| Dataset | Eosinophil.Eosinophil_Pheno.cls #Group1_versus_Group2.Eosinophil_Pheno.cls #Group1_versus_Group2_repos |
| Phenotype | Eosinophil_Pheno.cls#Group1_versus_Group2_repos |
| Upregulated in class | 1 |
| GeneSet | HALLMARK_E2F_TARGETS |
| Enrichment Score (ES) | -0.22274455 |
| Normalized Enrichment Score (NES) | -0.9832727 |
| Nominal p-value | 0.47188756 |
| FDR q-value | 0.59744585 |
| FWER p-Value | 1.0 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Tbrg4 | 14 | 1.153 | 0.0172 | No |
| 2 | Trp53 | 19 | 1.120 | 0.0348 | No |
| 3 | Rfc2 | 28 | 1.075 | 0.0513 | No |
| 4 | Nolc1 | 79 | 0.895 | 0.0612 | No |
| 5 | Ran | 126 | 0.823 | 0.0703 | No |
| 6 | Mlh1 | 148 | 0.790 | 0.0811 | No |
| 7 | Gspt1 | 156 | 0.780 | 0.0930 | No |
| 8 | Gins3 | 178 | 0.760 | 0.1033 | No |
| 9 | Mcm6 | 220 | 0.726 | 0.1113 | No |
| 10 | Nop56 | 319 | 0.662 | 0.1133 | No |
| 11 | Rad50 | 326 | 0.657 | 0.1233 | No |
| 12 | Ranbp1 | 381 | 0.635 | 0.1287 | No |
| 13 | Hnrnpd | 435 | 0.612 | 0.1339 | No |
| 14 | Ipo7 | 444 | 0.609 | 0.1429 | No |
| 15 | Cdc25a | 466 | 0.602 | 0.1507 | No |
| 16 | Cse1l | 507 | 0.585 | 0.1566 | No |
| 17 | Cdk4 | 564 | 0.571 | 0.1608 | No |
| 18 | Mcm5 | 569 | 0.568 | 0.1695 | No |
| 19 | Chek2 | 616 | 0.551 | 0.1743 | No |
| 20 | Pole4 | 640 | 0.546 | 0.1810 | No |
| 21 | Nme1 | 791 | 0.508 | 0.1760 | No |
| 22 | Ing3 | 824 | 0.502 | 0.1812 | No |
| 23 | Ctcf | 908 | 0.480 | 0.1816 | No |
| 24 | Rfc3 | 978 | 0.467 | 0.1831 | No |
| 25 | Ssrp1 | 1124 | 0.442 | 0.1774 | No |
| 26 | Prps1 | 1249 | 0.420 | 0.1733 | No |
| 27 | Xpo1 | 1399 | 0.399 | 0.1666 | No |
| 28 | Ccne1 | 1404 | 0.398 | 0.1726 | No |
| 29 | Pa2g4 | 1408 | 0.397 | 0.1787 | No |
| 30 | Nap1l1 | 1455 | 0.390 | 0.1809 | No |
| 31 | Brca2 | 1481 | 0.385 | 0.1849 | No |
| 32 | Tra2b | 1565 | 0.374 | 0.1836 | No |
| 33 | Cenpm | 1652 | 0.362 | 0.1819 | No |
| 34 | Rpa2 | 1663 | 0.361 | 0.1867 | No |
| 35 | Cnot9 | 1763 | 0.351 | 0.1837 | No |
| 36 | Hus1 | 1789 | 0.347 | 0.1870 | No |
| 37 | Cdkn1a | 1826 | 0.343 | 0.1894 | No |
| 38 | Rad1 | 1879 | 0.338 | 0.1902 | No |
| 39 | Pds5b | 2035 | 0.320 | 0.1818 | No |
| 40 | Pola2 | 2059 | 0.318 | 0.1848 | No |
| 41 | Orc2 | 2192 | 0.303 | 0.1781 | No |
| 42 | Eif2s1 | 2243 | 0.299 | 0.1785 | No |
| 43 | Ppm1d | 2259 | 0.297 | 0.1820 | No |
