| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group1_versus_Group4.Eosinophil_Pheno.cls #Group1_versus_Group4_repos |
| Phenotype | Eosinophil_Pheno.cls#Group1_versus_Group4_repos |
| Upregulated in class | 0 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | 0.38478038 |
| Normalized Enrichment Score (NES) | 1.3697097 |
| Nominal p-value | 0.16895874 |
| FDR q-value | 0.33893576 |
| FWER p-Value | 0.536 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Brca2 | 12 | 1.300 | 0.0208 | Yes |
| 2 | Rfc3 | 30 | 1.134 | 0.0384 | Yes |
| 3 | Cdc25b | 58 | 1.054 | 0.0538 | Yes |
| 4 | Mad2l1 | 123 | 0.913 | 0.0636 | Yes |
| 5 | Rad21 | 155 | 0.871 | 0.0755 | Yes |
| 6 | Anp32e | 161 | 0.863 | 0.0896 | Yes |
| 7 | Ncapd2 | 182 | 0.839 | 0.1020 | Yes |
| 8 | Plk1 | 186 | 0.837 | 0.1158 | Yes |
| 9 | Cdc25a | 201 | 0.825 | 0.1285 | Yes |
| 10 | Ipo7 | 264 | 0.774 | 0.1361 | Yes |
| 11 | Aurka | 326 | 0.730 | 0.1430 | Yes |
| 12 | Pole | 352 | 0.714 | 0.1529 | Yes |
| 13 | Cdkn2c | 365 | 0.709 | 0.1638 | Yes |
| 14 | Hmgb2 | 371 | 0.707 | 0.1752 | Yes |
| 15 | Psip1 | 384 | 0.701 | 0.1860 | Yes |
| 16 | Plk4 | 411 | 0.692 | 0.1954 | Yes |
| 17 | Ing3 | 425 | 0.688 | 0.2058 | Yes |
| 18 | Ssrp1 | 448 | 0.681 | 0.2153 | Yes |
| 19 | Nasp | 493 | 0.661 | 0.2226 | Yes |
| 20 | Zw10 | 494 | 0.661 | 0.2338 | Yes |
| 21 | Tacc3 | 697 | 0.603 | 0.2262 | Yes |
| 22 | Mlh1 | 770 | 0.582 | 0.2297 | Yes |
| 23 | Dlgap5 | 803 | 0.573 | 0.2366 | Yes |
| 24 | Rad50 | 883 | 0.551 | 0.2389 | Yes |
| 25 | Spc25 | 951 | 0.538 | 0.2421 | Yes |
| 26 | Rad51c | 961 | 0.535 | 0.2503 | Yes |
| 27 | Kif18b | 994 | 0.530 | 0.2565 | Yes |
| 28 | Pola2 | 997 | 0.529 | 0.2652 | Yes |
| 29 | Syncrip | 1041 | 0.519 | 0.2702 | Yes |
| 30 | Mcm4 | 1050 | 0.518 | 0.2782 | Yes |
| 31 | Tmpo | 1084 | 0.509 | 0.2839 | Yes |
| 32 | Lmnb1 | 1180 | 0.493 | 0.2839 | Yes |
| 33 | Mki67 | 1192 | 0.491 | 0.2912 | Yes |
| 34 | Cenpe | 1344 | 0.466 | 0.2858 | Yes |
| 35 | Cbx5 | 1355 | 0.464 | 0.2927 | Yes |
| 36 | Ccp110 | 1387 | 0.459 | 0.2977 | Yes |
| 37 | Rad1 | 1389 | 0.458 | 0.3054 | Yes |
| 38 | Nap1l1 | 1399 | 0.456 | 0.3123 | Yes |
| 39 | Smc4 | 1436 | 0.451 | 0.3167 | Yes |
| 40 | Cdk4 | 1520 | 0.439 | 0.3168 | Yes |
| 41 | Eed | 1724 | 0.406 | 0.3059 | Yes |
