| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group6_versus_Group8.Eosinophil_Pheno.cls #Group6_versus_Group8_repos |
| Phenotype | Eosinophil_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.2178892 |
| Normalized Enrichment Score (NES) | -0.8725027 |
| Nominal p-value | 0.62896824 |
| FDR q-value | 0.8114712 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tk1 | 12 | 1.029 | 0.0194 | No |
| 2 | Tfrc | 93 | 0.770 | 0.0278 | No |
| 3 | Gins1 | 202 | 0.649 | 0.0313 | No |
| 4 | Shmt1 | 278 | 0.610 | 0.0369 | No |
| 5 | Ppp1r8 | 314 | 0.596 | 0.0457 | No |
| 6 | Hells | 355 | 0.581 | 0.0537 | No |
| 7 | Mcm5 | 394 | 0.565 | 0.0617 | No |
| 8 | Dclre1b | 464 | 0.541 | 0.0664 | No |
| 9 | Pole | 481 | 0.536 | 0.0757 | No |
| 10 | Atad2 | 561 | 0.511 | 0.0790 | No |
| 11 | Nop56 | 570 | 0.510 | 0.0884 | No |
| 12 | Hus1 | 622 | 0.495 | 0.0938 | No |
| 13 | Orc6 | 688 | 0.477 | 0.0976 | No |
| 14 | Ak2 | 690 | 0.477 | 0.1070 | No |
| 15 | Prim2 | 754 | 0.459 | 0.1107 | No |
| 16 | Cdc25a | 809 | 0.445 | 0.1148 | No |
| 17 | Mcm2 | 880 | 0.434 | 0.1173 | No |
| 18 | Zw10 | 942 | 0.422 | 0.1204 | No |
| 19 | Rad50 | 959 | 0.420 | 0.1274 | No |
| 20 | Mre11a | 1005 | 0.414 | 0.1317 | No |
| 21 | Psmc3ip | 1100 | 0.404 | 0.1315 | No |
| 22 | Ddx39a | 1125 | 0.401 | 0.1374 | No |
| 23 | Cenpm | 1249 | 0.384 | 0.1343 | No |
| 24 | Nudt21 | 1354 | 0.370 | 0.1325 | No |
| 25 | Lig1 | 1377 | 0.367 | 0.1379 | No |
| 26 | Mad2l1 | 1421 | 0.361 | 0.1413 | No |
| 27 | Cnot9 | 1591 | 0.341 | 0.1333 | No |
| 28 | Rnaseh2a | 1777 | 0.316 | 0.1234 | No |
| 29 | Ube2t | 1832 | 0.312 | 0.1249 | No |
| 30 | Mcm6 | 1858 | 0.309 | 0.1289 | No |
| 31 | Ssrp1 | 1904 | 0.303 | 0.1310 | No |
| 32 | E2f8 | 1939 | 0.300 | 0.1340 | No |
| 33 | Cks1b | 2064 | 0.287 | 0.1289 | No |
| 34 | Dut | 2066 | 0.287 | 0.1345 | No |
| 35 | Slbp | 2143 | 0.280 | 0.1334 | No |
| 36 | Dlgap5 | 2265 | 0.268 | 0.1282 | No |
| 37 | Cbx5 | 2389 | 0.258 | 0.1225 | No |
| 38 | Ing3 | 2473 | 0.250 | 0.1202 | No |
| 39 | H2ax | 2596 | 0.240 | 0.1143 | No |
| 40 | Rrm2 | 2653 | 0.235 | 0.1141 | No |
| 41 | Asf1a | 2664 | 0.234 | 0.1179 | No |
| 42 | Ccne1 | 2763 | 0.229 | 0.1139 | No |
| 43 | Rfc2 | 2822 | 0.223 | 0.1132 | No |
| 44 | Cdkn1b | 2902 | 0.218 | 0.1107 | No |
| 45 | Diaph3 | 2950 | 0.214 | 0.1108 | No |