| 44 | Tfrc | 2360 | 0.284 | 0.1777 | No |
| 45 | Usp1 | 2363 | 0.284 | 0.1821 | No |
| 46 | Cbx5 | 2390 | 0.281 | 0.1843 | No |
| 47 | Chek1 | 2475 | 0.273 | 0.1813 | No |
| 48 | Srsf2 | 2831 | 0.241 | 0.1541 | No |
| 49 | Hells | 2923 | 0.232 | 0.1498 | No |
| 50 | Mre11a | 2946 | 0.230 | 0.1516 | No |
| 51 | Ubr7 | 3043 | 0.221 | 0.1467 | No |
| 52 | Ppp1r8 | 3165 | 0.212 | 0.1395 | No |
| 53 | Ung | 3193 | 0.210 | 0.1405 | No |
| 54 | Mcm7 | 3247 | 0.206 | 0.1391 | No |
| 55 | Lyar | 3285 | 0.202 | 0.1391 | No |
| 56 | Plk1 | 3301 | 0.200 | 0.1410 | No |
| 57 | Psip1 | 3307 | 0.200 | 0.1438 | No |
| 58 | Dscc1 | 3356 | 0.195 | 0.1427 | No |
| 59 | Asf1b | 3360 | 0.195 | 0.1455 | No |
| 60 | Paics | 3440 | 0.189 | 0.1416 | No |
| 61 | Smc1a | 3450 | 0.188 | 0.1439 | No |
| 62 | Nup153 | 3479 | 0.186 | 0.1444 | No |
| 63 | Tcf19 | 3527 | 0.182 | 0.1432 | No |
| 64 | Stag1 | 3559 | 0.178 | 0.1433 | No |
| 65 | Pnn | 3570 | 0.177 | 0.1453 | No |
| 66 | Gins1 | 3612 | 0.176 | 0.1445 | No |
| 67 | Rad51c | 3625 | 0.174 | 0.1462 | No |
| 68 | H2az1 | 3638 | 0.173 | 0.1479 | No |
| 69 | Dek | 3689 | 0.168 | 0.1462 | No |
| 70 | Hmgb3 | 3716 | 0.167 | 0.1466 | No |
| 71 | Nudt21 | 3721 | 0.166 | 0.1489 | No |
| 72 | Orc6 | 3810 | 0.157 | 0.1437 | No |
| 73 | Cks1b | 3836 | 0.155 | 0.1440 | No |
| 74 | Tk1 | 3842 | 0.155 | 0.1461 | No |
| 75 | Melk | 3845 | 0.154 | 0.1484 | No |
| 76 | Nasp | 3857 | 0.153 | 0.1498 | No |
| 77 | Srsf1 | 3978 | 0.143 | 0.1416 | No |
| 78 | Myc | 3984 | 0.143 | 0.1435 | No |
| 79 | Suv39h1 | 4012 | 0.140 | 0.1433 | No |
| 80 | Lbr | 4049 | 0.138 | 0.1424 | No |
| 81 | Asf1a | 4118 | 0.134 | 0.1386 | No |
| 82 | Shmt1 | 4474 | 0.107 | 0.1092 | No |
| 83 | Syncrip | 4525 | 0.103 | 0.1065 | No |
| 84 | Ilf3 | 4543 | 0.102 | 0.1066 | No |
| 85 | Luc7l3 | 4573 | 0.100 | 0.1057 | No |
| 86 | Anp32e | 4645 | 0.095 | 0.1010 | No |
| 87 | Mcm2 | 4810 | 0.081 | 0.0879 | No |
| 88 | Dnmt1 | 5044 | 0.063 | 0.0685 | No |
| 89 | Donson | 5134 | 0.056 | 0.0616 | No |
| 90 | Pole | 5169 | 0.053 | 0.0595 | No |
| 91 | Rfc1 | 5234 | 0.048 | 0.0546 | No |
| 92 | Xrcc6 | 5439 | 0.032 | 0.0373 | No |
| 93 | Snrpb | 5667 | 0.016 | 0.0176 | No |
| 94 | Cdc25b | 5689 | 0.014 | 0.0160 | No |
| 95 | Pttg1 | 5743 | 0.010 | 0.0116 | No |
| 96 | Rad51ap1 | 5863 | 0.001 | 0.0012 | No |