| 42 | Pole4 | 1782 | 0.400 | 0.3076 | Yes |
| 43 | Ppm1d | 1837 | 0.394 | 0.3095 | Yes |
| 44 | Pold1 | 1842 | 0.393 | 0.3158 | Yes |
| 45 | Mcm6 | 1857 | 0.390 | 0.3211 | Yes |
| 46 | Melk | 1858 | 0.390 | 0.3277 | Yes |
| 47 | Xrcc6 | 1883 | 0.387 | 0.3321 | Yes |
| 48 | Donson | 1955 | 0.378 | 0.3323 | Yes |
| 49 | Tcf19 | 1980 | 0.374 | 0.3365 | Yes |
| 50 | Cdca8 | 2045 | 0.365 | 0.3370 | Yes |
| 51 | Cdkn1a | 2246 | 0.343 | 0.3253 | Yes |
| 52 | Ranbp1 | 2264 | 0.340 | 0.3295 | Yes |
| 53 | Hmmr | 2272 | 0.339 | 0.3346 | Yes |
| 54 | Hnrnpd | 2374 | 0.329 | 0.3313 | Yes |
| 55 | Cit | 2395 | 0.328 | 0.3351 | Yes |
| 56 | Mcm7 | 2436 | 0.323 | 0.3370 | Yes |
| 57 | Srsf1 | 2490 | 0.318 | 0.3377 | Yes |
| 58 | Cdc20 | 2493 | 0.317 | 0.3429 | Yes |
| 59 | Tubb5 | 2556 | 0.314 | 0.3427 | Yes |
| 60 | Rpa2 | 2569 | 0.313 | 0.3470 | Yes |
| 61 | Rbbp7 | 2661 | 0.302 | 0.3441 | Yes |
| 62 | Chek2 | 2691 | 0.299 | 0.3466 | Yes |
| 63 | H2az1 | 2712 | 0.297 | 0.3498 | Yes |
| 64 | Paics | 2732 | 0.294 | 0.3531 | Yes |
| 65 | Kif2c | 2742 | 0.293 | 0.3572 | Yes |
| 66 | Cnot9 | 2766 | 0.289 | 0.3601 | Yes |
| 67 | Cse1l | 2768 | 0.289 | 0.3649 | Yes |
| 68 | Hus1 | 2837 | 0.283 | 0.3637 | Yes |
| 69 | Lbr | 2852 | 0.282 | 0.3672 | Yes |
| 70 | Ppp1r8 | 2855 | 0.282 | 0.3718 | Yes |
| 71 | Shmt1 | 2898 | 0.276 | 0.3727 | Yes |
| 72 | Kif4 | 2931 | 0.271 | 0.3745 | Yes |
| 73 | Hmgb3 | 3052 | 0.260 | 0.3684 | Yes |
| 74 | Spag5 | 3063 | 0.259 | 0.3718 | Yes |
| 75 | Rad51ap1 | 3077 | 0.257 | 0.3750 | Yes |
| 76 | Brca1 | 3086 | 0.256 | 0.3786 | Yes |
| 77 | Depdc1a | 3101 | 0.254 | 0.3817 | Yes |
| 78 | Tk1 | 3155 | 0.251 | 0.3813 | Yes |
| 79 | Nop56 | 3164 | 0.250 | 0.3848 | Yes |
| 80 | Ilf3 | 3389 | 0.228 | 0.3690 | No |
| 81 | Ak2 | 3498 | 0.219 | 0.3632 | No |
| 82 | Cks1b | 3552 | 0.215 | 0.3622 | No |
| 83 | Nolc1 | 3560 | 0.214 | 0.3652 | No |
| 84 | Mre11a | 3665 | 0.205 | 0.3595 | No |
| 85 | Kif22 | 3709 | 0.200 | 0.3591 | No |
| 86 | Top2a | 3756 | 0.195 | 0.3584 | No |
| 87 | Chek1 | 3809 | 0.188 | 0.3570 | No |
| 88 | Lyar | 3811 | 0.188 | 0.3601 | No |
| 89 | Asf1b | 3831 | 0.186 | 0.3616 | No |
| 90 | Eif2s1 | 3836 | 0.186 | 0.3643 | No |
| 91 | Ung | 3855 | 0.185 | 0.3659 | No |
| 92 | Aurkb | 3903 | 0.180 | 0.3648 | No |
| 93 | Diaph3 | 4014 | 0.168 | 0.3580 | No |
