	GMP.mono_Pheno.cls#Group1_versus_Group2_repos
Upregulated in class	1
GeneSet	HALLMARK_E2F_TARGETS
Enrichment Score (ES)	-0.42688888
Normalized Enrichment Score (NES)	-1.5799428
Nominal p-value	0.10887097
FDR q-value	0.06806146
FWER p-Value	0.274

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Wdr90	1253	0.497	-0.0399	No
2	Dscc1	2328	0.392	-0.0750	No
3	Brms1l	3356	0.323	-0.1100	No
4	Cdkn3	3364	0.322	-0.1014	No
5	Brca2	3667	0.302	-0.1061	No
6	Ube2s	4653	0.248	-0.1413	No
7	Depdc1a	4924	0.235	-0.1464	No
8	Ube2t	6239	0.183	-0.1974	No
9	Nudt21	6392	0.178	-0.1991	No
10	Rfc2	6679	0.166	-0.2067	No
11	Prim2	6785	0.162	-0.2068	No
12	Wee1	7241	0.147	-0.2222	No
13	Cdca3	7351	0.143	-0.2229	No
14	Cdc25b	7410	0.142	-0.2215	No
15	Diaph3	7471	0.140	-0.2202	No
16	Melk	7634	0.134	-0.2235	No
17	Kif18b	7942	0.123	-0.2332	No
18	Pold1	8008	0.121	-0.2327	No
19	Stag1	8094	0.118	-0.2331	No
20	Prkdc	8111	0.117	-0.2305	No
21	Mms22l	8192	0.114	-0.2308	No
22	Pole	8261	0.112	-0.2306	No
23	Mlh1	8423	0.107	-0.2346	No
24	Cenpm	8633	0.100	-0.2408	No
25	Timeless	8720	0.097	-0.2418	No
26	Exosc8	8904	0.092	-0.2471	No
27	Cit	8915	0.092	-0.2450	No
28	Hmga1b	9085	0.086	-0.2499	No
29	Luc7l3	9398	0.076	-0.2611	No
30	Rad21	9441	0.074	-0.2609	No
31	Espl1	9467	0.074	-0.2599	No
32	Ccnb2	9504	0.073	-0.2595	No
33	Bard1	9650	0.068	-0.2638	No
34	Atad2	9880	0.061	-0.2719	No
35	Zw10	9881	0.061	-0.2702	No
36	Pds5b	10093	0.054	-0.2777	No
37	Pttg1	10098	0.054	-0.2764	No
38	Srsf2	10680	0.036	-0.3003	No
39	Mre11a	10822	0.032	-0.3054	No
40	Chek2	10887	0.030	-0.3073	No
41	Pola2	10978	0.027	-0.3105	No
42	Rfc1	11222	0.019	-0.3203	No
43	Pms2	11246	0.018	-0.3208	No
44	Smc6	11324	0.015	-0.3237	No
45	Pold3	11351	0.014	-0.3244	No
46	Donson	11688	0.005	-0.3386	No
47	Ezh2	11716	0.004	-0.3397	No
48	Tra2b	11736	0.004	-0.3404	No
49	Dclre1b	11832	0.001	-0.3444	No
50	Nup107	11931	-0.002	-0.3486	No
51	Kif2c	11980	-0.003	-0.3505	No
52	Spag5	11994	-0.004	-0.3510	No
53	Hmgb3	12013	-0.004	-0.3516	No
54	Brca1	12047	-0.006	-0.3529	No
55	Cdkn2c	12093	-0.007	-0.3546	No
56	Eed	12138	-0.008	-0.3563	No
57	Tk1	12198	-0.010	-0.3585	No
58	Ing3	12241	-0.012	-0.3600	No
59	Dlgap5	12462	-0.019	-0.3689	No
60	Hus1	12522	-0.020	-0.3708	No
61	H2ax	12568	-0.021	-0.3722	No
62	Kif22	12788	-0.028	-0.3807	No
63	Hnrnpd	12880	-0.031	-0.3838	No