| 97 | Ezh2 | 5877 | 0.000 | 0.0000 | No |
| 98 | Lmnb1 | 6210 | -0.023 | -0.0287 | No |
| 99 | Msh2 | 6278 | -0.028 | -0.0341 | No |
| 100 | Cdc20 | 6354 | -0.033 | -0.0401 | No |
| 101 | Tubb5 | 6401 | -0.037 | -0.0436 | No |
| 102 | Slbp | 6418 | -0.038 | -0.0444 | No |
| 103 | Atad2 | 6472 | -0.042 | -0.0484 | No |
| 104 | Dut | 6513 | -0.046 | -0.0511 | No |
| 105 | Ddx39a | 6529 | -0.047 | -0.0517 | No |
| 106 | Wdr90 | 6555 | -0.050 | -0.0531 | No |
| 107 | Tmpo | 6578 | -0.051 | -0.0542 | No |
| 108 | Smc3 | 6612 | -0.054 | -0.0562 | No |
| 109 | Timeless | 6624 | -0.055 | -0.0563 | No |
| 110 | Aurka | 6675 | -0.059 | -0.0597 | No |
| 111 | Rpa1 | 6706 | -0.062 | -0.0614 | No |
| 112 | Zw10 | 6783 | -0.068 | -0.0669 | No |
| 113 | Bard1 | 7050 | -0.091 | -0.0888 | No |
| 114 | Tipin | 7157 | -0.098 | -0.0965 | No |
| 115 | Dclre1b | 7283 | -0.107 | -0.1057 | No |
| 116 | Pold1 | 7337 | -0.111 | -0.1086 | No |
| 117 | Hmgb2 | 7386 | -0.115 | -0.1110 | No |
| 118 | Pcna | 7455 | -0.119 | -0.1150 | No |
| 119 | Mybl2 | 7540 | -0.125 | -0.1204 | No |
| 120 | Nup205 | 7634 | -0.132 | -0.1264 | No |
| 121 | Jpt1 | 7641 | -0.133 | -0.1248 | No |
| 122 | Pold3 | 7699 | -0.137 | -0.1276 | No |
| 123 | Mcm3 | 7713 | -0.138 | -0.1265 | No |
| 124 | Ube2t | 7735 | -0.140 | -0.1261 | No |
| 125 | Trip13 | 7767 | -0.142 | -0.1266 | No |
| 126 | Brms1l | 7842 | -0.148 | -0.1307 | No |
| 127 | Ak2 | 7883 | -0.151 | -0.1318 | No |
| 128 | Nup107 | 7946 | -0.157 | -0.1347 | No |
| 129 | Rbbp7 | 7965 | -0.159 | -0.1338 | No |
| 130 | Rad21 | 7987 | -0.160 | -0.1330 | No |
| 131 | H2ax | 7988 | -0.160 | -0.1305 | No |
| 132 | Lig1 | 8010 | -0.162 | -0.1297 | No |
| 133 | Pold2 | 8122 | -0.171 | -0.1367 | No |
| 134 | Nbn | 8129 | -0.172 | -0.1345 | No |
| 135 | Smc6 | 8162 | -0.174 | -0.1345 | No |
| 136 | Mms22l | 8261 | -0.184 | -0.1402 | No |
| 137 | Mthfd2 | 8352 | -0.192 | -0.1450 | No |
| 138 | Kif18b | 8368 | -0.193 | -0.1432 | No |
| 139 | Gins4 | 8796 | -0.232 | -0.1769 | No |
| 140 | Dctpp1 | 8817 | -0.233 | -0.1749 | No |
| 141 | Tacc3 | 8870 | -0.239 | -0.1756 | No |
| 142 | Bub1b | 8969 | -0.248 | -0.1803 | No |
| 143 | Spag5 | 9055 | -0.255 | -0.1836 | No |
| 144 | Cdkn2c | 9087 | -0.260 | -0.1822 | No |
| 145 | Cdca3 | 9149 | -0.267 | -0.1833 | No |
