| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group3_versus_Group4.Eosinophil_Pheno.cls #Group3_versus_Group4_repos |
| Phenotype | Eosinophil_Pheno.cls#Group3_versus_Group4_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.43796203 |
| Normalized Enrichment Score (NES) | 1.4739391 |
| Nominal p-value | 0.13664596 |
| FDR q-value | 0.1668315 |
| FWER p-Value | 0.357 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Aurka | 30 | 1.513 | 0.0203 | Yes |
| 2 | Spc25 | 60 | 1.294 | 0.0374 | Yes |
| 3 | Xrcc6 | 85 | 1.206 | 0.0536 | Yes |
| 4 | Eed | 98 | 1.191 | 0.0707 | Yes |
| 5 | Pole | 124 | 1.124 | 0.0855 | Yes |
| 6 | Cdc20 | 141 | 1.092 | 0.1007 | Yes |
| 7 | Rfc3 | 151 | 1.078 | 0.1163 | Yes |
| 8 | Plk1 | 244 | 0.967 | 0.1229 | Yes |
| 9 | Tubb5 | 288 | 0.926 | 0.1332 | Yes |
| 10 | Rad1 | 341 | 0.887 | 0.1421 | Yes |
| 11 | Brca2 | 359 | 0.872 | 0.1539 | Yes |
| 12 | Mcm4 | 377 | 0.860 | 0.1654 | Yes |
| 13 | Kif4 | 425 | 0.829 | 0.1739 | Yes |
| 14 | Cdca8 | 455 | 0.815 | 0.1837 | Yes |
| 15 | Pola2 | 476 | 0.798 | 0.1941 | Yes |
| 16 | Ncapd2 | 501 | 0.785 | 0.2039 | Yes |
| 17 | Tcf19 | 590 | 0.748 | 0.2076 | Yes |
| 18 | Cdc25b | 616 | 0.737 | 0.2166 | Yes |
| 19 | Psip1 | 660 | 0.725 | 0.2238 | Yes |
| 20 | Aurkb | 728 | 0.706 | 0.2286 | Yes |
| 21 | Dlgap5 | 753 | 0.697 | 0.2371 | Yes |
| 22 | Tacc3 | 777 | 0.691 | 0.2456 | Yes |
| 23 | Depdc1a | 806 | 0.684 | 0.2535 | Yes |
| 24 | Mki67 | 819 | 0.680 | 0.2628 | Yes |
| 25 | Smc4 | 848 | 0.673 | 0.2706 | Yes |
| 26 | Ccp110 | 869 | 0.669 | 0.2790 | Yes |
| 27 | Kif22 | 912 | 0.657 | 0.2853 | Yes |
| 28 | Hmmr | 993 | 0.633 | 0.2879 | Yes |
| 29 | Cit | 1014 | 0.626 | 0.2956 | Yes |
| 30 | Hmgb2 | 1067 | 0.612 | 0.3003 | Yes |
| 31 | Tmpo | 1125 | 0.599 | 0.3044 | Yes |
| 32 | Cdc25a | 1154 | 0.594 | 0.3110 | Yes |
| 33 | Kif2c | 1182 | 0.588 | 0.3176 | Yes |
| 34 | Kif18b | 1198 | 0.586 | 0.3252 | Yes |
| 35 | Cdkn2c | 1199 | 0.586 | 0.3341 | Yes |
| 36 | Lmnb1 | 1245 | 0.574 | 0.3388 | Yes |
| 37 | Mre11a | 1247 | 0.573 | 0.3474 | Yes |
| 38 | Dctpp1 | 1253 | 0.572 | 0.3557 | Yes |
| 39 | Pms2 | 1268 | 0.570 | 0.3631 | Yes |
| 40 | Spag5 | 1284 | 0.567 | 0.3704 | Yes |
| 41 | Shmt1 | 1300 | 0.562 | 0.3776 | Yes |
| 42 | Cdk1 | 1342 | 0.553 | 0.3824 | Yes |