| 46 | Mybl2 | 2972 | 0.212 | 0.1132 | No |
| 47 | Mthfd2 | 2981 | 0.211 | 0.1167 | No |
| 48 | Pa2g4 | 3152 | 0.197 | 0.1057 | No |
| 49 | Pcna | 3246 | 0.192 | 0.1014 | No |
| 50 | Ezh2 | 3300 | 0.188 | 0.1005 | No |
| 51 | Mlh1 | 3393 | 0.180 | 0.0961 | No |
| 52 | Dck | 3460 | 0.174 | 0.0937 | No |
| 53 | Stag1 | 3602 | 0.163 | 0.0846 | No |
| 54 | Ctcf | 3609 | 0.162 | 0.0873 | No |
| 55 | Dnmt1 | 3625 | 0.162 | 0.0892 | No |
| 56 | Exosc8 | 3678 | 0.157 | 0.0878 | No |
| 57 | Tacc3 | 3708 | 0.155 | 0.0884 | No |
| 58 | Rfc3 | 3777 | 0.150 | 0.0854 | No |
| 59 | Rad1 | 3837 | 0.146 | 0.0831 | No |
| 60 | Mms22l | 3842 | 0.145 | 0.0857 | No |
| 61 | Spc24 | 3884 | 0.142 | 0.0849 | No |
| 62 | Phf5a | 3895 | 0.141 | 0.0869 | No |
| 63 | Donson | 3934 | 0.139 | 0.0863 | No |
| 64 | Brms1l | 3997 | 0.133 | 0.0835 | No |
| 65 | Ilf3 | 4000 | 0.133 | 0.0860 | No |
| 66 | Prps1 | 4055 | 0.129 | 0.0839 | No |
| 67 | Eed | 4061 | 0.129 | 0.0860 | No |
| 68 | Gins3 | 4092 | 0.126 | 0.0859 | No |
| 69 | Chek1 | 4159 | 0.120 | 0.0825 | No |
| 70 | Kif2c | 4214 | 0.116 | 0.0801 | No |
| 71 | Ube2s | 4282 | 0.110 | 0.0764 | No |
| 72 | Bard1 | 4292 | 0.110 | 0.0778 | No |
| 73 | Ppm1d | 4356 | 0.105 | 0.0744 | No |
| 74 | Mcm4 | 4499 | 0.095 | 0.0638 | No |
| 75 | Tipin | 4531 | 0.092 | 0.0630 | No |
| 76 | Nap1l1 | 4568 | 0.090 | 0.0616 | No |
| 77 | Suv39h1 | 4679 | 0.082 | 0.0536 | No |
| 78 | Ccp110 | 4699 | 0.081 | 0.0535 | No |
| 79 | Pold1 | 4992 | 0.059 | 0.0291 | No |
| 80 | Eif2s1 | 5023 | 0.056 | 0.0276 | No |
| 81 | Pds5b | 5109 | 0.051 | 0.0212 | No |
| 82 | Pms2 | 5137 | 0.050 | 0.0198 | No |
| 83 | Spc25 | 5154 | 0.048 | 0.0194 | No |
| 84 | Cse1l | 5233 | 0.043 | 0.0134 | No |
| 85 | Srsf2 | 5248 | 0.042 | 0.0130 | No |
| 86 | Tbrg4 | 5470 | 0.024 | -0.0058 | No |
| 87 | Stmn1 | 5560 | 0.019 | -0.0133 | No |
| 88 | Spag5 | 5563 | 0.019 | -0.0131 | No |
| 89 | Lbr | 5621 | 0.014 | -0.0178 | No |
| 90 | Nup107 | 5727 | 0.007 | -0.0268 | No |
| 91 | Dctpp1 | 5830 | 0.001 | -0.0357 | No |
| 92 | Trip13 | 5844 | 0.000 | -0.0369 | No |
| 93 | Cdca8 | 6019 | -0.003 | -0.0521 | No |
| 94 | Gspt1 | 6148 | -0.013 | -0.0630 | No |
| 95 | Lyar | 6188 | -0.015 | -0.0661 | No |
| 96 | Ung | 6206 | -0.017 | -0.0673 | No |
| 97 | Asf1b | 6217 | -0.018 | -0.0678 | No |
