| Dataset | CMP.CMP_Pheno.cls#Group6_versus_Group8.CMP_Pheno.cls#Group6_versus_Group8_repos |
| Phenotype | CMP_Pheno.cls#Group6_versus_Group8_repos |
| Upregulated in class | 4 |
| GeneSet | HALLMARK_G2M_CHECKPOINT |
| Enrichment Score (ES) | 0.30690312 |
| Normalized Enrichment Score (NES) | 1.3407377 |
| Nominal p-value | 0.16317992 |
| FDR q-value | 0.22576806 |
| FWER p-Value | 0.657 |

| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | Ccnd1 | 226 | 0.689 | 0.0096 | Yes |
| 2 | Nek2 | 398 | 0.591 | 0.0190 | Yes |
| 3 | Kif23 | 564 | 0.562 | 0.0278 | Yes |
| 4 | Tnpo2 | 724 | 0.524 | 0.0358 | Yes |
| 5 | Pttg1 | 761 | 0.510 | 0.0496 | Yes |
| 6 | Ube2s | 788 | 0.504 | 0.0637 | Yes |
| 7 | Aurka | 826 | 0.495 | 0.0770 | Yes |
| 8 | Kif2c | 834 | 0.493 | 0.0918 | Yes |
| 9 | Cenpf | 885 | 0.480 | 0.1039 | Yes |
| 10 | Abl1 | 1098 | 0.443 | 0.1067 | Yes |
| 11 | Sqle | 1593 | 0.404 | 0.0938 | Yes |
| 12 | Slc7a5 | 1673 | 0.399 | 0.1020 | Yes |
| 13 | Cdkn3 | 1804 | 0.381 | 0.1071 | Yes |
| 14 | Mki67 | 1921 | 0.365 | 0.1124 | Yes |
| 15 | Stil | 2066 | 0.347 | 0.1156 | Yes |
| 16 | Cenpa | 2171 | 0.336 | 0.1206 | Yes |
| 17 | Ccna2 | 2172 | 0.336 | 0.1309 | Yes |
| 18 | Odc1 | 2318 | 0.321 | 0.1334 | Yes |
| 19 | Kif11 | 2494 | 0.304 | 0.1338 | Yes |
| 20 | Tfdp1 | 2501 | 0.304 | 0.1428 | Yes |
| 21 | Ccnt1 | 2515 | 0.303 | 0.1514 | Yes |
| 22 | Cdkn2c | 2566 | 0.299 | 0.1580 | Yes |
| 23 | Fancc | 2577 | 0.298 | 0.1667 | Yes |
| 24 | Upf1 | 2773 | 0.285 | 0.1654 | Yes |
| 25 | Cdc7 | 2795 | 0.283 | 0.1731 | Yes |
| 26 | Bard1 | 2801 | 0.283 | 0.1815 | Yes |
| 27 | Knl1 | 2806 | 0.282 | 0.1899 | Yes |
| 28 | Odf2 | 2824 | 0.282 | 0.1977 | Yes |
| 29 | Rasal2 | 2879 | 0.278 | 0.2035 | Yes |
| 30 | Bub3 | 2901 | 0.277 | 0.2109 | Yes |
| 31 | Troap | 3018 | 0.269 | 0.2132 | Yes |
| 32 | Cdc25b | 3160 | 0.263 | 0.2140 | Yes |
| 33 | Cenpe | 3287 | 0.258 | 0.2155 | Yes |
| 34 | Tacc3 | 3501 | 0.252 | 0.2124 | Yes |
| 35 | Hus1 | 3687 | 0.241 | 0.2103 | Yes |
| 36 | Kif4 | 3803 | 0.234 | 0.2116 | Yes |
| 37 | Polq | 3884 | 0.233 | 0.2147 | Yes |
| 38 | Bub1 | 3964 | 0.228 | 0.2176 | Yes |
| 39 | E2f3 | 4161 | 0.222 | 0.2145 | Yes |
| 40 | Wrn | 4233 | 0.218 | 0.2175 | Yes |
| 41 | Kmt5a | 4277 | 0.216 | 0.2219 | Yes |
| 42 | Plk4 | 4290 | 0.215 | 0.2279 | Yes |
