| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group2_versus_Group4.Eosinophil_Pheno.cls #Group2_versus_Group4_repos |
| Phenotype | Eosinophil_Pheno.cls#Group2_versus_Group4_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.4198231 |
| Normalized Enrichment Score (NES) | 1.5145195 |
| Nominal p-value | 0.0831643 |
| FDR q-value | 0.11889774 |
| FWER p-Value | 0.281 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Dlgap5 | 1 | 1.675 | 0.0259 | Yes |
| 2 | Aurka | 16 | 1.248 | 0.0441 | Yes |
| 3 | Kif4 | 42 | 1.102 | 0.0590 | Yes |
| 4 | Mad2l1 | 51 | 1.076 | 0.0751 | Yes |
| 5 | Spc25 | 99 | 0.947 | 0.0857 | Yes |
| 6 | Hmgb2 | 103 | 0.934 | 0.0999 | Yes |
| 7 | Kif18b | 104 | 0.932 | 0.1144 | Yes |
| 8 | Tacc3 | 111 | 0.926 | 0.1283 | Yes |
| 9 | Ncapd2 | 121 | 0.916 | 0.1417 | Yes |
| 10 | Plk4 | 138 | 0.890 | 0.1541 | Yes |
| 11 | Depdc1a | 149 | 0.875 | 0.1668 | Yes |
| 12 | Kif2c | 156 | 0.868 | 0.1798 | Yes |
| 13 | Pole | 159 | 0.865 | 0.1931 | Yes |
| 14 | Eed | 161 | 0.859 | 0.2063 | Yes |
| 15 | Ccp110 | 238 | 0.785 | 0.2119 | Yes |
| 16 | Cks2 | 275 | 0.756 | 0.2205 | Yes |
| 17 | Smc4 | 304 | 0.741 | 0.2295 | Yes |
| 18 | Anp32e | 306 | 0.740 | 0.2409 | Yes |
| 19 | Cenpe | 319 | 0.734 | 0.2513 | Yes |
| 20 | Mki67 | 322 | 0.732 | 0.2625 | Yes |
| 21 | Spag5 | 326 | 0.730 | 0.2736 | Yes |
| 22 | Rad21 | 341 | 0.724 | 0.2836 | Yes |
| 23 | Brca2 | 345 | 0.722 | 0.2946 | Yes |
| 24 | Hmmr | 404 | 0.694 | 0.3003 | Yes |
| 25 | Rfc3 | 443 | 0.680 | 0.3075 | Yes |
| 26 | Zw10 | 451 | 0.676 | 0.3174 | Yes |
| 27 | Cit | 467 | 0.667 | 0.3264 | Yes |
| 28 | Cdca8 | 561 | 0.630 | 0.3281 | Yes |
| 29 | Psip1 | 568 | 0.628 | 0.3373 | Yes |
| 30 | Cdk1 | 586 | 0.621 | 0.3455 | Yes |
| 31 | Brca1 | 699 | 0.580 | 0.3447 | Yes |
| 32 | Mcm4 | 707 | 0.578 | 0.3531 | Yes |
| 33 | Kif22 | 751 | 0.570 | 0.3581 | Yes |
| 34 | Plk1 | 781 | 0.564 | 0.3644 | Yes |
| 35 | Spc24 | 814 | 0.558 | 0.3702 | Yes |
| 36 | Cdc25a | 853 | 0.551 | 0.3754 | Yes |
| 37 | Rbbp7 | 885 | 0.545 | 0.3812 | Yes |
| 38 | Cdkn2c | 906 | 0.540 | 0.3878 | Yes |
| 39 | Cdc25b | 907 | 0.539 | 0.3962 | Yes |
| 40 | Tmpo | 1011 | 0.519 | 0.3953 | Yes |
| 41 | Prim2 | 1047 | 0.512 | 0.4002 | Yes |
| 42 | Aurkb | 1050 | 0.512 | 0.4079 | Yes |