| 94 | Pttg1 | 4114 | 0.160 | 0.3520 | No |
| 95 | Nme1 | 4122 | 0.160 | 0.3541 | No |
| 96 | Slbp | 4154 | 0.157 | 0.3540 | No |
| 97 | Cdk1 | 4157 | 0.157 | 0.3565 | No |
| 98 | Dek | 4160 | 0.157 | 0.3590 | No |
| 99 | Dclre1b | 4236 | 0.149 | 0.3549 | No |
| 100 | Asf1a | 4299 | 0.142 | 0.3519 | No |
| 101 | Ran | 4317 | 0.140 | 0.3527 | No |
| 102 | Prps1 | 4320 | 0.139 | 0.3549 | No |
| 103 | Gins3 | 4473 | 0.135 | 0.3439 | No |
| 104 | Ezh2 | 4507 | 0.132 | 0.3432 | No |
| 105 | Lig1 | 4589 | 0.124 | 0.3382 | No |
| 106 | Spc24 | 4615 | 0.122 | 0.3381 | No |
| 107 | Rfc2 | 4693 | 0.115 | 0.3332 | No |
| 108 | Trp53 | 4793 | 0.108 | 0.3264 | No |
| 109 | Ctcf | 4837 | 0.104 | 0.3244 | No |
| 110 | Tra2b | 4872 | 0.100 | 0.3231 | No |
| 111 | Cks2 | 4875 | 0.100 | 0.3246 | No |
| 112 | Pold3 | 4960 | 0.093 | 0.3188 | No |
| 113 | Dctpp1 | 5008 | 0.089 | 0.3162 | No |
| 114 | Nup153 | 5039 | 0.086 | 0.3150 | No |
| 115 | Mcm5 | 5042 | 0.086 | 0.3163 | No |
| 116 | Bard1 | 5066 | 0.083 | 0.3157 | No |
| 117 | Dut | 5136 | 0.078 | 0.3109 | No |
| 118 | Tbrg4 | 5355 | 0.058 | 0.2928 | No |
| 119 | Smc1a | 5361 | 0.058 | 0.2934 | No |
| 120 | Dnmt1 | 5417 | 0.054 | 0.2895 | No |
| 121 | Gins1 | 5493 | 0.047 | 0.2837 | No |
| 122 | Usp1 | 5496 | 0.047 | 0.2843 | No |
| 123 | Atad2 | 5674 | 0.033 | 0.2694 | No |
| 124 | Stag1 | 5679 | 0.033 | 0.2696 | No |
| 125 | Smc3 | 5750 | 0.028 | 0.2639 | No |
| 126 | Prim2 | 5751 | 0.028 | 0.2644 | No |
| 127 | Nudt21 | 5775 | 0.026 | 0.2628 | No |
| 128 | Espl1 | 5802 | 0.024 | 0.2609 | No |
| 129 | Nup107 | 5824 | 0.022 | 0.2595 | No |
| 130 | Tipin | 5831 | 0.021 | 0.2593 | No |
| 131 | Xpo1 | 5856 | 0.019 | 0.2575 | No |
| 132 | Ube2t | 5975 | 0.008 | 0.2473 | No |
| 133 | Suv39h1 | 6020 | 0.005 | 0.2436 | No |
| 134 | Racgap1 | 6229 | -0.004 | 0.2254 | No |
| 135 | Srsf2 | 6329 | -0.012 | 0.2169 | No |
| 136 | Pcna | 6374 | -0.016 | 0.2133 | No |
| 137 | Luc7l3 | 6633 | -0.031 | 0.1913 | No |
| 138 | Wdr90 | 6647 | -0.032 | 0.1907 | No |
| 139 | Bub1b | 6649 | -0.032 | 0.1911 | No |
| 140 | Orc2 | 6651 | -0.032 | 0.1916 | No |
| 141 | Mybl2 | 6862 | -0.051 | 0.1740 | No |
| 142 | Gspt1 | 6974 | -0.059 | 0.1653 | No |
| 143 | Cenpm | 7006 | -0.061 | 0.1636 | No |
| 144 | Rpa1 | 7047 | -0.065 | 0.1612 | No |
