| Dataset | CMP.CMP_Pheno.cls#Group6_versus_Group8.CMP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | CMP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 5 |
| GeneSet | HALLMARK_MTORC1_SIGNALING |
| Enrichment Score (ES) | -0.28356105 |
| Normalized Enrichment Score (NES) | -1.2048308 |
| Nominal p-value | 0.2421875 |
| FDR q-value | 0.30692244 |
| FWER p-Value | 0.902 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Bcat1 | 655 | 0.543 | -0.0180 | No |
| 2 | Slc7a11 | 679 | 0.535 | -0.0040 | No |
| 3 | Abcf2 | 774 | 0.506 | 0.0056 | No |
| 4 | Aurka | 826 | 0.495 | 0.0171 | No |
| 5 | Sqle | 1593 | 0.404 | -0.0106 | No |
| 6 | Serpinh1 | 1645 | 0.400 | -0.0018 | No |
| 7 | Slc7a5 | 1673 | 0.399 | 0.0081 | No |
| 8 | Cth | 1788 | 0.383 | 0.0132 | No |
| 9 | Slc37a4 | 1898 | 0.369 | 0.0181 | No |
| 10 | Idi1 | 1955 | 0.360 | 0.0255 | No |
| 11 | Dhfr | 2262 | 0.327 | 0.0191 | No |
| 12 | Mthfd2l | 2308 | 0.323 | 0.0260 | No |
| 13 | Cfp | 2363 | 0.317 | 0.0323 | No |
| 14 | Tm7sf2 | 2417 | 0.312 | 0.0385 | No |
| 15 | Trib3 | 2679 | 0.293 | 0.0334 | No |
| 16 | Ppp1r15a | 2882 | 0.278 | 0.0310 | No |
| 17 | Vldlr | 3093 | 0.267 | 0.0279 | No |
| 18 | Nup205 | 3168 | 0.262 | 0.0316 | No |
| 19 | Gclc | 3318 | 0.256 | 0.0312 | No |
| 20 | Add3 | 3537 | 0.250 | 0.0272 | No |
| 21 | Ifrd1 | 3580 | 0.248 | 0.0321 | No |
| 22 | Nupr1 | 3785 | 0.235 | 0.0284 | No |
| 23 | Bub1 | 3964 | 0.228 | 0.0258 | No |
| 24 | Sqstm1 | 4298 | 0.215 | 0.0149 | No |
| 25 | Cyb5b | 4383 | 0.209 | 0.0166 | No |
| 26 | Phgdh | 4592 | 0.197 | 0.0115 | No |
| 27 | Psmd14 | 4673 | 0.194 | 0.0130 | No |
| 28 | Psma4 | 4697 | 0.193 | 0.0173 | No |
| 29 | Sc5d | 4957 | 0.181 | 0.0092 | No |
| 30 | Slc2a3 | 4967 | 0.180 | 0.0138 | No |
| 31 | Ccng1 | 5073 | 0.174 | 0.0134 | No |
| 32 | Pitpnb | 5104 | 0.173 | 0.0168 | No |
| 33 | Tbk1 | 5106 | 0.173 | 0.0217 | No |
| 34 | Psma3 | 5466 | 0.155 | 0.0078 | No |
| 35 | Ccnf | 5634 | 0.150 | 0.0035 | No |
| 36 | Gla | 5644 | 0.149 | 0.0073 | No |
| 37 | Acsl3 | 5772 | 0.143 | 0.0048 | No |
| 38 | Slc1a5 | 6018 | 0.133 | -0.0039 | No |
| 39 | Itgb2 | 6050 | 0.131 | -0.0018 | No |
| 40 | Psmc2 | 6141 | 0.128 | -0.0027 | No |
| 41 | Polr3g | 6258 | 0.123 | -0.0052 | No |
| 42 | Gtf2h1 | 6468 | 0.115 | -0.0126 | No |
| 43 | Mcm4 | 6565 | 0.112 | -0.0143 | No |