| 43 | Lmnb1 | 1184 | 0.490 | 0.4039 | Yes |
| 44 | Nasp | 1223 | 0.483 | 0.4081 | Yes |
| 45 | Cdkn1b | 1341 | 0.465 | 0.4050 | Yes |
| 46 | Top2a | 1343 | 0.464 | 0.4122 | Yes |
| 47 | Ssrp1 | 1374 | 0.459 | 0.4167 | Yes |
| 48 | Syncrip | 1419 | 0.451 | 0.4198 | Yes |
| 49 | Diaph3 | 1590 | 0.427 | 0.4116 | No |
| 50 | Pold1 | 1788 | 0.401 | 0.4005 | No |
| 51 | Donson | 1824 | 0.397 | 0.4037 | No |
| 52 | Cdc20 | 1858 | 0.391 | 0.4068 | No |
| 53 | Prkdc | 1866 | 0.391 | 0.4123 | No |
| 54 | Ak2 | 1952 | 0.383 | 0.4108 | No |
| 55 | Racgap1 | 2018 | 0.375 | 0.4109 | No |
| 56 | Xrcc6 | 2266 | 0.344 | 0.3946 | No |
| 57 | Rad1 | 2371 | 0.332 | 0.3907 | No |
| 58 | Tcf19 | 2394 | 0.329 | 0.3939 | No |
| 59 | Rad51c | 2497 | 0.319 | 0.3899 | No |
| 60 | Espl1 | 2572 | 0.309 | 0.3882 | No |
| 61 | Melk | 2678 | 0.297 | 0.3836 | No |
| 62 | Dctpp1 | 2847 | 0.282 | 0.3733 | No |
| 63 | Srsf1 | 2914 | 0.274 | 0.3717 | No |
| 64 | Lig1 | 2998 | 0.265 | 0.3686 | No |
| 65 | Tubb5 | 2999 | 0.265 | 0.3727 | No |
| 66 | Rad51ap1 | 3018 | 0.264 | 0.3753 | No |
| 67 | Cbx5 | 3154 | 0.252 | 0.3673 | No |
| 68 | Pms2 | 3238 | 0.242 | 0.3638 | No |
| 69 | Pola2 | 3332 | 0.231 | 0.3593 | No |
| 70 | E2f8 | 3385 | 0.225 | 0.3582 | No |
| 71 | Lsm8 | 3389 | 0.225 | 0.3614 | No |
| 72 | Dclre1b | 3437 | 0.219 | 0.3607 | No |
| 73 | Rrm2 | 3836 | 0.191 | 0.3288 | No |
| 74 | Pold3 | 3855 | 0.190 | 0.3302 | No |
| 75 | Ipo7 | 3871 | 0.188 | 0.3318 | No |
| 76 | Nap1l1 | 3901 | 0.185 | 0.3322 | No |
| 77 | Paics | 3942 | 0.184 | 0.3315 | No |
| 78 | Ing3 | 3979 | 0.179 | 0.3311 | No |
| 79 | Stmn1 | 4037 | 0.173 | 0.3288 | No |
| 80 | Ezh2 | 4045 | 0.172 | 0.3309 | No |
| 81 | Pttg1 | 4093 | 0.168 | 0.3294 | No |
| 82 | Ppm1d | 4106 | 0.167 | 0.3309 | No |
| 83 | Cks1b | 4164 | 0.162 | 0.3285 | No |
| 84 | Ilf3 | 4207 | 0.157 | 0.3272 | No |
| 85 | Ube2t | 4254 | 0.153 | 0.3256 | No |
| 86 | Slbp | 4258 | 0.153 | 0.3277 | No |
| 87 | Lbr | 4262 | 0.153 | 0.3298 | No |
| 88 | Bard1 | 4344 | 0.145 | 0.3250 | No |
| 89 | Shmt1 | 4394 | 0.139 | 0.3228 | No |
| 90 | Dut | 4411 | 0.137 | 0.3235 | No |
| 91 | Bub1b | 4453 | 0.132 | 0.3220 | No |
| 92 | Nup107 | 4614 | 0.121 | 0.3099 | No |
| 93 | Ppp1r8 | 4646 | 0.118 | 0.3090 | No |
| 94 | Tipin | 4660 | 0.117 | 0.3097 | No |