| 43 | Donson | 1372 | 0.547 | 0.3882 | Yes |
| 44 | Cks2 | 1396 | 0.542 | 0.3944 | Yes |
| 45 | Prim2 | 1525 | 0.522 | 0.3911 | Yes |
| 46 | Rpa2 | 1555 | 0.519 | 0.3965 | Yes |
| 47 | Cenpe | 1558 | 0.519 | 0.4042 | Yes |
| 48 | Espl1 | 1564 | 0.518 | 0.4116 | Yes |
| 49 | Mad2l1 | 1597 | 0.511 | 0.4166 | Yes |
| 50 | Zw10 | 1717 | 0.492 | 0.4136 | Yes |
| 51 | Melk | 1723 | 0.491 | 0.4206 | Yes |
| 52 | Pold1 | 1784 | 0.479 | 0.4226 | Yes |
| 53 | Bard1 | 1844 | 0.470 | 0.4246 | Yes |
| 54 | Rad21 | 1859 | 0.468 | 0.4305 | Yes |
| 55 | Ube2t | 2178 | 0.418 | 0.4090 | Yes |
| 56 | Diaph3 | 2243 | 0.410 | 0.4096 | Yes |
| 57 | Ing3 | 2317 | 0.402 | 0.4093 | Yes |
| 58 | Top2a | 2376 | 0.390 | 0.4101 | Yes |
| 59 | Dut | 2379 | 0.389 | 0.4159 | Yes |
| 60 | Gins3 | 2382 | 0.389 | 0.4216 | Yes |
| 61 | Nap1l1 | 2385 | 0.389 | 0.4273 | Yes |
| 62 | Jpt1 | 2425 | 0.385 | 0.4298 | Yes |
| 63 | Rad51ap1 | 2492 | 0.376 | 0.4297 | Yes |
| 64 | Brca1 | 2550 | 0.372 | 0.4303 | Yes |
| 65 | Srsf1 | 2605 | 0.366 | 0.4312 | Yes |
| 66 | Lyar | 2696 | 0.354 | 0.4287 | Yes |
| 67 | Anp32e | 2737 | 0.352 | 0.4305 | Yes |
| 68 | Ssrp1 | 2745 | 0.351 | 0.4352 | Yes |
| 69 | Rrm2 | 2775 | 0.348 | 0.4380 | Yes |
| 70 | Plk4 | 2893 | 0.336 | 0.4328 | No |
| 71 | Spc24 | 3013 | 0.323 | 0.4273 | No |
| 72 | Syncrip | 3045 | 0.319 | 0.4294 | No |
| 73 | Rbbp7 | 3051 | 0.318 | 0.4338 | No |
| 74 | Wdr90 | 3065 | 0.317 | 0.4375 | No |
| 75 | Ipo7 | 3162 | 0.306 | 0.4337 | No |
| 76 | Asf1b | 3339 | 0.291 | 0.4227 | No |
| 77 | Nop56 | 3351 | 0.289 | 0.4261 | No |
| 78 | Rad50 | 3427 | 0.282 | 0.4239 | No |
| 79 | Ung | 3480 | 0.275 | 0.4235 | No |
| 80 | Nme1 | 3536 | 0.269 | 0.4227 | No |
| 81 | Nasp | 3615 | 0.263 | 0.4199 | No |
| 82 | Paics | 3691 | 0.254 | 0.4172 | No |
| 83 | Rad51c | 3978 | 0.221 | 0.3955 | No |
| 84 | Cdkn1a | 4009 | 0.220 | 0.3962 | No |
| 85 | Ezh2 | 4077 | 0.213 | 0.3936 | No |
| 86 | Nup153 | 4080 | 0.212 | 0.3966 | No |
| 87 | Mthfd2 | 4083 | 0.212 | 0.3996 | No |
| 88 | E2f8 | 4129 | 0.206 | 0.3988 | No |
| 89 | Nudt21 | 4179 | 0.202 | 0.3976 | No |
| 90 | Mlh1 | 4309 | 0.189 | 0.3892 | No |
| 91 | Cdk4 | 4330 | 0.188 | 0.3903 | No |
| 92 | Dclre1b | 4429 | 0.180 | 0.3844 | No |
| 93 | Slbp | 4442 | 0.179 | 0.3861 | No |