| 98 | Brca2 | 6234 | -0.020 | -0.0688 | No |
| 99 | Myc | 6389 | -0.031 | -0.0816 | No |
| 100 | Lmnb1 | 6493 | -0.038 | -0.0899 | No |
| 101 | Prkdc | 6564 | -0.044 | -0.0952 | No |
| 102 | Wdr90 | 6588 | -0.046 | -0.0963 | No |
| 103 | Chek2 | 6609 | -0.047 | -0.0971 | No |
| 104 | Hmmr | 6686 | -0.052 | -0.1027 | No |
| 105 | Ipo7 | 6711 | -0.054 | -0.1037 | No |
| 106 | Rpa2 | 6762 | -0.059 | -0.1069 | No |
| 107 | Smc6 | 6832 | -0.065 | -0.1117 | No |
| 108 | Rbbp7 | 6939 | -0.072 | -0.1195 | No |
| 109 | Ubr7 | 7321 | -0.101 | -0.1509 | No |
| 110 | Nme1 | 7386 | -0.105 | -0.1544 | No |
| 111 | Hmgb3 | 7453 | -0.111 | -0.1580 | No |
| 112 | Xpo1 | 7468 | -0.113 | -0.1569 | No |
| 113 | Dscc1 | 7473 | -0.113 | -0.1550 | No |
| 114 | Tra2b | 7524 | -0.116 | -0.1571 | No |
| 115 | Cdk1 | 7541 | -0.118 | -0.1562 | No |
| 116 | Pan2 | 7543 | -0.119 | -0.1539 | No |
| 117 | Xrcc6 | 7590 | -0.122 | -0.1555 | No |
| 118 | Rad21 | 7635 | -0.125 | -0.1568 | No |
| 119 | Plk1 | 7667 | -0.127 | -0.1570 | No |
| 120 | Rad51ap1 | 7687 | -0.128 | -0.1561 | No |
| 121 | Brca1 | 7688 | -0.128 | -0.1536 | No |
| 122 | Paics | 7689 | -0.128 | -0.1510 | No |
| 123 | Rpa1 | 7718 | -0.130 | -0.1509 | No |
| 124 | Trp53 | 7750 | -0.134 | -0.1509 | No |
| 125 | Rpa3 | 7779 | -0.137 | -0.1506 | No |
| 126 | Cdkn2c | 7906 | -0.147 | -0.1588 | No |
| 127 | Kif4 | 7945 | -0.149 | -0.1591 | No |
| 128 | Nup205 | 7969 | -0.151 | -0.1581 | No |
| 129 | Depdc1a | 8007 | -0.153 | -0.1583 | No |
| 130 | Rfc1 | 8014 | -0.154 | -0.1558 | No |
| 131 | Snrpb | 8094 | -0.160 | -0.1595 | No |
| 132 | Psip1 | 8133 | -0.163 | -0.1596 | No |
| 133 | Pnn | 8163 | -0.166 | -0.1588 | No |
| 134 | Timeless | 8189 | -0.168 | -0.1577 | No |
| 135 | Anp32e | 8261 | -0.173 | -0.1605 | No |
| 136 | Pold3 | 8272 | -0.174 | -0.1579 | No |
| 137 | Orc2 | 8306 | -0.177 | -0.1572 | No |
| 138 | Espl1 | 8344 | -0.180 | -0.1569 | No |
| 139 | Nup153 | 8478 | -0.194 | -0.1647 | No |
| 140 | H2az1 | 8501 | -0.195 | -0.1627 | No |
| 141 | Cdca3 | 8534 | -0.198 | -0.1616 | No |
| 142 | Cks2 | 8537 | -0.198 | -0.1578 | No |
| 143 | Bub1b | 8730 | -0.215 | -0.1703 | No |
| 144 | Nbn | 8771 | -0.219 | -0.1695 | No |
| 145 | Lsm8 | 9178 | -0.245 | -0.2001 | No |
| 146 | Msh2 | 9273 | -0.253 | -0.2033 | No |