64	Xpo1	12944	-0.033	-0.3856	No
65	Mcm5	13148	-0.040	-0.3931	No
66	Racgap1	13182	-0.041	-0.3934	No
67	Smc4	13188	-0.041	-0.3925	No
68	Pan2	13219	-0.042	-0.3926	No
69	Trp53	13306	-0.045	-0.3951	No
70	Ilf3	13330	-0.046	-0.3948	No
71	Tmpo	13382	-0.047	-0.3957	No
72	E2f8	13510	-0.051	-0.3997	No
73	Rpa1	13530	-0.052	-0.3991	No
74	Cdk1	13724	-0.058	-0.4058	No
75	Mxd3	13726	-0.058	-0.4042	No
76	Cse1l	13772	-0.060	-0.4045	No
77	Mcm6	13780	-0.060	-0.4032	No
78	Rpa2	13801	-0.061	-0.4023	No
79	Cdkn2a	13886	-0.064	-0.4042	No
80	Chek1	14061	-0.068	-0.4098	No
81	Rad50	14076	-0.069	-0.4085	No
82	Syncrip	14079	-0.069	-0.4067	No
83	Mki67	14183	-0.072	-0.4091	No
84	Nup205	14204	-0.072	-0.4080	No
85	Top2a	14220	-0.073	-0.4066	No
86	Rnaseh2a	14324	-0.076	-0.4089	No
87	Msh2	14418	-0.079	-0.4108	No
88	Asf1b	14447	-0.080	-0.4098	No
89	Dek	14532	-0.082	-0.4111	No
90	Mybl2	14582	-0.084	-0.4109	No
91	Ctcf	14660	-0.086	-0.4118	No
92	Cenpe	14669	-0.087	-0.4098	No
93	Cks2	14680	-0.087	-0.4078	No
94	Psmc3ip	14726	-0.089	-0.4073	No
95	Cdkn1b	14800	-0.091	-0.4080	No
96	Cnot9	14926	-0.095	-0.4107	No
97	Prdx4	15110	-0.102	-0.4157	No
98	Smc3	15144	-0.103	-0.4143	No
99	Pnn	15272	-0.107	-0.4168	No
100	Ncapd2	15273	-0.107	-0.4139	No
101	Xrcc6	15365	-0.110	-0.4147	No
102	Spc25	15419	-0.112	-0.4139	No
103	Kif4	15473	-0.114	-0.4131	No
104	Rad51ap1	15680	-0.122	-0.4185	No
105	Plk4	15877	-0.127	-0.4234	Yes
106	Aurkb	15907	-0.128	-0.4212	Yes
107	Bub1b	15929	-0.128	-0.4186	Yes
108	Hells	15989	-0.130	-0.4175	Yes
109	Cdc25a	16059	-0.133	-0.4168	Yes
110	Suv39h1	16107	-0.134	-0.4152	Yes
111	Tbrg4	16119	-0.134	-0.4119	Yes
112	Trip13	16125	-0.135	-0.4085	Yes
113	Tacc3	16147	-0.136	-0.4056	Yes
114	Orc6	16196	-0.137	-0.4039	Yes
115	Nbn	16465	-0.146	-0.4114	Yes
116	Gins3	16665	-0.153	-0.4157	Yes
117	Pole4	16702	-0.155	-0.4130	Yes
118	Gins1	16731	-0.156	-0.4099	Yes
119	Mad2l1	16734	-0.156	-0.4057	Yes
120	Tipin	16792	-0.158	-0.4038	Yes
121	Rad1	16804	-0.159	-0.3999	Yes
122	Nup153	16831	-0.160	-0.3966	Yes
123	Smc1a	16844	-0.160	-0.3927	Yes
124	Gspt1	16870	-0.161	-0.3894	Yes
125	Spc24	16931	-0.164	-0.3875	Yes
126	Usp1	16961	-0.165	-0.3842	Yes
127	Cdca8	17024	-0.167	-0.3823	Yes
128	Asf1a	17127	-0.171	-0.3820	Yes
129	Cbx5	17148	-0.171	-0.3781	Yes
130	Orc2	17159	-0.172	-0.3738	Yes
131	Ccp110	17224	-0.174	-0.3718	Yes