| 146 | Mad2l1 | 9244 | -0.276 | -0.1871 | No |
| 147 | Smc4 | 9277 | -0.280 | -0.1854 | No |
| 148 | Rpa3 | 9391 | -0.289 | -0.1907 | No |
| 149 | Brca1 | 9504 | -0.301 | -0.1957 | No |
| 150 | Kif22 | 9554 | -0.306 | -0.1951 | No |
| 151 | Plk4 | 9721 | -0.324 | -0.2044 | No |
| 152 | Pan2 | 9931 | -0.350 | -0.2171 | Yes |
| 153 | Mcm4 | 9979 | -0.356 | -0.2156 | Yes |
| 154 | Rrm2 | 10017 | -0.361 | -0.2130 | Yes |
| 155 | Espl1 | 10019 | -0.361 | -0.2074 | Yes |
| 156 | Phf5a | 10136 | -0.374 | -0.2115 | Yes |
| 157 | Cdkn3 | 10137 | -0.374 | -0.2055 | Yes |
| 158 | Cdca8 | 10143 | -0.375 | -0.2000 | Yes |
| 159 | Aurkb | 10175 | -0.381 | -0.1966 | Yes |
| 160 | Wee1 | 10204 | -0.385 | -0.1929 | Yes |
| 161 | Dck | 10218 | -0.387 | -0.1878 | Yes |
| 162 | Stmn1 | 10330 | -0.401 | -0.1911 | Yes |
| 163 | Ccp110 | 10433 | -0.415 | -0.1935 | Yes |
| 164 | Rnaseh2a | 10515 | -0.430 | -0.1937 | Yes |
| 165 | Ncapd2 | 10585 | -0.443 | -0.1926 | Yes |
| 166 | Psmc3ip | 10604 | -0.445 | -0.1871 | Yes |
| 167 | Pms2 | 10621 | -0.447 | -0.1813 | Yes |
| 168 | Cenpe | 10648 | -0.453 | -0.1764 | Yes |
| 169 | Mki67 | 10653 | -0.453 | -0.1695 | Yes |
| 170 | Exosc8 | 10717 | -0.464 | -0.1676 | Yes |
| 171 | Top2a | 10744 | -0.468 | -0.1624 | Yes |
| 172 | Prkdc | 10882 | -0.500 | -0.1664 | Yes |
| 173 | Hmmr | 10884 | -0.501 | -0.1585 | Yes |
| 174 | Spc24 | 10898 | -0.503 | -0.1516 | Yes |
| 175 | Diaph3 | 10916 | -0.508 | -0.1449 | Yes |
| 176 | Ccnb2 | 10924 | -0.510 | -0.1374 | Yes |
| 177 | Prim2 | 11171 | -0.583 | -0.1496 | Yes |
| 178 | Cdkn1b | 11177 | -0.584 | -0.1407 | Yes |
| 179 | Eed | 11189 | -0.591 | -0.1322 | Yes |
| 180 | Racgap1 | 11209 | -0.600 | -0.1243 | Yes |
| 181 | Tubg1 | 11301 | -0.632 | -0.1222 | Yes |
| 182 | Spc25 | 11318 | -0.644 | -0.1133 | Yes |
| 183 | Cks2 | 11331 | -0.653 | -0.1039 | Yes |
| 184 | Birc5 | 11386 | -0.682 | -0.0977 | Yes |
| 185 | Cdk1 | 11424 | -0.712 | -0.0895 | Yes |
| 186 | Depdc1a | 11428 | -0.716 | -0.0784 | Yes |
| 187 | E2f8 | 11482 | -0.770 | -0.0707 | Yes |
| 188 | Cit | 11488 | -0.783 | -0.0586 | Yes |
| 189 | Lsm8 | 11490 | -0.784 | -0.0462 | Yes |
| 190 | Dlgap5 | 11535 | -0.853 | -0.0364 | Yes |
| 191 | Ube2s | 11543 | -0.871 | -0.0231 | Yes |
| 192 | Kif2c | 11545 | -0.877 | -0.0091 | Yes |
| 193 | Kif4 | 11556 | -0.916 | 0.0046 | Yes |