| 44 | Pgk1 | 6805 | 0.103 | -0.0236 | No |
| 45 | Gsk3b | 6938 | 0.098 | -0.0275 | No |
| 46 | Acaca | 7236 | 0.086 | -0.0403 | No |
| 47 | Gga2 | 7481 | 0.078 | -0.0505 | No |
| 48 | Rdh11 | 7598 | 0.074 | -0.0543 | No |
| 49 | Nmt1 | 7622 | 0.073 | -0.0534 | No |
| 50 | Psmg1 | 7896 | 0.066 | -0.0655 | No |
| 51 | Nfyc | 7929 | 0.064 | -0.0653 | No |
| 52 | Ctsc | 7956 | 0.063 | -0.0648 | No |
| 53 | Etf1 | 7985 | 0.062 | -0.0645 | No |
| 54 | Gmps | 8070 | 0.060 | -0.0671 | No |
| 55 | Shmt2 | 8245 | 0.054 | -0.0744 | No |
| 56 | Ldlr | 8303 | 0.052 | -0.0759 | No |
| 57 | Wars1 | 8339 | 0.051 | -0.0762 | No |
| 58 | Nfil3 | 8496 | 0.046 | -0.0829 | No |
| 59 | Pgm1 | 8576 | 0.044 | -0.0857 | No |
| 60 | Uchl5 | 8855 | 0.034 | -0.0989 | No |
| 61 | Psph | 8877 | 0.034 | -0.0990 | No |
| 62 | Ddit4 | 8958 | 0.031 | -0.1022 | No |
| 63 | Got1 | 8968 | 0.031 | -0.1018 | No |
| 64 | Idh1 | 9070 | 0.027 | -0.1062 | No |
| 65 | Actr3 | 9157 | 0.025 | -0.1099 | No |
| 66 | Btg2 | 9180 | 0.024 | -0.1103 | No |
| 67 | Elovl6 | 9209 | 0.023 | -0.1111 | No |
| 68 | Nufip1 | 9237 | 0.022 | -0.1119 | No |
| 69 | Pnp | 9245 | 0.021 | -0.1116 | No |
| 70 | Fads1 | 9325 | 0.018 | -0.1151 | No |
| 71 | Bhlhe40 | 9341 | 0.018 | -0.1154 | No |
| 72 | Eef1e1 | 9403 | 0.016 | -0.1180 | No |
| 73 | Tfrc | 9502 | 0.013 | -0.1227 | No |
| 74 | Atp2a2 | 9526 | 0.013 | -0.1235 | No |
| 75 | Pno1 | 9542 | 0.012 | -0.1239 | No |
| 76 | Skap2 | 9609 | 0.010 | -0.1270 | No |
| 77 | Plod2 | 9688 | 0.007 | -0.1308 | No |
| 78 | Map2k3 | 9766 | 0.004 | -0.1346 | No |
| 79 | Plk1 | 9781 | 0.004 | -0.1352 | No |
| 80 | Cdkn1a | 9815 | 0.003 | -0.1368 | No |
| 81 | Hsp90b1 | 10229 | -0.001 | -0.1579 | No |
| 82 | Tcea1 | 10270 | -0.002 | -0.1599 | No |
| 83 | Hspa9 | 10315 | -0.003 | -0.1620 | No |
| 84 | Rrm2 | 10372 | -0.005 | -0.1647 | No |
| 85 | Pfkl | 10467 | -0.008 | -0.1693 | No |
| 86 | Ddx39a | 10567 | -0.011 | -0.1740 | No |
| 87 | Psmd12 | 10595 | -0.013 | -0.1751 | No |
| 88 | Psme3 | 10699 | -0.015 | -0.1799 | No |
| 89 | Cops5 | 10947 | -0.024 | -0.1918 | No |
| 90 | Ero1a | 11021 | -0.026 | -0.1948 | No |
| 91 | Lta4h | 11039 | -0.027 | -0.1949 | No |
| 92 | Cxcr4 | 11117 | -0.029 | -0.1980 | No |
| 93 | Ak4 | 11121 | -0.030 | -0.1973 | No |
| 94 | Stard4 | 11145 | -0.030 | -0.1976 | No |
| 95 | Elovl5 | 11212 | -0.033 | -0.2000 | No |