| 145 | Pnn | 7123 | -0.070 | 0.1558 | No |
| 146 | Mthfd2 | 7303 | -0.083 | 0.1415 | No |
| 147 | Mcm2 | 7305 | -0.084 | 0.1429 | No |
| 148 | Cdkn1b | 7432 | -0.095 | 0.1334 | No |
| 149 | E2f8 | 7712 | -0.117 | 0.1110 | No |
| 150 | Ddx39a | 7741 | -0.120 | 0.1105 | No |
| 151 | Trip13 | 7965 | -0.138 | 0.0933 | No |
| 152 | Pms2 | 7967 | -0.139 | 0.0956 | No |
| 153 | Pds5b | 8013 | -0.142 | 0.0940 | No |
| 154 | H2ax | 8104 | -0.149 | 0.0886 | No |
| 155 | Rfc1 | 8235 | -0.155 | 0.0798 | No |
| 156 | Rrm2 | 8332 | -0.161 | 0.0742 | No |
| 157 | Birc5 | 8409 | -0.168 | 0.0703 | No |
| 158 | Hells | 8571 | -0.184 | 0.0593 | No |
| 159 | Ubr7 | 8652 | -0.192 | 0.0555 | No |
| 160 | Prkdc | 8796 | -0.205 | 0.0465 | No |
| 161 | Dscc1 | 8812 | -0.207 | 0.0486 | No |
| 162 | Jpt1 | 8824 | -0.208 | 0.0512 | No |
| 163 | Tfrc | 8846 | -0.210 | 0.0529 | No |
| 164 | Ccnb2 | 8921 | -0.217 | 0.0501 | No |
| 165 | Smc6 | 8945 | -0.219 | 0.0517 | No |
| 166 | Nbn | 9067 | -0.227 | 0.0449 | No |
| 167 | Mms22l | 9131 | -0.232 | 0.0433 | No |
| 168 | Rpa3 | 9337 | -0.253 | 0.0296 | No |
| 169 | Pold2 | 9400 | -0.260 | 0.0286 | No |
| 170 | Snrpb | 9482 | -0.268 | 0.0260 | No |
| 171 | Nup205 | 9549 | -0.274 | 0.0249 | No |
| 172 | Stmn1 | 9551 | -0.274 | 0.0294 | No |
| 173 | Timeless | 9555 | -0.274 | 0.0337 | No |
| 174 | Orc6 | 9748 | -0.296 | 0.0219 | No |
| 175 | Pa2g4 | 9931 | -0.315 | 0.0113 | No |
| 176 | Pan2 | 9935 | -0.316 | 0.0163 | No |
| 177 | Lsm8 | 10228 | -0.350 | -0.0034 | No |
| 178 | Phf5a | 10422 | -0.377 | -0.0139 | No |
| 179 | Dck | 10434 | -0.379 | -0.0085 | No |
| 180 | Msh2 | 10480 | -0.381 | -0.0060 | No |
| 181 | Wee1 | 10517 | -0.385 | -0.0027 | No |
| 182 | Ccne1 | 10542 | -0.388 | 0.0017 | No |
| 183 | Myc | 10608 | -0.401 | 0.0028 | No |
| 184 | Rnaseh2a | 10647 | -0.408 | 0.0064 | No |
| 185 | Cdca3 | 10786 | -0.430 | 0.0015 | No |
| 186 | Gins4 | 10801 | -0.434 | 0.0076 | No |
| 187 | Brms1l | 10852 | -0.447 | 0.0107 | No |
| 188 | Exosc8 | 10945 | -0.469 | 0.0106 | No |
| 189 | Psmc3ip | 10980 | -0.477 | 0.0156 | No |
| 190 | Mcm3 | 10988 | -0.479 | 0.0231 | No |
| 191 | Tubg1 | 11345 | -0.597 | 0.0019 | No |
| 192 | Cdkn3 | 11390 | -0.617 | 0.0085 | No |
| 193 | Ube2s | 11415 | -0.631 | 0.0170 | No |