| 94 | Mcm6 | 4494 | 0.175 | 0.3843 | No |
| 95 | Mybl2 | 4522 | 0.172 | 0.3845 | No |
| 96 | Dek | 4590 | 0.164 | 0.3811 | No |
| 97 | Cse1l | 4654 | 0.159 | 0.3780 | No |
| 98 | Cenpm | 4661 | 0.158 | 0.3799 | No |
| 99 | Tipin | 4685 | 0.156 | 0.3803 | No |
| 100 | Lbr | 4698 | 0.154 | 0.3816 | No |
| 101 | Pold2 | 4703 | 0.154 | 0.3835 | No |
| 102 | Hus1 | 4760 | 0.150 | 0.3809 | No |
| 103 | Tk1 | 4841 | 0.143 | 0.3761 | No |
| 104 | Atad2 | 4895 | 0.137 | 0.3735 | No |
| 105 | Racgap1 | 5242 | 0.110 | 0.3449 | No |
| 106 | Gins1 | 5312 | 0.104 | 0.3404 | No |
| 107 | Smc6 | 5332 | 0.102 | 0.3403 | No |
| 108 | Ilf3 | 5380 | 0.098 | 0.3377 | No |
| 109 | Cnot9 | 5448 | 0.092 | 0.3332 | No |
| 110 | Trip13 | 5546 | 0.082 | 0.3259 | No |
| 111 | H2ax | 5581 | 0.079 | 0.3242 | No |
| 112 | Usp1 | 5746 | 0.064 | 0.3108 | No |
| 113 | H2az1 | 5758 | 0.063 | 0.3108 | No |
| 114 | Ranbp1 | 5804 | 0.062 | 0.3078 | No |
| 115 | Srsf2 | 5843 | 0.058 | 0.3053 | No |
| 116 | Pnn | 5848 | 0.058 | 0.3058 | No |
| 117 | Lsm8 | 5907 | 0.051 | 0.3015 | No |
| 118 | Pold3 | 5924 | 0.050 | 0.3009 | No |
| 119 | Lig1 | 5941 | 0.049 | 0.3002 | No |
| 120 | Cbx5 | 5942 | 0.049 | 0.3010 | No |
| 121 | Cks1b | 5955 | 0.048 | 0.3007 | No |
| 122 | Mms22l | 5984 | 0.045 | 0.2989 | No |
| 123 | Ppp1r8 | 6005 | 0.042 | 0.2978 | No |
| 124 | Tbrg4 | 6087 | 0.037 | 0.2912 | No |
| 125 | Mcm2 | 6094 | 0.036 | 0.2913 | No |
| 126 | Chek2 | 6110 | 0.035 | 0.2905 | No |
| 127 | Chek1 | 6164 | 0.031 | 0.2863 | No |
| 128 | Hells | 6183 | 0.030 | 0.2852 | No |
| 129 | Prps1 | 6208 | 0.027 | 0.2835 | No |
| 130 | Mcm7 | 6249 | 0.023 | 0.2803 | No |
| 131 | Ctcf | 6309 | 0.019 | 0.2755 | No |
| 132 | Birc5 | 6423 | 0.009 | 0.2657 | No |
| 133 | Hmgb3 | 6438 | 0.008 | 0.2646 | No |
| 134 | Nbn | 6503 | 0.004 | 0.2591 | No |
| 135 | Mcm5 | 6615 | -0.001 | 0.2493 | No |
| 136 | Gins4 | 6668 | -0.006 | 0.2449 | No |
| 137 | Rpa3 | 6717 | -0.010 | 0.2408 | No |
| 138 | Tra2b | 6718 | -0.010 | 0.2410 | No |
| 139 | Bub1b | 6827 | -0.019 | 0.2318 | No |
| 140 | Hnrnpd | 6838 | -0.020 | 0.2312 | No |
| 141 | Ccnb2 | 6963 | -0.032 | 0.2208 | No |
| 142 | Luc7l3 | 7123 | -0.045 | 0.2076 | No |
| 143 | Ppm1d | 7151 | -0.047 | 0.2059 | No |
| 144 | Stmn1 | 7160 | -0.049 | 0.2060 | No |