| 95 | H2az1 | 4672 | 0.116 | 0.3105 | No |
| 96 | Birc5 | 4724 | 0.110 | 0.3077 | No |
| 97 | Mlh1 | 4840 | 0.099 | 0.2992 | No |
| 98 | Hmgb3 | 4895 | 0.095 | 0.2959 | No |
| 99 | Tk1 | 4937 | 0.092 | 0.2938 | No |
| 100 | Mthfd2 | 5067 | 0.082 | 0.2838 | No |
| 101 | Mcm7 | 5155 | 0.074 | 0.2773 | No |
| 102 | Pcna | 5188 | 0.071 | 0.2756 | No |
| 103 | Smc3 | 5250 | 0.068 | 0.2713 | No |
| 104 | Atad2 | 5285 | 0.065 | 0.2693 | No |
| 105 | Mybl2 | 5419 | 0.053 | 0.2585 | No |
| 106 | Asf1a | 5486 | 0.047 | 0.2534 | No |
| 107 | Mre11a | 5553 | 0.041 | 0.2483 | No |
| 108 | Asf1b | 5688 | 0.028 | 0.2370 | No |
| 109 | Lyar | 5758 | 0.022 | 0.2313 | No |
| 110 | Rpa3 | 5788 | 0.019 | 0.2291 | No |
| 111 | H2ax | 5807 | 0.018 | 0.2278 | No |
| 112 | Ccnb2 | 5810 | 0.018 | 0.2279 | No |
| 113 | Wdr90 | 5849 | 0.014 | 0.2248 | No |
| 114 | Dek | 5897 | 0.011 | 0.2208 | No |
| 115 | Trip13 | 5917 | 0.009 | 0.2193 | No |
| 116 | Pole4 | 5994 | 0.003 | 0.2127 | No |
| 117 | Cdkn1a | 6033 | 0.000 | 0.2093 | No |
| 118 | Hus1 | 6087 | -0.000 | 0.2047 | No |
| 119 | Ung | 6118 | -0.002 | 0.2021 | No |
| 120 | Cdk4 | 6143 | -0.004 | 0.2001 | No |
| 121 | Rad50 | 6157 | -0.005 | 0.1990 | No |
| 122 | Rpa1 | 6192 | -0.008 | 0.1962 | No |
| 123 | Dnmt1 | 6341 | -0.020 | 0.1835 | No |
| 124 | Phf5a | 6457 | -0.030 | 0.1739 | No |
| 125 | Eif2s1 | 6479 | -0.032 | 0.1726 | No |
| 126 | Smc6 | 6494 | -0.033 | 0.1719 | No |
| 127 | Hnrnpd | 6526 | -0.036 | 0.1697 | No |
| 128 | Cnot9 | 6532 | -0.036 | 0.1698 | No |
| 129 | Pan2 | 6628 | -0.044 | 0.1622 | No |
| 130 | Rpa2 | 6647 | -0.046 | 0.1613 | No |
| 131 | Chek1 | 6756 | -0.051 | 0.1527 | No |
| 132 | Nup153 | 6864 | -0.061 | 0.1442 | No |
| 133 | Smc1a | 6929 | -0.065 | 0.1396 | No |
| 134 | Ddx39a | 6951 | -0.067 | 0.1388 | No |
| 135 | Gins1 | 6983 | -0.069 | 0.1372 | No |
| 136 | Nudt21 | 7144 | -0.081 | 0.1244 | No |
| 137 | Ranbp1 | 7151 | -0.082 | 0.1252 | No |
| 138 | Mms22l | 7293 | -0.094 | 0.1143 | No |
| 139 | Luc7l3 | 7348 | -0.098 | 0.1111 | No |
| 140 | Pold2 | 7468 | -0.106 | 0.1023 | No |
| 141 | Suv39h1 | 7522 | -0.111 | 0.0994 | No |
| 142 | Jpt1 | 7597 | -0.118 | 0.0947 | No |
| 143 | Nbn | 7613 | -0.119 | 0.0953 | No |
| 144 | Mcm2 | 7848 | -0.138 | 0.0769 | No |