| 43 | Notch2 | 4330 | 0.213 | 0.2325 | Yes |
| 44 | Hmmr | 4346 | 0.212 | 0.2382 | Yes |
| 45 | Cks2 | 4568 | 0.198 | 0.2330 | Yes |
| 46 | Numa1 | 4575 | 0.198 | 0.2388 | Yes |
| 47 | Nup50 | 4797 | 0.188 | 0.2333 | Yes |
| 48 | Xpo1 | 4829 | 0.187 | 0.2374 | Yes |
| 49 | Lig3 | 4908 | 0.183 | 0.2390 | Yes |
| 50 | Chaf1a | 4980 | 0.179 | 0.2409 | Yes |
| 51 | Orc5 | 5079 | 0.174 | 0.2412 | Yes |
| 52 | Mnat1 | 5111 | 0.173 | 0.2449 | Yes |
| 53 | Aurkb | 5115 | 0.173 | 0.2501 | Yes |
| 54 | Top2a | 5168 | 0.170 | 0.2526 | Yes |
| 55 | Cul4a | 5215 | 0.167 | 0.2554 | Yes |
| 56 | Rad21 | 5249 | 0.166 | 0.2588 | Yes |
| 57 | Cdk1 | 5269 | 0.165 | 0.2629 | Yes |
| 58 | Ube2c | 5276 | 0.165 | 0.2676 | Yes |
| 59 | Ndc80 | 5340 | 0.161 | 0.2693 | Yes |
| 60 | Pole | 5506 | 0.154 | 0.2656 | Yes |
| 61 | Incenp | 5520 | 0.153 | 0.2697 | Yes |
| 62 | Kpnb1 | 5524 | 0.153 | 0.2742 | Yes |
| 63 | Ccnf | 5634 | 0.150 | 0.2732 | Yes |
| 64 | Lmnb1 | 5661 | 0.148 | 0.2765 | Yes |
| 65 | Cul5 | 5742 | 0.144 | 0.2768 | Yes |
| 66 | Rps6ka5 | 5746 | 0.144 | 0.2811 | Yes |
| 67 | Ttk | 5834 | 0.141 | 0.2809 | Yes |
| 68 | Kif22 | 5847 | 0.140 | 0.2846 | Yes |
| 69 | Rad23b | 5861 | 0.140 | 0.2882 | Yes |
| 70 | Cdkn1b | 5894 | 0.138 | 0.2908 | Yes |
| 71 | Pml | 5921 | 0.137 | 0.2937 | Yes |
| 72 | Prc1 | 5998 | 0.134 | 0.2939 | Yes |
| 73 | Katna1 | 6024 | 0.133 | 0.2967 | Yes |
| 74 | Pola2 | 6130 | 0.128 | 0.2953 | Yes |
| 75 | Tra2b | 6134 | 0.128 | 0.2991 | Yes |
| 76 | Nasp | 6159 | 0.127 | 0.3017 | Yes |
| 77 | Ezh2 | 6181 | 0.126 | 0.3045 | Yes |
| 78 | Brca2 | 6210 | 0.125 | 0.3069 | Yes |
| 79 | Espl1 | 6404 | 0.117 | 0.3006 | No |
| 80 | Nsd2 | 6465 | 0.115 | 0.3011 | No |
| 81 | Smarcc1 | 6521 | 0.113 | 0.3018 | No |
| 82 | Ilf3 | 6563 | 0.112 | 0.3031 | No |
| 83 | Lbr | 6750 | 0.105 | 0.2968 | No |
| 84 | Traip | 6908 | 0.099 | 0.2918 | No |
| 85 | Cdc27 | 6921 | 0.098 | 0.2942 | No |
| 86 | Stag1 | 7040 | 0.094 | 0.2911 | No |
| 87 | H2az2 | 7055 | 0.093 | 0.2932 | No |
| 88 | Tpx2 | 7060 | 0.093 | 0.2959 | No |
| 89 | Stmn1 | 7256 | 0.086 | 0.2885 | No |
| 90 | Smc2 | 7370 | 0.082 | 0.2853 | No |
| 91 | Prim2 | 7401 | 0.081 | 0.2862 | No |
| 92 | Nup98 | 7475 | 0.078 | 0.2849 | No |
| 93 | Kif15 | 7641 | 0.073 | 0.2787 | No |
| 94 | Nusap1 | 7688 | 0.071 | 0.2785 | No |