| 96 | Uso1 | 11317 | -0.036 | -0.2043 | No |
| 97 | Mllt11 | 11328 | -0.036 | -0.2038 | No |
| 98 | Hspd1 | 11347 | -0.037 | -0.2037 | No |
| 99 | Tes | 11461 | -0.040 | -0.2083 | No |
| 100 | Hspa4 | 11585 | -0.043 | -0.2134 | No |
| 101 | Acly | 11675 | -0.046 | -0.2166 | No |
| 102 | Txnrd1 | 11845 | -0.052 | -0.2238 | No |
| 103 | Prdx1 | 11867 | -0.053 | -0.2233 | No |
| 104 | Slc6a6 | 11903 | -0.054 | -0.2236 | No |
| 105 | Fkbp2 | 12223 | -0.067 | -0.2380 | No |
| 106 | Dhcr7 | 12323 | -0.070 | -0.2410 | No |
| 107 | Dapp1 | 12342 | -0.071 | -0.2399 | No |
| 108 | Gsr | 12373 | -0.072 | -0.2394 | No |
| 109 | Hk2 | 12423 | -0.073 | -0.2398 | No |
| 110 | Sytl2 | 12497 | -0.077 | -0.2414 | No |
| 111 | Sord | 12724 | -0.084 | -0.2505 | No |
| 112 | Dhcr24 | 12739 | -0.085 | -0.2488 | No |
| 113 | Rpa1 | 12769 | -0.086 | -0.2479 | No |
| 114 | Hmgcr | 12936 | -0.092 | -0.2537 | No |
| 115 | Canx | 13088 | -0.099 | -0.2586 | No |
| 116 | Tubg1 | 13143 | -0.101 | -0.2585 | No |
| 117 | Mthfd2 | 13213 | -0.104 | -0.2591 | No |
| 118 | Sec11a | 13479 | -0.115 | -0.2694 | No |
| 119 | Rab1a | 13526 | -0.116 | -0.2684 | No |
| 120 | Pdap1 | 13535 | -0.117 | -0.2655 | No |
| 121 | Actr2 | 13642 | -0.120 | -0.2675 | No |
| 122 | Rpn1 | 13665 | -0.121 | -0.2652 | No |
| 123 | Immt | 14026 | -0.137 | -0.2797 | Yes |
| 124 | Niban1 | 14052 | -0.138 | -0.2770 | Yes |
| 125 | Mcm2 | 14092 | -0.140 | -0.2750 | Yes |
| 126 | Egln3 | 14103 | -0.140 | -0.2715 | Yes |
| 127 | Serp1 | 14123 | -0.141 | -0.2685 | Yes |
| 128 | Edem1 | 14185 | -0.144 | -0.2675 | Yes |
| 129 | Sdf2l1 | 14325 | -0.150 | -0.2703 | Yes |
| 130 | Adipor2 | 14373 | -0.152 | -0.2684 | Yes |
| 131 | Ppa1 | 14547 | -0.159 | -0.2727 | Yes |
| 132 | Asns | 14583 | -0.161 | -0.2699 | Yes |
| 133 | Arpc5l | 14632 | -0.163 | -0.2678 | Yes |
| 134 | Tpi1 | 14871 | -0.174 | -0.2750 | Yes |
| 135 | Cct6a | 14947 | -0.178 | -0.2737 | Yes |
| 136 | Ung | 14959 | -0.179 | -0.2692 | Yes |
| 137 | Slc1a4 | 14966 | -0.179 | -0.2644 | Yes |
| 138 | Ldha | 15027 | -0.182 | -0.2623 | Yes |
| 139 | Pdk1 | 15041 | -0.183 | -0.2577 | Yes |
| 140 | Rit1 | 15043 | -0.183 | -0.2526 | Yes |
| 141 | Sla | 15140 | -0.187 | -0.2522 | Yes |
| 142 | Srd5a1 | 15227 | -0.190 | -0.2512 | Yes |
| 143 | Tomm40 | 15246 | -0.191 | -0.2467 | Yes |
| 144 | G6pdx | 15385 | -0.198 | -0.2481 | Yes |
