| Dataset | GMP.GMP.mono_Pheno.cls #Group1_versus_Group2.GMP.mono_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | GMP.mono_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_COMPLEMENT |
| Enrichment Score (ES) | -0.3495062 |
| Normalized Enrichment Score (NES) | -1.4171966 |
| Nominal p-value | 0.010162601 |
| FDR q-value | 0.12891401 |
| FWER p-Value | 0.518 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | F8 | 8 | 1.263 | 0.0287 | No |
| 2 | Kcnip3 | 165 | 0.798 | 0.0404 | No |
| 3 | Pdgfb | 748 | 0.580 | 0.0289 | No |
| 4 | Serpinb2 | 1045 | 0.529 | 0.0284 | No |
| 5 | Gzmb | 1109 | 0.518 | 0.0376 | No |
| 6 | L3mbtl4 | 1322 | 0.485 | 0.0397 | No |
| 7 | Ehd1 | 1406 | 0.476 | 0.0471 | No |
| 8 | Cpq | 1795 | 0.432 | 0.0405 | No |
| 9 | Gp1ba | 1875 | 0.426 | 0.0469 | No |
| 10 | Cda | 1890 | 0.425 | 0.0561 | No |
| 11 | F2 | 2309 | 0.393 | 0.0473 | No |
| 12 | Lcp2 | 2395 | 0.388 | 0.0526 | No |
| 13 | Ctso | 2723 | 0.365 | 0.0471 | No |
| 14 | Brpf3 | 2795 | 0.359 | 0.0523 | No |
| 15 | Pik3cg | 2804 | 0.358 | 0.0602 | No |
| 16 | Notch4 | 2922 | 0.351 | 0.0632 | No |
| 17 | Dusp6 | 2965 | 0.348 | 0.0695 | No |
| 18 | Fn1 | 3190 | 0.333 | 0.0675 | No |
| 19 | Cpm | 3218 | 0.331 | 0.0740 | No |
| 20 | C2 | 3566 | 0.310 | 0.0663 | No |
| 21 | Zeb1 | 4687 | 0.247 | 0.0243 | No |
| 22 | Dock10 | 5110 | 0.228 | 0.0115 | No |
| 23 | Akap10 | 5233 | 0.222 | 0.0114 | No |
| 24 | Phex | 5255 | 0.221 | 0.0156 | No |
| 25 | Prkcd | 5261 | 0.221 | 0.0204 | No |
| 26 | Plaur | 5359 | 0.217 | 0.0213 | No |
| 27 | Lta4h | 5742 | 0.203 | 0.0097 | No |
| 28 | Itgam | 5862 | 0.198 | 0.0091 | No |
| 29 | Apoc1 | 5869 | 0.198 | 0.0134 | No |
| 30 | Src | 6132 | 0.188 | 0.0066 | No |
| 31 | Pcsk9 | 6203 | 0.184 | 0.0078 | No |
| 32 | Cfh | 6382 | 0.178 | 0.0043 | No |
| 33 | Pdp1 | 7231 | 0.147 | -0.0284 | No |
| 34 | Cfb | 7250 | 0.147 | -0.0258 | No |
| 35 | Cd46 | 7272 | 0.146 | -0.0234 | No |
| 36 | Spock2 | 7579 | 0.136 | -0.0333 | No |
| 37 | Sh2b3 | 7606 | 0.135 | -0.0313 | No |
| 38 | Fcer1g | 7672 | 0.133 | -0.0310 | No |
| 39 | Usp8 | 7848 | 0.127 | -0.0356 | No |
| 40 | C3 | 7866 | 0.126 | -0.0334 | No |
| 41 | Pclo | 8050 | 0.119 | -0.0384 | No |
| 42 | Psen1 | 8059 | 0.119 | -0.0361 | No |
| 43 | Fcnb | 8108 | 0.117 | -0.0354 | No |
| 44 | Jak2 | 8166 | 0.115 | -0.0352 | No |
| 45 | Tnfaip3 | 8269 | 0.112 | -0.0370 | No |
| 46 | Dpp4 | 8327 | 0.110 | -0.0369 | No |
| 47 | Gp9 | 8551 | 0.102 | -0.0440 | No |
| 48 | Olr1 | 8611 | 0.100 | -0.0442 | No |
| 49 | Dock4 | 8634 | 0.100 | -0.0429 | No |
| 50 | Cblb | 8756 | 0.096 | -0.0458 | No |
| 51 | Pla2g7 | 8761 | 0.096 | -0.0438 | No |
| 52 | Irf2 | 8841 | 0.094 | -0.0450 | No |
| 53 | Gng2 | 8874 | 0.093 | -0.0442 | No |
| 54 | Lyn | 9107 | 0.085 | -0.0522 | No |