| 95 | G3bp1 | 7861 | 0.067 | 0.2718 | No |
| 96 | Mcm6 | 8045 | 0.060 | 0.2643 | No |
| 97 | Cdc6 | 8172 | 0.056 | 0.2596 | No |
| 98 | Mtf2 | 8189 | 0.055 | 0.2605 | No |
| 99 | Sfpq | 8191 | 0.055 | 0.2621 | No |
| 100 | Hira | 8235 | 0.054 | 0.2615 | No |
| 101 | Foxn3 | 8279 | 0.052 | 0.2610 | No |
| 102 | Tmpo | 8563 | 0.044 | 0.2479 | No |
| 103 | Birc5 | 8574 | 0.044 | 0.2487 | No |
| 104 | Gspt1 | 8670 | 0.041 | 0.2451 | No |
| 105 | Map3k20 | 8748 | 0.037 | 0.2423 | No |
| 106 | Slc12a2 | 8796 | 0.036 | 0.2410 | No |
| 107 | Cul3 | 8848 | 0.034 | 0.2395 | No |
| 108 | Top1 | 8907 | 0.033 | 0.2375 | No |
| 109 | Smc4 | 8930 | 0.032 | 0.2373 | No |
| 110 | Rbl1 | 9202 | 0.023 | 0.2242 | No |
| 111 | Hnrnpu | 9434 | 0.015 | 0.2129 | No |
| 112 | Ythdc1 | 9528 | 0.013 | 0.2085 | No |
| 113 | Tgfb1 | 9534 | 0.012 | 0.2086 | No |
| 114 | Arid4a | 9548 | 0.012 | 0.2083 | No |
| 115 | Smad3 | 9555 | 0.012 | 0.2084 | No |
| 116 | Racgap1 | 9730 | 0.006 | 0.1997 | No |
| 117 | Mybl2 | 9776 | 0.004 | 0.1975 | No |
| 118 | Plk1 | 9781 | 0.004 | 0.1974 | No |
| 119 | Kif20b | 9876 | 0.001 | 0.1926 | No |
| 120 | Meis2 | 10240 | -0.001 | 0.1741 | No |
| 121 | Mad2l1 | 10249 | -0.001 | 0.1738 | No |
| 122 | Mapk14 | 10345 | -0.004 | 0.1690 | No |
| 123 | Hmgb3 | 10396 | -0.006 | 0.1667 | No |
| 124 | H2ax | 10523 | -0.010 | 0.1605 | No |
| 125 | Syncrip | 10531 | -0.010 | 0.1605 | No |
| 126 | Ddx39a | 10567 | -0.011 | 0.1590 | No |
| 127 | Atrx | 10783 | -0.018 | 0.1486 | No |
| 128 | Bcl3 | 10849 | -0.021 | 0.1459 | No |
| 129 | Tent4a | 10881 | -0.022 | 0.1450 | No |
| 130 | E2f4 | 10976 | -0.025 | 0.1410 | No |
| 131 | Srsf2 | 11004 | -0.026 | 0.1404 | No |
| 132 | Tle3 | 11304 | -0.036 | 0.1262 | No |
| 133 | Kif5b | 11403 | -0.039 | 0.1224 | No |
| 134 | E2f1 | 11415 | -0.039 | 0.1230 | No |
| 135 | Snrpd1 | 11535 | -0.042 | 0.1182 | No |
| 136 | Dr1 | 11568 | -0.043 | 0.1179 | No |
| 137 | Ccnb2 | 11619 | -0.044 | 0.1167 | No |
| 138 | Srsf10 | 11653 | -0.045 | 0.1164 | No |
| 139 | Ncl | 11681 | -0.046 | 0.1164 | No |
| 140 | Dmd | 11695 | -0.046 | 0.1172 | No |
| 141 | Cdk4 | 11737 | -0.048 | 0.1166 | No |
| 142 | Pds5b | 12090 | -0.062 | 0.1005 | No |
| 143 | Hif1a | 12165 | -0.064 | 0.0987 | No |
| 144 | Rad54l | 12166 | -0.064 | 0.1006 | No |
| 145 | Dkc1 | 12255 | -0.068 | 0.0982 | No |