| 147 | Usp1 | 9276 | -0.254 | -0.1985 | No |
| 148 | Syncrip | 9283 | -0.255 | -0.1939 | No |
| 149 | Nasp | 9334 | -0.260 | -0.1931 | No |
| 150 | Cdc25b | 9618 | -0.292 | -0.2121 | Yes |
| 151 | Cit | 9664 | -0.297 | -0.2101 | Yes |
| 152 | Smc3 | 9668 | -0.297 | -0.2044 | Yes |
| 153 | Luc7l3 | 9674 | -0.298 | -0.1990 | Yes |
| 154 | Aurka | 9767 | -0.308 | -0.2009 | Yes |
| 155 | Tubb5 | 9865 | -0.317 | -0.2030 | Yes |
| 156 | Srsf1 | 9952 | -0.328 | -0.2040 | Yes |
| 157 | Plk4 | 10025 | -0.334 | -0.2037 | Yes |
| 158 | Smc4 | 10034 | -0.335 | -0.1977 | Yes |
| 159 | Ran | 10077 | -0.342 | -0.1946 | Yes |
| 160 | Racgap1 | 10127 | -0.347 | -0.1919 | Yes |
| 161 | Kif18b | 10163 | -0.353 | -0.1880 | Yes |
| 162 | Gins4 | 10241 | -0.365 | -0.1874 | Yes |
| 163 | Hnrnpd | 10254 | -0.366 | -0.1812 | Yes |
| 164 | Top2a | 10265 | -0.368 | -0.1748 | Yes |
| 165 | Tmpo | 10350 | -0.381 | -0.1745 | Yes |
| 166 | Wee1 | 10379 | -0.386 | -0.1693 | Yes |
| 167 | Kif22 | 10435 | -0.393 | -0.1663 | Yes |
| 168 | Mki67 | 10454 | -0.397 | -0.1599 | Yes |
| 169 | Ranbp1 | 10456 | -0.397 | -0.1521 | Yes |
| 170 | Pola2 | 10480 | -0.402 | -0.1461 | Yes |
| 171 | Birc5 | 10489 | -0.403 | -0.1388 | Yes |
| 172 | Smc1a | 10621 | -0.422 | -0.1419 | Yes |
| 173 | Jpt1 | 10625 | -0.423 | -0.1337 | Yes |
| 174 | Hmgb2 | 10682 | -0.433 | -0.1300 | Yes |
| 175 | Pole4 | 10813 | -0.453 | -0.1323 | Yes |
| 176 | Cenpe | 10822 | -0.455 | -0.1240 | Yes |
| 177 | Ncapd2 | 10886 | -0.467 | -0.1202 | Yes |
| 178 | Cdc20 | 10914 | -0.472 | -0.1131 | Yes |
| 179 | Tubg1 | 10945 | -0.476 | -0.1063 | Yes |
| 180 | Mcm3 | 11037 | -0.497 | -0.1044 | Yes |
| 181 | Ccnb2 | 11098 | -0.516 | -0.0993 | Yes |
| 182 | Cdkn1a | 11114 | -0.522 | -0.0903 | Yes |
| 183 | Pttg1 | 11130 | -0.527 | -0.0811 | Yes |
| 184 | Dek | 11161 | -0.536 | -0.0730 | Yes |
| 185 | Pold2 | 11164 | -0.537 | -0.0625 | Yes |
| 186 | Mcm7 | 11266 | -0.578 | -0.0598 | Yes |
| 187 | Cdkn3 | 11271 | -0.580 | -0.0486 | Yes |
| 188 | Rad51c | 11326 | -0.600 | -0.0414 | Yes |
| 189 | Tcf19 | 11370 | -0.625 | -0.0327 | Yes |
| 190 | Aurkb | 11387 | -0.635 | -0.0214 | Yes |
| 191 | Cdk4 | 11438 | -0.670 | -0.0125 | Yes |
| 192 | Nolc1 | 11450 | -0.681 | 0.0001 | Yes |
| 193 | Melk | 11455 | -0.687 | 0.0135 | Yes |