| 55 | Raf1 | 9109 | 0.085 | -0.0502 | No |
| 56 | Ang | 9181 | 0.083 | -0.0514 | No |
| 57 | Pik3ca | 9282 | 0.080 | -0.0538 | No |
| 58 | Was | 9415 | 0.075 | -0.0577 | No |
| 59 | Hspa1a | 9757 | 0.065 | -0.0707 | No |
| 60 | Sirt6 | 9794 | 0.064 | -0.0708 | No |
| 61 | Casp7 | 9927 | 0.059 | -0.0751 | No |
| 62 | Timp2 | 10249 | 0.049 | -0.0876 | No |
| 63 | Me1 | 10348 | 0.047 | -0.0907 | No |
| 64 | Plek | 10917 | 0.029 | -0.1143 | No |
| 65 | Grb2 | 10982 | 0.026 | -0.1164 | No |
| 66 | Atox1 | 11306 | 0.015 | -0.1298 | No |
| 67 | Kynu | 11682 | 0.005 | -0.1457 | No |
| 68 | Ctsh | 12088 | -0.007 | -0.1628 | No |
| 69 | Stx4a | 12096 | -0.007 | -0.1630 | No |
| 70 | Cd36 | 12140 | -0.008 | -0.1646 | No |
| 71 | Casp4 | 12166 | -0.009 | -0.1655 | No |
| 72 | Dgkh | 12196 | -0.010 | -0.1665 | No |
| 73 | Xpnpep1 | 12251 | -0.012 | -0.1685 | No |
| 74 | Usp15 | 12257 | -0.012 | -0.1684 | No |
| 75 | Serpinc1 | 12358 | -0.015 | -0.1723 | No |
| 76 | Casp9 | 12430 | -0.017 | -0.1750 | No |
| 77 | Dyrk2 | 12461 | -0.018 | -0.1758 | No |
| 78 | Cdh13 | 12487 | -0.019 | -0.1764 | No |
| 79 | Kif2a | 12490 | -0.019 | -0.1761 | No |
| 80 | Rnf4 | 12598 | -0.022 | -0.1801 | No |
| 81 | Maff | 12688 | -0.025 | -0.1834 | No |
| 82 | Prcp | 12865 | -0.031 | -0.1902 | No |
| 83 | Prdm4 | 12884 | -0.031 | -0.1902 | No |
| 84 | S100a13 | 12892 | -0.032 | -0.1898 | No |
| 85 | F10 | 12897 | -0.032 | -0.1892 | No |
| 86 | Csrp1 | 13114 | -0.039 | -0.1975 | No |
| 87 | Gnai3 | 13262 | -0.043 | -0.2028 | No |
| 88 | Gnb4 | 13685 | -0.057 | -0.2195 | No |
| 89 | Gmfb | 13707 | -0.058 | -0.2191 | No |
| 90 | Lipa | 14042 | -0.068 | -0.2318 | No |
| 91 | Gpd2 | 14135 | -0.071 | -0.2341 | No |
| 92 | Plg | 14580 | -0.084 | -0.2511 | No |
| 93 | Scg3 | 14940 | -0.095 | -0.2642 | No |
| 94 | Usp14 | 14953 | -0.095 | -0.2625 | No |
| 95 | Msrb1 | 14956 | -0.096 | -0.2604 | No |
| 96 | Dusp5 | 15011 | -0.098 | -0.2605 | No |
| 97 | Rabif | 15015 | -0.098 | -0.2583 | No |
| 98 | F7 | 15300 | -0.108 | -0.2680 | No |
| 99 | Fyn | 15322 | -0.109 | -0.2663 | No |
| 100 | Serping1 | 15571 | -0.118 | -0.2742 | No |
| 101 | Ppp2cb | 15586 | -0.118 | -0.2721 | No |
| 102 | Rbsn | 15696 | -0.122 | -0.2739 | No |
| 103 | Rhog | 15699 | -0.123 | -0.2712 | No |
| 104 | Gnai2 | 15878 | -0.127 | -0.2759 | No |
| 105 | Timp1 | 16047 | -0.132 | -0.2800 | No |
| 106 | Casp3 | 16100 | -0.134 | -0.2791 | No |
| 107 | Usp16 | 16169 | -0.137 | -0.2789 | No |
| 108 | Vcpip1 | 16703 | -0.155 | -0.2981 | No |
| 109 | F5 | 16763 | -0.157 | -0.2970 | No |
| 110 | Fdx1 | 17045 | -0.168 | -0.3051 | No |
| 111 | Psmb9 | 17093 | -0.169 | -0.3032 | No |
| 112 | Mmp15 | 17180 | -0.172 | -0.3029 | No |
| 113 | Hnf4a | 17465 | -0.184 | -0.3108 | No |