| 145 | Ssr1 | 15456 | -0.201 | -0.2459 | Yes |
| 146 | Pik3r3 | 15511 | -0.204 | -0.2429 | Yes |
| 147 | Ppia | 15573 | -0.207 | -0.2401 | Yes |
| 148 | Lgmn | 15692 | -0.212 | -0.2401 | Yes |
| 149 | Gbe1 | 15821 | -0.219 | -0.2404 | Yes |
| 150 | Calr | 15865 | -0.221 | -0.2364 | Yes |
| 151 | Cdc25a | 15897 | -0.222 | -0.2316 | Yes |
| 152 | Nfkbib | 15905 | -0.222 | -0.2257 | Yes |
| 153 | P4ha1 | 15914 | -0.223 | -0.2197 | Yes |
| 154 | Stip1 | 15944 | -0.225 | -0.2148 | Yes |
| 155 | Gpi1 | 16175 | -0.238 | -0.2198 | Yes |
| 156 | Cacybp | 16176 | -0.238 | -0.2130 | Yes |
| 157 | Atp6v1d | 16210 | -0.240 | -0.2079 | Yes |
| 158 | Psat1 | 16322 | -0.242 | -0.2067 | Yes |
| 159 | Cd9 | 16461 | -0.250 | -0.2066 | Yes |
| 160 | Ykt6 | 16499 | -0.252 | -0.2013 | Yes |
| 161 | Aldoa | 16540 | -0.255 | -0.1961 | Yes |
| 162 | Ufm1 | 16631 | -0.260 | -0.1933 | Yes |
| 163 | Ebp | 16739 | -0.267 | -0.1912 | Yes |
| 164 | Ifi30 | 16780 | -0.269 | -0.1856 | Yes |
| 165 | Nampt | 16786 | -0.270 | -0.1782 | Yes |
| 166 | Hspa5 | 16790 | -0.270 | -0.1707 | Yes |
| 167 | Psmc4 | 16797 | -0.271 | -0.1633 | Yes |
| 168 | Eif2s2 | 16854 | -0.274 | -0.1583 | Yes |
| 169 | Qdpr | 16918 | -0.278 | -0.1536 | Yes |
| 170 | Psmc6 | 16938 | -0.279 | -0.1467 | Yes |
| 171 | Ube2d3 | 17047 | -0.284 | -0.1441 | Yes |
| 172 | Slc2a1 | 17239 | -0.295 | -0.1455 | Yes |
| 173 | Fads2 | 17291 | -0.298 | -0.1396 | Yes |
| 174 | Hmgcs1 | 17430 | -0.309 | -0.1378 | Yes |
| 175 | Xbp1 | 17449 | -0.311 | -0.1299 | Yes |
| 176 | Eno1b | 17521 | -0.317 | -0.1245 | Yes |
| 177 | M6pr | 17916 | -0.346 | -0.1348 | Yes |
| 178 | Coro1a | 18040 | -0.357 | -0.1309 | Yes |
| 179 | Psmd13 | 18053 | -0.359 | -0.1213 | Yes |
| 180 | Fdxr | 18333 | -0.391 | -0.1245 | Yes |
| 181 | Rrp9 | 18396 | -0.398 | -0.1163 | Yes |
| 182 | Tmem97 | 18445 | -0.405 | -0.1073 | Yes |
| 183 | Tuba4a | 18471 | -0.408 | -0.0969 | Yes |
| 184 | Cyp51 | 18814 | -0.452 | -0.1015 | Yes |
| 185 | Ddit3 | 19101 | -0.502 | -0.1019 | Yes |
| 186 | Hspe1 | 19342 | -0.559 | -0.0982 | Yes |
| 187 | Me1 | 19430 | -0.589 | -0.0859 | Yes |
| 188 | Glrx | 19531 | -0.635 | -0.0730 | Yes |
| 189 | Psmb5 | 19605 | -0.682 | -0.0573 | Yes |
| 190 | Insig1 | 19670 | -0.748 | -0.0393 | Yes |
| 191 | Fgl2 | 19678 | -0.764 | -0.0179 | Yes |
| 192 | Hmbs | 19702 | -0.797 | 0.0035 | Yes |