| 145 | Cdca3 | 7231 | -0.055 | 0.2007 | No |
| 146 | Prkdc | 7355 | -0.063 | 0.1909 | No |
| 147 | Mcm3 | 7388 | -0.066 | 0.1891 | No |
| 148 | Stag1 | 7412 | -0.068 | 0.1881 | No |
| 149 | Tubg1 | 7423 | -0.069 | 0.1883 | No |
| 150 | Snrpb | 7495 | -0.075 | 0.1832 | No |
| 151 | Pole4 | 7551 | -0.078 | 0.1796 | No |
| 152 | Timeless | 7580 | -0.080 | 0.1783 | No |
| 153 | Nup107 | 7889 | -0.105 | 0.1529 | No |
| 154 | Rpa1 | 7964 | -0.111 | 0.1482 | No |
| 155 | Cdkn1b | 8039 | -0.118 | 0.1435 | No |
| 156 | Phf5a | 8056 | -0.120 | 0.1439 | No |
| 157 | Pcna | 8060 | -0.120 | 0.1454 | No |
| 158 | Myc | 8109 | -0.124 | 0.1431 | No |
| 159 | Gspt1 | 8281 | -0.139 | 0.1303 | No |
| 160 | Rfc2 | 8312 | -0.142 | 0.1298 | No |
| 161 | Ak2 | 8470 | -0.154 | 0.1184 | No |
| 162 | Asf1a | 8504 | -0.157 | 0.1179 | No |
| 163 | Smc3 | 8527 | -0.159 | 0.1184 | No |
| 164 | Orc2 | 8709 | -0.175 | 0.1052 | No |
| 165 | Psmc3ip | 8715 | -0.175 | 0.1074 | No |
| 166 | Nolc1 | 8764 | -0.180 | 0.1059 | No |
| 167 | Ran | 8890 | -0.190 | 0.0978 | No |
| 168 | Exosc8 | 8926 | -0.193 | 0.0977 | No |
| 169 | Nup205 | 9232 | -0.222 | 0.0744 | No |
| 170 | Smc1a | 9234 | -0.223 | 0.0776 | No |
| 171 | Cdkn3 | 9237 | -0.223 | 0.0809 | No |
| 172 | Pttg1 | 9466 | -0.244 | 0.0646 | No |
| 173 | Ubr7 | 9557 | -0.253 | 0.0605 | No |
| 174 | Brms1l | 9729 | -0.269 | 0.0497 | No |
| 175 | Pds5b | 9809 | -0.276 | 0.0469 | No |
| 176 | Rnaseh2a | 9862 | -0.282 | 0.0466 | No |
| 177 | Eif2s1 | 9905 | -0.287 | 0.0473 | No |
| 178 | Xpo1 | 10050 | -0.299 | 0.0392 | No |
| 179 | Trp53 | 10064 | -0.300 | 0.0427 | No |
| 180 | Dnmt1 | 10152 | -0.310 | 0.0398 | No |
| 181 | Tfrc | 10270 | -0.324 | 0.0344 | No |
| 182 | Orc6 | 10347 | -0.333 | 0.0328 | No |
| 183 | Suv39h1 | 10484 | -0.352 | 0.0263 | No |
| 184 | Dck | 10585 | -0.366 | 0.0231 | No |
| 185 | Msh2 | 10587 | -0.367 | 0.0285 | No |
| 186 | Dscc1 | 10973 | -0.433 | 0.0014 | No |
| 187 | Ddx39a | 11064 | -0.453 | 0.0004 | No |
| 188 | Wee1 | 11103 | -0.464 | 0.0041 | No |
| 189 | Pan2 | 11143 | -0.475 | 0.0079 | No |
| 190 | Ccne1 | 11182 | -0.488 | 0.0120 | No |
| 191 | Rfc1 | 11260 | -0.522 | 0.0132 | No |
| 192 | Ube2s | 11297 | -0.539 | 0.0182 | No |
| 193 | Pa2g4 | 11415 | -0.596 | 0.0170 | No |