| 145 | Chek2 | 7861 | -0.139 | 0.0780 | No |
| 146 | Stag1 | 7871 | -0.140 | 0.0794 | No |
| 147 | Rfc1 | 8100 | -0.157 | 0.0619 | No |
| 148 | Srsf2 | 8105 | -0.157 | 0.0640 | No |
| 149 | Tra2b | 8152 | -0.162 | 0.0625 | No |
| 150 | Usp1 | 8294 | -0.175 | 0.0528 | No |
| 151 | Nup205 | 8350 | -0.178 | 0.0508 | No |
| 152 | Pnn | 8441 | -0.185 | 0.0458 | No |
| 153 | Tubg1 | 8514 | -0.193 | 0.0425 | No |
| 154 | Prps1 | 8529 | -0.195 | 0.0443 | No |
| 155 | Wee1 | 8537 | -0.196 | 0.0467 | No |
| 156 | Gins4 | 8662 | -0.208 | 0.0391 | No |
| 157 | Dck | 8719 | -0.212 | 0.0375 | No |
| 158 | Psmc3ip | 8851 | -0.222 | 0.0295 | No |
| 159 | Timeless | 8869 | -0.224 | 0.0315 | No |
| 160 | Ctcf | 8971 | -0.235 | 0.0262 | No |
| 161 | Rnaseh2a | 8986 | -0.236 | 0.0287 | No |
| 162 | Cdca3 | 9199 | -0.255 | 0.0141 | No |
| 163 | Exosc8 | 9203 | -0.256 | 0.0178 | No |
| 164 | Cse1l | 9221 | -0.257 | 0.0203 | No |
| 165 | Cenpm | 9223 | -0.258 | 0.0242 | No |
| 166 | Ube2s | 9259 | -0.262 | 0.0252 | No |
| 167 | Mcm3 | 9437 | -0.279 | 0.0140 | No |
| 168 | Snrpb | 9448 | -0.279 | 0.0175 | No |
| 169 | Xpo1 | 9655 | -0.300 | 0.0041 | No |
| 170 | Mcm5 | 9695 | -0.304 | 0.0054 | No |
| 171 | Orc2 | 9742 | -0.309 | 0.0062 | No |
| 172 | Rfc2 | 10151 | -0.350 | -0.0241 | No |
| 173 | Nme1 | 10242 | -0.362 | -0.0264 | No |
| 174 | Msh2 | 10244 | -0.363 | -0.0208 | No |
| 175 | Nop56 | 10376 | -0.378 | -0.0264 | No |
| 176 | Tbrg4 | 10421 | -0.383 | -0.0243 | No |
| 177 | Hells | 10431 | -0.384 | -0.0191 | No |
| 178 | Myc | 10470 | -0.388 | -0.0164 | No |
| 179 | Dscc1 | 10511 | -0.395 | -0.0138 | No |
| 180 | Orc6 | 10609 | -0.408 | -0.0159 | No |
| 181 | Trp53 | 10677 | -0.422 | -0.0153 | No |
| 182 | Brms1l | 10686 | -0.423 | -0.0094 | No |
| 183 | Ubr7 | 10698 | -0.426 | -0.0037 | No |
| 184 | Tfrc | 10821 | -0.450 | -0.0074 | No |
| 185 | Mcm6 | 10842 | -0.453 | -0.0021 | No |
| 186 | Pds5b | 10902 | -0.465 | -0.0001 | No |
| 187 | Cdkn3 | 10994 | -0.485 | -0.0005 | No |
| 188 | Gspt1 | 11015 | -0.490 | 0.0054 | No |
| 189 | Nolc1 | 11095 | -0.514 | 0.0064 | No |
| 190 | Gins3 | 11137 | -0.528 | 0.0110 | No |
| 191 | Ccne1 | 11297 | -0.589 | 0.0063 | No |
| 192 | Pa2g4 | 11442 | -0.670 | 0.0041 | No |
| 193 | Ran | 11451 | -0.675 | 0.0138 | No |