132	Lig1	17278	-0.176	-0.3692	Yes
133	Gins4	17352	-0.179	-0.3675	Yes
134	Ung	17356	-0.179	-0.3627	Yes
135	Nop56	17380	-0.180	-0.3587	Yes
136	Ppm1d	17417	-0.182	-0.3553	Yes
137	Ubr7	17704	-0.192	-0.3622	Yes
138	Lsm8	17709	-0.192	-0.3571	Yes
139	Mcm7	17889	-0.200	-0.3593	Yes
140	Ipo7	17916	-0.201	-0.3549	Yes
141	Tcf19	17968	-0.202	-0.3515	Yes
142	Tubb5	18137	-0.209	-0.3530	Yes
143	Dnmt1	18151	-0.209	-0.3478	Yes
144	Lmnb1	18407	-0.220	-0.3526	Yes
145	Rfc3	18411	-0.221	-0.3467	Yes
146	Anp32e	18494	-0.225	-0.3441	Yes
147	Mcm3	18675	-0.231	-0.3454	Yes
148	Hmmr	18786	-0.235	-0.3437	Yes
149	Myc	18834	-0.237	-0.3392	Yes
150	Nasp	18893	-0.240	-0.3351	Yes
151	H2az1	19072	-0.248	-0.3359	Yes
152	Eif2s1	19178	-0.253	-0.3334	Yes
153	Mcm2	19282	-0.258	-0.3308	Yes
154	Jpt1	19444	-0.268	-0.3303	Yes
155	Stmn1	19466	-0.269	-0.3238	Yes
156	Cdc20	19514	-0.271	-0.3184	Yes
157	Slbp	19646	-0.277	-0.3164	Yes
158	Cks1b	19689	-0.279	-0.3105	Yes
159	Mcm4	19709	-0.281	-0.3037	Yes
160	Ak2	19834	-0.286	-0.3011	Yes
161	Tubg1	19855	-0.287	-0.2941	Yes
162	Psip1	19876	-0.288	-0.2871	Yes
163	Rpa3	19946	-0.291	-0.2820	Yes
164	Lbr	19982	-0.293	-0.2755	Yes
165	Pold2	20011	-0.294	-0.2686	Yes
166	Dut	20056	-0.297	-0.2624	Yes
167	Shmt1	20225	-0.307	-0.2612	Yes
168	Pop7	20535	-0.323	-0.2655	Yes
169	Ddx39a	20545	-0.323	-0.2570	Yes
170	Plk1	20579	-0.325	-0.2495	Yes
171	Paics	20596	-0.327	-0.2413	Yes
172	Nap1l1	20650	-0.330	-0.2345	Yes
173	Rbbp7	20722	-0.334	-0.2284	Yes
174	Hmgb2	20847	-0.342	-0.2243	Yes
175	Rad51c	20987	-0.351	-0.2206	Yes
176	Cdk4	21212	-0.366	-0.2202	Yes
177	Ppp1r8	21456	-0.384	-0.2200	Yes
178	Cdkn1a	21542	-0.388	-0.2130	Yes
179	Phf5a	21563	-0.390	-0.2032	Yes
180	Nolc1	21728	-0.402	-0.1992	Yes
181	Pcna	21750	-0.404	-0.1890	Yes
182	Aurka	21847	-0.412	-0.1818	Yes
183	Dctpp1	21915	-0.418	-0.1732	Yes
184	Prps1	22023	-0.428	-0.1661	Yes
185	Ssrp1	22219	-0.447	-0.1622	Yes
186	Snrpb	22325	-0.460	-0.1540	Yes
187	Mthfd2	22332	-0.461	-0.1417	Yes
188	Pa2g4	22710	-0.510	-0.1438	Yes
189	Srsf1	22784	-0.522	-0.1326	Yes
190	Lyar	22904	-0.541	-0.1229	Yes
191	Birc5	23200	-0.605	-0.1189	Yes
192	Dck	23261	-0.628	-0.1043	Yes
193	Ranbp1	23290	-0.642	-0.0879	Yes
194	Rrm2	23350	-0.663	-0.0722	Yes
195	Tfrc	23400	-0.689	-0.0554	Yes
196	Nme1	23458	-0.720	-0.0381	Yes
197	Ran	23535	-0.805	-0.0193	Yes
198	Ccne1	23563	-0.843	0.0026	Yes