| 114 | Kcnip2 | 17530 | -0.187 | -0.3092 | No |
| 115 | S100a9 | 17702 | -0.192 | -0.3121 | No |
| 116 | Tmprss6 | 18236 | -0.213 | -0.3299 | No |
| 117 | Mmp14 | 18336 | -0.217 | -0.3292 | No |
| 118 | Gnb2 | 18478 | -0.224 | -0.3300 | No |
| 119 | C1qc | 18603 | -0.229 | -0.3301 | No |
| 120 | Prep | 18691 | -0.231 | -0.3285 | No |
| 121 | Lgmn | 18702 | -0.231 | -0.3236 | No |
| 122 | Casp1 | 18731 | -0.232 | -0.3194 | No |
| 123 | Ltf | 18761 | -0.234 | -0.3153 | No |
| 124 | Anxa5 | 18861 | -0.239 | -0.3140 | No |
| 125 | Pik3r5 | 19257 | -0.257 | -0.3250 | No |
| 126 | Pfn1 | 19324 | -0.260 | -0.3218 | No |
| 127 | Irf7 | 19598 | -0.276 | -0.3271 | No |
| 128 | Lrp1 | 19716 | -0.281 | -0.3256 | No |
| 129 | Lamp2 | 20277 | -0.308 | -0.3424 | Yes |
| 130 | Ctss | 20305 | -0.309 | -0.3365 | Yes |
| 131 | Pla2g4a | 20501 | -0.321 | -0.3374 | Yes |
| 132 | Mmp8 | 20630 | -0.329 | -0.3353 | Yes |
| 133 | Irf1 | 20700 | -0.333 | -0.3306 | Yes |
| 134 | Rce1 | 20793 | -0.338 | -0.3268 | Yes |
| 135 | Ccl5 | 20833 | -0.341 | -0.3206 | Yes |
| 136 | Gzmk | 21027 | -0.353 | -0.3207 | Yes |
| 137 | Calm1 | 21208 | -0.365 | -0.3200 | Yes |
| 138 | Ctsb | 21210 | -0.366 | -0.3116 | Yes |
| 139 | Zfpm2 | 21222 | -0.366 | -0.3037 | Yes |
| 140 | Cr2 | 21294 | -0.372 | -0.2982 | Yes |
| 141 | Plscr1 | 21385 | -0.379 | -0.2933 | Yes |
| 142 | Klkb1 | 21503 | -0.386 | -0.2894 | Yes |
| 143 | F3 | 21572 | -0.391 | -0.2833 | Yes |
| 144 | C9 | 21577 | -0.391 | -0.2745 | Yes |
| 145 | Dgkg | 21583 | -0.391 | -0.2657 | Yes |
| 146 | Col4a2 | 21946 | -0.421 | -0.2715 | Yes |
| 147 | Tfpi2 | 22017 | -0.428 | -0.2647 | Yes |
| 148 | Dock9 | 22088 | -0.434 | -0.2577 | Yes |
| 149 | Ppp4c | 22091 | -0.434 | -0.2478 | Yes |
| 150 | Ctsd | 22215 | -0.447 | -0.2428 | Yes |
| 151 | Calm3 | 22246 | -0.451 | -0.2337 | Yes |
| 152 | Gata3 | 22447 | -0.473 | -0.2314 | Yes |
| 153 | Actn2 | 22706 | -0.509 | -0.2306 | Yes |
| 154 | Lap3 | 22711 | -0.510 | -0.2191 | Yes |
| 155 | Lck | 22799 | -0.524 | -0.2108 | Yes |
| 156 | Cdk5r1 | 22834 | -0.528 | -0.2001 | Yes |
| 157 | Prss36 | 22898 | -0.541 | -0.1903 | Yes |
| 158 | Car2 | 23015 | -0.561 | -0.1824 | Yes |
| 159 | Cp | 23052 | -0.570 | -0.1708 | Yes |
| 160 | Adam9 | 23128 | -0.589 | -0.1605 | Yes |
| 161 | Gca | 23150 | -0.592 | -0.1478 | Yes |
| 162 | Lgals3 | 23264 | -0.629 | -0.1381 | Yes |
| 163 | Hspa5 | 23275 | -0.632 | -0.1240 | Yes |
| 164 | Pim1 | 23342 | -0.660 | -0.1117 | Yes |
| 165 | Clu | 23389 | -0.683 | -0.0979 | Yes |
| 166 | Ctsc | 23435 | -0.707 | -0.0836 | Yes |
| 167 | Ctsl | 23548 | -0.831 | -0.0693 | Yes |
| 168 | Cebpb | 23551 | -0.834 | -0.0502 | Yes |
| 169 | Rasgrp1 | 23595 | -0.923 | -0.0308 | Yes |
| 170 | Gngt2 | 23624 | -1.395 | 0.0000 | Yes |

