Details for gene set HALLMARK_PI3K_AKT_MTOR

Table: GSEA Results Summary

Dataset	CMP.CMP_Pheno.cls#Group6_versus_Group8.CMP_Pheno.cls#Group6_versus_Group8_repos
Phenotype	CMP_Pheno.cls#Group6_versus_Group8_repos
Upregulated in class	5
GeneSet	HALLMARK_PI3K_AKT_MTOR_SIGNALING
Enrichment Score (ES)	-0.25273842
Normalized Enrichment Score (NES)	-1.1996304
Nominal p-value	0.21343873
FDR q-value	0.29759857
FWER p-Value	0.905

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	Tsc2	643	0.545	-0.0001	No
2	Map3k7	1779	0.384	-0.0349	No
3	Nod1	2160	0.337	-0.0341	No
4	Mapk9	2555	0.300	-0.0362	No
5	Trib3	2679	0.293	-0.0250	No
6	Ube2n	2804	0.283	-0.0144	No
7	Ptpn11	3012	0.269	-0.0089	No
8	Smad2	3156	0.263	-0.0004	No
9	Mapk8	4138	0.224	-0.0369	No
10	Sqstm1	4298	0.215	-0.0322	No
11	Adcy2	4413	0.207	-0.0256	No
12	Plcg1	4451	0.205	-0.0152	No
13	Gna14	4670	0.194	-0.0147	No
14	Camk4	4872	0.184	-0.0139	No
15	Ralb	4875	0.184	-0.0030	No
16	Tbk1	5106	0.173	-0.0044	No
17	Prkag1	5210	0.167	0.0004	No
18	Egfr	5238	0.166	0.0089	No
19	Cdk1	5269	0.165	0.0172	No
20	Cdkn1b	5894	0.138	-0.0063	No
21	Ppp2r1b	6242	0.123	-0.0165	No
22	Vav3	6309	0.121	-0.0127	No
23	Ripk1	6397	0.117	-0.0101	No
24	Tiam1	6555	0.112	-0.0114	No
25	Gsk3b	6938	0.098	-0.0250	No
26	Plcb1	7117	0.092	-0.0285	No
27	Acaca	7236	0.086	-0.0294	No
28	Grb2	7375	0.082	-0.0315	No
29	Itpr2	7609	0.074	-0.0390	No
30	Rptor	7636	0.073	-0.0359	No
31	Pfn1	7710	0.071	-0.0354	No
32	Pten	7906	0.065	-0.0415	No
33	Grk2	8267	0.053	-0.0566	No
34	Pla2g12a	8614	0.043	-0.0716	No
35	Ap2m1	8622	0.043	-0.0694	No
36	Cltc	8870	0.034	-0.0800	No
37	Actr3	9157	0.025	-0.0930	No
38	Arhgdia	9343	0.018	-0.1014	No
39	Prkar2a	9552	0.012	-0.1113	No
40	Map2k3	9766	0.004	-0.1218	No
41	Cdkn1a	9815	0.003	-0.1241	No
42	Hsp90b1	10229	-0.001	-0.1451	No
43	Raf1	10587	-0.012	-0.1625	No
44	Eif4e	10730	-0.016	-0.1687	No
45	Cxcr4	11117	-0.029	-0.1866	No
46	Il2rg	11322	-0.036	-0.1948	No
47	E2f1	11415	-0.039	-0.1972	No
48	Pitx2	11730	-0.048	-0.2103	No
49	Cdk4	11737	-0.048	-0.2077	No
50	Map2k6	11819	-0.051	-0.2088	No
51	Mapk10	11972	-0.058	-0.2131	No
52	Pak4	11987	-0.058	-0.2103	No
53	Nck1	12250	-0.068	-0.2196	No
54	Traf2	12341	-0.071	-0.2199	No
55	Dapp1	12342	-0.071	-0.2157	No
56	Pin1	12401	-0.073	-0.2143	No
57	Mknk2	12798	-0.087	-0.2292	No
58	Irak4	13133	-0.100	-0.2402	No
59	Cab39	13139	-0.101	-0.2345	No
60	Mapk1	13399	-0.111	-0.2410	No
61	Mapkap1	13612	-0.119	-0.2446	Yes
62	Actr2	13642	-0.120	-0.2389	Yes
63	Prkcb	13732	-0.125	-0.2360	Yes
64	Rps6ka1	14062	-0.139	-0.2445	Yes
65	Rac1	14110	-0.141	-0.2385	Yes
66	Ecsit	14225	-0.145	-0.2356	Yes
67	Prkaa2	14259	-0.147	-0.2285	Yes
68	Rps6ka3	14266	-0.147	-0.2200	Yes
69	Pikfyve	14390	-0.153	-0.2171	Yes
70	Stat2	14392	-0.153	-0.2081	Yes
71	Mknk1	14408	-0.153	-0.1997	Yes
72	Them4	14563	-0.160	-0.1980	Yes
73	Arf1	14568	-0.160	-0.1886	Yes
74	Ywhab	15033	-0.183	-0.2013	Yes
75	Pdk1	15041	-0.183	-0.1908	Yes
76	Rit1	15043	-0.183	-0.1799	Yes
77	Sla	15140	-0.187	-0.1736	Yes
78	Cab39l	15230	-0.190	-0.1668	Yes
79	Sfn	15241	-0.191	-0.1559	Yes
80	Pik3r3	15511	-0.204	-0.1574	Yes
81	Akt1s1	15641	-0.210	-0.1514	Yes
82	Calr	15865	-0.221	-0.1496	Yes
83	Nfkbib	15905	-0.222	-0.1383	Yes
84	Akt1	16046	-0.231	-0.1316	Yes
85	Myd88	16436	-0.249	-0.1365	Yes
86	Atf1	16466	-0.251	-0.1230	Yes
87	Tnfrsf1a	16491	-0.252	-0.1092	Yes
88	Cdk2	16494	-0.252	-0.0943	Yes
89	Hras	16548	-0.255	-0.0817	Yes
90	Dusp3	16875	-0.275	-0.0818	Yes
91	Ube2d3	17047	-0.284	-0.0736	Yes
92	Slc2a1	17239	-0.295	-0.0657	Yes
93	Csnk2b	17608	-0.324	-0.0650	Yes
94	Lck	17804	-0.336	-0.0549	Yes
95	Arpc3	17887	-0.343	-0.0385	Yes
96	Ddit3	19101	-0.502	-0.0702	Yes
97	Cfl1	19290	-0.544	-0.0473	Yes
98	Ppp1ca	19304	-0.547	-0.0153	Yes
99	Il4	19561	-0.653	0.0107	Yes