| 146 | Hspa8 | 12348 | -0.071 | 0.0957 | No |
| 147 | Cul1 | 12363 | -0.072 | 0.0972 | No |
| 148 | Mcm3 | 12368 | -0.072 | 0.0992 | No |
| 149 | Egf | 12449 | -0.074 | 0.0974 | No |
| 150 | Prpf4b | 12710 | -0.084 | 0.0867 | No |
| 151 | H2az1 | 12872 | -0.089 | 0.0812 | No |
| 152 | Smc1a | 13005 | -0.095 | 0.0774 | No |
| 153 | Fbxo5 | 13051 | -0.097 | 0.0780 | No |
| 154 | Ctcf | 13087 | -0.099 | 0.0793 | No |
| 155 | Dbf4 | 13145 | -0.101 | 0.0795 | No |
| 156 | E2f2 | 13274 | -0.107 | 0.0762 | No |
| 157 | Meis1 | 13353 | -0.110 | 0.0756 | No |
| 158 | Casp8ap2 | 13449 | -0.113 | 0.0742 | No |
| 159 | Pbk | 13450 | -0.113 | 0.0777 | No |
| 160 | Uck2 | 13466 | -0.114 | 0.0804 | No |
| 161 | Mcm5 | 13546 | -0.117 | 0.0799 | No |
| 162 | Pafah1b1 | 13837 | -0.129 | 0.0691 | No |
| 163 | Ewsr1 | 14049 | -0.138 | 0.0626 | No |
| 164 | Mcm2 | 14092 | -0.140 | 0.0647 | No |
| 165 | Cdc20 | 14176 | -0.144 | 0.0649 | No |
| 166 | Efna5 | 14314 | -0.150 | 0.0625 | No |
| 167 | Gins2 | 14420 | -0.154 | 0.0618 | No |
| 168 | Slc38a1 | 14567 | -0.160 | 0.0593 | No |
| 169 | Chek1 | 14569 | -0.160 | 0.0641 | No |
| 170 | Marcks | 14620 | -0.162 | 0.0665 | No |
| 171 | Cdc45 | 14623 | -0.162 | 0.0714 | No |
| 172 | Exo1 | 14951 | -0.179 | 0.0602 | No |
| 173 | Atf5 | 14956 | -0.179 | 0.0655 | No |
| 174 | Sap30 | 15053 | -0.184 | 0.0662 | No |
| 175 | Cbx1 | 15085 | -0.185 | 0.0703 | No |
| 176 | Chmp1a | 15214 | -0.190 | 0.0696 | No |
| 177 | Ss18 | 15299 | -0.194 | 0.0712 | No |
| 178 | Rpa2 | 15651 | -0.211 | 0.0598 | No |
| 179 | Hnrnpd | 15844 | -0.220 | 0.0567 | No |
| 180 | Cdc25a | 15897 | -0.222 | 0.0609 | No |
| 181 | Slc7a1 | 16094 | -0.233 | 0.0580 | No |
| 182 | Srsf1 | 16122 | -0.235 | 0.0638 | No |
| 183 | Amd1 | 16203 | -0.239 | 0.0671 | No |
| 184 | Jpt1 | 16366 | -0.245 | 0.0663 | No |
| 185 | Suv39h1 | 16387 | -0.246 | 0.0728 | No |
| 186 | Dtymk | 16970 | -0.282 | 0.0518 | No |
| 187 | Pura | 17159 | -0.290 | 0.0511 | No |
| 188 | H2bc12 | 17409 | -0.307 | 0.0478 | No |
| 189 | Nolc1 | 17424 | -0.309 | 0.0565 | No |
| 190 | Hmga1b | 17777 | -0.333 | 0.0488 | No |
| 191 | Orc6 | 18136 | -0.367 | 0.0417 | No |
| 192 | Prmt5 | 18514 | -0.415 | 0.0352 | No |
| 193 | Myc | 18782 | -0.448 | 0.0353 | No |
| 194 | Cks1b | 19063 | -0.495 | 0.0362 | No |

