Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group1_versus_Group3.Eosinophil_Pheno.cls #Group1_versus_Group3_repos |
| Phenotype | Eosinophil_Pheno.cls#Group1_versus_Group3_repos |
| Upregulated in class | 2 |
| GeneSet | HALLMARK_IL6_JAK_STAT3_SIGNALING |
| Enrichment Score (ES) | -0.4353915 |
| Normalized Enrichment Score (NES) | -1.5870912 |
| Nominal p-value | 0.007905139 |
| FDR q-value | 0.3136615 |
| FWER p-Value | 0.177 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Grb2 | 250 | 0.602 | 0.0154 | No |
| 2 | Hax1 | 420 | 0.525 | 0.0330 | No |
| 3 | Cd44 | 809 | 0.429 | 0.0258 | No |
| 4 | Myd88 | 1001 | 0.393 | 0.0334 | No |
| 5 | Socs1 | 1120 | 0.373 | 0.0461 | No |
| 6 | Ptpn1 | 1218 | 0.359 | 0.0597 | No |
| 7 | Il15ra | 1660 | 0.296 | 0.0398 | No |
| 8 | Itga4 | 1813 | 0.278 | 0.0437 | No |
| 9 | Ptpn11 | 2067 | 0.255 | 0.0375 | No |
| 10 | Ltbr | 2463 | 0.220 | 0.0168 | No |
| 11 | Stam2 | 3137 | 0.160 | -0.0316 | No |
| 12 | Stat3 | 4165 | 0.078 | -0.1156 | No |
| 13 | Il10rb | 4319 | 0.065 | -0.1248 | No |
| 14 | Stat2 | 4346 | 0.064 | -0.1232 | No |
| 15 | Tgfb1 | 4486 | 0.054 | -0.1319 | No |
| 16 | Jun | 4608 | 0.045 | -0.1396 | No |
| 17 | Tnfrsf1b | 4938 | 0.021 | -0.1667 | No |
| 18 | Acvr1b | 5222 | 0.001 | -0.1912 | No |
| 19 | Irf9 | 5262 | -0.001 | -0.1944 | No |
| 20 | Bak1 | 5306 | -0.005 | -0.1979 | No |
| 21 | Ifngr1 | 5624 | -0.028 | -0.2236 | No |
| 22 | Tnfrsf21 | 5927 | -0.049 | -0.2467 | No |
| 23 | Cbl | 6595 | -0.098 | -0.2984 | No |
| 24 | Il3ra | 6917 | -0.122 | -0.3186 | No |
| 25 | Ifnar1 | 7240 | -0.147 | -0.3374 | No |
| 26 | Irf1 | 7246 | -0.148 | -0.3288 | No |
| 27 | Map3k8 | 7442 | -0.161 | -0.3357 | No |
| 28 | Il4ra | 7594 | -0.175 | -0.3380 | No |
| 29 | Il1r1 | 8315 | -0.235 | -0.3859 | No |
| 30 | Ebi3 | 8581 | -0.259 | -0.3929 | No |
| 31 | Stat1 | 9073 | -0.305 | -0.4166 | Yes |
| 32 | Csf1 | 9197 | -0.320 | -0.4076 | Yes |
| 33 | Csf2ra | 9293 | -0.331 | -0.3955 | Yes |
| 34 | Ptpn2 | 9296 | -0.331 | -0.3754 | Yes |
| 35 | Cd9 | 9637 | -0.369 | -0.3821 | Yes |
| 36 | Pim1 | 9763 | -0.382 | -0.3695 | Yes |
| 37 | Crlf2 | 9957 | -0.411 | -0.3609 | Yes |
| 38 | Il17rb | 9960 | -0.412 | -0.3358 | Yes |
| 39 | Itgb3 | 10084 | -0.430 | -0.3200 | Yes |
| 40 | Il18r1 | 10550 | -0.504 | -0.3293 | Yes |
| 41 | Il17ra | 10671 | -0.529 | -0.3072 | Yes |
| 42 | Pik3r5 | 10823 | -0.562 | -0.2857 | Yes |
| 43 | Tnfrsf1a | 10967 | -0.594 | -0.2617 | Yes |
| 44 | Il6st | 11110 | -0.641 | -0.2346 | Yes |
| 45 | Fas | 11427 | -0.812 | -0.2120 | Yes |
| 46 | Tyk2 | 11439 | -0.827 | -0.1622 | Yes |
| 47 | Csf3r | 11457 | -0.853 | -0.1113 | Yes |
| 48 | Il2rg | 11551 | -1.012 | -0.0572 | Yes |
| 49 | Ifngr2 | 11552 | -1.012 | 0.0049 | Yes |
